Clinical trials: Endocrine Malignancy
Goiter, Nodular, Total Thyroidectomy
Thyroid Cancer in Surgical Treated Multinodular Goiter
This study aims to investigate, based on existing knowledge, the incidence of occult thyroid carcinoma in a cohort of patients with MNG, providing new insights into the prevalence and characteristics of thyroid malignancies in…
- Conditions
- Goiter, Nodular, Total Thyroidectomy, Thyroid Cancer
- Trial name
- NCT06924242
- Testing
- total or partial thyroidectomy
- Where
- Italy
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- University of Foggia
Ovarian Cancer
Blood Test for Ovarian Cancer Associated Antibodies (CAAb)
Blood is collected from patients and cultured in a CimTube (a test tube with stimulation media) for several days. Following the culture step, the supernatant fluid is tested for the presence of CAAb on experimental test kits.
- Trial name
- NCT00327925
- Testing
- Find Cancer Associated Antibodies
- Where
- 5 sites in Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lab Discoveries Ltd.
Obesity, Gender
Work-Related Effects of Heat, Activity, and Fat in Middle Aged Men
Obesity is associated with many undesirable health effects and disease, and middle age is associated with increased risk for disease.
- Conditions
- Obesity, Gender, Problem of Aging
- Trial name
- NCT02532725
- Testing
- Cardiopulmonary Exercise Stress Test, Climatic-Controlled Cardiopulmonary Exercise Stress Test, Body Composition Evaluation
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Freeman-Sheldon Research Group, Inc.
Polycystic Ovary Syndrome
Theca Cell Function in Women With Polycystic Ovary Syndrome (PCOS)
The mechanism for increased androgen production in women with polycystic ovary syndrome (PCOS) is not well understood. Excess androgen production by the ovary is stimulated by increased pituitary luteinizing hormone (LH)…
- Trial name
- NCT00747617
- Testing
- recombinant human chorionic gonadotropin
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Polycystic Ovary Syndrome
Absorption and Tolerability Studies of an Emulsion Containing the Coconut Oil-derived Glycerol Tridecanoate in Healthy Men
The primary aim of the study is to test safety and tolerance of oral intake of GT oil in the form of a non-diary based emulsion (10g of GT per emulsion) in healthy men.
- Trial name
- NCT03255889
- Testing
- Glyceryl Tridecanoate
- Where
- Singapore
- Volunteers
- healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Lung Cancer, Pulmonary Nodule
Exhaled Breath Electronic Nose for Multi-Disease Risk Prescreening
This prospective multicenter observational study will evaluate whether an electronic nose that analyzes patterns in exhaled breath can be developed as a noninvasive tool for early risk prescreening across several disease areas.
- Conditions
- Lung Cancer, Pulmonary Nodule, Chronic Respiratory Disease, Metabolic Disease
- Trial name
- BREATH-PAN (NCT07804017)
- Testing
- Electronic-Nose Breath Assessment
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Polycystic Ovarian Syndrome
The Effects of Letrozole And Clomiphene Citrate For Induction of Ovulation In Polycystic Ovarian Syndrome(PCOS)
As both medications i.e. CC and letrozole have been shown to be effective in inducing ovulation in PCOS patients, this study was performed in order to evaluate which regime (whether CC or letrozole) is the best to be used as the…
- Trial name
- NCT01577017
- Testing
- Letrozole
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Nik Hazlina
Ovarian Cancer
Chemotherapy-Related Toxicities In Ovarian Cancer Patients
Primary Objectives: 1. To assess the preferences of women with ovarian cancer, their clinical caregivers, familial caregivers, and a control group for toxicities associated with chemotherapy.
