Clinical trials: Enhanced Recovery
Knee Injuries, Knee Osteoarthritis
Blood-Flow Restriction Exercise Following a Knee Replacement
This study will determine the safety and efficacy of using blood-flow restriction exercise enhancement (B-FREE) to overcome persistent quadriceps muscle weakness that occurs following a total knee replacement (TKR).
- Conditions
- Knee Injuries, Knee Osteoarthritis, Knee Arthritis
- Trial name
- NCT04018638
- Testing
- B-FREE
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Michigan Technological University
Gynecologic Surgical Procedures, Enhanced Recovery After Surgery
Prehabilitation Plus ERAS vs ERAS in Gynecological Surgery
Prospective, interventionist, controlled and randomized study to test the effectiveness of multimodal prehabilitation protocol in patients who will undergo gynecological surgery.
- Trial name
- NCT04505111
- Testing
- Prehabilitation Program + Enhanced Recovery After Surgery, Enhanced Recovery After Surgery
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Instituto Brasileiro de Controle do Cancer
Opioid Use, Kidney Diseases
Enhanced Recovery After Surgery in Kidney Transplant Donors
Enhanced recovery after surgery (ERAS) pathways are designed to optimize perioperative management, improving patient outcomes and satisfaction through multimodal techniques.
- Conditions
- Opioid Use, Kidney Diseases, Pain, Postoperative, Postoperative Complications
- Trial name
- NCT04110080
- Testing
- multimodal pain management, goal directed fluid management, preoperative carbohydrate loading
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Preoperative Care, Anxiety
Use of Maltodextrins in the ERAS Preoperative Fasting Protocol in Pediatric Surgery
This monocentric prospective randomized controlled pilot study aims to evaluate the effectiveness of preoperative maltodextrin administration within an Enhanced Recovery After Surgery (ERAS) protocol in pediatric surgical…
- Conditions
- Preoperative Care, Anxiety, Pediatric Surgery
- Trial name
- ERAS-MALTO (NCT07686029)
- Testing
- Maltodextrin Clear Liquid, Non-Sugared Clear Liquid
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
ERAS Protocol, Esophagectomy
Enhanced Recovery in Esophageal Surgery
Esophageal surgery remains the main treatment for esophageal cancer. Despite constant improvements, morbidity of esophagectomy remains high.
- Trial name
- NCT05856253
- Testing
- Enhanced recovery program
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Opioid Free Anesthesia, Opioid Based Anesthesia
Intraoperative Infusion of Dexmedetomidine Versus Lidocaine or Magnesium Sulphate for Enhanced Quality of Recovery After Spine Surgery Fixation
Thoracolumbar fixation is a major spine surgery; it is performed to stabilize the spine after trauma, deformity or advanced degenerative disease.
- Conditions
- Opioid Free Anesthesia, Opioid Based Anesthesia, Spine Fixation Surgeries, Opiod-Related Disorders
- Trial name
- NCT07843953
- Testing
- Group ( L): LICOCAINE, GROUP Dexmedetomidine, Group M: Magnesium sulphate
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Anesthesia
Enhanced Recovery After Surgery (ERAS) Total Knee Replacement (TKR) With a Transitional Pain Service
A comparison of two anesthetic techniques for total knee replacements: (1) Peri-Articular Injection (PAI), local infiltration between the popliteal artery and capsule of the knee block (IPACK) and single-shot adductor canal block…
- Trial name
- EKAT-TeleTPS (NCT03747146)
- Testing
- Continuous Adductor Canal Catheter (ACC)
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Spinal Cord Injury
AI-Powered Closed-Loop Multielectrode Transcutaneous Spinal Cord Stimulation: Real-Time Adjustments for Enhanced Motor Recovery in Spinal Cord Injury (AIM RECOVER)
Spinal cord injury (SCI) often results in persistent motor deficits that are inadequately addressed by conventional rehabilitation.
- Trial name
- AIM RECOVER (NCT07452133)
- Testing
- Dynamic stimulation, Static stimulation
- Where
- Singapore
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Breast Cancer, Gynecologic Cancer
Mobile App Postoperative Home Monitoring After Enhanced Recovery Oncologic Surgery
This study will assess whether the implementation of a combination of ERAS (Enhanced Recovery After Surgery) protocols and postoperative followup via a smartphone app can offer 1) improved patient satisfaction, 2) virtual patient…
- Trial name
- ERAS-OncoRe (NCT03456167)
- Testing
- RecoverWell mobile app for follow-up care
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Alberta Health Services, Calgary
Chronic Stroke-related Upper-extremity Motor Impairment, Motor Module-guided Rehabilitation Targeting Impaired Intermuscular Coordination and Motor Recovery
Neuro-Intermuscular Coordination Enhancement (NICE) Rehabilitation Through Human-Machine Interaction in Chronic Stroke
The objective of this study is to develop Neuro-Intermuscular Coordination Enhancement (NICE) rehabilitation, a novel neuromuscular control signal-guided strategy that visually guides stroke patients to individually activate…
- Trial name
- NICE (NCT07531264)
- Testing
- Neuromuscular coordination enhancement (NICE) intervention, EMG Amplitude Biofeedback Exercise
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Houston
Living Liver and Kidney Donors
Living Organ Donor Recovery Enhancement Program
The purpose of the study is to test if using these living donor-specific pre-transplant resources would lead to a better and faster recovery post-transplant.
