Clinical trials: End-Stage Kidney Disease
End Stage Renal Disease
Conventional Hemodialysis vs. Short Daily Hemodialysis (6 Days / Week) and Mechanisms of Blood Pressure Control
More than 80% of patients with end stage renal disease have hypertension; 70% of whom are poorly controlled using conventional Hemodialysis therapy.
- Trial name
- NCT00759967
- Testing
- Microneurography, Bioimpedance testing
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Ottawa Hospital Research Institute
Chronic Kidney Disease, Chronic Renal Failure
A Phase 3 Study Comparing the Effects of Intravenous Epoetin Hospira and Epoetin Alfa [Epogen] (Amgen) in Patients With Chronic Renal Failure Requiring Hemodialysis and Receiving Epoetin Maintenance Treatment. AiME - Anemia Management With Epoetin
The purpose of this study is to demonstrate therapeutic equivalence of IV Epoetin Hospira compared to IV Epogen (Amgen), based on maintenance of Hb levels and study drug dose requirements in patients treated for anemia associated…
- Trial name
- AiME - 01 (NCT01473407)
- Testing
- Epoetin Hospira, Epogen (Amgen)
- Where
- 85 sites in United States, Puerto Rico
- Volunteers
- 612 people
- Sponsor
- Pfizer
Chronic Kidney Disease Stage 3B, Chronic Kidney Disease stage4
Physiopathology of Neuromuscular Function Related to Fatigue in Chronic Renal Disease
Chronic Kidney Disease (CKD) induces many metabolic troubles especially for the advanced CKD (stage 3b-5) patients and their prevalence and importance grow with the deterioration of the glomerular filtration rate (GFR).
- Conditions
- Chronic Kidney Disease Stage 3B, Chronic Kidney Disease stage4, Chronic Kidney Disease Stage 5, Fatigue
- Trial name
- PIONEER (NCT04330807)
- Testing
- Handgrip fatigability test, Questionnaires
- Where
- France
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier le Mans
End Stage Renal Disease, Hepatitis C
Renal Transplants in Hepatitis C Negative Recipients With Nucleic Acid Positive Donors
In this study, individuals without hepatitis C infection who are on the kidney transplant waitlist will receive a kidney from a deceased donor with hepatitis C infection and will be treated for hepatitis C at the same time.
- Trial name
- NCT03627299
- Testing
- 300mg glecaprevir/pibrentasivir 120mg
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Johns Hopkins University
Kidney Diseases, Chronic
The Effect Of Mobile Traınıng Applıcatıons On Chronıc Renal Faılure Progressıon
The purpose of research that Mobile Education Application is to evaluate its effects on the progress of chronic renal failure . The sample of the study, which is conducted with a semi-experimental design, consisted of 100…
- Trial name
- NCT05714358
- Testing
- Education
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
End Stage Renal Failure
Physical and Psychological Profiles Associated With Patient's Preference for ESRD Treatment
Highlighting the relationship between psychological and physical profiles and patient's preference to better understand the patient's treatment preference and improve the information provided.
- Trial name
- NCT01834755
- Testing
- Evaluation of psychological phenotype
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
End Stage Renal Disease
Efficacy Study of Zinc Supplementation on Anemia, Oxidative Stress and Inflammation in Hemodialysis Patients
The purpose of the study is to evaluate the effect of Zinc supplementation on health status of hemodialysis patients through measurement of the following before and after Zinc administration: Inflammatory markers, Oxidative…
- Trial name
- NCT02335593
- Testing
- Zinc Sulphate, Corn Starch filled Hard Gel Capsules, Epoetin alfa 2000-4000 IU solution for injection
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Ain Shams University
End Stage Renal Disease
Intravenous Immune Globulin (IVIG) Treatment Protocol in Kidney Transplant Patients
The purpose of this study is to test the clinical and laboratory observations of IVIG therapy in the highly sensitized patient. We will study the effects of patients treated with IVIG or Cytogam in combination with plasmaphoresis…
- Trial name
- NCT00586716
- Testing
- intravenous immune globulin
- Volunteers
- 22 people
- Sponsor
- Loma Linda University
Chronic Kidney Failure, Prostatic Hyperplasia
The Effect of Daily Tamsulosin 0.2mg Administration on Renal Function in Patients With Benign Prostatic Hyperplasia
The purpose of this study is to determine whether medical treatment for bladder outlet obstruction is effective in improvement of glomerular filtration rate and/or proteinuria.
