Clinical trials: Emotional Processing
Psychopathy
Effects of Transcranial Magnetic Stimulation on Social Cognition, Cognitive Processing, and Functional Brain Architecture
This clinical trial will examine whether transcranial magnetic stimulation (TMS), a noninvasive form of brain stimulation, can influence social cognition, cognitive processing, and brain function in adults with elevated…
- Trial name
- NCT07635940
- Testing
- continuous theta burst stimulation (cTBS), Intermittent theta burst stimulation (iTBS)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Healthy
Oral Oxytocin Modulation of Responses to Emotional Stimuli
The main aim of the study is to investigate whether orally administered oxytocin (24IU) can modulate neural and behavioral responses to positive and negative valence stimuli during basal (emotional scenes) and higher order…
- Trial name
- NCT04320706
- Testing
- Oral Oxytocin
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Posttraumatic Stress Disorder, Depression
Loving-Kindness Meditation for PTSD
This randomized controlled trial will assess whether a novel complementary and alternative medicines (CAM) intervention, Loving-kindness Meditation (LKM), is not meaningfully inferior to another group-based PTSD treatment …
- Trial name
- NCT01962714
- Testing
- Loving-Kindness Meditation, Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- VA Office of Research and Development
Positive Expectations
Positive Expectation Effects on Early Emotional Processing
Insights into the mechanisms of expectation effects in the emotional domain can be invaluable for the development of potential therapeutic interventions for mood disorders.
- Trial name
- NCT07615530
- Testing
- Saline Nasal Spray
- Where
- Germany
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Depression, History of Suicide Attempt
Behavioral Adaptation to Negative Social Cues in Depressed Patients According to Personal History of Suicide Attempt- COMPASS
Social interactions are part of daily life. To decide to interact with someone or not is a routine for humans. To ensure the quality of interpersonal relationships, emotional cues must be taken into account to adapt optimally the…
- Trial name
- COMPASS (NCT03898648)
- Testing
- Waiting room task
- Where
- France
- Volunteers
- 66 people
- Sponsor
- University Hospital, Montpellier
Mild-to-Moderate Stress
Prebiotic Effects on Anxiety, Cortisol, and Emotional Processing in Mild-to-Moderately Stressed Adults
The levels of stress that we experience as a population are continuing to rise due to financial, social and work pressures, particularly in mid-life where additional factors such as family and career often compound these issues.
- Trial name
- PEACE (NCT06991023)
- Testing
- Prebiotic (Bimuno®)
- Where
- United Kingdom
- Volunteers
- 55 people
- Sponsor
- University of Reading
Anhedonia, Cognitive Function
Pitolisant Effects on Affect and Cognition Exploratory Study (PEACE Study)
The goal of this study is to investigate the effects of selective histamine 3 antagonist pitolisant on brain function and cognition in healthy individuals. The main questions it aims to answer are: 1.
- Trial name
- PEACE (NCT05849675)
- Testing
- Pitolisant 17.8 MG [Wakix]
- Where
- United Kingdom
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Emotional Processing
Losartan and Emotional Learning
This study explores the effects of single-dose losartan (50mg) versus placebo on emotional processing in healthy volunteers.
- Trial name
- NCT06628154
- Testing
- Losartan potassium 50mg
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Cannabis Use Disorder, Severe
Cannabis and Processing Emotions Study
The goal of this study is to test a causal neural mechanism of cannabis use-related problem recognition in individuals with severe cannabis use disorder using a non-invasive form of neuromodulation called transcranial magnetic…
- Trial name
- CAPE (NCT06907979)
- Testing
- TMS - Active iTBS, TMS - Active cTBS
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Auburn University
Healthy Males
Oxytocin and Emotion Processing
The purpose of this study is to determine whether oxytocin influences emotional processing and learning of emotional and social stimuli.
- Trial name
- NCT02156661
- Testing
- Oxytocin
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn
Healthy
Can Mimic Emotional Expression Training Help Improve Emotion Processing
The main aim of the present study is to investigate whether mimicking emotional expressions training via FaceReader software can improve emotional processing and recognition in healthy subjects, especially individuals with hityer…
- Trial name
- NCT04922684
- Testing
- Mimic facial expressions
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Antidepressive Agents, Second-Generation
Antidepressants, Emotions and Personality
Neuroticism is a personality trait described as an enduring tendency to experience negative emotional states and to respond poorly to environmental stress.
