Clinical trials: Endocrine, Nutritional, Metabolic and Immunity Disorders
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
User Experience With DuraTouch® in Patients With Type 1 or Type 2 Diabetes
This study looks at overall impact of the use of DuraTouch® in terms of ease, convenience to use and satisfaction in participants with either type 1 or type 2 diabetes.The study will last for about 12 weeks.
- Trial name
- NCT07052292
- Testing
- DuraTouch®
- Where
- 11 sites in Poland
- Volunteers
- 128 people
- Sponsor
- Novo Nordisk A/S
Type 1 Diabetes Mellitus, Glycemic Control
Effect of Immediate Hemoglobin A1c on Glycemic Control in Children With Type I Diabetes Mellitus
Immediate feedback of hemoglobin A1c (A1c) results to adults with type 1 and 2 diabetes allows more appropriate care decisions at the clinic visit and may improve glycemic control.
- Trial name
- NCT00898534
- Testing
- Bayer DCA2000+ Hemoglobin A1c analyzer
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- Boston Children's Hospital
Diabetes Mellitus, Type 1
Effect of HCL Insulin Delivery System on Glycemic Control in Patients With T1D
The goal of this study is compare the effect of hybrid closed loop system (HCL) for automatic insulin dosing treatment on the glycemic control of type 1 diabetes (T1D) in patient with different initial glycated hemoglobin.
- Trial name
- NCT05924932
- Testing
- Tandem t:slim X2 with hybrid closed loop system Control IQ, glucose sensor: Dexcom G6, MiniMed 780G, with hybrid closed loop system SmartGuard, sensor Guardien 4
- Where
- Czechia
- Volunteers
- 120 people
- Sponsor
- Masaryk Hospital Usti nad Labem
Type 1 Diabetes
Prevalence of Post Traumatic Stress Disorder Related to Diabetes Diagnosis or Severe Hypoglycaemia in Adult With Type 1 Diabetes
In France, the adult population living with diabetes in 2016 is estimated at more than 3.3 million patients treated. Type 1 diabetes (T1DM) represents 5.6% of diabetic patients (approximately 185,000 patients).
- Trial name
- NCT05662657
- Testing
- Diagnostic Test: PCL-S Questionnaire
- Where
- 2 sites in France
- Volunteers
- 297 people
- Sponsor
- Hospital St. Joseph, Marseille, France
Diabetes, Type 1 Diabetes
Looping Whilst Restricting Carbohydrates
To investigate the efficacy, safety and utility of hybrid closed-loop glucose control during a low carbohydrate vs. iso-energetic balanced diet in individuals with type 1 diabetes.
- Trial name
- LINEAR (NCT03932630)
- Testing
- Low carbohydrate diet, balanced diet
- Where
- Switzerland
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Diabetes Mellitus, Type 1
Effects of Structured Group Education on Quality of Life and Glycemic Control in Type 1 Diabetes
Patients with type 1 diabetes aged 15-65 years without major complications will be randomized either to usual care or to a structured group education program, with 6 four-hour weekly interactive sessions devoted to diabetes…
- Trial name
- NCT02443532
- Testing
- Structured group education, Individual education
- Volunteers
- 72 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Type 1 Diabetes Mellitus
Examining the Influence of Guided Meditation on Diabetes-related Distress and Glycemic Control
The study aims to investigate the effects of Guided Meditation on diabetes-related distress and glycemic control in hospitalized Type 1 adolescent diabetic patients.
- Trial name
- NCT06151821
- Testing
- Guided meditation
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Shifa International Hospital
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Effectiveness and Safety Study of the Abbott Sensor Based Glucose Monitoring Systems
The purpose of the study is to evaluate the safety and effectiveness of the Abbott Sensor Based Glucose Monitoring System Personal (System-P) and Abbott Sensor Based Glucose Monitoring System Professional (System-Pro) when used…
- Trial name
- NCT02283411
- Testing
- Abbott Sensor Based Glucose Monitoring System
- Where
- 6 sites in United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Abbott Diabetes Care
Type 1 Diabetes
Pancreas Volume in Preclinical Type 1 Diabetes
Type 1 diabetes (T1D) is characterized by a progressive destruction of insulin producing beta cells, resulting in a lifelong dependence on exogenous insulin.
- Trial name
- NCT02234947
- Testing
- MRI, US, and blood samples
- Where
- United States
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- University of Florida
Type 1 Diabetes
Transition Preparation Intervention for Young Adults With Type 1 Diabetes
The purpose of this research study is to find out more about how to support young adults (ages 18-22) with type 1 diabetes as they prepare to transition from pediatric and adult endocrinology medical care.
