Clinical trials: Endovascular Treatment
Acute Ischemic Stroke
The Improve Acute Reperfusion Treatment Quality for Ischemic Stroke Through Spatiotemporal Computing Thecnology in China
This study intends to construct the goal-oriented integrated intervention model through the intelligent bracelet automatic positioning and feedback system based spatiotemporal computing technology (FAST model) to promote the…
- Trial name
- IMPROVE-II (NCT06330051)
- Testing
- The goal-oriented integrated intervention model through the intelligent bracelet automatic positioning and feedback system based spatiotemporal computing technology (FAST model)
- Where
- China
- Volunteers
- 2,219 people
- Sponsor
- Beijing Tiantan Hospital
Ischemic Stroke
SMART-EST(Specialized Multi-center Attributed Registry of sTroke - EndovaScular or Thrombolytic Therapy)
Use of intravenous(IV) thrombolysis and intra-arterial(IA) recanalization treatment has been rapidly increasing, However, despite of the treatment, recanalization rates are 22.6 - 70% and only 30-50% of patients show meaningful…
- Trial name
- NCT04066556
- Testing
- Brain CT imaging
- Where
- South Korea
- Volunteers
- 5,000 people
- Sponsor
- Yonsei University
Brain Infarction
Flying Intervention Team for Endovascular Treatment of Acute Ischemic Stroke in Rural Areas
The aim of this study is to compare time delay and safety parameters of stroke patients initially admitted to a rural primary stroke center (PSC) who receive endovascular treatment (EVT) by a Flying Intervention Team with…
- Trial name
- FIT (NCT04270513)
- Testing
- Endovascular treatment by Flying Intervention Team
- Where
- Germany
- Volunteers
- 477 people
- Sponsor
- Munich Municipal Hospital
Intracranial Aneurysm
Flow Diversion in Intracranial Aneurysm Treatment
Flow diverters are a recent addition to the range of endovascular devices now available for the treatment of intracranial aneurysms.
- Trial name
- FIAT (NCT01349582)
- Testing
- flow diversion, conservative management, endovascular coiling
- Where
- 3 sites in Canada
- Volunteers
- 323 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Abdominal Aortic Aneurysms (AAA)
Use of Artificial Intelligence to Predict Complications Following Abdominal Aortic Surgery
Abdominal aortic aneurysm, a condition characterised by an increase in the diameter of the aorta, can be treated either surgically or endovascularly.
- Trial name
- AORTAPREDICT (NCT06884397)
- Testing
- Abdominal aortic endoprosthesis
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis
Hydrocephalus, Hydrocephalus, Communicating
Pilot Study to Evaluate the CereVasc® EShunt® System in the Treatment of Communicating Hydrocephalus
The purpose of this study will be to evaluate a novel, minimally invasive method of treating hydrocephalus in adults. The eShunt® System includes a proprietary eShunt® Delivery System and the eShunt® Implant, a permanent implant…
- Trial name
- NCT05501002
- Testing
- eShunt® Implant
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- CereVasc Inc
Stroke
Berlin PRehospital Or Usual Delivery of Acute Stroke Care
Prehospital stroke care in specialized ambulances increases thrombolysis rates, reduces alarm-to-treatment times, and improves prehospital triage. Preliminary analyses suggest cost-effectiveness.
- Trial name
- B_PROUD (NCT02869386)
- Testing
- STEMO, Regular care
- Where
- Germany
- Volunteers
- 1,500 people
- Sponsor
- Charite University, Berlin, Germany
Steno-occlusive Desease of Femoro-popliteal Arterial Segment
Remote Endarterectomy and Endovascular Treatments in Patients With the Femoral Artery Occlusive Disease
Comparison of two methods for revascularization of the superficial femoral artery: remote endarterectomy vs. stenting of the superficial femoral artery cin patients with steno-occlusive lesion of the femoro-popliteal segment of…
- Trial name
- NCT02948166
- Testing
- Angioplasty with stenting of the femoral artery, Open surgery
- Where
- Russia
- Volunteers
- 174 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Aortic Aneurysm, Abdominal
Post-Approval Trial of the Talent™ Abdominal Stent Graft to Treat Aortic Aneurysms
The purpose of this study is to examine, through the endpoints established in this protocol, the long-term safety and effectiveness of the Talent Abdominal Stent Graft System, in a post-approval environment.
- Trial name
- VITALITY (NCT00816062)
- Testing
- Talent Abdominal Stent Graft
- Where
- 18 sites in United States
- Volunteers
- 94 people
- Sponsor
- Medtronic Cardiovascular
Ischemic Stroke
Safety and Optimal Neuroprotection of neu2000 in Ischemic Stroke With Endovascular reCanalizion (SONIC)
Efficacy and safety of Neu2000, a multi-target drug designed to prevent both NMDA receptor-mediated excitotoxicity and free radical toxicity, will be investigated in acute ischemic stroke patients receiving endovascular treatment…
- Trial name
- SONIC (NCT02831088)
- Testing
- Neu2000KWL High-does group, Neu2000KWL Low-does group
- Where
- 6 sites in South Korea
- Volunteers
- 210 people
- Sponsor
- GNT Pharma
Aortic Aneurysm, Thoracic, Penetrating Aortic Ulcers (PAUs)
Evaluation of Thoraflex in the Treatment of Aneurysm or Penetrating Ulcer of the Descending Thoracic Aorta
ThoraflexTM is designed for the treatment of aneurysm or penetrating ulcer of the descending thoracic aorta. Each system is advanced from a transfemoral or transiliac approach over a 0.035" guidewire and positioned under…
- Trial name
- NCT01357590
- Testing
- Thoracic Endovascular Stent Graft System (ThoraflexTM)
- Where
- 28 sites in Belgium, Canada and 5 more
- Sponsor
- Vascutek Ltd.
