Clinical trials: Endoscopic Assessment
Chronic Obstructive Pulmonary Disease (COPD)
Lung Volume Reduction Via Coils in Patients With COPD
For patients with emphysema lung volume reduction (ELVR) could be an expedient approach for the reduction of distension of the lung. ELVR may be performed using RePneu® Coils.
- Trial name
- NCT02246569
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- RWTH Aachen University
Obesity
Safety and Feasibility of an Endoluminal-suturing Device (Endomina TM) for Gastric Reduction
Objectives: Study to evaluate safety and feasibility of an endoluminal vertical gastroplasty (EVG) using an endoluminal-suturing device.
- Trial name
- NCT02534662
- Testing
- ENDOMINA
- Where
- Belgium
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Theodor Bilharz Research Institute
Analgesics
A Safety Trial to Compare Different Analgesics in Combination With Low Dose Aspirin to Study Their Bleeding Properties and Their Effects on the Stomach
The purpose of this study is to compare several analgesics given in approved daily doses in combination with a daily cardioprotective dose of aspirin (81 mg), to study their bleeding properties and their effects on the stomach in…
- Trial name
- NCT00261586
- Testing
- aspirin, acetaminophen, ibuprofen, naproxen, celecoxib, rofecoxib
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
ERCP, Biomechanic
Evaluation of Biomechanical Forced During the Practice of Endoscopic Retrograde Cholangiopancreatography
A number of best practice recommendations have been developed to improve practitioner comfort, similar to those recommended for digestive surgeons.
- Conditions
- ERCP, Biomechanic, Musculoskeletal Disorders
- Trial name
- RADIO-ERGO (NCT07691580)
- Testing
- CAPTIV system
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Colorectal Neoplasms, Adenoma Colon
Surveillance Intervals After Piecemeal Resection of Non-pedunculated Colorectal Lesions ≥20mm
Intensive endoscopic surveillance following piecemeal resection of non-pedunculated colorectal lesions (NPCL) ≥20 mm is the current standard of care, given the high recurrence rate of these lesions (15-30%).
- Conditions
- Colorectal Neoplasms, Adenoma Colon, Colonic Polyps, Serrated Adenoma
- Trial name
- NCT06791616
- Testing
- Colonoscopy
- Volunteers
- 746 people
- Sponsor
- Asociación Española de Gastroenterología
Obesity
Efficacy and Results of Endoscopic Gastroplasty Using Overstitch in Patients With Class I and II Obesity
Obesity is a chronic disease that has grown to epidemic proportions in Brazil and throughout the world in recent years. Bariatric surgery has been the most effective method for the treatment and prophylaxis of complications…
- Trial name
- NCT03493620
- Testing
- Device arm
- Where
- 2 sites in Brazil
- Volunteers
- 60 people
- Sponsor
- Kaiser Clinic and Hospital
Inflammatory Bowel Disease, Crohn's Disease
Endoscopy and Endomicroscopy for Assessment of Mucosal Healing in Inflammatory Bowel Disease (IBD)
Inflammatory bowel disease (IBD) encompasses two major forms of chronic intestinal disorders, Crohn's disease and ulcerative colitis (UC).
- Conditions
- Inflammatory Bowel Disease, Crohn's Disease, Ulcerative Colitis
- Trial name
- NCT01524120
- Testing
- Endoscopy (EPK-i, Pentax, Tokyo, Japan), Endomicroscopy (iCLE, Pentax, Tokyo, Japan)
- Where
- Germany
- Sponsor
- University of Erlangen-Nürnberg Medical School
Gastro-Intestinal Disorder
Evaluation of the Impact of a Forward Viewing Scope at Time of ERCP
This study will be a prospective, tandem-designed study to determine the proportion of clinically significant missed lesions when using a side- or oblique-viewing endoscope as compared to the standard forward-viewing endoscope.
- Trial name
- NCT05627882
- Testing
- Forward viewing endoscope
- Where
- United States
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Gastrointestinal Disease
Pilot Study for Evaluation of Cryobiopsy and Correlation With Standard Forceps Biopsy
Environmental enteric dysfunction (EED) is a poorly understood condition characterized by intestinal inflammation and loss of barrier function that is prevalent in regions of the world with inadequate sanitation and hygiene.
- Trial name
- NCT03566160
- Testing
- Cryobiopsy probe, administered to study participants
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Patients Who Have Failed Conventional DPEJ Placement
Pilot to Assess DBE as a Rescue Technique for Failed PEJ
Is DBE(double balloon enteroscopy)-assisted DPEJ(direct percutaneous endoscopic jejunostomy) a viable option in patients who have failed conventional DPEJ placement and who otherwise would require surgical jejunostomy or…
- Trial name
- NCT01057940
- Testing
- DBE PEJ placement
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Gastrointestinal Bleeding
Early Endoscopy for Acute Upper Gastrointestinal Bleeding in Acute Coronary Syndrome Patients
The primary aim of this study is to compare efficacy of "early endoscopy" and "non-endoscopic treatment" for management of acute upper gastrointestinal (UGI) bleeding in patients with recent acute coronary syndrome (ACS).
