Clinical trials: Emergency Surgery Patients
Patient Presented With Acute Abdomen, Patient Undergoing Urgent GIT Surgery
Conventional VS Enhanced Recovery After Surgery Protocols in Emergency GIT Surgery
Although the ERAS program is widely used in elective procedures in many surgical subspecialties, the place of this program in emergency surgery remains uncertain probably because of the significant challenges in applying all ERAS…
- Trial name
- NCT04584060
- Testing
- ERAS protocols, Early oral feeding, Prophylaxis against DVT
- Volunteers
- 60 people
- Sponsor
- Assiut University
One Hundred Patients Aged 65 and Older Who Underwent Emergency General Surgical Interventions, Clinical Utility of These Scoring Systems
A Comparative Study of CCI, EmSFI, and FTRST Scoring Systems
Frailty assessment tools and comorbidity indices play a crucial role, particularly in predicting outcomes for elderly patients undergoing emergency surgery.
- Conditions
- One Hundred Patients Aged 65 and Older Who Underwent Emergency General Surgical Interventions, Clinical Utility of These Scoring Systems, Gastrointestinal Neoplasms, Appendicitis Acute
- Trial name
- NCT06943924
- Testing
- Frailty assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Postoperative Complications
Predictive Model for Postoperative Mortality
Surgery has risk of morbidity and mortality. Risk factors include: patient factors; surgical factors; and anesthetic factors. The risk is much higher in emergency cases.
- Trial name
- NCT02947789
- Testing
- Emergency surgery
- Where
- Thailand
- Volunteers
- 740 people
- Sponsor
- Khon Kaen University
Emergencies, Frail Older Adult
Emergency Laparotomy and Frailty Study
Patients aged over 65 comprise more than half the emergency general surgical workload, however, available risk-prediction tools for such patients are extrapolated from younger cohorts.
- Conditions
- Emergencies, Frail Older Adult, Laparotomy
- Trial name
- ELF (NCT02952430)
- Testing
- Emergency laparotomy
- Volunteers
- 500 people
- Sponsor
- North Western Research Collaborative
Postoperative Death
Descriptive and Risk Factors Analysis of All-cause Postoperative Death in Patients Undergoing Elective Surgery
The investigators are aimed to develop and externally validate a prediction model of clinical risk factors that quantifies postoperative death after elective surgery.
- Trial name
- NCT04929886
- Where
- 5 sites in China
- Volunteers
- 1,000,000 people
- Sponsor
- Huazhong University of Science and Technology
Anxiety
The Effect of Virtual Reality Glasses Applied During Emergency Surgical Intervention
This randomized controlled trial evaluates the effect of virtual reality glasses applied during emergency surgical intervention with local anesthesia on patients anxiety.
- Trial name
- Virtual (NCT05253274)
- Testing
- Virtual Reality Glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Mersin University
Postoperative Nausea and Vomiting
A Study of Vestipitant (GW597599) in the Treatment of Breakthrough Postoperative Nausea and Vomiting (PONV)
This study will evaluate single IV doses of Vestipitant (GW597599) compared to 4 mg IV ondansetron for treating breakthrough postoperative nausea and vomiting (PONV) after failure of PONV prophylaxis with a regimen that includes…
- Trial name
- NCT01507194
- Testing
- Ondansetron, Vestipitant
- Where
- 7 sites in United States
- Volunteers
- 131 people
- Sponsor
- Accenture
Emergencies, Surgery
The Use of Ventriject to Assess V02Max in Patients Admitted to Hospital in the Emergency Surgery Setting
The aim of this study is to assess whether Ventriject V02Max can provide values in a clinical setting and whether this value correlates with clinical outcome in patients admitted to the emergency general surgery department in a…
- Trial name
- LESS (NCT06189131)
- Testing
- Ventriject
- Where
- United Kingdom
- Volunteers
- 68 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Microcirculatory Diffusion, Microcirculatory Convection Capacity
Association of Microcirculation, Vexus Score and Femoral Vein Doppler in Patients on the ICU After Non-emergency Cardiac Surgery
The aim of the VeMic study is to explore if venous congestion is linked with microcirculatory impairment in elective cardiac surgery patients in the postoperative ICU stay.
- Conditions
- Microcirculatory Diffusion, Microcirculatory Convection Capacity, Venous Congestion, Postoperative Cardiac Surgery
- Trial name
- VeMic (NCT07052461)
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University Hospital, Basel, Switzerland
Abdomen, Acute
Clinical Outcomes and Equality in Healthcare for Emergency General Surgery Patients Undergoing Emergency Laparotomy
The goal of this observational cohort study is to evaluate the standard of care for general surgerical patients undergoing emergency laparotomy and assess factors affecting clinical outcomes, as well as evaluating the quality of…
- Trial name
- LAPTOP (NCT05623176)
- Testing
- Standardised laparotomy care
- Where
- Sweden
- Volunteers
- 2,000 people
- Sponsor
- Region Stockholm
Postoperative Complication, Respiratory Complications
Real-time Evaluation and Continuous Observation of Vital Signs for Enhanced Recovery: a Study for the Early Identification of Complications in the Surgical Ward Following Surgery in Patients Not Eligible for Intensive Care Admission.
