Clinical trials: Endoscopy, open to volunteers
Depth of Anesthesia, Nociception
Anesthesia Induction Scheme for Painless Gastrointestinal Endoscopy Patients Based on Nociceptive Stimulation Monitoring
Nociception is the encoding and processing of noxious stimulation and is considered an objective indicator for monitoring pain. Currently, a new clinically-applied medical-engineering integrated monitoring device for noxious…
- Conditions
- Depth of Anesthesia, Nociception, Painless Gastrointestinal Endoscopy
- Trial name
- NCT06604156
- Testing
- EEG monitoring
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Min Su
Obesity & Overweight
ERCG vs Intensive Lifestyle Intervention for Weight Regain After GLP-1 RA Discontinuation
This randomized controlled trial aims to evaluate the efficacy and safety of Endoscopic Radial Compression Gastroplasty (ERCG) in mitigating weight regain following discontinuation of glucagon-like peptide-1 receptor agonists…
- Trial name
- NCT07908823
- Testing
- Endoscopic Radial Compression Gastroplasty (ERCG), Intensive Lifestyle Intervention (ILI)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Esophageal and Gastric Varices
Evaluation of Endoscopic Treatment Effect Based on HVPG
This study aims to evaluate the endoscopic treatment effect and related influencing factors of patients with esophageal and gastric varices based on HVPG.
- Trial name
- NCT06863519
- Testing
- Endoscopic treatment
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Biliary Tract Injuries
Endoscopic Treatment of Post Surgical Biliary Tract Injury
The objective of this study is to determine the technical and clinical success rate of endoscopic treatment in a population presenting only with iatrogenic injuries of the bile ducts, excluding the cystic duct.
- Trial name
- EpSB (NCT07345936)
- Where
- France
- Volunteers
- 220 people
- Sponsor
- University Hospital, Strasbourg, France
Cervical Disease
Comparison of High-Definition Electronic Magnifying Endoscopy With Image-Enhanced Technology Versus Colposcopy in the Detection of Cervical and Vaginal Lesions
1. Primary Objective: To compare the diagnostic accuracy of high-definition electronic magnifying endoscopy combined with image-enhanced technology versus colposcopy for cervical and vaginal lesions. 2.
- Trial name
- NCT07508072
- Testing
- high-definition electronic magnifying endoscopy combined with image-enhanced technology
- Volunteers
- 270 people
- Sponsor
- West China Second University Hospital
Portal Hypertension Related to Cirrhosis
EUS-guided Response Assessment to NSBB
The goal of this clinical trial is to learn if endoscopic ultrasound (EUS)-guided portal pressure measurement can determine the treatment response to non-selective beta-blockers (NSBB) in patients with cirrhosis and clinically…
- Trial name
- NCT06513195
- Testing
- endoscopic ultrasound-guided portal pressure measurement
- Where
- Belgium
- Volunteers
- 24 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Colorectal Neoplasms
Follow-up After Oncological Resection by Endoscopic Colorectal ESD (Endoscopic Submucosal Dissection)
Colorectal cancer is a common and leading cause of death. Pre-cancerous lesions, as well as some so-called superficial cancers, can be resected via endoscopy.
- Trial name
- FORCE (NCT07871227)
- Testing
- Surgery, Radiochimiotherapy
- Where
- 14 sites in France
- Volunteers
- 1,200 people
- Sponsor
- University Hospital, Bordeaux
Gastro Esophageal Reflux
Observational Registry of Transoral Incisionless Fundoplication (TIF) for Gastroesophageal Reflux Disease (GERD)
This observational registry aims to: 1) record the TIF interventions in patients with esophageal or extra-esophageal symptoms; 2) to monitor the therapy response through the clinical experience in terms of effect on the use and…
- Trial name
- TIF/2021 (NCT05066594)
- Testing
- Transoral incisionless fundoplication
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS San Raffaele
Tumor, Solid
Phase II Study of Intensity Modulated Radiotherapy in Dose Painting for Sinus Carcinomas After Endoscopic Surgery
The patient is randomized to one of the following groups: Experimental group: Radiotherapy in painting dose on histoscannographic mapping Control group: standard pan-sinus radiotherapy
- Trial name
- SinocaRT (NCT05943119)
- Testing
- Radiotherapy in painting dose on histoscannographic mapping, Standard pan-sinusal Radiotherapy
- Where
- 3 sites in France
- Volunteers
- 52 people
- Sponsor
- Centre Francois Baclesse
Endoscopy, Digestive System, GLP1-R-related Disease
Evaluate the Detection of Retained Gastric Contents and Assess Safety Using the Flower Capsule Endoscopy in Healthy Individuals and GLP-1 Receptor Agonist Users
Clinical Study Overview Feasibility Study Plan (Study 1: Healthy Participants) Study 1- Confirming Flower capsule performance characteristics in detection of retained gastric contents greater than 1.5mL/kg in Healthy volunteers…
- Trial name
- NCT06927401
- Testing
- Flower
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Acute Pancreatitis (AP)
Endoscopic Pancreatic Duct Stent Placement Versus Conventional Approach in the Treatment of Early Phase Acute Pancreatitis
The planned multicenter randomized study is aimed to assess the efficacy and safety of endoscopic pancreatic duct stenting in adult patients with acute pancreatitis.
