Clinical trials: Endoscopy
Histopathology
Esophageal Mucosal Changes in Achalasia Cardia and Reversibility After Per Oral Endoscopic Myotomy - A Pilot Study
Esophageal mucosal changes in long standing achalasia cardia and reversibility after per oral endoscopic myotomy - A pilot study Aims and Objectives: To study mucosal changes in patients with achalasia cardia To study potential…
- Trial name
- NCT04463095
- Testing
- PER ORAL ENDOSCOPY MYOTOMY (POEM)
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Education
Simulation-based Training for Flexible Cystoscopy - a Patient Transfer Randomized Trial
Simulation training in surgical education in Urology specialist training in flexible cystoscopy has been demonstrated a valid and efficient learning instrument.
- Trial name
- NCT02411747
- Testing
- Testing, Directed self-regulated simulation training
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hypoxemia During Surgery
Prediction Model of Hypoxemia in Gastrointestinal Endoscopy Sedation
The incidence of hypoxemia during gastrointestinal endoscopy sedation is high, but there is still a lack of perfect prediction model of hypoxemia, which often leads to unpredictable respiratory complications.
- Trial name
- NCT06016998
- Where
- China
- Volunteers
- 1,023 people, healthy volunteers welcome
- Sponsor
- Sichuan Provincial People's Hospital
Aminophylline, Dexmedetomidine
Aminophylline on Recovery in Functional Endoscopic Sinus Surgery Under Dexmedetomidine Hypotensive Anesthesia
This study will be conducted to evaluate the effect of intravenous aminophylline on hemodynamics and recovery of patients receiving dexmedetomidine infusion during functional endoscopic sinus surgery.
- Conditions
- Aminophylline, Dexmedetomidine, Functional Endoscopic Sinus Surgery
- Trial name
- NCT05738135
- Testing
- Aminophylline group, normal saline
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Tanta University
Pancreatic Disease
EUS Ductal Evaluation in One Endoscopic Session for the Diagnosis of Exocrine Pancreas Disease
The purpose of this study is, to develop a standard of care protocol using the combination of EUS, ePFT, and sEUS during one endoscopic session (instead of the three separate endoscopic sessions).
- Trial name
- NCT01997476
- Testing
- Combined EUS, e-PFT and sEUS Testing
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Indiana University
Hypoxia, Gastric Polyp
The Efficacy and Safety of the COMBO Endoscopy Oropharyngeal Airway in Gastrointestinal Endoscopy Procedure
Hypoxia represents the prevailing adverse occurrence during the sedation of patients undergoing gastrointestinal endoscopy with propofol.
- Conditions
- Hypoxia, Gastric Polyp, Colon Cancer, Esophageal Cancer
- Trial name
- NCT06081647
- Testing
- the COMBO Endoscopy Oropharyngeal Airway, Regular Nasal Cannula
- Where
- 10 sites in China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Endoscopy
Evaluation of the Role of Endoscopic Ultrasound Guided Gastric Botulinum Toxin Injection in the Treatment of Obesity.
Background: Gastric injections of Botulinum toxin A (BTA) may induce changes in gastric emptying and body weight, but results vary. BTA dose and depth of injection may affect efficacy.
- Trial name
- NCT03901040
- Testing
- endoscopic ultrasound
- Where
- Egypt
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Bladder Injury, Prostate Hyperplasia
Anatomic Endoscopic Prostate Enucleation and BICEP Classification
The Bladder Injury Classification System for Endoscopic Procedure (BICEP) is designed to provide a systematic framework for categorizing bladder injuries that occur during endoscopic procedures.
- Trial name
- BICEP (NCT06469125)
- Testing
- Endoscopic Prostate Interventions for Anatomic Enucleation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Lichen Planus
Mucosal and Nasal Involvement and Their Correlation With Smell and Taste Functions in Lichen Planus Patients
This study investigates smell and taste function in patients diagnosed with lichen planus, a chronic inflammatory condition affecting the skin and mucous membranes.
- Trial name
- LP-NOSE (NCT07570706)
- Testing
- Grup 1 - Lichen Planus Patients Intervention Name: Taste and Smell Testing, Oral and Nasal Examination, Nasal Endoscopy Intervention Description: Participants undergo taste and smell testing to assess
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Istanbul Training and Research Hospital
Pancreatic Neoplasm
Core Biopsy Endo Sonography Study Evaluation of the Significance of the Pro-core® Needle
The study is designed to evaluate the diagnostic accuracy of a new designed endoscopic ultrasonography (EUS) Core biopsy aspiration needle in comparison to a conventional EUS aspiration needle in GI-tumors.
- Trial name
- COS (NCT02181140)
- Testing
- EUS guided FNA and fine needle punction
- Where
- Germany
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Anxiety, Preoperative Anxiety
Impact of the Information Leaflet on the Anesthesia Knowledge and Anxiety Levels of Children and Parents
The study includes applying a questionnaire to each child and their parents who applied to the anesthesia outpatient clinic for the gastroenterological endoscopic procedure.
- Conditions
- Anxiety, Preoperative Anxiety, Pediatric Anesthesia
- Trial name
- NCT05221671
- Testing
- information leaflet
- Where
- Turkey (Türkiye)
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Gazi University
Obesity, Weight Change Trajectory
Evaluation of the Safety and Efficacy of Revita® DMR on Body Weight Maintenance in Subjects With Obesity Who Have Achieved at Least 15% Weight Loss on Tirzepatide
Fractyl is evaluating Revita Duodenal Mucosal Resurfacing (DMR) in the REMAIN-1 pivotal study, which is designed to include two cohorts - an open label cohort referred to as REVEAL-1, and a randomized cohort, which includes both…
- Conditions
- Obesity, Weight Change Trajectory, Weight Change, Body
- Trial name
- REMAIN-1 (NCT06484114)
- Testing
- Revita Duodenal Mucosal Resurfacing (DMR)
- Where
- 32 sites in United States
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Fractyl Health Inc.
Rhinosinusitis
Effect of Hot Saline Irrigation on the Operative Field During Endoscopic Sinus Surgery
Control of bleeding is very important during endoscopic sinus surgery. Saline heated up to 50°C causes dilatation of vessels and edema without nasal mucosa necrosis.
- Trial name
- NCT06343493
- Testing
- Normal saline heated up to 50 °C
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Medical College
Hypoxemia, Airway Management
Multifunctional Oropharyngeal Airway and Hypoxemia in Sedated GI Endoscopy: A Multicenter RCT
This multicenter, prospective, randomized controlled trial aims to evaluate whether a novel multifunctional oropharyngeal airway (MOPA) reduces the incidence of hypoxemia in 1,518 adult patients (ASA I-II, aged 18-80 years)…
- Trial name
- NCT07623863
- Testing
- Novel Multifunctional Oropharyngeal Airway
- Volunteers
- 1,518 people, healthy volunteers welcome
- Sponsor
- Qianfoshan Hospital
Artificial Intelligence, Enteroscope
A Clinical Trial of the Effectiveness and Safety of Software Assisting Diagnose the Intestinal Polyp Digestive Endoscopy by Analysis of Colonoscopy Medical Images From Electronic Digestive Endoscopy Equipment
A clinical trial of the effectiveness and safety of intestinal polyp digestive endoscopy-assisted diagnosis software used in the analysis of colonoscopy medical images generated by electronic digestive endoscopy equipment.
- Conditions
- Artificial Intelligence, Enteroscope, Intestinal Polyposis, Adenomatous
- Trial name
- NCT05687318
- Testing
- DeFrame
- Where
- China
- Volunteers
- 337 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Upper Gastrointestinal Hemorrhage
Standard Endoscopic Hemostasis Versus OVESCO Severe Non-variceal UGI Hemorrhage
The primary specific aim is to perform a randomized controlled trial (RCT) to compare 30 day rebleed rates and other clinical outcomes of patients with severe, non-variceal upper GI hemorrhage (NVUGIH) - ulcers and Dieulafoy's…
- Trial name
- NCT03065465
- Testing
- Over-the-scope hemoclipping device, Standard endoscopic treatment
- Where
- 2 sites in United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- CURE Digestive Diseases Research Center
Autoimmune Pancreatitis
Study on AI-assisted Multimodal Diagnosis System of Autoimmune Pancreatitis
The existing comprehensive diagnostic system for autoimmune pancreatitis (AIP) is complex, with multidimensional clinical information including morphological changes and a lack of specific biomarkers.
- Trial name
- NCT06369909
- Testing
- EUS-FNA
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Capsule Endoscopy
Real-Time Identification System of Magnetically Controlled Capsule Endoscopy Using Artificial Intelligence
The aim of this study is to evaluate the performance of real-time auxiliary system based on artificial intelligence algorithm in lesion detection and quality control in magnetically controlled capsule endoscopy.
- Trial name
- NCT04203264
- Testing
- Real-time artificial intelligence identification system
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Sinusitis
Gold Laser Vs. Micro-Debriders for Functional Endoscopic Sinus Surgery
Sinusitis is a common medical problem, which significantly decreases patients' quality of life (QOL). Patients may have symptoms such as headaches, sinus pressure, nasal congestion and drainage, decreased sense of smell, and…
- Trial name
- NCT02900794
- Testing
- Gold Laser, Microdebridement
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Esophageal Squamous Cell Carcinoma
Endoscopic Screening on Esophageal Cancer
Importance: There are no global screening recommendations for esophageal squamous cell carcinoma (ESCC). Endoscopic screening has been investigated in high incidence areas of China since 1970's.
- Trial name
- NCT02094105
- Testing
- Endoscopy examination with iodine staining
- Where
- China
- Volunteers
- 45,386 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences