Clinical trials: Entropy
Anesthesia, General
Comparison of the Bispectral Index and the Entropy of the Electroencephalogram During Total Intravenous Anesthesia
To compare Bispectral index and entropy during maintenance of anesthesia
- Trial name
- NCT00391963
- Testing
- Bispectral index, Entropy
- Where
- 2 sites in France
- Volunteers
- 84 people
- Sponsor
- Hopital Foch
Persistent Atrial Fibrillation
CARTO-Finder Guided Ablation Versus Multiscale Entropy Guided Ablation in Persistent Atrial Fibrillation
This is a randomized control trial to compare the efficacy and safety of CARTO-Finder-guided ablation plus pulmonary vein isolation versus multiscale entropy (MSE)-guided pulmonary vein isolation in patients with persistent…
- Trial name
- NCT05454111
- Testing
- Multiscale entropy-guided ablation plus PVI, CARTO-Finder-guided ablation plus PVI
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai Chest Hospital
All Conditions Requiring Non-cardiac Surgery
Impact of Training on the Use of Software and Digital Monitoring Tools During General Anesthesia for Intermediate/Major-risk Surgery on Morbidity and Mortality at 28 Days
Tools such as surgical plethysmographic index, state entropy, train-of-four monitors exist to optimize the conduct of general anesthesia in intermediate and major risk surgery as defined by the 2022 European Society of Cardiology…
- Trial name
- AoA QUALITY (NCT06111248)
- Testing
- Training
- Where
- France
- Volunteers
- 1,028 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Obstructive Sleep Apnoea (OSA)
Entropy-based Physiological Signal Analysis in Patients With Obstructive Sleep Apnoea
This observational study is being undertaken as a part of a Master of Research (MRes) in Clinical Research programme. Its goal is to learn about how continuous positive airway pressure (CPAP) therapy changes the complexity of…
- Trial name
- EPPOSA (NCT07406620)
- Testing
- Continuous Positive Airway Pressure Therapy
- Where
- 2 sites in United Kingdom
- Volunteers
- 56 people
- Sponsor
- King's College London
Anaesthesia
Sugammadex and Brain Waves
According to our experience, electroencephalogram-based indices of anaesthetic state show elevated numbers after administration of sugammadex (new reversal of neuromuscular blockade).
- Trial name
- NCT01142648
- Testing
- Sugammadex, Neostigmine and glycopyrrolate
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Tampere University Hospital
Endoscopic Sinus Surgery
PRD-guided Analgesia During FESS for Intraoperative Blood Loss
The aim of this randomized trial is to assess the utility of Pupillary Dilatation Reflex (PRD) for monitoring pain perception intraoperatively and its influence on intraoperative blood loss, quality of surgical field using…
- Trial name
- FESSPRD (NCT03417206)
- Testing
- Remifentanil, pupillary dilatation reflex
- Volunteers
- 120 people
- Sponsor
- Medical University of Silesia
Anaesthesia
Dexmedetomidine-propofol-remifentanil Anaesthesia and Reactivity to Noxious Stimuli
Dexmedetomidine acts at central nervous system (specifically: at locus caeruleus), providing sedative and analgesic effects. It is widely used in intensive care.
- Trial name
- NCT01076790
- Testing
- Dexmedetomidine, Saline
- Where
- Finland
- Volunteers
- 44 people
- Sponsor
- Arvi Yli-Hankala
Anesthesia, General
Target-controlled Infusion of Propofol and Remifentanil During General Anaesthesia Guided by Entropy
This study compares the manual administration of propofol and remifentanil and their delivery using a combined closed-loop anesthesia system, entropy of the EEG being the controller.
- Trial name
- NCT00391885
- Testing
- Closed-loop anesthesia system
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- Hopital Foch
Conscious Sedation, Deep Sedation
Effects of Two Different Sedation Regimes on Auditory Evoked Potentials and Electroencephalogram (EEG)
Sedation may be necessary in intensive care to facilitate diverse therapeutic interventions, but the use of sedative drugs may increase the risk of delirium and long-term cognitive impairment.
- Conditions
- Conscious Sedation, Deep Sedation, Critical Care
- Trial name
- NCT00641563
- Testing
- Dexmedetomidine, Midazolam, Remifentanil
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
General Anesthesia
Comparative Analysis of Phase Lag Entropy (PLE) and Bispectral Index (BIS) as an Anesthetic Depth Indicator
The aim of this comparative analysis is to evaluate the reliability of PLE value as an anesthetic depth indicator
- Trial name
- NCT03424720
- Testing
- PLE and BIS
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Hallym University Medical Center
Bronchial Asthma, Bronchiectasis
The Use of Entropy to Assess Sleep Disordered Breathing in Chronic Respiratory Disease
Research is being conducted into chronic respiratory diseases, including chronic obstructive pulmonary disease (COPD), asthma, interstitial lung disease, and bronchiectasis.