- Trial name
- NCT07093996
- Testing
- Endoscopic pancreatic duct stent placement, Conventional treatment of acute pancreatitis in early phase
- Where
- 7 sites in China, Russia
- Volunteers
- 200 people
- Sponsor
- Almazov National Medical Research Centre
Esophageal Achalasia, Esophageal Motility Disorders
POEM Versus Laparoscopic Heller Myotomy With Dor Fundoplication for Esophageal Achalasia
Achalasia is a disorder of the esophagus in which the muscular valve between the esophagus and the stomach fails to relax, and the body of the esophagus loses its normal coordinated squeezing movement.
- Conditions
- Esophageal Achalasia, Esophageal Motility Disorders, Gastroesophageal Reflux
- Trial name
- POEM-HD (NCT07814027)
- Testing
- Peroral endoscopic myotomy, Laparoscopic Heller myotomy with Dor fundoplication
- Where
- Egypt
- Volunteers
- 220 people
- Sponsor
- Minia University
Discogenic Low Back Pain, Intervertebral Disc Degeneration
RenewDisc Trial: Endoscopic Discectomy and Autologous Stem Cell Therapy for Discogenic Low Back Pain
he RenewDisc Trial is a prospective observational clinical study evaluating outcomes in patients with confirmed discogenic low back pain who undergo standard clinical care using endoscopic spine procedures.
- Conditions
- Discogenic Low Back Pain, Intervertebral Disc Degeneration, Lumbar Disc Disease, Chronic Low Back Pain
- Trial name
- RENEWDISC (NCT07338877)
- Where
- Slovakia
- Volunteers
- 120 people
- Sponsor
- EPC Education s.r.o.
Portal Hypertension, Gastroesophageal Varices Hemorrhage
Optimizing Endoscopic and Interventional Treatment for Portal Hypertensive Bleeding
This study aims to evaluate the impact of high-risk factors-such as elevated portal venous pressure, concurrent large extra-luminal vessels, portal vein thrombosis, and prominent portosystemic shunts-on the efficacy of endoscopic…
- Conditions
- Portal Hypertension, Gastroesophageal Varices Hemorrhage, Gastric Varices, Esophageal Varices
- Trial name
- NCT07502729
- Volunteers
- 1,066 people
- Sponsor
- Shanghai Zhongshan Hospital
Gastrointestinal Bleeding
Capsule Endoscopy in GI Bleeding: A Retrospective Study
The goal of this observational study is to evaluate the diagnostic value and safety of capsule endoscopy in patients with gastrointestinal bleeding.
- Trial name
- NCT07481591
- Testing
- capsule endoscopy
- Volunteers
- 350 people
- Sponsor
- Changhai Hospital
Endoscopic Sleeve Gastroplasty, Obesity
Endoscopic Sleeve Gastroplasty (ESG) for the Treatment of Obesity
The purpose of this study is to evaluate endoscopic sleeve gastroplasty (ESG) for the treatment of obesity. The ESG procedure is an U.S.
- Trial name
- NCT06339320
- Testing
- Endoscopic Sleeve Gastroplasty (ESG), Apollo OverStitch endoscopic suturing device
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- The Methodist Hospital Research Institute
Colon Polyp
A First-in-human Clinical Trial Evaluating a Novel Colonic Intraluminal Endoscopic Support Structure (CIESS)
The aim of the first-in-human clinical trial is to evaluate the feasibility of performing colonoscopic polypectomy with a novel colonic intraluminal endoscopic support structure (CIESS) in-situ
- Trial name
- NCT07311590
- Testing
- Colonic Intraluminal Endoscopic Support Structure
- Volunteers
- 4 people
- Sponsor
- JurongHealth
Sedation During GI Endoscopy
Comparison Between Two Drugs in Sedation of Upper GI Endoscopy
The goal of this clinical trial is to compare time of sedation between two drugs administered to patients undergoing upper gastrointestinal endoscopy Primary outcome : Time of sedation : is the time to reach sedation score of 5…
- Trial name
- NCT07423676
- Volunteers
- 52 people
- Sponsor
- Zagazig University
Fistula Repair
Endoscopic Injection of Autologous, Activated and Emulsified Fat in Chronic Fistulas of the Gastrointestinal Tract and Pelvic Organs
Fistulas are defined as pathologic communications between two epithelialized surfaces and represent a complex nosologic entity that often exposes the patient to life-threatening or disabling sequelae.
- Trial name
- ERG (NCT06930079)
- Where
- Italy
- Volunteers
- 43 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Diabetes Mellitus, Type 2, Obesity
Endoscopic Sutured Gastroplasty with Endomina® Device Versus Standard of Care in Patients with Type 2 Diabetes and Class I Obesity: a Multi-center, Randomized Controlled Trial
The primary objective of this study is to assess the efficacy of endoscopic gastric reduction with the endomina® device, in combination with standard of care, compared to standard of care alone, on the remission of diabetes 24…
- Trial name
- ESTIME (NCT05516576)
- Testing
- endomina®
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Grenoble