Clinical trials: Endocrine Disorder
Type 2 Diabetes Mellitus (T2DM), Periodontal Disease
Serum Chromium, Nickel, and Magnesium in Type 2 Diabetic Periodontitis
Periodontitis is a chronic immunoinflammatory disease that has been increasingly associated with systemic conditions, particularly type 2 diabetes mellitus (T2DM).
- Trial name
- NCT07327086
- Testing
- No intervention (Observational study)
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Behavioral Economics, Primary Health Care
Primary Care Clinical Excellence Incentive Study
As part of UCLA Health's commitment to developing a premier integrated health system built on a foundation of physician-led, team-based primary care, the Department of Medicine (DOM) recently implemented a new performance based…
- Conditions
- Behavioral Economics, Primary Health Care, Health Maintenance, Diabetes
- Trial name
- PCCE (NCT04237883)
- Testing
- Standard communication email, Social comparison Intervention, Leadership Training
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Periodontitis, Diabetes
Gingival Crevicular IL-34 and CSF-1 Levels in Patients With Periodontitis and Uncontrolled Type 2 Diabetes
Type 2 diabetes mellitus is a metabolic disorder. There is a bidirectional association between periodontal disease and DM. Currently there is no data relationship between CSF-1 and IL-34, periodontal disease and diabetes.The aim…
- Trial name
- NCT04891627
- Testing
- Gingival crevicular fluid
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Uşak University
Pancreas Cancer, Diagnosis
Diagnosis of Pancreatic Cancer by Purine Metabolite (Hypoxanthine, Xanthine) in Urine
This study aim to develope a diagnostic method of pancreatic cancer by using a reagent for analyzing purine metabolite (Hypoxanthine, Xanthine) in urine. It is safe and cost effective compare to radiologic or blood test.
- Trial name
- NCT06291779
- Testing
- Purine metabolite (Hypoxanthine, Xanthine) in urine by CubeBio
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ho-Seong Han
Obesity, Growth Hormone
Prevalence and Cardiovascular Effects of Growth Hormone Deficiency in Abdominal Obesity
Obesity is one of the leading causes of cardiovascular-related diseases, including diabetes and heart disease. Obesity, and more specifically abdominal obesity, may cause decreased growth hormone (GH) levels.
- Trial name
- NCT00562796
- Where
- United States
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Osteoarthritis
Effects of Osteoarthritis Pain, Morphine, and Placebo on Neuroendocrine Function in Men
This study will examine the effects of morphine on leuteinizing hormone, testosterone, adrenocorticotropic hormone and cortisol in men.
- Trial name
- NCT00088296
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Appetitive Behavior, Obesity
Impact of Slowly Digestible Carbohydrates on the Gut-brain Axis
Our laboratory is investigating the physiological outcomes and health benefits of the consumption of high-quality carbohydrates.
- Conditions
- Appetitive Behavior, Obesity, Diabetes Mellitus, Type 2
- Trial name
- NCT05349903
- Testing
- Rice flour, Alternanoligosaccharide 15, Inulin
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Purdue University
Sarcoma, Endocrine Tumors
Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological Studies
Background: Laboratory investigators who are studying common childhood cancers are interested in developing a tissue repository to collect and store blood, serum, tissue, urine, or tumors of children who have cancer or adults who…
- Conditions
- Sarcoma, Endocrine Tumors, Neuroblastoma, Retinoblastoma
- Trial name
- NCT01109394
- Where
- 5 sites in United States
- Volunteers
- 6,035 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Medication Adherence, Mental Health Issue
Integrating a Mental Health Intervention Into Primary Health Care for Refugees
The objective of this study is to evaluate the impact of an evidence-based mental health intervention (Common Elements Treatment Approach) on medication adherence, behavioral improvement and clinical outcomesamong adults taking…
- Conditions
- Medication Adherence, Mental Health Issue, Self Efficacy, Hypertension
- Trial name
- NCT05512624
- Testing
- Common Elements Treatment Approach
- Where
- Thailand
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- International Rescue Committee
Diabetes Mellitus, Type 2
Albiglutide Thorough ECG Study in Healthy Volunteers
This study is designed to investigate the effect of treatment with albiglutide on the cardiac repolarization (corrected QT interval) in healthy male and female subjects.
- Trial name
- NCT01406262
- Testing
- Albiglutide, Moxifloxacin
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Diabetes
User Evaluation of a Home-collection Kit for People With Diabetes
Type 1 and Type 2 are the most common types of diabetes mellitus. Although the cause of Type 1 is different to Type 2, they can both lead to high blood glucose levels as the patient is unable to store and use sugar.
- Trial name
- NCT06038669
- Testing
- Dried blood spot device, Healthcare professional interviews
- Where
- United Kingdom
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University Hospitals of North Midlands NHS Trust
Endocrine Diseases
Male:Female Birth Ratios and Phthalate Levels
Objective 1: To assess environmental exposure to chemicals/toxins, including phthalates, among rural and urban Mexican American men and women (n=300), aged 18 to 40, in urban Baytown, TX and rural Rio Grande Valley (Hidalgo…
- Trial name
- NCT00903318
- Testing
- Questionnaire
- Where
- 3 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Vitamin D Deficiency, Pre-Eclampsia
Vitamin D in Pregnancy
Danish pregnant women are recommended ad daily vitamin D supplement of 10 µg. Despite the fact that 9 out of 10 women take vitamin D supplements, more than 40% of pregnant women are vitamin D deficient, putting them at an…
- Conditions
- Vitamin D Deficiency, Pre-Eclampsia, Fetal Growth Retardation, Gestational Diabetes
- Trial name
- GRAVITD (NCT04291313)
- Testing
- Vitamin D3 (90µg), Vitamin D3 (10µg)
- Where
- 2 sites in Denmark
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Type II Diabetes
A Study to Investigate the PK and Safety of CKD-393
A clinical trial to investigate the pharmacokinetics and safety after oral administration of CKD-393
- Trial name
- NCT04768673
- Testing
- CKD-393 formulation I, CKD-393 formulation II, D501, D759, H053
- Where
- South Korea
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Type 2 Diabetes, PreDiabetes
Promote Health With Digital Tools Among Adults With Type 2 Diabetes/Prediabetes and/or Hypertension
The goal of this hybrid type II effectiveness-implementation trial is to evaluate whether an intersectoral, digitally enabled, family-based intervention can prevent and manage type 2 diabetes mellitus (T2DM) and hypertension…
- Conditions
- Type 2 Diabetes, PreDiabetes, Hypertension, Obesity & Overweight
- Trial name
- DigiCare4You (NCT05648383)
- Testing
- mHealth self-management intervention, Standard care
- Where
- 4 sites in Albania, Bulgaria and 2 more
- Volunteers
- 1,215 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Diabetic Retinopathy, Retinal Vein Occlusion
Computer Aided Diagnosis of Multiple Eye Fundus Diseases From Color Fundus Photograph
Blindness can be caused by many ocular diseases, such as diabetic retinopathy, retinal vein occlusion, age-related macular degeneration, pathologic myopia and glaucoma.
- Conditions
- Diabetic Retinopathy, Retinal Vein Occlusion, Retinal Artery Occlusion, Central Serous Chorioretinopathy
- Trial name
- NCT04723160
- Testing
- Software assisted imaging diagnosis
- Where
- 5 sites in China
- Volunteers
- 748 people, healthy volunteers welcome
- Sponsor
- Visionary Intelligence Ltd.
Type 2 Diabetes
Simulated Diabetes Training for Resident Physicians
The objective of this translational research is to study the effect of implementing an innovative simulated diabetes learning intervention within primary care residency programs.
- Trial name
- SDT (NCT00979823)
- Testing
- Early SimCare Diabetes Group, Delayed SimCare Diabetes Group
- Where
- United States
- Volunteers
- 341 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Diabetes
Preventing Hypoglycemia
The purpose of the project is to improve in-patient safety by lowering the risk of severe hypoglycemia (low blood sugar) for patients with diabetes on insulin therapy and to improve communication between healthcare providers.
- Trial name
- NCT01923688
- Testing
- Informatics Alert/Nurse/physician responders
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Primary Ovarian Insufficiency, Premature Menopause
Causes and Consequences of Primary Ovarian Insufficiency
100 women with primary ovarian insufficiency will be included for extensive diagnostic workup to improve diagnostic precision by extended autoantibody screening and genetic and toxicological testing.
- Trial name
- Clinical POI (NCT04082169)
- Where
- Norway
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
In Vitro Fertilization, Polycystic Ovary Syndrome
Comparative Study of Long-acting and Short Acting Triptorelin in PCOS Patients Who Underwent IVF/ICSI
To test whether long-acting Triptorelin on pituitary down-regulation can improve the clinical pregnancy rate and reduces the incidence of ovarian hyperstimulation syndrome (OHSS) in infertile high-risk patients with polycystic…
- Trial name
- NCT02477566
- Testing
- Long-acting Triptorelin, Short-acting Triptorelin
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nanjing University
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