Clinical trials: Endoscopy
Anticoagulant Disorders
Management of Direct Oral Anti-Coagulants (DOACs) for Gastrointestinal Endoscopy Procedures
The use of Direct Oral Anti-Coagulants (DOACs) is expanding, but their proper management in patients undergoing endoscopic procedures is still not completely clear. Current European guidelines are based on weak data.
- Trial name
- NCT02734316
- Testing
- endoscopic procedure
- Where
- Italy
- Volunteers
- 531 people, healthy volunteers welcome
- Sponsor
- Valduce Hospital
Healthy
Development of Applications of PillCam™ Endoscopy and Patency Systems and Clinical Evaluation of Their Performance in Healthy Volunteers ("HEIGHT" Study)
This is a feasibility, prospective, single center, open label, uncontrolled clinical study, to evaluate the safety and preliminary efficacy of the different R\&D changes made and implemented in the existing PillCam Capsule…
- Trial name
- NCT03301909
- Testing
- PillCam™ Endoscopy System, Bowel prep combination
- Where
- Israel
- Volunteers
- 694 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Colonoscopy, Colorectal Cancer Screening
Triton 1.5 Robotic System for Diagnostic Colonoscopy
This study is a prospective, single-arm, non-randomized, single-site study, focused on evaluating the safety and efficacy of the Triton 1.5 System in diagnostic and basic therapeutic colonoscopy.
- Trial name
- CARE II (NCT07606963)
- Testing
- Diagnostic Test: Diagnostic Colonoscopy
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Neptune Medical
Colonic Adenomas
Comparison Between White Light Endoscopy and Bright Narrow Band Imaging in Diagnosis Colonic Adenomas.
Removal of colorectal adenomas prevents the occurence of colorectal cancers. The use of chromo-endoscopy has been shown to improve the detection of flat adenomas.
- Trial name
- WLEvB-NBI (NCT01737567)
- Testing
- Bright Narrow Band Imaging., White Light Endoscopy
- Where
- Australia
- Volunteers
- healthy volunteers welcome
- Sponsor
- Professor Michael Bourke
Informed Consent Process
Comparing AI Role-Play and Peer Role-Play for Informed Consent Training in Endoscopy: A Randomized Control Trial
The goal of this randomized controlled trial is to find out whether AI-based role play is effective in teaching healthcare trainees how to obtain informed consent from patients for endoscopic procedures.
- Trial name
- NCT07069504
- Testing
- AI-based role play, Peer role play
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Obesity, Hypertension
Multicenter Endoscopic Sleeve Gastrectomy (ESG) Trial (MERIT Trial)
Endoscopic Sleeve Gastroplasty (ESG) is an endoscopic minimally invasive weight loss procedure where a commercially available, FDA approved, full-thickness endoscopic suturing device (Overstitch; Apollo Endosurgery, Austin, TX)…
- Conditions
- Obesity, Hypertension, Diabetes Mellitus, Type 2
- Trial name
- NCT03406975
- Testing
- Overstitch Endoscopic Suture System, Lifestyle Intervention
- Where
- 9 sites in United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Compare Ecchymosis and Edema for Fibrin Sealant and no Fibrin Sealant
Efficacy and Safety of Fibrin Sealant (FS) VH S/D-APR for Hemostasis and Wound Healing in Endoscopic Browlift
The primary objective is to evaluate the safety and efficacy of Artiss (Fibrin Sealant) in reducing the incidence of early postoperative bruising and swelling.
- Trial name
- NCT01320514
- Testing
- Fibrin Sealant (Artiss)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Nguyen, Davis B., M.D.
Neural Tube Defects, Spina Bifida
In-Utero Endoscopic Correction of Spina Bifida
The purpose of this study is to evaluate the feasibility and effectiveness of performing fetoscopic surgical correction of fetal spina bifida.
- Conditions
- Neural Tube Defects, Spina Bifida, Myelomeningocele
- Trial name
- NCT04362592
- Testing
- In Utero Endoscopic Correction of Myelomeningocele IDE - Percutaneous Technique, In Utero Endoscopic Correction of Myelomeningocele IDE - Laparotomy/Uterine Exteriorization Technique
- Where
- 2 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Driving
Accessing the Driving Skills After the Endoscopy of Intravenous Anesthesia by Driving Simulator
The purpose of this study is to assess the driving and cognitive ability of gastrointestinal endoscopy patients at different time points after intravenous anesthesia (propofol for example), and to explore whether the driving and…
- Trial name
- NCT02280148
- Testing
- Endoscopy of Intravenous Anesthesia, Driving Simulator, Propofol
- Where
- China
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Anesthesia Morbidity
HIFLO ENDO-High Flow Nasal Cannula in GI Endoscopy
Millions of patients undergo upper GI endoscopy in the United States each year. A large number of these patients have anesthesia to assist with their comfort during the procedure.