- Trial name
- NCT03998475
- Testing
- Transition preparation intervention
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Virginia Commonwealth University
Nocturnal Hypoglycemia, Type 1 Diabetes
Prevalence of Nocturnal Hypoglycemia in Children on a Type 1 Diabetes (TID) Insulin Regimen Using a Continuous Glucose Monitoring System (CGMS)
This study will help determine the frequency and magnitude of nocturnal hypoglycemia (low blood sugar at night during sleep), in children with type 1 diabetes who are on a standard insulin regimen, by using a Continuous Glucose…
- Trial name
- NCT00542334
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Children's Hospital of Eastern Ontario
Nephropathy, Diabetic Nephropathies
Prevention of Chronic Kidney Disease(CDK) Progression in Type 1 Diabetes With Long Term Use of Sodium-Glucose-coTransporter Inhibitors Avoiding Kidney hypOxia
Background: Sodium-glucose-cotransporter (SGLT) inhibition has been observed to reduce risk of cardiovascular events and kidney failure in persons with type 2 diabetes.
- Conditions
- Nephropathy, Diabetic Nephropathies, Diabetes Mellitus, Type 1, Albuminuria
- Trial name
- PLUTO (NCT06147232)
- Testing
- Sotagliflozin
- Where
- 2 sites in Denmark, United Kingdom
- Volunteers
- 69 people
- Sponsor
- Steno Diabetes Center Copenhagen
Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
Effects of HBO on Glucose in Patients With DM
The purpose of this Research Study is: 1. To determine the reliability and performance of the Dexcom G6® continuous glucose monitoring (CGM) system in patients with diabetes undergoing hyperbaric oxygen (HBO2) exposure.
- Trial name
- NCT04261738
- Testing
- Hyperbaric Oxygen
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Legacy Health System
Diabetes Mellitus, Type 1
Effect of Methyldopa on MHC Class II Antigen Presentation in Type 1 Diabetes
Type 1 Diabetes is an autoimmune condition in which segments of the immune system cause the destruction of insulin producing cells in the pancreas, leaving individuals with an impaired ability to control blood glucose levels.
- Trial name
- NCT01883804
- Testing
- Methyldopa
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Colorado, Denver
Diabetes Mellitus, Type 1
Mindful Self-Compassion to Assist Emerging Adults With Diabetes Transition to Adulthood
The transition from pediatric to adult care is particularly difficult for individuals with Type 1 diabetes. It is hypothesized that a mindfulness-based intervention for individuals making this transition will contribute to…
- Trial name
- NCT03999385
- Testing
- Mindful Self-Compassion (MSC)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Manitoba
Type 1 Diabetes Mellitus
Cognitive Adaptations to Reduce Emotional Stress Associated With Type 1 Diabetes
The purpose of this study is to evaluate a new intervention (CARES: Cognitive Adaptations to Reduce Emotional Stress Associated with Type 1 Diabetes) designed to reduce caregiver depressive symptoms in families of children with…
- Trial name
- CARES (NCT03698708)
- Testing
- CARES Intervention
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Kansas Medical Center
Type 1 Diabetes Mellitus, Dyslipidemia
Clinical Trial of Zocor (Simvastatin) and Vytorin (Ezetimibe/Simvastatin) in Adolescents With Type 1 Diabetes
The purpose of the study is to establish the safety of ezetimibe/simvastatin and simvastatin in adolescents with Type 1 Diabetes and to determine the amount of decrease in LDL-cholesterol.The study hypothesizes that simvastatin…
- Trial name
- NCT00477204
- Testing
- Simvastatin, Ezetimibe/Simvastatin
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Colorado, Denver
Diabetes Mellitus, Type 1
Influence of Binge Drinking on Glucose Metabolism in Patients With Type 1 Diabetes - A Pilot Study
Although there is no evidence that individuals with type 1 diabetes have a different approach to alcohol compared to the background population, nevertheless, its use does have implications for patients mainly because of the risk…
- Trial name
- NCT00135915
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- The Royal Bournemouth Hospital
Type 1 Diabetes Mellitus
Assessment of Quality of Life and Satisfaction With Medical Care of Pediatric Type 1 Diabetes Mellitus Patients
The purpose of this study is to evaluate the change score for the PedsQL short form Diabetes and Core Modules and the Patient Assessment of Chronic Illness Care measured at baseline (before changing care delivery models) and 12…
- Trial name
- NCT00450489
- Where
- United States
- Sponsor
- Children's Mercy Hospital Kansas City
Lipodystrophy, Obesity
Adipocyte, Insulin-resistance and Immunity : Evaluation of Interleukin-7 in Lipodystrophy, Diabetes and Obesity
White adipose tissue-related diseases spread from excess (obesity) to lack (lipoatrophies) through aberrant distribution (lipodystrophies), these 3 different disorders being paradoxically able to induce a metabolic insulin…
- Conditions
- Lipodystrophy, Obesity, Type 2 Diabetes
- Trial name
- IL-7norm (NCT01784289)
- Where
- 5 sites in France
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
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