- Trial name
- NCT02033798
- Testing
- Tamsulosin
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- The Catholic University of Korea
Pure Red-Cell Aplasia, Chronic Kidney Failure
Surveillance Study to Estimate the Incidence of Pure Red Blood Cell Aplasia Among Patients With Chronic Kidney Failure
The purpose of this study is to estimate the incidence rate of pure red cell aplasia (PRCA; aplastic anemia) mediated by erythropoietin (EPO) antibodies in patients who are receiving subcutaneous (s.c.) epoetin alfa (polysorbate…
- Trial name
- PRIMS (NCT00391287)
- Where
- 387 sites in Australia, Belgium and 13 more
- Volunteers
- 15,334 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
End-stage Renal Disease
The Effect of the Incretin Hormones on the Endocrine Pancreatic Function During Hyperglycemia in End-stage Renal Disease
Patients with end-stage renal disease (ESRD) have a high prevalence of impaired glucose metabolism. The pathophysiological cause is uncertain, but disturbances in the secretion, elimination and effect of glucagon, insulin and the…
- Trial name
- NCT02237521
- Testing
- Eu- and hyperglycemic clamp, Arginine test
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bo Feldt-Rasmussen
End Stage Renal Disease
Study to Investigate the Pharmacokinetic Comparability of Dosing Triferic AVNU IV by Continuous Infusion and IV Bolus.
This study will investigate the administration of Triferic AVNU intravenously by three different administration schedules compared to continuous infusion over 3 hours
- Trial name
- NCT04409132
- Testing
- Triferic
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Rockwell Medical Technologies, Inc.
End Stage Renal Failure
Volume,Sodium and Blood Pressure Management in HD
The purpose of this study to conduct a pilot, randomized trial in stable HD patients to evaluate the effect of gradual, step-wise reduction of post-hemodialysis target weight, combined with diligent dietary sodium restriction and…
- Trial name
- VSBP (NCT01766882)
- Testing
- Lower sodium intervention, Progressive Challenge to Post Dialysis Weight
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan
Chronic Renal Failure
Clinical Study on Optimised Removal of Protein-bound Uremic Toxins With Convective Dialysis Treatment.
Patients will be treated with hemodiafiltration (HDF) in postdilution mode, as a control therapy, during 9 weeks. During week 5 the 1st intervention treatment, predilution hemofiltration (HF) or predilution HDF, will be performed…
- Trial name
- NCT00337831
- Testing
- Performance of predilution hemofiltration, predilution hemodiafiltration or postdilution hemodiafiltration
- Where
- Belgium
- Volunteers
- 17 people
- Sponsor
- University Hospital, Ghent
Kidney Failure, Chronic
Autonomic Nervous System Dysfunction in Patients With End-stage Kidney Disease
The prevalence of autonomic nervous system (ANS) dysfunction in patients with end-stage kidney disease (ESKD) is considered to be increased.
- Trial name
- NCT05278702
- Where
- Greece
- Volunteers
- 78 people
- Sponsor
- Aristotle University Of Thessaloniki
End Stage Renal Disease
CellCept/Iron Study: The Iron Ion-Mycophenolate Mofetil Chelation Complex Interaction in Renal Allograft Recipients
The objective of this study is to determine the extent and magnitude of the pharmacokinetic drug interaction between mycophenolate mofetil (MFF) (under Css conditions) in the presence of iron in renal transplant recipients.
- Trial name
- NCT00227045
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Michigan
End Stage Renal Disease
Research Study Evaluating Cinacalcet for Patients With End Stage Renal Disease (ESRD)
The purpose of this study is to observe the effects of a treatment strategy that incorporates cinacalcet HCl into the management of secondary hyperparathyroidism (HPT) in subjects with ESRD receiving hemodialysis, on bio-intact…
- Trial name
- NCT00113945
- Testing
- Cinacalcet
- Volunteers
- 360 people
- Sponsor
- Amgen
Renal Impairment
Study of GBT021601 in Participants With Renal Impairment
Renal Impairment study of GBT021601.
- Trial name
- NCT05878704
- Testing
- GBT021601
- Where
- 4 sites in United States
- Volunteers
- 8 people
- Sponsor
- Pfizer
End-Stage Renal Disease (ESRD)
A Clinical Trial of Epizon-701 (EPN-701) in Subjects With End-Stage Renal Disease (ESRD)
Patients with End Stage Renal Disease (ESRD) are prone to early and accelerated vascular calcification. Both the prevalence and extent of the vascular calcification are predictive for cardiovascular morbidity and all-cause…
- Trial name
- NCT05285787
- Testing
- EPN-701 (Oral)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Epizon Pharma, Inc.
End-Stage Renal Disease
Cuffless BP Monitoring in Hemodialysis
This is a prospective, multicenter observational cohort study designed to evaluate the validity and clinical utility of cuffless blood pressure monitoring using the CART BP Pro device in patients receiving maintenance…
- Trial name
- NCT07753876
- Testing
- CART BP Pro
- Where
- South Korea
- Volunteers
- 240 people
- Sponsor
- Gangnam Severance Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.