Clinical trials: Enamel Demineralization
White Spot Lesion of Tooth, Orthodontic Treatment
S-PRG Filler for Preventing White Spot Lesions During Orthodontic Treatment
White spot lesions are early areas of enamel demineralization that may develop during orthodontic treatment with fixed braces. This study aims to evaluate the effectiveness of S-PRG Barrier Coat in preventing white spot lesions…
- Conditions
- White Spot Lesion of Tooth, Orthodontic Treatment, Enamel Demineralization, Fluoride Varnishes
- Trial name
- SPRG-WSL (NCT07839780)
- Testing
- S-PRG Barrier Coat, S-PRG Barrier Coat + 5% Sodium Fluoride Varnish, 5% sodium fluoride varnish
- Where
- Malaysia
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Enamel Demineralization
Comparative Assessment of Adhesive PreCoated (APC) Flash-free and Conventional Brackets and the Effects on Enamel Demineralization and Periodontal Health
Adhesive PreCoated (APC) flash-free brackets have been recently introduced, with no need of flash removal step. Evaluation of APC and conventional brackets and their effects on enamel demineralization and periodontal health.
- Trial name
- NCT07752290
- Testing
- Group A, Group B
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Enamel Demineralization, White Spot Lesions
Silver Nanoparticle-Coated Orthodontic Brackets for Preventing Enamel Demineralization
The goal of this clinical trial is to learn whether orthodontic brackets coated with silver nanoparticles can help prevent early damage to tooth enamel in people receiving fixed braces.
- Trial name
- AgBracket (NCT07707336)
- Testing
- Silver Nanoparticle-Coated Stainless Steel Orthodontic Brackets, Conventional Stainless Steel Orthodontic Brackets
- Where
- United Arab Emirates
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ajman University
White Spot Lesions, Enamel Demineralization
A Novel Remineralizing Self-Etch Primer for Orthodontic Bracket Bonding
This randomized clinical trial aims to evaluate the clinical effectiveness of a remineralizing self-etch primer used for orthodontic bracket bonding.
- Trial name
- NCT07291830
- Testing
- Remineralizing self-etch primer (M-SEP, SEP 1), Standard self-etch primer (P-SEP, SEP 2)
- Where
- Iraq
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Dental Caries, Tooth Demineralization
Kissing as a Protective Factor Against Acidic pH in Saliva
The pH of saliva can be acidic or alkaline; When it is acidic, the tooth enamel is demineralized, that is, weakened. Additionally, bacteria in the mouth can increase and cause infections such as cavities.
- Conditions
- Dental Caries, Tooth Demineralization, Teeth Erosion Limited to the Enamel
- Trial name
- NCT06501729
- Testing
- Kiss
- Where
- Ecuador
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Universidad Catolica Santiago de Guayaquil
Demineralization, Remineralization
Clinical Study to Evaluate the Anti-cavity Efficacy of Three Dentifrices: An In Situ Model
Clinical study to evaluate the anti-cavity effectiveness of three dentrifices using an intra-oral enamel Demineralization and Remineralization In-Situ Model.
- Conditions
- Demineralization, Remineralization, Dental Cavity, Enamel Lesions
- Trial name
- NCT07134231
- Testing
- Fluoride free toothpaste in a chalk base, Fluoride Toothpaste, Fluoride free toothpaste in a PCC/RNCC base
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Enamel Lesions, Demineralization, Tooth
Evaluation of the Anti-cavity Efficacy of Three Dentifrices Using an Intra-oral Enamel Demineralization - Remineralization In-Situ Model
Clinical study to evaluate the anti-cavity efficacy of three dentifrices using an intra-oral enamel Demineralization - Remineralization In-Situ Model. This is a Phase III, single-center, triple-blind with a crossover design.
- Conditions
- Enamel Lesions, Demineralization, Tooth, Remineralization, Dental Cavity
- Trial name
- REPAIR (NCT06732518)
- Testing
- Fluoride Toothpaste, Fluoride free toothpaste in a chalk base, Fluoride free toothpaste in a PCC/RNCC base
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dental Caries, Hydroxyapatite
Caries-preventing Effect of a Hydroxyapatite-toothpaste in Adults
Target question is as the following one: Does the daily use of a fluoride-free, microcrystalline hydroxyap-atite (HAP) - containing test toothpaste have a non-inferior caries preventing effect in the permanent dentition compared…
- Conditions
- Dental Caries, Hydroxyapatite, Tooth Decay, Dentin, Carious
- Trial name
- CA1 (NCT04756557)
- Testing
- Experimental., Active comparator
- Where
- Poland
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Dental Caries on Smooth Surface Limited to Enamel, Tooth Demineralization
Resin Infiltration and Fluoride Varnish Lesion Arresting Efficacy on Non-cavitated Proximal Lesion
Protection of dental hard tissues is one of the most important points of cariology. For this purpose, oral hygiene training (effective brushing and motivation), non-invasive approaches such as flouride varnish applications and…
- Conditions
- Dental Caries on Smooth Surface Limited to Enamel, Tooth Demineralization, Dental Caries, Dentistry, Operative
- Trial name
- NCT05202665
- Testing
- ICON DMG Resin Infiltration (micro-invasive approach), ClinproTM White Varnish, 3M ESPE Fluoride Varnish (non-invasive approach)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ege University