- Trial name
- NCT03865264
- Testing
- Recovery Enhancement Program
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Cancer Survivor, Depression
Helping African American Prostate Cancer Survivors and Their Partners Cope With Challenges After Surgery for Prostate Cancer
RATIONALE: Telephone counseling after radical prostatectomy may help African American prostate cancer survivors and their intimate partners cope with the problems and challenges of surgery, and may reduce distress and improve…
- Conditions
- Cancer Survivor, Depression, Gastrointestinal Complications, Male Erectile Disorder
- Trial name
- NCT00869739
- Testing
- telephone-based intervention, educational intervention, partner-assisted coping skills training
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Stroke
R01.Aim 2.Study 1: IsoReach
To determine the effects of 3D isometric movement training in healthy participants and impaired participants due to a stroke.
- Trial name
- NCT06656754
- Testing
- Isometric Reaching
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Obese Adolescents, Bariatric Surgery
Study Effects of Preoperative Modafinil on Recovery Profile of Morbidly Obese Patients Scheduled for Bariatric Surgery if it Can Enhance Recovery From Anesthesia
study Effects of Preoperative Modafinil on Recovery Profile of Morbidly Obese Patients Scheduled for Bariatric Surgery if it Can Enhance Recovery From Anesthesia and provide improvement in recovery
- Trial name
- modafinil (NCT07128719)
- Testing
- Modafinil
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Stroke
Aha BOOST Arm-hand BOOST Therapy to Enhance Recovery After Stroke: Clinical, Health Economic and Process Evaluation
The overall aim of this study is to establish the clinical- and cost-effectiveness of the arm-hand BOOST therapy when delivered on top of the usual care program in the sub-acute phase post stroke and to perform a process…
- Trial name
- AHA-BOOST (NCT06517251)
- Testing
- Arm-hand BOOST, Lower limb BOOST
- Where
- 2 sites in Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Chronic Stroke Patient, Motor Impairment
Multifocal Theta-Burst Stimulation to Enhance Upper Limb Motor Recovery After Stroke (INSPIRE)
Stroke is one of the leading causes of long-term disability worldwide. Many individuals who survive a stroke continue to experience weakness and reduced control of one arm, even months or years after the event.
- Conditions
- Chronic Stroke Patient, Motor Impairment, Neurorehabilitation, Theta Burst Stimulation
- Trial name
- INSPIRE (NCT07439367)
- Testing
- Active iTBS, Tablet-based upper limb training
- Where
- Switzerland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- School of Health Sciences Geneva
Nursing Education
Effect of ERAS Protocol Education on Nursing Students' Knowledge and Attitudes
Enhanced Recovery After Surgery (ERAS) is an evidence-based approach increasingly used in surgical care to improve recovery and reduce postoperative complications.
- Trial name
- (ERAS-NS) (NCT07588464)
- Testing
- ERAS Protocol Education
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul Arel University
Colorectal Cancer, Liver Metastasis
Surgical Recovery After Left Lateral Hepatic Sectionectomy: Laparoscopic Versus Open Surgery.
The ORANGE II trial is a double blinded randomised controlled trial that will provide evidence on the merits of laparoscopic surgery in patients undergoing a left lateral hepatic sectionectomy in terms of time to functional…
- Conditions
- Colorectal Cancer, Liver Metastasis, Liver Disease
- Trial name
- ORANGE II (NCT00874224)
- Testing
- laparoscopic left lateral hepatic sectionectomy, open left lateral hepatic sectionectomy
- Where
- Netherlands
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Pain, Postoperative
Enhanced Recovery With Liposomal Bupivacaine in Orthognathic Surgery
The proposed study design is a prospective, clinical trial comparing control group patients (CG; ncg = 30) that will undergo conventional perioperative management without an ERAS protocol and standard bupivacaine intraoperative…
- Trial name
- NCT03844451
- Testing
- Liposomal Bupivacaine, Bupivacaine and Epinephrine
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Surgery, Enhanced Recovery
The Step Home Trial: Utilising Physical Activity Data in the Acute Post-operative Setting
This is an observational study, which aims to assess how physical activity levels following surgical procedures correlate with patient recovery and length of hospital stay, as well as the utility of this physical activity data to…
- Conditions
- Surgery, Enhanced Recovery, Technology
- Trial name
- NCT02583711
- Testing
- Activity sensor (3 axis accelerometer)
- Where
- United Kingdom
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Imperial College London