- Trial name
- NCT00508378
- Testing
- Interview, Questionnaire
- Where
- United States
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Pancreatic Cancer, Breast Cancer
The Clinical Application Value of SPECT Imaging Targeting LRRC15 in Malignant Tumors
Here's a polished version of the text: "This project involves patients with high-expression LRRC15 malignant tumors who are either clinically suspected of or diagnosed with pancreatic cancer, breast cancer, lung cancer, ovarian…
- Conditions
- Pancreatic Cancer, Breast Cancer, Lung Cancer, Sarcoma
- Trial name
- NCT07651020
- Testing
- Specific SPECT imaging agents targeting LRRC15
- Where
- China
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Dysmenorrhea Primary, Dysmenorrhea
Effect of 'Cramp Bites' on Period Cramps in Women Aged 18-25
85 percent of women of reproductive age experience consistent period cramps/menstrual pain, and 60% indicate that they do not use painkillers to relieve menstrual symptoms; there is a need for natural and non-medicative…
- Conditions
- Dysmenorrhea Primary, Dysmenorrhea, Menstrual Discomfort, Menstrual Problem
- Trial name
- NUTRITION; GYN (NCT06227676)
- Testing
- Cramp Bites by Aunt Flo's Kitchen
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cornell University
Thyroid, Papillary Thyroid Cancer
A Study of Online Follow-up in Patients With Papillary Thyroid Cancer
The randomized, actively controlled, non-inferiority trial is scheduled to begin in August 2024 and run through August 2026. Inclusion criteria: (1) has undergone microwave ablation of thyroid or thyroidectomy (including…
- Trial name
- NCT06800482
- Testing
- online outpatient follow-up
- Where
- China
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Ovarian Cancer
Evaluation of Amino Acid Metabolism Changes in Ovarian Cancer
Ovarian cancer is associated with undernutrition in more than half of all cases. The current management of undernutrition-cachexia in cancer is not specific.
- Trial name
- AMINOCANCER (NCT06216496)
- Testing
- dynamic test for amino acid metabolism
- Where
- France
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Breast Cancer Females
Short-term Impacts of Endocrine Therapy on Cardiovascular and Brain Health Outcomes in Breast Cancer
Aromatase inhibitors are the most used endocrine therapy for hormone-positive breast cancer. While there is a clear linear relationship between the duration of aromatase inhibitor use and the cumulative incidence of…
- Trial name
- STRIVE (Acute) (NCT06781762)
- Testing
- N/A (Usual Care)
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy
Study of Glucagon, Ghrelin and Growth Hormone as Counterregulatory Hormones
Glucagon has been used for decades as a test of growth hormone (GH) reserve. The pathway by which GH is stimulated by glucagon is not established.
- Trial name
- NCT01795235
- Testing
- Saline, Glucagon, Atenolol
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Stroke, Spinal Cord Diseases
Use of tDCS Stimulation in Neurological and Gynaecological Conditions
The aim of the study is to test the effect of tDCS stimulation on upper and lower limb function in neurological patients and to reduce pain in gynaecological patients.
- Conditions
- Stroke, Spinal Cord Diseases, Nerve Root Disorder, Endometriosis
- Trial name
- tDCS (NCT06891690)
- Testing
- tDSC stimulation
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Polycystic Ovary Syndrome, Obstructive Sleep Apnea
Polycystic Ovary Syndrome (PCOS) and Sleep Apnea
Polycystic ovary syndrome (PCOS) affects 5-10% of women in the United States. Its onset is usually at the time of puberty with manifestations of menstrual irregularity, hirsutism, and obesity.
- Trial name
- NCT00203996
- Testing
- continuous positive airway pressure (CPAP), depot leuprolide plus estrogen/progestin replacement, pioglitazone
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Polycystic Ovary Syndrome (PCOS)
Protein and Polycystic Ovary Syndrome (PCOS)
Polycystic ovary syndrome (PCOS) is a significant public health problem and is one of the most common hormonal disturbances affecting women of reproductive age.
- Trial name
- NCT07158723
- Testing
- Higher protein dietary pattern, Calorie restriction
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Arkansas, Fayetteville
Colorectal Cancer, Gastric Cancer (GC)
Clinical Application of PET Imaging Targeting GPA33 in Malignant Tumors
This study is a diagnostic study. Patients and healthy volunteers with clinically suspected or confirmed colorectal cancer, gastric cancer, pancreatic cancer and other malignant tumors with high expression of GPA33 will be…
- Conditions
- Colorectal Cancer, Gastric Cancer (GC), Pancreatic Cancer
- Trial name
- NCT07172503
- Testing
- 68Ga-NOTA-GPA33 nanobody
- Where
- China
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Smoking Cessation
Yoga for Men Attempting Smoking Cessation
The purpose of this pilot study is to examine the feasibility and preliminary efficacy of a quit-smoking program that combines behavioral therapy with either yoga, or a health \& wellness program that serves as a contact control.
- Trial name
- NCT02055326
- Testing
- Cognitive Behavioral Therapy for Smoking Cessation, Yoga, Health & Wellness
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Anxiety, Stress
An Exploratory Investigation of a Supplement to Promote Cognitive Health Benefits
The Smart Supplement has 20 vitamins and minerals that have strong track records of demonstrating positive health effects, both physiologically and cognitively.
- Conditions
- Anxiety, Stress, Memory Deficits, Cortisol Overproduction
- Trial name
- NCT05523115
- Testing
- Heights Smart Supplement
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Heights
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