Clinical trials: Emergency Department Presentation
Acute Agitation
Medical Monitoring for Agitated Patients Pilot RCT - Medical Monitoring
The Psychiatric Emergency Services (PES) is an under researched area of clinical practice, largely in the management of acutely agitated and violent patients.
- Trial name
- NCT02512705
- Testing
- Pinel Restraints, Seclusion Room
- Volunteers
- 90 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Injuries and Wounds
A Trial of Topical Aloe Vera Gel in Emergency Department Patients Presenting With Simple Traumatic Wounds
This is a double blind placebo-controlled RCT comparing the speed of healing of simple traumatic wounds with Aloe Vera gel compared to both control (Ultrasound gel) and standard care.
- Trial name
- ALOE (NCT02819817)
- Testing
- Aloe Vera Gel, Ultrasound gel
- Where
- United Kingdom
- Sponsor
- NHS Lothian
Pain
An Efficacy and Safety of Proprietary Formulations of Oral Ketamine + Aspirin in Treatment of Acute Headache
Headaches affect over 50% of patients annually, with close to 4% of ED visits for headache. Most headaches managed in the ED are benign, with 90% of these headaches classified as tension, migraine, or cluster.
- Trial name
- NCT04860713
- Testing
- aspirin and ketamine, Nurtec (Rimegepant)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Antonios Likourezos
Emergencies
The Diagnostic Value of the First Clinical Impression of Patients Presenting to the Emergency Department (PREKEYDIA)
Finding a diagnosis for acutely ill patients places high demands on emergency medical personnel. While anamnesis and clinical examination provide initial indications and allow a tentative diagnosis, both laboratory chemistry and…
- Trial name
- NCT05597059
- Testing
- Machine Learning Prediction
- Where
- Austria
- Volunteers
- 1,506 people, healthy volunteers welcome
- Sponsor
- Kepler University Hospital
Renal Colic
Acupuncture Versus Titrated Morphine in Patients With Renal Colic
The aim of this study is to compare the clinical efficacy and safety profiles of a 30 minutes acupuncture session performed at an ER of a tertiary hospital versus titrated intravenous morphine in the management of acute severe…
- Trial name
- AcuRC (NCT02781415)
- Testing
- Traditional Acupuncture Session, Morphine Titration
- Where
- Tunisia
- Volunteers
- 200 people
- Sponsor
- University of Monastir
Sore Throat
Comparison of the Efficacy of Intravenous Dexketoprofen and Paracetamol in the Treatment of Sore Throat
Currently, paracetamol and nonsteroidal antiinflammatory drugs are widely used by emergency physicians in Turkey for the treatment of sore throat.
- Trial name
- NCT03768882
- Testing
- paracetamol, Dexketoprofen
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Pamukkale University
Intentional Self-Harm, Suicide
The BEACON Study: Smartphone-Assisted Problem-Solving Therapy in Men Presenting to the ED With Self-Harm (Protocol A)
This study evaluates the effectiveness of a smartphone-assisted problem-solving therapy (PST) service across Emergency Departments in Ontario.
- Trial name
- NCT03489382
- Testing
- Smartphone Assisted PST
- Where
- Canada
- Sponsor
- University of Ottawa
Chest Pain, Emergency Medicine
A Study to Assess the Accuracy of Magnetocardiography (MCG) to Diagnose True Ischemia in Patients With Chest Pain in the ED
The purpose of the research is to see if patients that come to the Emergency Department with chest pain can be more accurately and more quickly diagnosed by magnetocardiography (MCG) to see if their chest pain is caused by…
- Trial name
- MCG (NCT05809648)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Mayo Clinic
Emergency Department Patients, Pulmonary Hypertension
Pulmonary Artery Pressure in Predicting Pulmonary Embolism in Patients Presenting To The Emergency Department With Dyspnea
The aim of this study is to determine the usability of echocardiographic PAP changes obtained from emergency department records in the early risk stratification of pulmonary embolism.
- Conditions
- Emergency Department Patients, Pulmonary Hypertension, Pulmonary Embolism
- Trial name
- NCT07641400
- Testing
- Pulmonary embolism (+), pulmonary embolism (-)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Antalya Health Sciences University
Rib Fracture Multiple
Serratus Anterior Plane Block for Improving Pain and Respiratory Function in Patients With Multiple Rib Fractures
This is an observational study which will evaluate the efficacy of the serratus anterior plane block for treating pain and respiratory capacity in patients with multiple rib fractures.