- Trial name
- NCT01946607
- Testing
- Citalopram
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Social Anxiety Disorder
Positive Emotional Processing: Exploring Novel Treatment Targets in Social Phobia
The purpose of this study is to test the effects of a computerized approach/avoidance training (AAT) procedure in a sample of individuals diagnosed with social anxiety disorder (SAD).
- Trial name
- NCT02136212
- Testing
- Approach-positive AAT, Control AAT
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Traumatic Grief, Post Traumatic Stress Disorder PTSD
EMDR Grief Protocol for Traumatic Grief After Earthquake-Related Loss
This pilot randomized controlled study evaluated the effectiveness of the EMDR Grief Protocol in adults who experienced the loss of a loved one in the February 6, 2023 Kahramanmaraş earthquakes.
- Conditions
- Traumatic Grief, Post Traumatic Stress Disorder PTSD, Emotional Processing
- Trial name
- NCT07776769
- Testing
- EMDR Grief Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Istanbul Bilgi University
Healhty
Oromucosal Oxytocin and Vasopressin Modulation of Emotional Face Attention
The goal of this clinical trial is to learn how 24 IU oxytocin (OT) and 24 IU arginine vasopressin (AVP), administered through the oral mucosa, affect attention to emotional faces and related brain activity in healthy adults.
- Trial name
- NCT07838493
- Testing
- Oxytocin (OT), Arginine Vasopressin (AVP)
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Emotional Processing and Cognitive Function in Perimenopausal Women Experiencing Cognitive Perturbations, Perimenopause
Probiotic Intake and Perimenopausal Psychological Assessments
Recent evidence suggests multi-strain probiotics containing Lactobacillus rhamnosus and Bifidobacterium longum have been found to enhance emotional processing and reduce salience to negative cues in studies involving people with…
- Conditions
- Emotional Processing and Cognitive Function in Perimenopausal Women Experiencing Cognitive Perturbations, Perimenopause, Perimenopause-Related Depression, Perimenopausal Women
- Trial name
- PIPPA (NCT07590999)
- Testing
- Multi-strain probiotic
- Where
- United Kingdom
- Volunteers
- 106 people
- Sponsor
- University of Oxford
Depression, Inflammation
Simvastatin and Emotional Processing (OxSTEP)
Simvastatin is being employed because it is a 'statin'. As a drug class, statins have broad anti-inflammatory properties. Low-level inflammation is thought to be a potentially important mediator of the effects of psychosocial…
- Trial name
- OxSTEP (NCT04973800)
- Testing
- Simvastatin 20mg
- Where
- United Kingdom
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Healthy
Role of Dopamine, Serotonin and 5-HT2A Receptors in Emotion Processing
The study will test the effect of dopamine, serotonin, and direct 5-HT2A receptor stimulation on empathy, mood perception, and amygdala activity to fearful stimuli.
- Trial name
- LAM (NCT03019822)
- Testing
- LSD, MDMA, Amphetamine
- Where
- Switzerland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Breast Cancer Female, Depressive Symptoms
The Role of Emotional Processing in Improving the Quality of Life of Breast Cancer Patients
The purpose of this study is to examine two mechanistic changes: emotion processing (awareness, expression and acceptance) and cholinergic anti-inflammatory processes (HRV and cytokine expression) through which an Art Therapy…
- Conditions
- Breast Cancer Female, Depressive Symptoms, Fatigue, Pain
- Trial name
- REPAT (NCT03377816)
- Testing
- Art Therapy
- Where
- Israel
- Volunteers
- 318 people
- Sponsor
- University of Haifa
Emotions
Effects of Propranolol (vs. Placebo) on Information Processing During Presentation of Emotionally Arousing Pictures
The main objective of the present study is to combine two lines of research, investigating the interaction between emotional processing and memory performance (on both behavioral and electrophysiological levels) and its…
- Trial name
- BBEmoMem_G (NCT02509559)
- Testing
- propranololhydrochloride, Net Station® System and compatible Geodesic Sensor Nets®, VITAPORT
- Where
- Germany
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald