Clinical trials: Emergency Departments
Abscess
Antibiotics Versus Placebo in the Treatment of Abscesses in the Emergency Department
The purpose of this study is to determine if there is a difference between an antibiotic, trimethoprim-sulfamethoxazole versus placebo in healing outcomes of soft tissue abscesses following incision and drainage.
- Trial name
- NCT00867789
- Testing
- Trimethoprim-sulfamethoxazole, Sugar pill
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Pain
Low-dose Ketamine for Acute Pain in the Emergency Department
This study aims to determine the efficacy and safety of low dose ketamine in association with IV morphine in the management of acute moderate to severe pain in emergency department.
- Trial name
- NCT03017248
- Testing
- Ketamine, Morphine
- Where
- Tunisia
- Volunteers
- 125 people
- Sponsor
- Faculty of Medicine, Sousse
Iatrogenic Effect
Effect of the Use of a Therapeutic Conciliation Document at the Outlet of Hospital, on the Emergency Use of Hospital Care in Patient Aged Over 75 Years Old.
The drug iatrogenesis represents an important public health problem. In the Iatromed project, we want to to assess a specific therapeutic drug conciliation sheet (TDC).
- Trial name
- IATROMED (NCT02916836)
- Testing
- therapeutic drug conciliation sheet (TDC), No Use of therapeutic drug conciliation sheet (TDC)
- Sponsor
- Centre Hospitalier Universitaire de Nice
Corneal Abrasions
IN PATIENTS WITH CORNEAL ABRASIONS TREATED WITH COLLAGEN CORNEAL SHIELDS IN THE EMERGENCY DEPARTMENT SETTING
This is a single-center, double-arm, patient masked, randomized controlled trial. Subjects will be enrolled in the Emergency Department at the Penn State Milton S. Hershey Medical Center.
- Trial name
- NCT07225699
- Testing
- Oasis 72-Hour collagen shield
- Volunteers
- 60 people
- Sponsor
- Milton S. Hershey Medical Center
Pneumonia
Pilot Study to Study the Time Between Pleuropulmonary Ultrasound and Antibiotic Therapy Prescription in Patients Admitted to the Emergency Department for Suspected Pneumonia
Pneumonia is a common pathology with significant morbidity and mortality. It is recommended in his diagnostic approach to perform either a chest X-ray or a pleuropulmonary ultrasound.
- Trial name
- PRE-EPPA (NCT07703852)
- Testing
- Pleuropulmonary ultrasound performed by the investigator for patient with suspicion od Pneumonia
- Volunteers
- 15 people
- Sponsor
- University Hospital, Grenoble
Pain Management
IBUPAP Study for Pain Management in Children
Current literature supports ibuprofen and APAP are the most commonly used analgesics in the pediatric ED for acute traumatic/non-traumatic pain.
- Trial name
- NCT03088800
- Testing
- Ibuprofen, APAP
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Antonios Likourezos
Migraine
Oral Dexamethasone for Treatment of Migraine
The aim of this project is to determine if a single dose of oral dexamethasone at the time of discharge from the emergency department (ED) [after successful treatment] prevents rebound headache.
- Trial name
- NCT00216736
- Testing
- Dexamethasone
- Where
- Australia
- Volunteers
- 63 people
- Sponsor
- The Joseph Epstein Centre for Emergency Medicine Research
COPD
Palliative Care Health Literacy Education and QOL Compared to Usual Care
The goal of this pilot randomized controlled trial is to compare health literacy (HL) and quality of life (QOL) among older adults with chronic obstructive pulmonary disease (COPD) who completed a series of standardized…
- Trial name
- PACED (NCT06089499)
- Testing
- Get Palliative Care: four educational learning module videos
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Missouri, Kansas City
Antimicrobial Stewardship, Acute Bronchitis
Using Behavioral Science to Reduce Inappropriate Antibiotic Use in Acute Care Settings
Stepped wedge behavioral intervention clinical trial looking at the impact of an antibiotic stewardship intervention on provider prescribing behavior for acute respiratory infections (ARIs), where the intervention is administered…
- Conditions
- Antimicrobial Stewardship, Acute Bronchitis, Upper Respiratory Infection
- Trial name
- NCT03711292
- Testing
- Antibiotic Stewardship
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Emergency Department Discharge Communication
Examining the Effectiveness and Implementation of the Emergency Department Patient-Activated Transition to Care At Home Tool
The goal of this clinical trial is to examine the effectiveness and implementation of the Emergency Department Patient-Activated Transition to Care at Home (ED-PATCH) tool, which is used by patients to manage information during…
- Trial name
- ED-PATCH (NCT06668636)
- Testing
- ED-PATCH
- Where
- 2 sites in Canada
- Volunteers
- 12,000 people
- Sponsor
- IWK Health Centre
Altered Mental Status, Generalized Nonconvulsive Seizure Disorder
Putting Electroencephalography (EEG) in the Emergency Department
The aim of the proposed research is to compare the diagnostic accuracy of a portable wireless electroencephalography (EEG) device (Biosignal Micro-EEG) to standard EEG in identifying abnormal EEG patterns (mainly non-convulsive…
- Conditions
- Altered Mental Status, Generalized Nonconvulsive Seizure Disorder, Status-epilepticus
- Trial name
- NCT01355211
- Where
- United States
- Volunteers
- 261 people
- Sponsor
- Bio-Signal Group Corp.
