Clinical trials: Endocrine Malignancy
Endocrine Disorders, Hypertension
EndoSense: Continuous Real-Time Monitoring of Health Markers in Endocrine and Metabolic Disorders
The goal of this trial is to learn whether wearable devices and hormone sampling can measure how the body changes during daily-life challenges in adults with endocrine or metabolic disorders.
- Conditions
- Endocrine Disorders, Hypertension, Primary Aldosteronism, Cortisol Excess
- Trial name
- EndoSense (NCT07727356)
- Testing
- Sequential Dietary Sodium Modulation
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Felix Beuschlein
Ovarian Cancer
Glycan Analysis in Diagnosing Cancer in Women With Ovarian Epithelial Cancer and in Healthy Female Participants
RATIONALE: New diagnostic procedures, such as glycan analysis, may be effective in finding ovarian epithelial cancer. PURPOSE: This clinical trial is studying how well glycan analysis works in diagnosing cancer in women with…
- Trial name
- NCT00628654
- Where
- United States
- Volunteers
- 581 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Polycystic Ovary Syndrome
Women With Polycystic Ovary Syndrome (PCOS)
Metabolic profile in women of different body composition with polycystic ovary syndrome.
- Trial name
- PCOS (NCT02467751)
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Irmandade da Santa Casa de Misericordia de Sao Paulo
Ovarian Cancer, Peritoneal Metastases
Diffusion-weighted Imaging Study in Cancer of the Ovary
This project seeks to develop a quantitative imaging biomarker for evaluating and monitoring treatment response in ovarian cancer metastases and assess its potential in monitoring treatment response.
- Trial name
- DISCOVAR (NCT01505829)
- Where
- 6 sites in United Kingdom
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Institute of Cancer Research, United Kingdom
Polycystic Ovary Syndrome (PCOS)
A Randomized Controlled Trial of Acupuncture for Insulin Resistance in Patients With Polycystic Ovary Syndrome
To determine the efficacy and safety of 2 different treatment modalities: 1) acupuncture plus lifestyle management (treatment group), 2) placebo plus lifestyle management (control group) in the treatment of insulin resistance in…
- Trial name
- NCT06306417
- Testing
- lifestyle intervention, acupuncture
- Where
- China
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Hyperandrogenemia, Polycystic Ovary Syndrome
Evaluation of Adrenal Androgens in Normal and Obese Girls After Suppression and Stimulation
Women with polycystic ovary syndrome (PCOS) often have irregular menstrual periods, too much facial and body hair, and weight gain. Women with PCOS also have a hard time becoming pregnant.
- Conditions
- Hyperandrogenemia, Polycystic Ovary Syndrome, Obesity
- Trial name
- NCT01421797
- Testing
- Dexamethasone, Cortrosyn
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Virginia
No Condition
Comparison of Clinical Outcomes Between IVM and Minimal Stimulation IVF in Patients With PCOS
Polycystic ovarian syndrome (PCOS) is most common endocrinologic disease in women of reproductive age with incidence of 6.6 ~ 8%.
- Trial name
- NCT03134482
- Testing
- IVM, Minimal stimulation IVF
- Where
- 2 sites in South Korea
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- CHA University
Pancreatic Cancer
Secretin-Stimulated Magnetic Resonance Cholangiopancreatography (S-MRCP) in Pancreatic Patients
The aim of our study is to evaluate the utility of Secretin-Stimulated Magnetic Resonance Cholangiopancreatography (S-MRCP) in detecting carcinoma and precancerous lesions in patients with a significant family history of…
- Trial name
- NCT01094561
- Testing
- Synthetic Human Secretin, Secretin-Enhanced Magnetic Resonance Cholangiopancreatography, Secretin-Enhanced Endoscopic Ultrasound
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Elizabeth Hecht
Ketosis, Resistance Exercise
Acute Effects of Ketone Monoester Co-Ingestion With Dietary Protein on Whole-Body Phenylalanine Oxidation, Phenylalanine Retention, and Myofibrillar Protein Breakdown Following Resistance Exercise in Older Males
The goal of this trial is to determine if ketone monoester supplementation in conjunction with protein supplementation in the post exercise period can augment whole-body protein metabolism following resistance exercise in older…
- Conditions
- Ketosis, Resistance Exercise, Dietary Protein, Aging
- Trial name
- KET-OLD-M (NCT07884513)
- Testing
- Ketone Monoester + Dietary Protein (KET+PRO), Dietary Protein (PRO), Resistance Exercise
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- McGill University
BRCA Mutation, Ovarian Cancer
Prediction of Germline BRCA 1/2 Genes From Healthy Ovaries
The project aims at enhancing performance metrics and prospectively validating a radiogenomics model based on ovarian US images for predicting germline breast cancer susceptibility gene 1 and/or 2 (BRCA) status in women with…
- Conditions
- BRCA Mutation, Ovarian Cancer, Ultrasound Therapy; Complications
- Trial name
- PROBE-II (NCT05769517)
- Testing
- Germinal BRCA
- Where
- Italy
- Volunteers
- 6,465 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Quality of Life, Stroke, Acute
Cerebrovascular Disease: Quality of Life (CODE: QoL)
The goal of this observational study is to learn about quality of life, stress and caregiver burden in patients with stroke and their caregivers.
