Clinical trials: Endometrial
Vasomotor Symptoms, Endometrial Safety
Study of Hot Flashes and Night Sweats in Postmenopausal Women Receiving Combination Raloxifene and Oral Estrogen
This pilot study was designed to explore the effects of combined treatment with raloxifene HCl 60 mg and oral 17 beta-estradiol 1mg/day on the number of vasomotor episodes (hot flashes plus night sweats) in postmenopausal women…
- Trial name
- NCT00332553
- Testing
- Raloxifene, medroxyprogesterone acetate, estrogen
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Uterine Sarcoma, Uterine Leiomyosarcoma
Ph 2 Elacestrant in ER Positive Uterine Sarcomas
This study is to evaluate the efficacy and safety of elacestrant, in participants with advanced estrogen receptor (ER)-positive uterine sarcomas.
- Conditions
- Uterine Sarcoma, Uterine Leiomyosarcoma, Endometrial Stromal Sarcoma, ESS
- Trial name
- NCT07467772
- Testing
- Elacestrant
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Endometrial Disorder
Correlation Between Adnexal Masses and Endometrial Thickness Measured With Ultrasound in Adults Women
This study explores the correlation between adnexal masses and endometrial thickness in adult women, using ultrasound as the primary diagnostic tool.
- Trial name
- NCT06763393
- Testing
- Ultrasound
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Superior University
Ovulation Disorder
"Stair Step Study"
Rationale: There is some information suggesting that a progesterone-induced withdrawal bleeding before the start of ovulation induction in women suffering from oligo- or amenorrhea reduces pregnancy and live birth rate.
- Trial name
- NCT03309176
- Testing
- Medroxyprogesterone Acetate 10 MG, Stair step protocol without Medroxyprogesterone Acetate
- Where
- 3 sites in Netherlands
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Luteal Phase Defect
Progesterone Levels and Clinical Outcomes Using a Single Pessary of 400 mg of Vaginal Progesterone in Substitutive Cycles for Embryo Transfer.
This study aims to compare the efficacy, in terms of progesterone levels and clinical outcomes, of two different presentations of micronized vaginal progesterone (400 mg vs.
- Trial name
- CycloCT (NCT04722471)
- Testing
- Vaginally administered progesterone
- Where
- Spain
- Volunteers
- 347 people, healthy volunteers welcome
- Sponsor
- Instituto Bernabeu
Adenocarcinoma of the Gastroesophageal Junction, Cervical Cancer
A Survivorship Care Plan for Gynaecological Cancer Patients
After treatment women surviving gynaecological cancer may experience lateeffects and longterm challenges specific to their disease and treatment resulting in functional deficits and a reduction in societal integration (Yabroff et…
- Conditions
- Adenocarcinoma of the Gastroesophageal Junction, Cervical Cancer, Endometrial Cancer, Esophageal Cancer
- Trial name
- NCT01582906
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Endometrial Receptivity
Impact of IVF Hormonal Therapy on Endometrial Receptivity and Endometrial Senescent Cell Pathological Accumulation
Both controlled ovarian stimulation (COS) and frozen embryo transfer has become an integral part of in vitro fertilization (IVF) treatment.
- Trial name
- HormoSenoRec (NCT06280560)
- Testing
- Controlled Ovarian Stimulation + Luteal Phase Support, Hormonal Replacement Therapy programmed artificial cycle, Natural Cycle (NC)
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fundación IVI
Infertility
Comparison of Transfers of Fresh and Thawed Embryos in High Responder Patients
This study tests the hypothesis that controlled ovarian stimulation impairs endometrial receptivity in high responders.
- Trial name
- NCT00963079
- Testing
- Embryo cryopreservation, Fresh blastocyst transfer
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fertility Center of Las Vegas
Endometriosis
Evaluation of Endometrial Stromal Cell Apoptosis in Adenomyosis
Our previous results revealed that the expression of killer inhibitory receptors (KIRs) on NK cells was decreased in eutopic endometrium in women with adenomyosis.
- Trial name
- NCT00172588
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Quality of Life, Cancer of Endometrium
FitEx for Endometrial Cancer Survivors
The purpose of this study is to determine whether a physical activity tracking program called FitEx would be useful to endometrial cancer survivors.
