Clinical trials: End Stage Renal Disease
Kidney Failure, Chronic, Neuromuscular Blockade
Efficacy and Safety of Sugammadex in Renal Diseased Patients
The purpose of this study is to determine whether sugammadex reverses a profound neuromuscular blockade induced by rocuronium in patients with end-stage renal disease just as effectively and safely as it does in patients with…
- Trial name
- NCT01785758
- Testing
- Sugammadex (4 mg/Kg)
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of São Paulo
End Stage Renal Disease (ESRD), Brachiocephalic Fistula (BCF)
Outcome of BCF Access in Hemodialysis Patients
Dialysis access, which is the connection that allows blood to flow in and out of the body during dialysis sessions, is important to remove wastes and excess fluid for patients with end stage renal disease (ESRD).
- Conditions
- End Stage Renal Disease (ESRD), Brachiocephalic Fistula (BCF), Cephalic Arch Stenosis (CAS), Dialysis
- Trial name
- BCF (NCT01693263)
- Testing
- brachiocephalic fistula (BCF)
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Chicago
End-stage Renal Disease, Cardiorenal Syndrome
Cardiorenal Syndrome in End-Stage Kidney Disease
Cardiorenal Syndrome (CRS) is prevalent among end-stage renal disease (ESRD) patients. Recently, its prevalence is rising. There are several different clinical presentations of this syndrome.
- Conditions
- End-stage Renal Disease, Cardiorenal Syndrome, Heart Disease
- Trial name
- NCT02238093
- Where
- Israel
- Volunteers
- 270 people
- Sponsor
- Hillel Yaffe Medical Center
Kidney Transplantation
Study in End-stage Renal Disease Patients Awaiting Kidney Transplant to Investigate the Potential Effect of IVIG Treatment on the Pharmacokinetics and Pharmacodynamics of LFG316
Investigate whether concomitant treatment with intravenous immunoglobulin (IVIG) can alter the pharmacokinetics and pharmacodynamics of LFG316 to an extent which would necessitate dose adaptation for LFG316 in pre-sensitized…
- Trial name
- NCT02878616
- Testing
- LFG316, IVIG
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Novartis Pharmaceuticals
Pediatric End Stage Renal Disease, Hemodialysis
More Frequent In-Center Hemodialysis in Pediatric End Stage Renal Disease
A health kidney works 24 hours a day, 7 days a week to remove toxins and fluid from the body. Many children with permanent kidney failure undergo dialysis, a life saving procedure that takes the place of a kidney.
- Trial name
- NCT01352455
- Testing
- Hemodialysis
- Where
- 3 sites in United States, Canada
- Volunteers
- 7 people
- Sponsor
- Children's Hospital of Philadelphia
Bladder Cancer, Prostate Cancer
Medtronic Hugo™ Robotic Assisted Surgery (RAS) System in Urologic Surgery (Expand URO)
This study will evaluate the safety and performance of the Medtronic Hugo™ RAS System when used for urologic RAS procedures.
- Conditions
- Bladder Cancer, Prostate Cancer, Kidney Cancer, Pelvic Tumor
- Trial name
- NCT05696444
- Testing
- RAS Prostatectomy, RAS Cystectomy, RAS Nephrectomy
- Where
- 6 sites in United States
- Volunteers
- 144 people
- Sponsor
- Medtronic - MITG
Chronic Kidney Disease, Anemia
Conversion Study From Epoetin Alfa to Monthly Peginesatide Injection in Patients With Chronic Kidney Disease on Dialysis
The purpose of this study is to understand the effects of a dialysis center switching its dialysis patients from using Epoetin alfa to peginesatide injection on hemoglobin levels and other parameters.
- Trial name
- DIAMOND (NCT01478971)
- Testing
- Epoetin, Peginesatide
- Where
- 5 sites in United States
- Volunteers
- 184 people
- Sponsor
- Takeda
End Stage Kidney Disease
Evaluation of a Website on Living Kidney Donation for Hispanics
The purpose of this study is to increase understanding about living kidney donation (LKD) among Hispanic/Latino patients and public by increasing knowledge and positive attitudes about LKD.
- Trial name
- NCT01859871
- Testing
- Website Intervention
- Where
- 2 sites in United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Renal Dialysis, Health Literacy Level
Impact of Hospital Pharmacist Intervention on Medication Management in Dialysis Patients
The goal of this clinical trial is to learn if an intervention of a hospital pharmacist could help, dialysis patients managed his treatment. In a first time, the health literacy level will be assed.