Ascending Aortic Dissection
Retrograde Ascending Dissection: Intraluminal Aortic Therapy
This study is a single-arm, open-label, multi-center clinical trial evaluating the safety and efficacy of endovascular treatment for retrograde dissection involving the ascending aorta that is not suitable for open surgery.
- Trial name
- RADIAL (NCT07405242)
- Testing
- Endovascular treatment of aortic dissection (stent implantation)
- Where
- China
- Volunteers
- 149 people
- Sponsor
- Ruijin Hospital
Intracranial Aneurysm, Subarachnoid Hemorrhage
PRET: Patients Prone to Recurrence After Endovascular Treatment
The PRET study aims at comparing two types of coils used in the endovascular treatment of intracranial aneurysms. The first type made of platinum has been used for more than 15 years.
- Trial name
- PRET (NCT00626912)
- Testing
- endovascular coil embolization
- Where
- 32 sites in United States, Canada and 4 more
- Volunteers
- 447 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Peripheral Vascular Diseases
Individual Patient Data Analysis of Viabahn for Peripheral Arterial Disease
To evaluate the effectiveness of the VSX device in pre-determined patient populations to understand the patient characteristics that impact outcomes.
- Trial name
- Insight-VSX (NCT05459818)
- Testing
- Viabahn implanted
- Where
- Netherlands
- Volunteers
- 977 people
- Sponsor
- Rijnstate Hospital
Acute Ischemic Stroke
Sedation vs. Intubation for Endovascular Stroke TreAtment
Sedation vs Intubation for Endovascular Stroke TreAtment Trial (SIESTA) is a prospective, randomised controlled, monocentric, two-armed, comparative trial.
- Trial name
- SIESTA (NCT02126085)
- Testing
- Endovascular recanalisation
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- University Hospital Heidelberg
Peripheral Arterial Disease, Lower Extremity Arterial Disease
EverFlex Post Approval Study
This post-approval study is designed to confirm the long-term safety and effectiveness of the EverFlex™ Self-Expanding Stent System for the treatment of atherosclerotic superficial femoral artery (SFA) and proximal popliteal…
- Trial name
- DURABILITY PAS (NCT01680835)
- Testing
- EverFlex™ Self-Expanding Peripheral Stent System
- Where
- 23 sites in United States
- Volunteers
- 108 people
- Sponsor
- Medtronic Endovascular
Acute Ischemic Stroke
Adjunctive Use of Intra-Arterial TNK and Albumin Following Thrombectomy
The purpose of this study is to investigate the feasibility and efficacy of intra-arterial TNK and albumin for patients with acute ischemic stroke after successful thrombectomy and whether there is a synergistic effect between…
- Trial name
- NCT06113848
- Testing
- Intra-Arterial TNK and Albumin, Intra-Arterial TNK, Intra-Arterial Albumin
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Tianjin Huanhu Hospital
Acute Stroke
Endovascular Revascularization With Solitaire Device Versus Best Medical Therapy in Anterior Circulation Stroke Within 8 Hours
To evaluate the hypothesis that mechanical embolectomy with the Solitaire FR device is superior to medical management alone in achieving favorable outcome in the distribution of the modified Rankin Scale scores at 90 days in…
- Trial name
- REVASCAT (NCT01692379)
- Testing
- Solitaire FR device, Medical treatment
- Where
- 4 sites in Spain
- Volunteers
- 206 people
- Sponsor
- Fundacio Ictus Malaltia Vascular
Stroke, Endovascular Treatment
Endovascular treatmenT for Acute Ischemic Stroke in China
This is a retrospective real world registry study, aiming to explore the effectiveness and safety of endovascular treatment of acute ischemic stroke in a Chinese population.
- Trial name
- DETECT-China (NCT04752735)
- Testing
- endovascular treatment
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- General Hospital of Shenyang Military Region
Stroke Ischemic, Medium Vessel Occlusions
Advancing Reperfusion Therapy for Ischemic Stroke: Perfusion-guided Endovascular Intervention for Medium Vessel Occlusion Therapy
The investigators initiated a multicenter, prospective, randomized, open label, blinded-endpoint (PROBE) controlled trial to evaluate the efficacy and safety of perfusion-guided endovascular treatment (EVT) compared to standard…
- Trial name
- ARTS-PIVOT (NCT07323368)
- Testing
- Endovascular treatment, Best medical treatment (BMT)
- Where
- 6 sites in China
- Volunteers
- 568 people
- Sponsor
- Beijing Tiantan Hospital