- Conditions
- Quality of Life, Cancer of Endometrium, Behavior, Health, Self Efficacy
- Trial name
- NCT05233059
- Testing
- FitEx, Weekly Yoga Sessions, Weekly Movement Sessions
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic
Healthy
Endometrial Effects of Daily Progesterone s.c. 25 and 50 Mg Aqueous Formulation to Female Healthy Volunteers
This is a multiple dose, observer blind, randomised, parallel groups pharmacodynamic and pharmacokinetic study to assess the endometrial effects (predecidual changes) of a new aqueous progesterone formulation administered s.c.
- Trial name
- NCT00377923
- Testing
- Progesterone
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- IBSA Institut Biochimique SA
Gynecologic Malignant Tumor
The Study of Massively Parallel Sequencing in Early Detection for Gynecologic Malignant Tumor
As human aging, 50% of women will be faced with the threat of cancer, especially gynecological malignancies. Ovarian, cervical and endometrial cancer are three major gynecological malignancies.
- Trial name
- NCT02166515
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zhiqing, Liang
Endometrial Receptivity;RNA; Progesterone
Clinical Study on Endometrial Receptivity
to explore the differential expression of miRNA in the implantation window of patients with endometriosis and the time of progesterone and route of administration on planting window
- Trial name
- NCT03687021
- Testing
- Progesterone
- Where
- China
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Asherman Syndrome
Pre-clinical Endometrial Tissular Renovation Study
The endometrium is a tissue with high capacity of renewal ("self-renewal"). This process is regulated by stem cells. Recent studies have shown that bone marrow-derived stem cells (BMDSCs) contribute to tissues and organs…
- Trial name
- PreENTIRE (NCT03665649)
- Testing
- CD133+ cells isolation
- Where
- Spain
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Igenomix
Endometrial Carcinoma
Low Dose Aspirin to Lower Inflammation and Prevent Endometrial Cancer in Postmenopausal Women With Non-atrophic Endometrial Changes and Pain
This phase IV trial studies whether low dose aspirin can be used to lower inflammation and prevent endometrial cancer in postmenopausal women with changes in the endometrial tissue that are not related to thinning (non-atrophic…
- Trial name
- NCT07281547
- Testing
- Biospecimen Collection, Low-Dose Aspirin, Patient Observation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Contraception
FC Patch Comparator Study
The purpose of this study is to compare bleeding pattern and safety of contraceptive patch SH P00331F to a marketed comparator.
- Trial name
- NCT00185354
- Testing
- BAY86-5016, SH P00331F, SH P00331N
- Where
- 28 sites in Austria, Finland and 2 more
- Volunteers
- 422 people, healthy volunteers welcome
- Sponsor
- Bayer
Repetitive Implantation Failure
ERA Test in Patients With Recurrent Implantation Failure
The purpose of this study is to demonstrate the clinical efficiency of the Endometrial Receptivity Array (ERA) diagnostic tool in patients with repetitive implantation failure (RIF), leading to the new concept of the personalized…
- Trial name
- ERA (NCT01668693)
- Testing
- ERA (Endometrial Receptivity Array), Personalized Embryo Transfer, Second ERA
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Igenomix
Endometrium Cancer
Risk Evaluation and Screening to Tailor Prevention and Reduce the Incidence of Endometrial Cancer
This study proposes to assess feasibility and acceptability of screening and risk reducing interventions in individuals at increased for endometrial cancer (EC).
- Trial name
- RESToRE (NCT05651282)
- Testing
- Provera
- Where
- Canada
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Endometrial Cancer
The Clinical Utility of DNA Methylation Testing in Patient-collected Urine and Vaginal Samples to Detect Endometrial Cancer: a Case-control Study
The goal of this observational case-control study is to investigate the use of DNA-methylation testing in patient-collected urine and vaginal samples to detect endometrial cancer.
- Trial name
- NCT06846775
- Testing
- DNA-methylation testing in patient-collected urine and vaginal samples
- Where
- 3 sites in Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Endometrium Cancer, Sentinel Lymph Node
Multimedia Aid Gynecologic Counseling and Consent
This is an interventional trial to introduce two short animated videos into preoperative counseling/consent and to compare patient comprehension and satisfaction with a multimedia approach compared to standard of care currently.
- Conditions
- Endometrium Cancer, Sentinel Lymph Node, Perioperative/Postoperative Complications
- Trial name
- NCT03899441
- Testing
- Video
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center