- Trial name
- NCT03028688
- Testing
- High flow nasal cannula oxygen
- Where
- United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Ulnar Nerve Compression, Cubital Tunnel
Sonographic Examination Cubital Tunnel Release
The investigators want to compare changes in cross-sectional area (CSA) of the ulnar nerve at the elbow after open release or endoscopic release.
- Trial name
- SPECTRE (NCT02739945)
- Testing
- Cubital tunnel release
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Gastric Cancer
Study on the Effectiveness of Gastroscope Operation Quality Control Based on Artificial Intelligence Technology
This study aims to construct a real-time quality monitoring system based on artificial intelligence technology.
- Trial name
- NCT04384575
- Testing
- blind spots
- Where
- China
- Volunteers
- 1,570 people, healthy volunteers welcome
- Sponsor
- Peking University
Healthy Subjects
JetTouch Injection System to Deliver Saline Into the Bladder Wall of Healthy Volunteers
This research study is being done to see how well the JetTouch Needle-Free Endoscopic Injection System is able to deliver a solution safely into the bladder wall.
- Trial name
- NCT01862601
- Testing
- JetTouch Needle-free injection system
- Where
- 2 sites in United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- American Medical Systems
Gastric Lesion, Gastritis
Capsule Gastric Endoscopy for Gastric Disease Screening in Simulated Home Scenarios
The goal of this clinical trial is to evaluate the diagnostic accuracy of the AI-integrated Capsule Gastroscopy (ACG) system in simulated home-use conditions for detecting upper gastrointestinal (UGI) abnormalities.
- Conditions
- Gastric Lesion, Gastritis, Upper Gastrointestinal Bleeding (UGIB), Gastric Dysplasia
- Trial name
- NCT06848400
- Testing
- AI-integrated Capsule Gastroscopy (ACG) examination, Electronic gastroduodenoscopy (EGD) examination
- Where
- 12 sites in China, Hong Kong and 1 more
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Percutaneous Endoscopic Gastrostomy (PEG), Training
Training Program for PEG Caregivers: A Structured Intervention Study
This study aims to develop and evaluate a structured education program and a mobile application to support caregivers of patients receiving enteral nutrition via percutaneous endoscopic gastrostomy (PEG).
- Conditions
- Percutaneous Endoscopic Gastrostomy (PEG), Training, Caregiver Burden, Nutritional Support
- Trial name
- PEG-EDU (NCT07074301)
- Testing
- Caregiver Training Program
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Koç University
Anxiety, Preoperative Anxiety
Impact of the Information Leaflet on the Anesthesia Knowledge and Anxiety Levels of Children and Parents
The study includes applying a questionnaire to each child and their parents who applied to the anesthesia outpatient clinic for the gastroenterological endoscopic procedure.
- Conditions
- Anxiety, Preoperative Anxiety, Pediatric Anesthesia
- Trial name
- NCT05221671
- Testing
- information leaflet
- Where
- Turkey (Türkiye)
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Gazi University
Endoscopy, Digestive System
The Impact of Artificial Intelligence (AI) on the Quality of Upper Gastrointestinal (GI) Endoscopy
Oesophageal and gastric cancer are two of the six less survivable cancers, responsible for half of cancer deaths and a quarter of cancer cases.
- Trial name
- NCT05845463
- Testing
- Cerebro endoscopy quality control tool
- Where
- United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sandwell & West Birmingham Hospitals NHS Trust
Pancreatic Neoplasm
Core Biopsy Endo Sonography Study Evaluation of the Significance of the Pro-core® Needle
The study is designed to evaluate the diagnostic accuracy of a new designed endoscopic ultrasonography (EUS) Core biopsy aspiration needle in comparison to a conventional EUS aspiration needle in GI-tumors.
- Trial name
- COS (NCT02181140)
- Testing
- EUS guided FNA and fine needle punction
- Where
- Germany
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Colonic Polyp
A Technique Using EBL for Removal of Pedunculated Colon Polyps
Bleeding is the most common complication associated with polypectomy of large pedunculated colonic polyp. Although several techniques have been developed to minimize bleeding, none of these methods has become the gold standard.
- Trial name
- NCT04123080
- Testing
- Endoscopic band ligation assisted polypectomy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Uijeongbu St. Mary Hospital
Capsule Endoscopy
MCE Direct Visualization of Drug Behavior in Upper-gastrointestinal Tract
The investigators aim to explore the feasibility of MCE in direct, real-time visualization of drug behavior in upper-gastrointestinal tract, which presented by the adhesion, distribution, and dissipation characteristics of dyed…
- Trial name
- NCT04327869
- Testing
- Magnetically controlled capsule endoscopy
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital