Clinical trials: Enhanced Recovery Pathway
Obesity
Enhanced Recovery After Surgery in Laparoscopic Sleeve Gastrectomy
While laparoscopic sleeve gastrectomy (LSG) has become the most commonly performed bariatric surgery procedure in the US and worldwide, it is associated with significant postoperative nausea and vomiting (PONV), which can lead to…
- Trial name
- NCT03520803
- Testing
- Enhanced recovery after surgery protocol
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Hartford Hospital
Ovary Cancer, Fallopian Tube Cancer
KORE-INNOVATION: a Prospective, Multi-site Clinical Trial to Implement and Analyse the Effects of an Innovative Perioperative Care Pathway to Reduce Complications for Patients with Ovarian Cancer
KORE-INNOVATION is a multi-center clinical study aiming to implement and analyze an innovative care pathway to reduce perioperative complications for patients undergoing surgical treatment for ovarian cancer.
- Conditions
- Ovary Cancer, Fallopian Tube Cancer, Peritoneum Cancer, Frailty
- Trial name
- KORE (NCT05256576)
- Testing
- Implementation of an innovative multi-modal peri-operative care pathway
- Where
- 2 sites in Germany
- Volunteers
- 465 people
- Sponsor
- Charite University, Berlin, Germany
Open Abdominal Surgery
Intrathecal Morphine for Quality of Recovery After Open Abdominal Surgery Within an Enhanced Recovery Pathway
Pain management after open abdominal surgery still faces severe challenges, with the incidence of moderate to severe pain after surgery as high as 50 - 90%.
- Trial name
- NCT07575321
- Testing
- Intrathecal Morphine, Intrathecal saline injection, TAPB
- Volunteers
- 756 people
- Sponsor
- Sun Yat-sen University
Prostate Cancer, Robot-Assisted Laparoscopic Radical Prostatectomy
Enhanced Recovery After Surgery (ERAS) Pathway in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy
Prostate cancer ranks second among all malignances in men and has become a significant threat to men's health. Robot-assisted laparoscopic radical prostatectomy (RARP) has become a standard treatment for prostate cancer.
- Conditions
- Prostate Cancer, Robot-Assisted Laparoscopic Radical Prostatectomy, Enhanced Recovery After Surgery (ERAS) Protocol, Prehabilitation
- Trial name
- NCT05576766
- Testing
- Routine care, ERAS management pathway
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Peking University First Hospital
Postoperative Pain
Sufentanil Sublingual Tablet System for Postoperative Pain Management After Total Knee Arthroplasty
The aim of this study is to assess the effectiveness of Sublingual Sufentanil Tablets System (SSTS, Zalviso ®) to control postoperative pain after total knee arthroplasty in the context of early rehabilitation program.
- Trial name
- NCT04448457
- Testing
- Sufentanil Sublingual Tablet, Oxycodone oral tablet and oxycodone extended-release oral tablet
- Where
- Belgium
- Volunteers
- 72 people
- Sponsor
- Centre Hospitalier Universitaire de Tivoli
Peritoneal Cancer
Four Quadrants Transverse Abdominus Plane (4Q-TAP) Block With Plain and Liposomal Bupivacaine vs. Thoracic Epidermal Analgesia (TEA) in Patients Undergoing Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC) on an Enhanced Recovery Pathway
The goal of this clinical research study is to compare the effects of 4 quadrant TAP block (4Q-TAP block) with the standard-of-care thoracic epidural analgesia (TEA) in patients recovering from cytoreductive surgery with…
- Trial name
- NCT03359811
- Testing
- Local Anesthetic Solution, Bupivacaine HCl, Liposomal Bupivacaine
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- M.D. Anderson Cancer Center
ERAS, Cancer
Enhanced Recovery After Surgery(ERAS) Following Gynaecological Oncology Surgery in a Tertiary Level Hospital
Enhanced recovery after surgery (ERAS) protocols are multimodal perioperative care pathways designed to achieve early recovery after surgical procedures by maintaining preoperative organ function and reducing the profound stress…
- Trial name
- NCT07087366
- Testing
- ERAS protocol
- Where
- Bangladesh
- Volunteers
- 130 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Adenocarcinoma of Stomach, Critical Pathways
POWER AUDIT, Postoperative Outcomes Within an Enhanced Recovery After Surgery Protocol After Gastric Surgery (POWER 4 + 3)
The main objective of this study is to analyze the impact on three years survival of an enhanced recovery program (PRI) after radical surgert for adenocarcinoma gastric cancer.
- Conditions
- Adenocarcinoma of Stomach, Critical Pathways, Enhanced Recovery After Surgery (ERAS) Protocol, Retrospective Studies
- Trial name
- POWER 4 + 3 (NCT06790238)
- Testing
- gastric surgery and ERAS protocol
- Where
- 22 sites in Spain
- Volunteers
- 350 people
- Sponsor
- Grupo Español de Rehabilitación Multimodal
Intraoperative Complication, Malignant Female Reproductive System Neoplasm
Epidural Anesthesia Within an Enhanced Recovery Pathway in Reducing Pain in Patients Undergoing Gynecologic Surgery
This randomized clinical trial studies epidural anesthesia within an enhanced recovery pathway (ERP) in reducing pain in patients undergoing gynecologic surgery.
