Clinical trials: Environmental Conditions
Spina Bifida, Anencephaly
Study of Genetic Risk Factors for Spina Bifida and Anencephaly
The purpose of this study is to describe the genetic contribution to the neural tube defects spina bifida (SB) and anencephaly (A), which includes identifying patients, defining the roles of certain genes, and studying…
- Trial name
- SBRR (NCT00031122)
- Testing
- No Intervention
- Where
- 2 sites in United States
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Salmonella Infections, Infection of Bloodstream
Reservoir of Invasive Salmonellosis in Children, DRC
Bloodstream infections caused by non-typhoid Salmonella (NTS) are a major killing disease in Sub-Saharan Africa. Despite the high case fatality rate, the main reservoir -human, zoonotic or environmental- for invasive NTS rests…
- Trial name
- NCT03073707
- Testing
- Sample collection
- Where
- Democratic Republic of the Congo
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Physical Activity, Obesity
Evaluating the Effectiveness of the Dissemination of Action Schools! BC
Childhood obesity is a major public health threat. Physical activity and healthy eating contribute to the maintenance of healthy weights.
- Conditions
- Physical Activity, Obesity, Physical Fitness
- Trial name
- AS!BC (NCT01412203)
- Testing
- Action Schools! BC
- Where
- 2 sites in Canada
- Volunteers
- 1,529 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Glaucoma
Adult Providing Access to the Visual Environment (PAVE) - Glaucoma Pilot
We wish to evaluate a potential training program for patients with glaucoma, to become more efficient users of prescribed low vision devices for distance and near vision tasks.
- Trial name
- PAVE (NCT00338208)
- Testing
- Training in the Use of Low Vision Devices
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Overweight
Promoting Water Consumption for Prevention of Overweight in School Children in a Controlled Intervention Trial
A major goal in public health is to find effective, feasible and simple programs for overweight prevention among children. This controlled intervention study evaluates a simple environmental and behavioral modification for its…
- Trial name
- trinkfit (NCT00554294)
- Testing
- environmental and behavioral change
- Volunteers
- 2,950 people, healthy volunteers welcome
- Sponsor
- Research Institute of Child Nutrition, Dortmund
Obesity
Healthy Kids & Families: Overcoming Social, Environmental and Family Barriers to Childhood Obesity Prevention
The study will test the impact of a community health worker (CHW)-delivered intervention aimed at helping families overcome barriers to childhood obesity prevention. Barriers include social, environmental, and family issues.
- Trial name
- NCT03028233
- Testing
- Healthy Lifestyle, Positive Parenting
- Where
- United States
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Obesity
Environmental Strategies & Behavior Change to Reduce Overeating in Obese Children
There is a need for effective weight control methods for obese children. Environmental strategies such as reducing the size of dishware and serving utensils, storing food out of view and reducing food consumption while watching…
- Trial name
- NCT01221220
- Testing
- Standard Packard Pediatric Weight Control Program, Standard Packard Pediatric Weight Control Program plus Home-based advising on environmental changes
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Stanford University
Chronic Obstructive Pulmonary Disease, Healthy
Biosensor and Environmental Sensor Development Within the REMEDIA Project
The aim of this proof-of-concept study is to obtain data that will contribute to the development of sensor devices (biosensor and environmental sensor) for patients with lung diseases (e.g. COPD).
- Trial name
- NCT06035276
- Testing
- Exposure to clean air, Exposure to urban air
- Where
- Germany
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Anorexia Nervosa in Remission, Eating Disorder
Eating Concerns and Compulsivity
This study uses a computational task to examine differences in adaptive learning to both rewards and punishments between three groups: those who have recovered from anorexia nervosa, those who score highly on the EAT-26 (Eating…
- Trial name
- NCT03450291
- Testing
- Volatility task
- Where
- United Kingdom
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health in Tavua, Fiji
Ambient air temperatures in Fiji are increasing due to climate change. Solutions are needed to build heat resilience in communities and adapt.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- NCT07592117
- Testing
- Cool roof
- Where
- Fiji
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health in Colima, Mexico
Ambient air temperatures in Mexico have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate change.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06834893)
- Testing
- Cool roof
- Where
- Mexico
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Hearing Loss, Functional
The Effectiveness of Over the Counter Hearing Products for Middle-Aged Adults
The investigators will examine the effectiveness of selected over-the-counter personal sound amplifiers in addressing functional hearing problems in middle-aged listeners with mild hearing loss.
