Clinical trials: Epidural/Anesthesia
C23.550.767.700, C23.550.470
The Effect of Preoperative NLR Level on Epidural Analgesia Application in Thoracotomy
The aim of this study is to investigate the relationship of preoperative Neutrophil/Lymphocyte Ratio (NLR) with postoperative pain and the effect of preoperative NLR level on timing of epidural analgesia in thoracotomy.
- Trial name
- NCT05209958
- Testing
- Neutrophil Lynphosite ratio
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Karadeniz Technical University
Depression, Postpartum, Pregnancy
Labor Pain and Postpartum Behavioral Health Outcomes Study
In this pilot prospective longitudinal observational study, women who are pregnant and who will be experiencing childbirth for the first time will be recruited at the third trimester and observed longitudinally for psychiatric…
- Conditions
- Depression, Postpartum, Pregnancy, Child Development, Pain
- Trial name
- LPPD (NCT02692404)
- Where
- 2 sites in United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Pregnancy
Does Ultrasound Help Junior Anesthesia Residents With Placement of Labor Analgesia in Pregnant Patients
The investigators believe that ultrasound guided CSE technique will help junior resident rotating for the first time on the labor and delivery floor to place more accurately the epidural needle in the midline position as compared…
- Trial name
- NCT02747238
- Testing
- Ultrasound, No ultrasound, Epidural infusion
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Labor Pain
Programmed Intermittent Epidural Bolus Time Interval and Injection Volume
Studies suggest that administration of maintenance epidural solutions as programmed or automated intermittent boluses, rather than continuous infusions, result in lower bupivacaine consumption, decreased need for manual boluses…
- Trial name
- NCT00417027
- Testing
- Programmed Intermittent Epidural Bolus (PIEB)
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Epidural Anesthesia, Percutaneous Nephrolithotomy (PCNL)
Predictors of Epidural Depth in Percutaneous Nephrolithotomy and Model Development
Accurate estimation of epidural depth is critical for safe epidural anesthesia during percutaneous nephrolithotomy (PCNL). Although various imaging modalities can predict epidural depth, they increase healthcare burden and are…
- Trial name
- NCT07697053
- Where
- China
- Volunteers
- 3,278 people
- Sponsor
- Tongji Hospital
Coronary Artery Disease
Epidural Anesthesia and Postoperative Analgesia With Ropivacaine and Fentanyl
The aim of the present study was to assess the efficacy of thoracic epidural anesthesia followed by postoperative epidural infusion and patient-controlled epidural analgesia with ropivacaine/fentanyl in off-pump coronary artery…
- Trial name
- NCT01384175
- Testing
- intravenous analgesia, epidural infusion, patient-controlled epidural analgesia
- Where
- Russia
- Volunteers
- 93 people
- Sponsor
- Northern State Medical University
Total Knee Arthroplasty
Analgesia After Total Knee Replacement Surgery
Postoperative pain after total knee replacement surgery is difficult to treat. Mobilisation and hospital discharge might be delayed.
- Trial name
- NCT01489631
- Testing
- naropin, marcaine, sufentanil
- Where
- Netherlands
- Volunteers
- 81 people
- Sponsor
- St. Antonius Hospital
Labor, Epidural Analgesia
Pulse Pressure Variability With Position Before EPIdural Analgesia
Fetal heart rate abnormalities are common. Miller et al. have demonstrated that new onset fetal heart rate abnormalities after initial labor epidural dosing occur more frequently in women with a low admission pulse pressure than…
- Trial name
- PP-PERI (NCT03126136)
- Testing
- Nicom (TM)
- Where
- 4 sites in France
- Volunteers
- 1 people
- Sponsor
- Hopital Foch
Chronic Postoperative Pain, Open Heart Surgery
Comparison of IV Analgesia, Thoracic Epidural Analgesia, and ESP Block for Chronic Pain After Open Heart Surgery
This prospective observational study aims to compare three routinely used postoperative analgesia techniques in patients undergoing open heart surgery: intravenous analgesia, thoracic epidural analgesia (TEA), and bilateral…
- Conditions
- Chronic Postoperative Pain, Open Heart Surgery, Postoperative Analgesia, Analgesia
- Trial name
- TEA-ESPB-IV (NCT07257744)
- Testing
- Intravenous Analgesia, Thoracic Epidural Analgesia (TEA), Erector Spinae Plane Block (ESPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Karadeniz Technical University
Postpartum Urinary Retention
Effect of Voiding Position (Standing in the Shower vs. Sitting) on Post- Void Residual Urine Volume (PVR) After Removal of Urinary Catheter in Women Following Vaginal Delivery With Epidural Analgesia: A Double- Blind Randomized Controlled Trial
Postpartum urinary retention is a common complication after childbirth, with a higher risk for women who undergo vaginal delivery with epidural analgesia.
- Trial name
- NCT07893119
- Testing
- Standing in the shower, Sitting on the toilet
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assuta Ashdod Hospital
Lung Cancer, Pain, Postoperative
Optimal Postoperative Pain Management After Lung Surgery (OPtriAL)
Adequate pain control after video-assisted thoracoscopic surgery (VATS) for lung resection is important to improve postoperative mobilisation, recovery, and to prevent pulmonary complications.