- Trial name
- NCT04311827
- Testing
- Serratus Anterior Plane Block
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Stanford University
Brain Injuries
Point-Of-Care TBI Detection System For Head Injured Patients In The Emergency Department
A prospective, non-randomized trial for the extension and replication of the development database of brain electrical activity recordings and clinical information collected from patients who present to the ED following closed…
- Trial name
- READ-TBI (NCT02367274)
- Testing
- BrainScope Ahead 200
- Where
- 11 sites in United States
- Volunteers
- 421 people
- Sponsor
- BrainScope Company, Inc.
Atmospheric Pressure; Adverse Effect, GastroIntestinal Bleeding
Gastrointestinal Bleeding and Atmospheric Pressure Relationship
This study aims to investigate whether atmospheric pressure has an effect on upper gastrointestinal bleeding (UGIB), which includes causes such as peptic ulcer disease, esophagitis, gastritis, gastrointestinal varices…
- Trial name
- NCT06515353
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Saglik Bilimleri Universitesi
Renal Colic, Flank Pain
Evaluation of the Effects of Ketorolac Dose on Duration of Analgesia in Emergency Department (ED) Renal Colic Patients
This is a prospective interventional study examining the effect of ketorolac at doses of 15mg versus 30 mg for duration of analgesia in emergency department patients with suspected renal colic.
- Conditions
- Renal Colic, Flank Pain, Emergencies, Analgesia
- Trial name
- NCT05776953
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Hackensack Meridian Health
Presyncope, Arrhythmias, Cardiac
The IPED (Investigation of Palpitations in the ED) Study
Palpitations (noticeable pounding, fluttering or irregular heart beat) and pre-syncope (near blackout) are common ED problems sometimes due to an abnormal cardiac rhythm.
- Conditions
- Presyncope, Arrhythmias, Cardiac, Tachycardia, Supraventricular, Atrial Fibrillation
- Trial name
- IPED (NCT02783898)
- Testing
- AliveCor Heart Monitor
- Where
- 10 sites in United Kingdom
- Volunteers
- 243 people
- Sponsor
- NHS Lothian
Fear
Effect of Using a Dragon Design Nebulizer Mask on Treatment Duration, Compliance and Fear in Children
Incorporating playful elements into medical devices has been shown to enhance the overall experience for pediatric patients. Children want a healthcare setting that is spacious, creative, imaginative, and contemporary.
- Trial name
- NCT06568120
- Testing
- dragon themed nebulizer masks
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Koç University
Sickle-Cell Disease With Crisis
DSUVIA in Patients With SCD VOC Present in the ED
This is an observational study to improve the treatment of patients with Sickle Cell Disease Vaso-Occlusive Crisis by administering pain medications more quickly after the patient arrives in the emergency department.
- Trial name
- NCT05388188
- Testing
- sublingual sufentanil
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Jason Wilson
Heart Failure
Blood Collection of Patient Presenting in the ED and Prescribed a BNP
Plasma specimen collected from patients presenting in the Emergency Department (ED) with or without Heart Failure (HF) and prescribed a BNP.
- Trial name
- BNP (NCT02614209)
- Testing
- In Vitro diagnostic tests
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- Fujirebio Diagnostics, Inc.
Inflammation
Role of Faecal Calprotectin in Patients With Abdominal Pain
The evaluation of patients with abdominal pain is a challenge for the emergency physician and the selection of patients for second-level radiological examinations or endoscopic procedures is not always easy to perform.
- Trial name
- NCT05795985
- Testing
- calprotectin levels
- Where
- Italy
- Volunteers
- 146 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Acute Abdomen, Emergency Surgery
Primary Cecal Pathologies Presenting as Acute Abdomen
Background: The importance of cecal pathologies lie in the fact that being the first part of large intestine, any disease involving the cecum affects overall functioning of the large bowel.
- Conditions
- Acute Abdomen, Emergency Surgery, Laparotomy, Amoebic Colitis
- Trial name
- NCT03262025
- Testing
- Operated
- Volunteers
- 43 people
- Sponsor
- Jawaharlal Nehru Medical College
Acute Vaso Occlusive Crisis (VOC)
L-citrulline Injection in Patients Aged 6-21 Years Old with Sickle Cell Disease Presenting with Vaso-Occlusive Crisis (VOC)
The purpose of this study is to determine if intravenous L-citrulline can abrogate an active vaso-occlusive crisis in sickle cell disease, resulting in decreased pain, reduction or elimination of opiate usage, and reduction or…
- Trial name
- NCT04852172
- Testing
- L-citrulline, D5 1/2NS
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Asklepion Pharmaceuticals, LLC