Clinical trials: Epidural/Anesthesia
Labor Pain
Prophylactic Ephedrine and Combined Spinal Epidurals for Labor
The combined spinal epidural (CSE) technique has become increasingly popular for labor pain because of its rapid onset and superior first stage analgesia.
- Trial name
- CEASE (NCT02062801)
- Testing
- Ephedrine
- Where
- United States
- Volunteers
- 710 people, healthy volunteers welcome
- Sponsor
- Sharp HealthCare
Perioperative Pain
Lumbar Epidural Analgesia With Bilateral Erector Spinae Block for Pain Management in Lumbar Spine Surgery
Surgical procedures on the spine and spinal cord are common and are performed for a wide variety of diseases. They range from minimally invasive, single-level decompression to highly complex, multi-stage extensive reconstruction.
- Trial name
- NCT04320212
- Testing
- lumber epidural analgesia, erector spinae analgesia
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Anesthesia, Analgesia
Conversion of Labor Analgesia for Intrapartum Cesarean Delivery: DPE v CSE v Epidural
As the dural puncture epidural (DPE) is increasing in popularity for labor analgesia, it is important to understand how it impacts outcomes in parturients.
- Trial name
- NCT05514431
- Testing
- Epidural, Dural Puncture Epidural (DPE) technique, Combined Spinal-Epidural (CSE) technique
- Where
- 2 sites in United States, Canada
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Epidural and Spinal Anesthesia for Cesarean Delivery
How Sweet is it? Measurement of Glucose in Epidural and Spinal Fluid
When a woman requires a cesarean section after labour, anesthesia is usually provided by a pre-existing epidural. Occasionally, the epidural does not work. The anesthesiologist then may give a "spinal anesthetic".
- Trial name
- NCT01391702
- Where
- 2 sites in Canada
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Epidural; Anesthesia, Headache, Analgesia
Comparison of Infiltration of 2% Lidocaine With and Without Needle as Analgesia in Epidural Needle Insertion
One way to reduce pain during epidural needle insertion is infiltration of lidocaine using a needle. However, infiltration of lidocaine using the needle alone is a painful process.
- Trial name
- NCT05326867
- Testing
- Infiltration of 2% Lidocaine with Needle, Infiltration of 2% Lidocaine without Needle
- Where
- Indonesia
- Volunteers
- 84 people
- Sponsor
- Universitas Indonesia
Prostatectomy, Transversus Abdominis Plane Blockade
Ultrasound-assisted Bilateral Transversus Abdominis Plane Block for Open Prostatectomy
The purpose of this study is to compare the quality of a transversus abdominis plane blockade with an intravenous pain therapy with opioids.
- Conditions
- Prostatectomy, Transversus Abdominis Plane Blockade, Pain
- Trial name
- TAPPro (NCT01625572)
- Testing
- Transversus abdominis plane blockade, Morphine-patient-controlled-analgesia-device
- Where
- Germany
- Volunteers
- 66 people
- Sponsor
- Charite University, Berlin, Germany
Anesthesia; Adverse Effect, Spinal and Epidural, Hypotension
Colloid Preload Versus Colloid Coload During Cesarean Deliveries
The investigators aimed to compare the methods colloid preloading and colloid coloading in terms of the incidence of maternal hypotension and impacts on neonatal outcomes.
- Trial name
- NCT02393196
- Testing
- hydroxyethyl starch (% 6 HES 130/0.4) (Voluven®), hydroxyethyl starch (%6 HES 130/0.4) (Voluven®)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sifa University
Epidural Anesthesia
Efficacy and Safety of Electric Stimulation-guided Epidural Anesthesia for Cesarean Section
Forty pregnant women (36 to 41 weeks gestation) will randomly allocate to two groups. Groups will be defined based on the method used to identify the epidural space for epidural anesthesia: the loss of resistance group (n=20) and…
- Trial name
- NCT03443466
- Testing
- Epidural electrical stimulation (EES), Loss of resistance (LOR)
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Korea University Guro Hospital
Epidural Anesthesia, Infection
The Effect of Combined General-epidural vs General Anaesthesia on Postoperative Gastrointestinal Surgery
Sixty neonates and infants will be enrolled and randomised into two groups of n=30 each . For their surgical procedures, one group general (GA) anaesthesia the second group will receive a combined general and epidural anaesthesia…
- Conditions
- Epidural Anesthesia, Infection, Infant, Newborn, Diseases
- Trial name
- NCT03056261
- Testing
- Combined general and epidural, General anaesthesia
- Volunteers
- 60 people
- Sponsor
- Bnai Zion Medical Center
Abdominal Surgeries
Epidural Block vs. Rectus Sheath Block on Postoperative Pulmonary Function
Pulmonary complications are among the most important postoperative complications after midline incisions, for which different analgesic modalities have been tried.