- Conditions
- Lung Cancer, Pain, Postoperative, VATS, Locoregional Anaesthesia
- Trial name
- NCT05491239
- Testing
- Thoracic epidural analgesia, Continuous regional paravertebral block, Single shot intercostal nerve block
- Where
- Netherlands
- Volunteers
- 450 people
- Sponsor
- Maxima Medical Center
Pancreatic Cancer
Effects of Erector Spina Plan Block and Epidural Analgesia in Whipple Surgery
Pancreatic surgery is generally a high-risk and difficult to manage perioperatively. surgery. In pancreatic surgery, in addition to general anaesthesia, central blocks for analgesia and peripheral blocks are also preferred.
- Trial name
- NCT06254430
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Prostate Cancer
The Effect of Combined General/Epidural Anesthesia Versus General Anesthesia on Diaphragmatic Function
The aim of this study was to investigate whether robot assisted laparoscopic radical prostatectomy give rise to the impairment of diaphragmatic function postoperatively, and whether combined general/epidural anesthesia could…
- Trial name
- NCT01547416
- Testing
- epidural 250mL of 0.2% ropivacaine and 2 μg/mL of fentanyl, 5 mL/hr continuous infusion and 0.5 mL bolus dose, no epidural drug administered
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Yonsei University
Labor Pain, Breakthrough Pain
Development of Variable Volume Automated Mandatory Boluses for Patient-controlled Epidural Analgesia During Labour
A novel epidural delivery regimen was developed: Variable volume automated mandatory bolus (AMB) (VVAMB) will advance individualisation of labour epidural analgesia, by which a larger volume of bolus may contribute to better…
- Trial name
- VVAMB (NCT04011150)
- Testing
- Epidural infusion pump, Ropivacaine, Fentanyl
- Where
- Singapore
- Volunteers
- 197 people
- Sponsor
- KK Women's and Children's Hospital
Epidural Analgesia, Painless Labor
Dexmedetomidine or Fentanyl as Additives to Epidural Levobupivacaine in Painless Labor
Central neuraxial analgesia has been extensively used for labor analgesia and is currently the gold standard technique for pain control in obstetrics.
- Conditions
- Epidural Analgesia, Painless Labor, Dexmedetomidine, Fentanyl
- Trial name
- NCT04397406
- Testing
- levobupivacaine, Dexmedetomidine, Fentanyl
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Hepatectomy, Pain, Postoperative
Spinal Anesthesia For Enhanced Recovery After Liver Surgery
This project proposes to compare epidural versus spinal anesthesia in patients having liver resection surgery. The investigators hypothesize that spinal anesthesia will result in improved blood pressure control postoperatively…
- Conditions
- Hepatectomy, Pain, Postoperative, Liver Neoplasms
- Trial name
- SAFER-L (NCT03715517)
- Testing
- Continuous thoracic epidural analgesia, Spinal anesthesia with intrathecal morphine, Bupivacaine 0.75% in Dextrose Inj 8.25%
- Where
- Canada
- Volunteers
- 128 people
- Sponsor
- University of Manitoba
Ultrasound, Multilevel Erector Spinae Plane Block
Ultrasound-guided Multilevel Erectorspinae Plane Block Versus Thoracic Epidural Analgesia for Prevention of Post Mastectomy Pain Syndrome for Breast Cancer Patients
The aim of this study is to compare the analgesic efficacy of multilevel erector spinae plane block (ESPB) vs thoracic epidural in modified radical mastectomy (MRM) regarding duration of analgesia, postoperative opioid…
- Conditions
- Ultrasound, Multilevel Erector Spinae Plane Block, Thoracic Epidural Analgesia, Post Mastectomy
- Trial name
- NCT06884852
- Testing
- Erector spinae plane block (ESPB), Thoracic epidural block
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- National Cancer Institute, Egypt
Post Operative Analgesia, Opioid Consumption, Postoperative
Intravenous Acetaminophen to Reduce Post-operative Opioid Consumption
Acetaminophen (Tylenol) is a commonly used medication after surgery to control pain. Tablets for oral use and suppositories for rectal use are the most frequently employed forms of acetaminophen after surgery.
- Conditions
- Post Operative Analgesia, Opioid Consumption, Postoperative, Acetaminophen, Abdominal Surgeries
- Trial name
- ACETAPOP (NCT06923540)
- Testing
- IV Acetaminophen
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Thoracic Surgery, Epidural Anesthesia
The Effect of Regional Anesthesia Techniques on Brain Tissue Oxygenation in Thoracic Surgery
Today, it is preferred that the lung with pathology for thorax surgery is not under ventilation during operation in terms of reliability and ease of operation.
- Conditions
- Thoracic Surgery, Epidural Anesthesia, Cerebral Oxygen Saturation
- Trial name
- NCT04373174
- Testing
- Regional oximetry probe, Thoracic Epidural block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Anesthesia
Decreased Neuraxial Morphine After Cesarean Delivery
The purpose of this study is to compare 50mcg to 150mcg morphine in epidural for the goal of decreasing side effects of medication with lower dose in patients who receive a QL block
- Trial name
- NCT04279054
- Testing
- Morphine Sulfate 150 mcg, Morphine Sulfate 50mcg
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- University of Alabama at Birmingham