- Trial name
- NCT03511417
- Testing
- over-the-counter hearing device
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Exposure to Environmental Pollution, Non-occupational
Epigenetic Effect Modifications With Ozone Exposure on Healthy Volunteers
The purpose of this protocol is to assess whether epigenetic factors in healthy individuals make a person more or less responsive to lung inflammation following ozone exposures.
- Trial name
- Geminoz (NCT02469428)
- Testing
- Clean air, Ozone
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Environmental Protection Agency (EPA)
HIV-1 Seropositive, Inflammation
Study of the Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage
Background: Research has shown that certain proteins in cells may be linked to higher risks of developing inflammations, tumors, and other medical problems.
- Conditions
- HIV-1 Seropositive, Inflammation, Cancer, Cardiomyopathy
- Trial name
- NCT01143519
- Where
- United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Atrial Fibrillation
A Study to Investigate if Early Atrial Fibrillation (AF) Diagnosis Reduces Risk of Events Like Stroke in the Real-World
The primary objectives of this study are to identify and diagnose Atrial Fibrillation (AF), evaluate improvement in cardiovascular (CV) outcomes, improve direct oral anti-coagulant (DOAC) adherence and persistence, and better…
- Trial name
- NCT04276441
- Testing
- Heart healthy Engagement Program with the Apple Watch Series 5 or later, Anti-Coagulation Adherence Module with the Apple Watch Series 5 or later
- Where
- United States
- Volunteers
- 34,244 people, healthy volunteers welcome
- Sponsor
- Janssen Scientific Affairs, LLC
Childhood Obesity
International Study of Childhood Obesity, Lifestyle and the Environment
The primary aim of the International Study of Childhood Obesity, Lifestyle and the Environment (ISCOLE) is to determine the relationship between lifestyle characteristics and obesity in a large multi-national study of 10 year-old…
- Trial name
- ISCOLE (NCT01722500)
- Where
- 12 sites in United States, Australia and 10 more
- Volunteers
- 7,806 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Obesity
Study of Parenting Intervention to Prevent Child Obesity
This purpose of this project is to determine whether this 8-month parenting for healthy weight intervention is able to help parents improve their parenting skills and make positive changes in the nutrition and physical activity…
- Trial name
- NCT00998348
- Testing
- Parenting Program
- Where
- United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Obesity
Vivamos Activos Fair Oaks Program for Weight Loss in Low Income Latinos
Physician-based primary care has thus far failed to address the obesity epidemic. In this randomized clinical trial of 200 obese patients with heart disease risk factors, the investigators will evaluate the impact of nurse and…
- Trial name
- VAFO (NCT01242683)
- Testing
- Vivamos Activos Fair Oaks Program
- Where
- 4 sites in United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Stanford University
Overweight, Obesity
Challenge! Adolescent Obesity Prevention
The prevalence of overweight among adolescents (BMI-for-age %tile over the 95th percentile) has more than tripled over the past 3 decades in the US.
- Trial name
- Challenge (NCT03103269)
- Testing
- Challenge! Small Group Intervention, Challenge! Environmental Intervention
- Where
- United States
- Volunteers
- 789 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Genetic Predisposition to Disease, Environment
Correlation Between Psychological Resilience and Genetic, Inflammatory Indicators
The goal of this observational study is to evaluate and analyze the influencing factors of the adaptive ability of young people, explore the impact of the interaction of environment and gene on the psychological adaptive ability…
- Conditions
- Genetic Predisposition to Disease, Environment, Adaptation, Psychological, Inflammation
- Trial name
- NCT06193005
- Testing
- no intervention
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Qianfoshan Hospital