- Conditions
- Intraoperative Complication, Malignant Female Reproductive System Neoplasm, Pain
- Trial name
- NCT02423876
- Testing
- Epidural analgesia, Intraoperative Complication Management and Prevention, Pain Therapy
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Wisconsin, Madison
Nurse's Role
Effect of Nurse Guided Enhanced Recovery Clinical Pathway on Respiratory Infection
Objectives: Evaluate the effect of a nurse guided enhanced recovery pathway on postoperative respiratory tract infection in Hepatico-Pancreatic -Biliary surgery [ pre-operative patient counselling for postoperative respiratory…
- Trial name
- NCT06812182
- Testing
- nurse guided clinical pathway
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Cesarean Section
Cesarean Section Via Enhanced Recovery
Enhanced Recovery After Surgery (ERAS) protocols have been proven to be very successful in specific patient populations. An example is with ERAS for colorectal surgery.
- Trial name
- NCT03552822
- Testing
- ERAS Protocol Implementation
- Where
- United States
- Volunteers
- 541 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Esophageal Cancer Surgery
Prehabilitation in Esophageal Surgery (PRESS)
Despite important clinical improvements, esophageal cancer surgery is still associated to a high rate of postoperative complications.
- Trial name
- PRESS (NCT03798951)
- Testing
- Prehabilitation
- Where
- Italy
- Volunteers
- 21 people
- Sponsor
- Università Vita-Salute San Raffaele
Cholecystitis, Acute, Cholecystectomy, Laparoscopic
Implementation of RICA (ERAS) Guidelines in Grade II Acute Cholecystitis Undergoing Early Laparoscopic Cholecystectomy
Background Acute cholecystitis (sudden gallbladder inflammation, usually due to gallstones) is a highly frequent surgical emergency.
- Conditions
- Cholecystitis, Acute, Cholecystectomy, Laparoscopic, Enhanced Recovery After Surgery
- Trial name
- COLERICA II (NCT07695922)
- Testing
- RICA Perioperative Care Pathway
- Where
- Spain
- Volunteers
- 146 people
- Sponsor
- Hospital d'Igualada
Mastectomy, Breast Cancer Female
Efficacy of Enhanced Recovery After Surgery Pathway for Total Mastectomy
Retrospective analysis of pre and post-Enhanced Recovery after Surgery for Total mastectomy pathway implementation.
- Trial name
- ERAS_Breast (NCT03181139)
- Testing
- ERAS pathway for Total Mastectomy
- Volunteers
- 386 people
- Sponsor
- Monica Harbell
Morbid Obesity
Comparison of Enhanced Recovery After Surgery (ERAS) Pathway With Conventional Pathway After Laparoscopic Sleeve Gastrectomy
The aim of this study is to compare two postoperative recovery pathways namely, enhanced recovery after surgery (ERAS) pathway and conventional recovery pathway after laparoscopic sleeve gastrectomy with respect to outcomes…
- Trial name
- BARI-ERAS (NCT03191318)
- Testing
- ERAS pathway, Standard pathway
- Where
- India
- Volunteers
- 60 people
- Sponsor
- GEM Hospital & Research Center
Malignant Neoplasms of Female Genital Organs, Gynecologic Cancer
Wound Infiltration With Liposomal Bupivacaine vs. Standard Wound Infiltration With Bupivacaine in Patient's Undergoing Open Gynecologic Surgery on an Enhanced Recovery Pathway
Bupivacaine is a drug that is traditionally given as an injection to numb surgical sites. Liposomes are molecules that are similar to fats.
- Trial name
- NCT02740114
- Testing
- Bupivacaine, Liposomal Bupivacaine, Oxycodone
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- M.D. Anderson Cancer Center
Osteoarthritis, Knee, Osteoarthritis, Hip
Study of Hip and Knee Arthroplasty in South Africa
This multi-site, observational, prospective study aims to investigate current practice and associated outcomes for patients scheduled for elective unilateral total hip or knee arthroplasty in South Africa.This information will…
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Arthritis, Rheumatoid, Arthritis Knee
- Trial name
- NCT03540667
- Where
- 9 sites in South Africa
- Volunteers
- 206 people
- Sponsor
- University of Cape Town
Pain, Postoperative
Intraoperative Liposomal Bupivacaine vs. Bupivacaine for Total Hip Replacement Pain Management
The purpose of this study is to compare two medications currently injected intra-operatively to help decrease pain after surgery in patients undergoing a primary total hip replacement (THR).
- Trial name
- NCT03001453
- Testing
- Liposomal Bupivacaine, 0.25% Bupivacaine with epinephrine, Saline
- Where
- 2 sites in United States
- Volunteers
- 107 people
- Sponsor
- American Hip Institute
Implementation of Enhanced Recovery Pathway
PERFECTED WP2: Implementing Optimised Hospital Care
This study is part of the 5-year long (2013-18) PERFECTED (Peri-operative Enhanced Recovery hip-fracture Care of paTiEnts with Dementia) National Institute for Health Research (NIHR) funded research programme.
- Trial name
- PERFECTED (NCT03269487)
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
ERAS, Obesity
ERAS After Bariatric Surgery in Morbidly Obese
Recently, the number of bariatric surgery is increasing but ERAS (Enhanced Recovery After Surgery) protocol for bariatric surgery needs revision with evidence.
- Trial name
- NCT04891822
- Testing
- ERAS protocol
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Seoul National University Bundang Hospital