Clinical trials: Emergency Department Presentation
Severe Sepsis and Septic Shock
Statistical Analysis Plan for an Individual Patient Data Meta-analysis of Three, International Trials Comparing Protocolised With Usual Resuscitation in Patients Presenting to the Emergency Department With Severe Sepsis and Septic Shock
This is the statistical analysis plan for an individual patient data meta-analysis (IPDMA) of three EGDT clinical trials.
- Trial name
- NCT02030158
- Volunteers
- 4,210 people
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Children Referred to the Pediatric Emergency Department
The Effect of Medical Clowns on Blood Pressure Measurement in Children Presenting to the Emergency Department
Obtaining vital signs and blood pressure (BP) in particularly, as part of a pediatric Emergency Department (ED) patient triage is sometimes difficult and leads to many false negative results.
- Trial name
- NCT03143088
- Testing
- Medical clown
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Low Back Pain, Acute
Interfascial Infiltration for Acute Unspecific Low Back Pain in the Emergency Department
Pain relief and functional impairment have been shown to remain poor to moderate over weeks after emergency department discharge, in patients who seek ED management for acute nontraumatic, nonradicular low back pain.
- Trial name
- PreSosLumbago (NCT03968185)
- Testing
- Interfascial infiltration, Standard medical treatment
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
Frailty, Length of Stay
Evaluation of Prioritized Assessment for Older Patients Living With Frailty Presenting to the Emergency Department
The older population is getting older and growing in size worldwide. This requires healthcare to adapt to meet the complex medical and nursing needs of the older patient group.
- Conditions
- Frailty, Length of Stay, Emergency Department Visit, Older Patients
- Trial name
- NCT06869148
- Testing
- Prioritized assessment for older patients living with frailty
- Where
- Sweden
- Volunteers
- 1,217 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
End-Tidal Carbon Dioxide Measurement, Capnography
Comparison of Capnography and Blood Gas PaCO₂ Measurements
Capnography provides continuous, non-invasive assessment of ventilation by measuring end-tidal carbon dioxide (EtCO₂). Different capnographic technologies, including mainstream, sidestream, and microstream capnography, may…
- Trial name
- CAPNO-PaCO2 (NCT07834411)
- Testing
- Mainstream Capnography, Sidestream Capnography, Microstream Capnography
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Intentional Self-Harm, Suicide
BEACON Suicide Prevention in Men Study
The purpose of this study is to evaluate the use of problem-solving therapy (PST), supplemented by a smartphone application, in the treatment of men who present to the Emergency Departments in Ontario.
- Trial name
- NCT03473535
- Testing
- BEACON + Problem Solving Therapy, Problem-Solving Therapy
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Ottawa
Chest Pain
Acute Chest Pain Treatment and Evaluation (ACTION) Study
Objective 1. To compare the incidence of adverse cardiac events among the patients discharged after evaluation through ACTION protocol with those through conventional protocol.
- Trial name
- NCT00434564
- Testing
- Stress nuclear scan
- Where
- Singapore
- Volunteers
- 1,690 people
- Sponsor
- Singapore General Hospital
Type 2 Diabetes, Hyperglycemia
Enhancing Preventative Health Behaviors Among Emergency Department Hyperglycemic Patients
The goal of this clinical trial is to increase Type 2 Diabetes Mellitus knowledge and awareness among patients who present to the Emergency Department with hyperglycemia.
- Trial name
- NCT06663813
- Testing
- Educational Intervention
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- Rutgers, The State University of New Jersey
Acute Kidney Injury
Biomarker Rule in/Out in Patients With Acute Diseases for Validation of AKI (BRAVA) Acute Kidney Injury
The presence or development of AKI impacts on outcomes in patients presenting with acute conditions to the ED. As a result, treating physicians are often concerned with the risk of AKI and take such risk in consideration when…
- Trial name
- BRAVA (NCT03754023)
- Testing
- Urine-TIMP-IGFBP7 biomarker for AKI
- Where
- 5 sites in Australia, India and 3 more
- Volunteers
- 818 people
- Sponsor
- GREAT Network Italy
Chest Pain
Rapid Diagnosis of Patients With Chest Pain During the Covid-19 Outbreak (My-ABCDE)
During the outbreak of COVID-19, among patients with chest tightness and chest pain as the main symptoms in major medical institutions in Shanghai, China, the past medical history and rapid testing were used to quickly identify…
- Trial name
- My-ABCDE (NCT05394038)
- Testing
- None，observational study.
- Where
- China
- Volunteers
- 2,218 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
Oropharyngeal Dysphagia
Oral and Swallowing Function in Older Adults
The purpose of this study is to learn about oral and swallowing function in older adults presenting to the emergency department.