- Conditions
- Bronchial Asthma, Bronchiectasis, ILD, COPD
- Trial name
- NCT07060079
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University College, London
Chronic Kidney Disease on Hemodialysis
Quantification of Autonomic Nervous Activity During Hemodialysis
This study assesses autonomic nervous system function by power spectral analysis of RR interval dynamics in ultrafiltration subjects without blood pressure variation.
- Trial name
- NCT02754986
- Testing
- Analysis of the holter electrocardiogram
- Where
- Japan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Hyogo
Anesthesia
Hypnotic and Anti-nociceptive Components of Magnesium
The aim of our study is to evaluate the effect of magnesium on the hypnotic effect of propofol.
- Trial name
- NCT05005494
- Testing
- Magnesium sulfate IV
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Liege
Trauma, General Anaesthetic Drug Overdose
Modulation of General Anesthesia Using Entropy and Surgical Pleth Index
The critically ill polytrauma patient is one of the most complex cases with regard to the optimization of the intensive care, anesthesia, as well as postoperative management.
- Trial name
- ESPTR (NCT03095430)
- Testing
- Monitoring
- Volunteers
- 72 people
- Sponsor
- Romanian Society of Anesthesia and Intensive Care
Anesthesia, Child
Performance Evaluation of the Depth of Anesthesia Monitors in Pediatric Surgery
The purpose of this study is to determine how Bispectral index (BIS) and Entropy EEG monitors agree between themselves and with end-tidal concentration of sevoflurane (ETsevo) in relationship with the age in the pediatric surgery…
- Trial name
- NCT02240368
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Foggia
Delirium - Postoperative
Correlation Between Perioperative EEG Variability and Postoperative Delirium Incidence.
This clinical study aims to investigate whether multiscale entropy analysis of electroencephalogram data can distinguish between ordinary elderly surgical patients and elderly patients with postoperative delirium.This study may…
- Trial name
- NCT07323940
- Testing
- Collect preoperative and intraoperative electroencephalogram data
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Xin Chen
Anesthesia Awareness
Entropy and Surgical Pleth Index Guided Closed Loop Target Controlled Infusion Total Intravenous Anesthesia With Propofol
Closed-loop infusion system for target controlled infusion of propofol by using TCI pump designed by BD Technology. (Germany) guided with entropy and surgical pleth index (GE) will not only prevent awareness from Anesthesia but…
- Trial name
- Closedloop TCI (NCT03773588)
- Testing
- Closed-Loop propofol Target controlled infusion by Entropy and SPI, Open-loop propofol target controlled infusion
- Where
- India
- Volunteers
- 40 people
- Sponsor
- KVG Medical College and Hospital
Entropy Device and How Will Muscle Relaxants Affect it
Effect of Atracurium and Rocuronium on the State and Response Entropy During Isoflurane Anesthesia
Many studies have explored the effects of inhalation anesthetics, intravenous anesthetics, and muscle relaxants on spectral entropy, but most did not monitor the degree of neuromuscular block.
- Trial name
- NCT05097508
- Testing
- Atracurium Besylate, Rocuronium Bromide, Entropy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Surgery Requiring Spinal Anesthesia
Validation of Phase Lag Entropy(PLE) as an Indicator of Depth of Sedation in Patients Undergoing Spinal Anesthesia
For verifying the phase lag entropy as the tool for measurement of level of consciousness, the investigators compared phase lag entropy to bispectral index.
- Trial name
- NCT03319004
- Testing
- apply phase lag entropy sensor
- Where
- South Korea
- Volunteers
- 27 people
- Sponsor
- Gangnam Severance Hospital
Colonic Diseases, Functional
Adequacy of Anaesthesia for Colonoscopic Procedures
The aim of this randomized prospective trial is to assess the utility of Adequacy of Anaesthesia technique (Response Entropy and Surgical Pleth Index) for monitoring pain perception intraoperatively and its influence on…
- Trial name
- AoAColon (NCT03922815)
- Testing
- rescue fentanyl, rescue propofol
- Where
- Poland
- Volunteers
- 158 people
- Sponsor
- Medical University of Silesia