Clinical trials: Endobronchial Metastases
Lung Cancer
Utility of Endobronchial Ultrasound Guided Needle Biopsy in Early Stage Non- Small Cell Lung Cancer (NSCLC)
The goal of this clinical research study is to learn how accurately an endobronchial ultrasound transbronchial needle aspiration (EBUS -TBNA) may detect mediastinal lymph node metastases in patients with clinical stage I and II…
- Trial name
- NCT00832715
- Testing
- EBUS-TBNA
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- M.D. Anderson Cancer Center
Lung Non-Small Cell Carcinoma, Mediastinal Neoplasm
Phase II Trial of Lung Chemoemobolization
This phase II trial evaluates how well transarterial chemoembolization (TACE) works for treating patients with non-small cell lung cancer or lung metastases.
- Conditions
- Lung Non-Small Cell Carcinoma, Mediastinal Neoplasm, Pleural Neoplasm, Lung Metastases From Any Primary
- Trial name
- NCT05672108
- Testing
- Computed Tomography, Ethiodized Oil, Mitomycin
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- City of Hope Medical Center
Non Small Cell Lung Cancer
Risk Factors of Medistinal Metastasis in Endoscopic Staging of Lung Cancer
The purpose of this study is to investigate risk factors for mediastinal lymph node metastasis in potentially operable non-small cell lung cancer in order to find indications for endoscopic mediastinal staging.
- Trial name
- NCT02991924
- Where
- South Korea
- Volunteers
- 600 people
- Sponsor
- National Cancer Center, Korea
COPD
Trial Evaluating the Rate of Pneumothorax in Severe Emphysema Secondary to Endoscopic Volume Reduction With Two-stage ZEPHYR® Valves Versus Endoscopic Volume Reduction With One-stage ZEPHYR® Valves
Chronic obstructive pulmonary disease (COPD) affects 3.5 million people and is the third leading cause of death worldwide. Emphysema involves air retention in the lungs and is ultimately responsible for a major deterioration in…
- Trial name
- REPEAT (NCT06181357)
- Testing
- Endoscopic lung volume reduction in 2 stages, Endoscopic lung volume reduction in 1 stage
- Where
- 17 sites in France
- Volunteers
- 244 people
- Sponsor
- University Hospital, Limoges
Lung Cancer
Comparison of 22-gauge and 19-gauge Aspiration Needle During EBUS-TBNA
Investigators intend to compare the 19-gauge needle and the 22-gauge-needle during EBUS-TBNA concerning the diagnostic yield, the quality and quantity of each biopsy needle without raising the rate of complications.
- Trial name
- NCT02813603
- Testing
- EBUS
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 100 people
- Sponsor
- University Hospital, Essen
Lung Cancer (Locally Advanced or Metastatic)
Evaluation of Endobronchial Ultrasound Needle Cleaning Techniques and Their Impact on Specimen Contamination
Endobronchial ultrasound (EBUS) bronchoscopy is commonly used to sample lymph nodes in patients with suspected or known lung cancer to determine the stage of the disease.
- Trial name
- EBUS (NCT07461662)
- Testing
- Purge cleaning
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- University of Mississippi Medical Center
Lung Cancer, Lung Cancer Metastatic
ANET Electrosurgery Applicator Pilot Evaluation Study
Evaluate the preliminary safety and performance of the Electrosurgery Applicator (ANET device) during and after bronchoscopic ablation of a target pulmonary nodule/tumor.
- Trial name
- NCT03400748
- Testing
- RF Ablation
- Where
- 4 sites in United States, Canada
- Volunteers
- 6 people
- Sponsor
- Olympus Corporation of the Americas
Endobronchial Metastases, Bronchoesophageal Fistula
Clinical Application Value of Remazolam Combined With Sugammadex Sodium in Anesthesia for Endotracheal Surgery Under Bronchoscopy
This study is a prospective, randomized, controlled trial. In this study, 30 patients who underwent endotracheal tumor resection under rigid bronchoscope or stent placement for acquired tracheoesophageal fistula were selected as…
- Conditions
- Endobronchial Metastases, Bronchoesophageal Fistula, General Anesthetic Drug Adverse Reaction
- Trial name
- NCT05468671
- Testing
- Remimazolam, Propofol, Rocuronium
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Zhejiang Cancer Hospital
Lung Metastases, Endobronchial Metastases
Chemoembolization for Lung Tumors
This study is being done to determine if it is safe to perform lung chemoembolization and if the lung chemoembolization procedure can successfully deliver chemotherapy to lung tumors.
- Conditions
- Lung Metastases, Endobronchial Metastases, Pleural Metastases, Mediastinal Metastases
- Trial name
- NCT04200417
- Testing
- Chemoembolization, Mitomycin C, Lipiodol
- Where
- 4 sites in United States
- Volunteers
- 10 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Lung Cancer, Non Small Cell Lung Cancer
Optimizing Endobronchial Ultrasound Sampling for Molecular Markers for NSCLC
In this monocentric randomized controlled trial, 120 potential non small cell lung cancer (NSCLC) patients for which tissue diagnosis and material for next generation sequencing (NGS) is required for clinical management will be…
- Conditions
- Lung Cancer, Non Small Cell Lung Cancer, Circulating Tumor Cell
- Trial name
- OPTIMAL (NCT05560776)
- Testing
- Endobronchial ultrasound
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
Non Small Cell Lung Cancer
Study Comparing EBUS & EUS to Mediastinoscopy in Staging and Detection of Lung Cancer
This is a prospective randomized clinical trial with the study cohort comprised of all male and female patients over the age of 21 presenting to the study site for evaluation of lung cancer.
- Trial name
- NCT00970645
- Testing
- Mediastinoscopy/thoracoscopy, EBUS/EUS
- Where
- 3 sites in United States
- Volunteers
- 2 people
- Sponsor
- Mayo Clinic
Lung Cancer
Surgical Versus Non-surgical Staging of Lung Cancer
About half of all lung cancers are caught after they have spread to nearby lymph nodes. Lymph nodes are small glands found throughout the body that remove bacteria and foreign particles (part of the immune system).
- Trial name
- NCT01117714
- Testing
- Integrated Staging for Early Detection of Metastases in Lung Cancer
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- Medical University of South Carolina