- Conditions
- Renal Dialysis, Health Literacy Level, Kidney Disease, Chronic
- Trial name
- IPhaDia (NCT06692231)
- Testing
- Pharmacist intervention
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Hospitalier de Vichy
End Stage Renal Disease, Renal Impairment
A Study of Belzutifan (MK-6482) in Participants With Renal Impairment (MK-6482-021)
The primary purpose of this study is to compare the plasma pharmacokinetics (PK) of belzutifan (MK-6482) following a single oral 120 mg dose in participants with end stage renal disease (ESRD) before and after hemodialysis (HD)…
- Trial name
- NCT04994522
- Testing
- Belzutifan
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Hyperphosphatemia
The Effect of Oral Niacinamide on Serum Phosphorus Levels in Hemodialysis Patients
Elevated phosphorus levels are a common problem in dialysis patients. However, it is associated with an increase in death and hospitalizations.
- Trial name
- NCT00316472
- Testing
- Niacinamide
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Washington University School of Medicine
Kidney Transplantation, End Stage Kidney Disease (ESRD)
Novel Desensitization Kidney Transplantation
This proposal's objective is to determine whether belatacept, in conjunction with a proteasome inhibitor can be used to safely increase the likelihood of finding an acceptable donor for highly HLA sensitized kidney transplant…
- Trial name
- NCT05345717
- Testing
- Belatacept Injection
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Chicago
End Stage Renal Disease
The Impact of Mindfulness-Based Intervention on Psychophysical Health
Background: Hemodialysis is considered as an effective therapy to remove harmful wastes from the body and to improve the quality of life in patients suffering from end-stage renal disease (ESRD).
- Trial name
- NCT06064708
- Testing
- Mindfulness-based intervention
- Where
- 2 sites in Jordan
- Volunteers
- 64 people
- Sponsor
- Jordan University of Science and Technology
End-Stage Renal Disease
Role of Extrarenal 1-Alpha-Hydroxylase in Patients With End Stage Renal Disease
The goal of this study is to evaluate the role of nutritional Vitamin D deficiency as a potential contributor to the morbidity witnessed in patients with end-stage renal disease
- Trial name
- NCT00677534
- Testing
- Cholecalciferol
- Volunteers
- 7 people
- Sponsor
- University of Kansas
End Stage Renal Failure on Dialysis, Periodontitis
Effect of Non-Surgical Periodontal Therapy on Serum Albumin Levels of Patients on Maintenance Hemodialysis Therapy,
Periodontitis is a destructive chronic infection of the gums, ligaments, and bone, predominantly caused by Gram-negative bacteria. Individuals with periodontal disease are at increased risk of systemic diseases.
- Trial name
- NCT01641757
- Testing
- non-surgical periodontal therapy
- Where
- Pakistan
- Volunteers
- 160 people
- Sponsor
- University of the Punjab
End Stage Renal Disease, Hemodialysis
L-Arginine and Spironolactone Trial in Dialysis-Dependent ESRD
Cardiovascular disease is the primary cause of death in patients with end stage renal disease (ESRD). New research suggests that the high risk of death may be partly due to high levels of fibrosis and a loss of small blood…
- Trial name
- LAST-D (NCT01855334)
- Testing
- Spironolactone, L-arginine
- Where
- 3 sites in United States
- Sponsor
- Brigham and Women's Hospital
Kidney Transplantation
Imlifidase for Highly Sensitized Kidney Transplant Recipients With a posItive crossmAtch Against a Deceased Donor: Results of Kidney Transplantations Performed in Accordance to the French Guidelines.
Imlifidase is a recombinant cysteine protease derived from Streptococcus pyogenes and produced in Escherichia coli, which has the ability to cleave and degrade all human IgGs.
- Trial name
- ISKIA (NCT07379957)
- Where
- 20 sites in France
- Volunteers
- 450 people
- Sponsor
- University Hospital, Bordeaux
Anemia Associated With End Stage Renal Disease (ESRD)
Study of Roxadustat Conversion in Participants Receiving Stable Erythropoiesis-Stimulating Agent (ESA) or as Initial Anemia Treatment in Chronic Dialysis Participants
The purpose of this study is to assess the safety and effectiveness of Roxadustat dosing regimens among chronic dialysis participants converted from ESA therapy or who are ESA-naïve.
- Trial name
- NCT04410198
- Testing
- Roxadustat
- Where
- 9 sites in United States
- Volunteers
- 203 people
- Sponsor
- Kyntra Bio
Chronic Renal Disease
Immunosenescence and Hepatitis B Virus (HBV) Vaccine Efficacy in Chronic Renal Disease Patient
The aim of this study is to investigate the role of immunosenescence in the HBV vaccination response in patients with renal insufficiency.
- Trial name
- IVVI (NCT02375711)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Chronic Renal Failure
the Effect of Calcium Dobesilate on Non Dialysis Patients With CKD
To investigate the feasibility of calcium dobesilate in the treatment of microvascular injury provides new ideas and theoretical basis for the prevention and treatment of chronic renal failure.
- Trial name
- NCT03427944
- Testing
- Calcium Dobesilate group, Conventional Treatment group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
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