- Trial name
- NCT06368830
- Testing
- 3-ounce water swallow test, Kayser-Jones Brief Oral Health Status Examination (BOHSE), Tongue pressure
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- University of Wisconsin, Madison
Fever, Reduction in Temperature
The Antipyretic Efficacy of Oral and Intravenous Paracetamol and Intramuscular Diclofenac in Patients Presenting With Fever.
A randomized clinical trial to check the antipyretic efficacy of oral and intravenous paracetamol and intramuscular diclofenac sodium in patients presenting with fever to emergency department.
- Trial name
- NCT01891435
- Testing
- Oral paracetamol, Intravenous paracetamol, Intramuscular diclofenac
- Where
- Qatar
- Volunteers
- 434 people
- Sponsor
- Hamad Medical Corporation
Shock, Hyopvolemia
Femoral Vein, Internal Jugular Vein and Inferior Vein Cava Collapsibility Indices in Polytrauma Patients by Sonographic Evaluation Before and After Resuscitation.
The aim of this study is to evaluate correlation between the collapsibility indices of the FV or IJV to IVC-CI among polytrauma patients presenting to the ED by sonographic evaluation before and after resuscitation.
- Trial name
- NCT07264374
- Testing
- Ultrasound assesment of FV,IJV and IVC collabsibillity indecis
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Pain
A Comparison of Proprietary Formulations of Oral Ketamine + Aspirin and Oral Ketamine Alone for Musculoskeletal Pain
Acute Pain is one of the most frequent chief complaints and the main reason for visiting the Emergency Department (ED). The acute pain in the ED is largely prevalent across the country with recent literature demonstrating that…
- Trial name
- NCT04860804
- Testing
- Aspirin and Ketamine, Oral Ketamine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Antonios Likourezos
Febrile Neutropenia, Drug-Induced
Predictive Value of ProCalcitonin for the Detection of Bacteraemia in Patients Presenting to the Emergency Department for Low Risk Chemo-induced Febrile Neutropenia
CALIF study is a monocentric observational study which aim is to analyse the value of adding procalcitonin (PCT, a pre-hormon increased in bacterial infection and septicaemia) in the management of chemo-induced febrile…
- Trial name
- CALIF (NCT03182465)
- Testing
- Value of ProCalcitonin
- Where
- Belgium
- Volunteers
- 54 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
TBI (Traumatic Brain Injury), Implementation Research
Emergency Department Implementation of the i-STAT Alinity Traumatic Brain Injury Whole Blood Test
The objective of this study is to identify determinants for implementing the i-STAT Alinity whole blood traumatic brain injury (TBI) test for its Food and Drug Administration (FDA)-indicated use and to evaluate other potential…
- Trial name
- EDI (NCT07373509)
- Testing
- i-STAT Alinity TBI test
- Where
- United States
- Volunteers
- 340 people
- Sponsor
- Shawn Eagle
Unspecified Child Maltreatment, Suspected, Unspecified Child Maltreatment, Confirmed
Durham Connects RCT Evaluation
The aim of this randomized controlled trial (RCT) is to evaluate the impact and mechanisms of the Durham Connects (DC) brief universal nurse home-visiting program to prevent child maltreatment and improve child well-being.
- Trial name
- NCT01406184
- Testing
- Durham Connects
- Where
- United States
- Volunteers
- 2,329 people
- Sponsor
- Duke University
Hip Fracture
Comparative Study of Analgesic Effect of Ultrasound Guided PENG Block vs FEMORAL BLOCK in Hip Fracture
To study the analgesic effect of ultrasound guided PENG Block vs Femoral nerve block in patients with Hip fracture presenting to Emergency department
- Trial name
- NCT06311630
- Where
- India
- Volunteers
- 70 people
- Sponsor
- Jubilee Mission Medical College and Research Institute
Severe Sepsis, Septic Shock
Minimally-Invasive Cardiovascular Hemodynamic Optimization (MiCHO) Versus Early Goal-Directed Therapy (EGDT) in the Management of Septic Shock
Early intervention in the treatment of septic shock, including early goal-directed therapy (EGDT) in the first 6 hours of disease presentation, has been shown to significantly decrease mortality.
- Trial name
- MiCHO (NCT00535821)
- Testing
- Esophageal Doppler monitoring - CardioQ, Deltex Inc, Central line with CVP and continuous ScvO2 monitoring
- Where
- 4 sites in United States
- Volunteers
- 5 people
- Sponsor
- Loma Linda University
Fever
Fever Education Given to Parents of Children Presenting to the Emergency Department With Fever
Fever is a common symptom of childhood, especially between the ages of one and five, and is the main reason for emergency room visits.
- Trial name
- NCT06599853
- Testing
- Fever Education
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Merve YETİMOĞLU