Cardiopulmonary Resuscitation
Manual and Mechanical Chest Compression During In-hospital Witnessed Cardiac Arrests Using Cerebral Oximetry
Post-resuscitation neurological impairment is associated with morbidity and especially with late mortality. Thus, because good neurological outcome is vital for a successful resuscitation, it is essential to have sufficient…
- Trial name
- NCT03238287
- Testing
- Mechanical chest compression, Manuel chest compression
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Eskisehir Osmangazi University
Smoking Cessation, Emergency Department Visit
Acute Respiratory Disease as a Fulcrum Point to Quit Smoking: Evaluation of an ED-based Intervention
This study aims to evaluate smoking cessation success rates using the Fagerström Test for Nicotine Dependence (FTND) in smoking cessation treatment.
- Conditions
- Smoking Cessation, Emergency Department Visit, Acute Respiratory Infections (ARIs)
- Trial name
- Intervention (NCT06923852)
- Testing
- Smoking cessation support that World Health Organization (WHO) 5A model (Ask, Advise, Assess, Assist, Arrange).
- Volunteers
- 288 people
- Sponsor
- Seda Oğuz
Chest Pain, Cough
Accuracy of Ultra-Low-Dose-CT of the Chest Compared to Plain Film in an Unfiltered Emergency Department Patient Cohort
This trial compares the accuracy provided by plain film as well as ultra-low-dose-computed-tomography (ULDCT) of the chest. It also aims to analyze differences in diagnostic confidence and therapeutic consequence offered by these…
- Conditions
- Chest Pain, Cough, Thoracic Diseases, Lung Diseases
- Trial name
- UP-Chest (NCT03922516)
- Testing
- ULDCT
- Where
- Austria
- Volunteers
- 295 people
- Sponsor
- Medical University of Vienna
Hip Fractures, Pain, Acute
Pericapsular Nerve Group Block for Hip Fractures
This will be a feasibility study to see if it feasible to perform the Pericapsular Nerve Group Block for hip fractures in the Emergency Department.
- Trial name
- NCT04882384
- Testing
- Pericapsular Nerve Group Block
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Jacobi Medical Center
Cardiac Arrest, Heart Arrest
ECPR for Refractory Out-Of-Hospital Cardiac Arrest
In the U.S. alone, over 300,000 people per year have sudden out-of-hospital cardiac arrest (OHCA), and less than 1 out of 10 survive.
- Conditions
- Cardiac Arrest, Heart Arrest, Sudden Cardiac Arrest, Cardiopulmonary Arrest
- Trial name
- EROCA (NCT03065647)
- Testing
- Expedited Transport With Mechanical CPR
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Michigan
Myocardial Infarction, Chest Pain
AI-based Decision Support in Acute Chest Pain
The AIDE-CP1 trial will test whether a decision support tool based on artificial intelligence (AI) can improve care for patients who come to an emergency department with chest pain.
- Trial name
- AIDE-CP1 (NCT07864038)
- Testing
- AIDE-CP available
- Volunteers
- 4,500 people
- Sponsor
- Region Skane
Emergency Room
A Study to Evaluate the Impact of Classical Music on Perceived Waiting Time and Satisfaction in Emergency Department Patients
The goal of this study is to evaluate whether classical music in the Emergency waiting room can diminish perception of waiting times.
- Trial name
- MORAL (NCT06973993)
- Testing
- live music, recorded music, no music
- Where
- Switzerland
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Sepsis
Comparing Prognostic Performance of SEPSIS 2 and SEPSIS 3 Strategies at the Emergency Service
In 2016, the Third International Consensus proposed a new strategy to screen aggravating risk in patients with septic shock. This strategy is based on quick-SOFA and the SOFA score.
- Trial name
- StraSEP (NCT03355833)
- Volunteers
- 228 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Acute Coronary Syndrome
VitalScan MCG Rule-out Multi-centre Pivotal Study - US
A prospective multi-centre observational study to validate the diagnostic accuracy of a transportable magnetocardiograph device for acute coronary syndrome (ACS), focusing on rule-out capability, in patients who present to the…
- Trial name
- MAGNET ACS (NCT03546933)
- Testing
- VitalScan Magnetocardiograph
- Where
- 5 sites in United States
- Volunteers
- 651 people
- Sponsor
- Creavo Medical Technologies Ltd
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