- Trial name
- NCT02618980
- Testing
- endoscopic hemostasis
- Where
- Taiwan
- Volunteers
- 43 people
- Sponsor
- Far Eastern Memorial Hospital
Middle Ear Cholesteatoma
Associations of Pre- and Intraoperative Endoscopic Findings of Middle Ear Status in Cholesteatoma
The aim of this study is to assess the accuracy of preoperative HRCT of the temporal bone combined with the preoperative audiologic assessment compared with the intraoperative endoscopic middle ear finding.
- Trial name
- NCT04672187
- Where
- Thailand
- Volunteers
- 41 people
- Sponsor
- Prince of Songkla University
Colon Cancer, Natural Orifice Transluminal Endoscopic Surgery
Feasibility and Safety of Hybrid Transvaginal Natural Orifice Transluminal Endoscopic Surgery for Colon Cancer
This study aims to evaluate the safety and efficacy of radical colectomy with hybrid transvaginal natural orifice transluminal endoscopic surgery (hvNOTES).
- Trial name
- NCT04048421
- Testing
- hvNOTES radical colectomy
- Where
- 6 sites in China
- Volunteers
- 55 people
- Sponsor
- Renmin Hospital of Wuhan University
Lung Cancer
Can a Pulmonologist Reliably Assess the Tumor Burden on ROSE Slides Obtained From Pulmonary Nodules and Lymphadenopathy
The study is aimed at verifying if a pulmonologist can reliably assess the tumor burden for the extractive molecular analysis in ROSE samples obtained with endoscopic sampling procedures from intrathoracic lymphadenopathy and…
- Trial name
- NCT03845764
- Testing
- Rapid on-site evaluation
- Where
- 2 sites in Italy
- Volunteers
- 164 people
- Sponsor
- Maggiore Bellaria Hospital, Bologna
Breast Cancer Early Stage Breast Cancer (Stage 1-3), Breast Cancer Non-invasive Breast Cancer
Endoscopy/Robotic Assisted Nipple Skin Sparing Mastectomy
Non-inferiority study of video-assisted (endoscopic or robotic) skin- and nipple-sparing mastectomy compared to open mastectomy. The feasibility of the technique, oncological safety and cosmetic results will be studied.
- Conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3), Breast Cancer Non-invasive Breast Cancer, High Risk Breast Carcinoma
- Trial name
- NCT06823414
- Testing
- Video assisted mastectomy
- Where
- Spain
- Volunteers
- 126 people
- Sponsor
- Alejandra García-Novoa
Jaundice, Obstructive, Jaundice; Malignant
Microbiological Assessment of Bile in Patients Undergone to Endoscopic Retrograde Cholangiography (ERCP): the "Microbile Registry"
The study is a prospective evaluation of the microbial assessment in patients undergoing to ERC with naive papilla; the population includes all the indication to biliary drainage.
- Conditions
- Jaundice, Obstructive, Jaundice; Malignant, Choledocholithiasis, Biliary Stricture
- Trial name
- Microbile (NCT06115564)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Azienda Unità Sanitaria Locale della Romagna
Healthy
Development of Applications of PillCam™ Endoscopy and Patency Systems and Clinical Evaluation of Their Performance in Healthy Volunteers ("HEIGHT" Study)
This is a feasibility, prospective, single center, open label, uncontrolled clinical study, to evaluate the safety and preliminary efficacy of the different R\&D changes made and implemented in the existing PillCam Capsule…
- Trial name
- NCT03301909
- Testing
- PillCam™ Endoscopy System, Bowel prep combination
- Where
- Israel
- Volunteers
- 694 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Endoscopic Sphincterotomy, Cholangiocarcinoma
Cytological Evaluation of Biliary Epithelium After Endoscopic Sphincterotomy
PROTOCOL Introduction: The introduction of endoscopic retrograde cholangio-pancreatography (ERCP) and endoscopic sphincterotomy (ES) in 1974 has dramatically changed the treatment of biliary and pancreatic diseases.
- Trial name
- NCT01135732
- Testing
- brush cytology
- Where
- Greece
- Volunteers
- 56 people
- Sponsor
- University of Athens
GERD
Symptom Assessment in Adult Patients With Erosive GERD (Gastroesophageal Reflux Disease) or enGERD (Endoscopic-negative GERD) After Treatment With Pantoprazole (BY1023/M3-343)
The aim of this study is to compare investigator and patient-assessed gastroesophageal reflux disease symptoms in patients with erosive GERD or endoscopic-negative GERD (enGERD).
- Trial name
- NCT00336219
- Testing
- Pantoprazole
- Where
- 40 sites in Australia, Austria and 2 more
- Volunteers
- 628 people
- Sponsor
- Takeda
Gastric Focal Lesion
Comparative Study of the Magnetically Guided Capsule Endoscopy Versus High Definition Gastroscopy
A capsule steered by magnetic field force developed by Siemens and Olympus has recently been evaluated in a pilot series in man with encouraging results (Rey JF, Ogata H, Hosoe N, Ohtsuka K, Ogata N, Ikeda K, Aihara H, Pangtay I…
- Trial name
- NCT01555840
- Testing
- Magnetically Guided Capsule (MGCE)
- Where
- France
- Volunteers
- 189 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf