Clinical trials: Endoscopy, Digestive System
Gastro-esophageal Reflux, Endoscopic Fundoplication
Endoscopic Fundoplication With MUSE System
This is a spontaneous, prospective, monocentric, observational, cohort study, with the aim of evaluating the effect of ultrasound-guided endoscopic fundoplication using the Medigus Ultrasonic Surgical Endostapler (MUSESystem…
- Trial name
- NCT03669874
- Testing
- Endoscopic fundoplication
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- IRCCS San Raffaele
Crohn Disease
Advanced Non-Invasive Diagnostics in Inflammatory Bowel Disease
The purpose of this study is to determine whether Non-invasive endoscopic procedures (pillcam colon capsule endoscopy, PCCE) and non-ionizing radiological modalities (MR enterocolonography, MREC and ultrasound, US) - offer a…
- Trial name
- ANDI (NCT03134586)
- Testing
- Diagnostic imaging
- Where
- 3 sites in Denmark
- Volunteers
- 153 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Iron Deficiency Anemia, GastroIntestinal Bleeding
Pan-intestinal Capsule Endoscopy Versus Colonoscopy in Iron Deficiency Anemia or Overt GI Bleeding
The authors hypothesize that in patients with iron deficiency anemia or gastrointestinal bleeding, pan-intestinal capsule endoscopy is a safe and well tolerated procedure that may improve diagnostic yield comparatively to the…
- Trial name
- NCT04782986
- Testing
- Pan-intestinal capsule endoscopy
- Where
- Portugal
- Volunteers
- 100 people
- Sponsor
- Unidade Local de Saúde do Alto Ave, EPE
Pancreatic Cystic Lesion
Antibiotic Prophylaxis for Endoscopic Ultrasound Guided Fine Needle Aspiration of Pancreatic Cystic Lesions
The purpose of this study is to determine whether the use of antibiotic prophylaxis is appropriate when performing a pancreatic cyst fine needle aspiration guided by endoscopic ultrasonography.
- Trial name
- NCT02261896
- Testing
- Ciprofloxacin
- Where
- Spain
- Volunteers
- 226 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Esophageal Stricture
Budesonide Following Endoscopic Dilatation of Esophageal Strictures in Children.
Endoscopic balloon dilatation (EBD) is a common therapeutic procedure performed for esophageal strictures. While the etiologies of esophageal strictures are numerous - including congenital strictures, caustic injuries and…
- Trial name
- NCT07560462
- Testing
- Budesonide intervention
- Where
- Israel
- Volunteers
- 32 people
- Sponsor
- Shaare Zedek Medical Center
Dysphagia, Dysphagia, Esophageal
Per-oral Endoscopic Myotomy (POEM) in Patients with Postfundplication Dysphagia
Laparoscopic fundoplication represents the standard antireflux procedure, when conservative measures fail. However, any type of fundoplication may be accompanied by adverse events.
- Conditions
- Dysphagia, Dysphagia, Esophageal, Healthy
- Trial name
- VADYSMA (NCT06872255)
- Testing
- Per Oral Endoscopic Myotomy (POEM)
- Where
- 2 sites in Czechia, Slovakia
- Volunteers
- 30 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Colorectal Neoplasm, Colonic Polyps
Clinical Study of Real Time Colorectal Polyp Diagnosis During Colonoscopy - the VALID Colonoscopy Study
The investigators hypothesize that high definition colonoscopy with close focus narrow band imaging features has a high diagnostic accuracy for colorectal polyp histology, and can replace formal pathologic assessment in cases of…
- Trial name
- VALID (NCT01288833)
- Testing
- Close focus HD NBI Colonoscopy System
- Where
- 2 sites in United States
- Volunteers
- 558 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Pathologic Stage I Gastric Cancer AJCC v8, Colorectal Cancer
Clinical Trial to Evaluate the Efficacy and Safety of a Thoracic and Abdominal Endoscopic Surgical System
Evaluation of the efficacy and safety of thoracic and abdominal endoscopic surgical systems manufactured by Shenzhen Cornerstone Robotics Technology Co., Ltd. for use in general, gynaecological and thoracic surgical procedures.
- Conditions
- Pathologic Stage I Gastric Cancer AJCC v8, Colorectal Cancer, Esophageal Cancer, Hepatectomy
- Trial name
- NCT06587152
- Testing
- Robot-assisted surgery
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Cornerstone Robotics
Pancreatic Cancer
SurePathTM Liquid-based Cytology and Conventional Smear Cytology in Pancreatic Lesions
The SurePathTM has been approved by the FDA since 1997. Currently, the SurePathTM is used for endometrial cells, body fluids, bronchoscopy aspirates, and thyroid fine needle aspirates.