This study aims to evaluate whether continuous vital sign monitoring with wearable devices can help detect postoperative complications in surgical ward earlier than standard hospital monitoring.
- Conditions
- Postoperative Complication, Respiratory Complications, Cardiac Complications
- Trial name
- RECOVER (NCT07729891)
- Testing
- Continuous vital sign monitoring with Portrait Mobile in surgical ward
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Left-sided Prosthetic Heart Valve Thrombosis
Surgery Versus Fibrinolytic Therapy for Left-sided Prosthetic Heart Valve Thrombosis
Malfunction of mechanical heart valves due to clot formation is a potentially devastating complication. It often results in heart failure, death or stroke.
- Trial name
- SAFE-PVT (NCT01641549)
- Testing
- Emergency surgery, Fibrinolytic therapy
- Where
- India
- Volunteers
- 115 people
- Sponsor
- All India Institute of Medical Sciences
Hemorrhagic Shock, Blood Coagulation Disorders
Study Using Plasma for Patients Requiring Emergency Surgery
Information on the management of casualties from the ongoing conflicts in Afghanistan and Iraq has brought in to question the traditional approach to blood transfusion in hemorrhaging patients.
- Conditions
- Hemorrhagic Shock, Blood Coagulation Disorders, Blood Products, Trauma
- Trial name
- SUPPRES (NCT01221389)
- Testing
- Human Plasma
- Where
- Canada
- Sponsor
- Ottawa Hospital Research Institute
Surgery
Evaluation of the Use of the RELAX® Glasses on the Anxiety of Patients Undergoing Emergency Hand Surgery Under Locoregional Anesthesia
More than 90% of hand surgery is performed under local anesthesia and can be a source of anxiety, especially in an emergency context. The management of this intraoperative anxiety is essential for the comfort.
- Trial name
- RELAX (NCT06436118)
- Testing
- RELAX® glasses
- Where
- France
- Volunteers
- 171 people
- Sponsor
- Centre Hospitalier de Valenciennes
Surgical Site Infection
Tracking Wound Infection With Smartphone Technology
This study aims to evaluate if a smartphone-delivered tool can help assess for wound infections, and if this improves access to care and results in earlier treatment. Participants will be randomised to one of two groups.
- Trial name
- TWIST (NCT02704897)
- Testing
- Wound Assessment Tool
- Where
- 2 sites in United Kingdom
- Volunteers
- 492 people
- Sponsor
- University of Edinburgh
Sepsis, Intra-Abdominal Infections
Gelaspan vs Crystalloid Therapy in Sepsis
The goal of this randomized clinical trial is to evaluate whether balanced gelatin solution is more effective and safe than balanced crystalloid solution for perioperative fluid management in adults with sepsis undergoing…
- Trial name
- SPACES (NCT07172451)
- Testing
- Balanced Gelatin Solution, Acetate Ringer's Solution
- Where
- 9 sites in China
- Volunteers
- 318 people
- Sponsor
- Shanghai Zhongshan Hospital
Surgery
Prevent Post-discharge Hospital Admissions Using Mobile Phone App
The investigators aimed to assess the impact of a mobile phone application facilitating real-time visual and verbal communication on reducing emergency room admissions following circumcision.
- Trial name
- NCT06585956
- Testing
- Comminication via Telemedicine, Information
- Where
- Turkey (Türkiye)
- Volunteers
- 184 people
- Sponsor
- Cumhuriyet University Hospital
Emergency Laparotomy, Intestinal Obstruction
Enhanced Recovery Versus Standard Care After Emergency Abdominal Surgery in Patients Requiring Emergency Laparotomy
This study aims to compare an Enhanced Recovery After Surgery (ERAS) protocol with conventional postoperative care in adults undergoing emergency laparotomy for intestinal obstruction or intestinal perforation.
- Conditions
- Emergency Laparotomy, Intestinal Obstruction, Intestinal Perforation, Enhanced Recovery After Surgery (ERAS) Protocol
- Trial name
- NCT07650461
- Testing
- Enhanced Recovery After Surgery, Conventional Postoperative Care
- Where
- Pakistan
- Volunteers
- 102 people
- Sponsor
- Recep Tayyip Erdogan Hospital Pakistan - Muzaffargarh
Emergency Surgery
Preoperative Rapid Pou Ultrasound Assessment in Critically Ill Patients Undergoing Emergency Surgery
With the development of society, the number of emergency critical operations is increasing year by year. Traditionally, the patient's systemic and circulatory status is indirectly assessed by testing and blood pressure heart…
- Trial name
- NCT04111783
- Testing
- POU protocol ultrasound
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shenzhen People's Hospital
Emergency General Surgery Laparotomy
Surgical Apgar Score for Identifying Patients Who May Need Intensive Care After Emergency Abdominal Surgery
This prospective observational study will evaluate whether the Surgical Apgar Score can help identify patients who require direct admission to the intensive care unit after emergency abdominal surgery.
- Trial name
- SAS-ICU (NCT07814131)
- Where
- Pakistan
- Volunteers
- 77 people
- Sponsor
- King Edward Medical University