- Trial name
- NCT02660632
- Testing
- Thoracic epidural analgesia (TEA), Rectus sheath catheter block
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Cervical Radiculopathy
Ultrasound Guided Cervical Selective Nerve Root Block Versus Fluoroscopic Guided Cervical Transforaminal Epidural Block
This study retrospectively analyzed medical records and imaging records (ultrasound images, fluoroscopy-guided images) of US-CSNRB and FL-CTFEB procedures performed at the Yangsan Pusan National University Hospital Pain Clinic…
- Trial name
- NCT07447271
- Testing
- ultrasound guided cervical selective nerve root block, fluoroscopy-guided cervical transforaminal epidural block
- Where
- South Korea
- Volunteers
- 330 people
- Sponsor
- Pusan National University Yangsan Hospital
Epidural Analgesia, Obstetric
Effects of Epidural Lidocaine on the Pharmacokinetic and Pharmacodynamic Profiles of DepoDur® After Cesarean Delivery
To evaluate the levels of morphine in a patient's blood when morphine is given into the epidural space in the form of DepoDur® either alone or following a dose of lidocaine also given in the epidural space.
- Trial name
- NCT00804609
- Testing
- DepoDur following epidural lidocaine, DepoDur following spinal anesthetic
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Pain, Obesity
Effect of Body Mass Index on the Dose of Intrathecal Hyperbaric Bupivacaine for Elective Cesarean Section
Combined spinal - epidural (CSE) anesthesia is a well established technique used for elective Cesarean section. As its name suggests, it combines two anesthesia techniques - spinal and epidural.
- Trial name
- NCT00403663
- Testing
- bupivacaine 0.75% with fentanyl and morphine
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Pain
Tsui Test as a Predictor of Bupivacaine Consumption in Labour Epidurals
Low current electrical stimulation test, also called the Tsui test, has been used successfully to confirm the catheter location in the epidural space in various patient populations.
- Trial name
- NCT00792311
- Testing
- Tsui test
- Where
- Canada
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Lung Cancer
Comparison of Efficacy of Paravertebral and Epidural Analgesia After Videothoracoscopic Lung Lobectomy
Thoracic surgery correlates with significant pain in postoperative period. In order to alleviate the pain various combinations of pharmaceuticals and administration methods are employed.
- Trial name
- NCT02040662
- Testing
- Continuous Thoracic Epidural Block, Continuous Thoracic Paravertebral Block, Patient-Controlled Analgesia with Morphine
- Where
- Poland
- Volunteers
- 120 people
- Sponsor
- Pulmonary Hospital Zakopane
Combination of General Anesthesia to Spinal and Epidural Techniques
Combination of Spinal-Epidural With General Anesthesia in Patients Undergoing Mega-Liposuction Surgery
The combination of general anesthesia to spinal and epidural techniques (CSEGA) proved to have a synergistic effect, thus, the use of sub-anesthetic doses can provide satisfactory anesthetic and analgesic results.
- Trial name
- NCT05301127
- Testing
- spinal-epidural device
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caudal Epidural Anesthesia, Erector Spinae Plane Block
Comparison of Erector Spinae Plane Block and Caudal Block in Pediatric Patients Aged 1 to 8 Years Undergoing Lower Abdominal Surgery
In routine pediatric surgical practice, lower abdominal surgeries are commonly performed. Inadequate control of postoperative pain can hinder functional recovery and may lead to negative behavioral changes as well as parental…
- Conditions
- Caudal Epidural Anesthesia, Erector Spinae Plane Block, Pediatric
- Trial name
- NCT07426939
- Testing
- caudal block, Erector Spinae Plane Block
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Lung Cancer
Postoperative Pain After Single Port, Two Ports and Three Ports VATS Lobectomy
This single-center, prospective, randomized controlled trial was designed to assess and compare the postoperative pain after VATS lobectomy performed though one, two and three incisions.
- Trial name
- NCT03228056
- Testing
- pain intensity measured in VAS scale
- Where
- 2 sites in Poland
- Volunteers
- 90 people
- Sponsor
- Pulmonary Hospital Zakopane
Pain, Postoperative, Regional Anesthesia
Registry for Acute Pain Treatment
The German Network for acute pain management and Regional Anesthesia (NRA) is a multi-center, non-interventional registry and benchmark project, assessing and analysing clinical and patient-reported procedural and outcome data of…
- Trial name
- NCT02846610
- Where
- Germany
- Volunteers
- 224,744 people
- Sponsor
- University Hospital, Saarland
Intraoperative Complication, Malignant Female Reproductive System Neoplasm
Epidural Anesthesia Within an Enhanced Recovery Pathway in Reducing Pain in Patients Undergoing Gynecologic Surgery
This randomized clinical trial studies epidural anesthesia within an enhanced recovery pathway (ERP) in reducing pain in patients undergoing gynecologic surgery.
- Conditions
- Intraoperative Complication, Malignant Female Reproductive System Neoplasm, Pain
- Trial name
- NCT02423876
- Testing
- Epidural analgesia, Intraoperative Complication Management and Prevention, Pain Therapy
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Wisconsin, Madison