- Conditions
- Quality of Life, Stroke, Acute, Sexual Behavior, Stress
- Trial name
- CODE:QoL (NCT06443268)
- Testing
- questionnaire, hair samples, blood samples, clinical exam
- Where
- Switzerland
- Volunteers
- 680 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Metabolic Syndrome, Hypogonadism
Symptoms and Clinical Signs of Hypogonadism in Testicular Cancer Survivors
The purpose of this study is to investigate the prevalence of signs and symptoms of hypogonadism in three groups of testicular cancer survivors.
- Conditions
- Metabolic Syndrome, Hypogonadism, Cardio-vascular Disease
- Trial name
- NCT02240966
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pancreatic Carcinoma
Personalized Education and Genetic Counseling to Increase Genetic Testing in Patients With a Known Family History of Pancreatic Cancer
This clinical trial studies whether personalized education and genetic counseling increases genetic testing in patients with a known family history of pancreatic cancer.
- Trial name
- NCT06744595
- Testing
- Biospecimen Collection, Educational Intervention, Electronic Health Record Review
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Thyroid Neoplasm, Lymphatic Metastasis
Prophylactic Selective Lateral Neck Dissection in Patients With Papillary Thyroid Carcinoma
The purpose of this study is to prospectively analyze the incidence of occult lateral neck metastasis (LNM) and to elucidate the factors that predict LNM in papillary thyroid carcinoma (PTC) with central neck metastasis (CNM) by…
- Trial name
- NCT01103557
- Testing
- prophylactic selective lateral neck dissection
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Pusan National University Hospital
Breast Cancer, Thyroid Cancer
3-D Super Resolution Ultrasound Microvascular Imaging
This is a 3-arm single center study of 45 patients. These cohorts will include 15 breast patients scheduled to undergo a biopsy, and 15 thyroid patients scheduled to undergo fine needle aspiration, biopsy, or thyroidectomy that…
- Trial name
- NCT04136912
- Testing
- Definity, Acoustic Angiography
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Polycystic Ovary Syndrome
Effect of High Testosterone on Sleep-associated Slowing of Follicular Luteinizing Hormone (LH) Frequency in Polycystic Ovary Syndrome
The purpose of this study is to determine whether a testosterone receptor blocker (flutamide) will normalize sleep-wake luteinizing hormone pulse frequency relationships in women with polycystic ovary syndrome.
- Trial name
- CRM004 (NCT00930228)
- Testing
- Flutamide
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Polycystic Ovary Syndrome
Resting Metabolic Rate, Fat Distribution, Endocrine and Metabolic Features in Polycystic Ovary Syndrome
In a longitudinal, prospective and observational study, patients with PCOS and controls wore the SenseWear Armband for 2 days. Resting metabolic rati (kcal/die), total energy expenditure (MET, kcal) were evaluated.
- Trial name
- NCT03132545
- Testing
- SenseWear Armband (SWA) monitoring, total body dual-energy X-ray absorptiometry
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Ovarian Cancer, Endometrial Cancer
Predictors of Ovarian Cancer and Endometrial Cancer for Artificial-Intelligence-Based Screening Tools
The goal of this observational study is to explore the possible associated factors of ovarian cancer and endometrial cancer in Indonesia and develop screening tools that could predict the risk of both types of cancer The specific…
- Conditions
- Ovarian Cancer, Endometrial Cancer, Endometrial Hyperplasia
- Trial name
- NCT05697601
- Testing
- Artificial-Intelligence Based Screening Tools, Pathology analysis
- Where
- Indonesia
- Volunteers
- 2,905 people, healthy volunteers welcome
- Sponsor
- Hasanuddin University
PCOS, Reproductive Age
Adipokines in Polycystic Ovary Syndrome
The aim of the study is to compare the concentrations of leptin, resistin, and omentin-1 in women across three research groups: those with polycystic ovary syndrome without insulin resistance, those with polycystic ovary syndrome…
- Trial name
- NCT06793072
- Testing
- Leptin concentration in blood serum, Resistin concentration in blood serum, Omentin-1 concentration in blood serum
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Brain Cancer, Breast Cancer
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
This is an observational case-control study to train and validate a genome-wide methylome enrichment platform to detect multiple cancer types and to differentiate amongst cancer types.
- Conditions
- Brain Cancer, Breast Cancer, Bladder Cancer, Cervical Cancer
- Trial name
- CAMPERR (NCT05366881)
- Where
- 17 sites in United States
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- Adela, Inc
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