- Trial name
- NCT03606148
- Testing
- SurePathTM
- Where
- South Korea
- Volunteers
- 170 people
- Sponsor
- Seoul National University Hospital
Pancreatic Cancer
The Accurateness of Endoscopic Ultrasound Elastography in the Guidance of EUS-FNA in Solid Pancreatic Lesions
To evaluate the role and effectiveness of EUS elastography as the guidance for direction of the site of fine needle aspirate (FNA) for tissue acquisition of solid pancreatic lesions
- Trial name
- NCT04148755
- Testing
- Endoscopic ultrasound guided fine needle aspirate
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Gallbladder Disease, Pancreatitis
Prospective Evaluation of Idiopathic Pancreatitis: Role of Endoscopic Ultrasonography
The purpose of the study is to determine the best evaluation for patients with idiopathic (unexplained) pancreatitis.
- Trial name
- NCT00609726
- Where
- United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Endoscopy Competence
Gastrointestinal Endoscopist Warm-up Activity With Recreational Media
This study aims to assess the potential benefits of a brief video game intervention prior to a simulated endoscopy assessment on a phantom model by gastroenterology and general surgical clinicians.
- Trial name
- GET WARM (NCT07649447)
- Testing
- Video game warm-up.
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- William Shanahan
Esophageal and Gastric Varices
Study on Portal Vein Pressure Gradient Measurement Under Endoscopic Ultrasound Guidance for Gastric Fundal Varices
This study aimed to evaluate the feasibility and safety of direct gastric variceal pressure measurement in patients with large spontaneous portosystemic shunts, and to determine whether the gastric variceal pressure gradient…
- Trial name
- NCT07478770
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Healthy Individual
CDSS-assisted UGI Endoscopy vs. Routine Screening Endoscopy
This study aimed to find the CDSS-assisted upper GI endoscopy has clinical benefit compared to conventional routine screening upper GI endoscopy. Investigators will conduct a pilot randomized controlled study.
- Trial name
- NCT05452473
- Testing
- CDSS-assisted upper GI endoscopy, no intervention
- Where
- South Korea
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Chuncheon Sacred Heart Hospital
Early Gastric Cancer
Monitored Anesthesia Care With Propofol Plus Remifentanil During Endoscopic Submucosal Dissection: Evaluation of Bispectral Index Monitoring
There are clinical usefulness issues associated with bispectral index (BIS) for sedation of endoscopic submucosal dissection (ESD). However, the clinical usefulness of BIS for deep sedation is incompletely described.
- Trial name
- NCT01921283
- Testing
- BIS sensor attachment, no- BIS sensor attachment
- Where
- South Korea
- Volunteers
- 180 people
- Sponsor
- Yonsei University
Colon Disease, Gastric Disease
Feasibility Trial to Evaluate the Ability of the SuMO Tissue Access and Resection System
This feasibility trial will evaluate the ability of the SuMO Tissue Access and Resection System (Apollo Endosurgery, Austin, Texas).
- Trial name
- SUMO (NCT01322737)
- Testing
- Tissue Access and Resection System
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Iron Deficiency Anemia, Bowel Cancer
Capsule Endoscopy in Iron Deficiency Anaemia
This project aim to investigate whether wireless capsule endoscopy(WCE) has a similar diagnostic yield as conventional endoscopy in detecting the cause of iron deficiency anemia (IDA)
- Trial name
- WCE-IDA (NCT06219395)
- Testing
- Endoscopy
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Vastra Gotaland Region
Pancreatitis, Chronic, Pancreatic Duct Stone
Comparison of Efficacy of ESWL and Laser Lithotripsy in Chronic Pancreatitis With ERCP
This study will compare the efficacy of ESWL and Laser Lithotripsy in the treatment of pancreatic duct stones with ERCP.
- Trial name
- NCT05326542
- Testing
- ESWL and ERCP, LL and ERCP
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Changhai Hospital
Esophageal Neoplasm, Esophageal Polyp
Monopolar and Bipolar in Esophageal ESD
The objective of this study is to prospectively document the efficacy and clinical outcomes of Endoscopic Submucosal Dissection procedure that utilize either a novel Bipolar-Current ESD device or the standard monopolar…
- Conditions
- Esophageal Neoplasm, Esophageal Polyp, Endoscopic Submucosal Dissection, Bipolar Electocautery
- Trial name
- NCT05736705
- Testing
- Endoscopic Submucosal Dissection, Bipolar electrocautery knife
- Where
- United States
- Sponsor
- Baylor College of Medicine
Endoscopic Vacuum Therapy, Anastomotic Leak
Endoscopic Vacuum Therapy for Transmural Defects in the Upper Gastrointestinal Tract
The goal of this observational study is to learn about the best indications and techniques regarding endoscopic vacuum therapy (EVT) in patients with a transmural defect in the upper gastrointestinal (GI) tract (e.g.
- Conditions
- Endoscopic Vacuum Therapy, Anastomotic Leak, Esophageal Perforation, Esophageal Perforation, Traumatic
- Trial name
- NCT05606822
- Testing
- Observational
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)