Clinical trials: Epidural/Anesthesia
Discomfort, Psychological Well Being
Patient Experiences of Intraoperative Discomfort During Cesarean Delivery Under Neuraxial Anesthesia
During a cesarean delivery done under spinal or epidural anesthesia, many patients notice sensations they weren't expecting things like pressure, pulling, tugging, or nausea even though the anesthesia blocks pain.
- Trial name
- ICAT (NCT07867106)
- Testing
- Interview
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Caesarean Delivery
Comparison of Different Methods of Pain Control After Cesarean Section for Patients on Buprenorphine or Methadone
More and more women are on buprenorphine or methadone during pregnancy for a history of opioid addiction. Currently, pain control after cesarean section for women already on these medications, if they need operative delivery, is…
- Trial name
- NCT02091297
- Testing
- TAP Block, Ropivacaine, Acetaminophen
- Where
- 3 sites in United States
- Sponsor
- Dartmouth-Hitchcock Medical Center
Labor Pain, Pregnancy
The Association Between Decreasing Labor Analgesia Epidural Infusion and Forceps Delivery
The objective of this study will be to compare epidural infusion management, specifically looking at infusion rate changes, in patients who receive forceps deliveries versus normal spontaneous vaginal deliveries.
- Trial name
- NCT00443560
- Testing
- Case controlled analysis of epidural labor analgesia patterns
- Where
- United States
- Volunteers
- 2,162 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pneumothorax, Primary Spontaneous, VATS
Optimal Postoperative Chest Tube and Pain Management in Patients Surgically Treated for Primary Spontaneous Pneumothorax (Pneumotrial)
Guidelines lack high quality evidence on optimal postoperative chest tube and pain management after surgery for primary spontaneous pneumothorax (PSP).
- Conditions
- Pneumothorax, Primary Spontaneous, VATS, Pain, Postoperative, Locoregional Anaesthesia
- Trial name
- NCT06053476
- Testing
- Thoracic epidural analgesia, Single-shot paravertebral block, Late chest tube removal
- Where
- Netherlands
- Volunteers
- 366 people
- Sponsor
- Maxima Medical Center
Hypotension
Pilot Study: Paravertebral Analgesia vs Epidural Analgesia After Thoracotomy
Paravertebral analgesia is non-inferior to epidural analgesia for pain control and superior to epidural analgesia in terms of the main complication of hypotension.
- Trial name
- ParaEpi (NCT01700491)
- Testing
- Epidural Catheter 0.2% ropivacaine, Paravertebral Catheter 0.4% ropivacaine
- Where
- 2 sites in Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Patient Who Needs Epidural Block
A Prospective Evaluation of Iodinated Contrast Flow Patterns in Caudal Epidurography With Intentional Lateral Caudal Approach
Caudal epidural block is useful not only for regional anesthesia of low abdominal, perineal area or lower extremities but for relieving acute or chronic pain of low back and lower extremities.
- Trial name
- NCT01136018
- Testing
- insertion needle via intentionally lateral direction.
- Where
- South Korea
- Volunteers
- 22 people
- Sponsor
- Yonsei University
Labor Analgesia
The Effect of Dural Puncture Epidural Block Technique on the Effectiveness and Safety of Labor Analgesia
Dural Puncture Epidural is a clinical improvement of Combined Spinal-Epidural and is widely used in Maternal.Dural Puncture Epidural Technique improves Labor Analgesia Quality And Safety By Increasing Drug Permeation.This study…
- Trial name
- DPE (NCT05990504)
- Testing
- ultrasound real-time guidance combined with Dural Puncture Epidural Labor Anagesia, ultrasound real-time guidance combined with Epidural Labor Anagesia
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Zongxun Lin
Labor, Obstetric, Epidural Analgesia, Obstetric
Integrated Intrapartum Supportive Care and Pushing Strategies in Women Receiving Low-Dose Epidural Analgesia
This prospective, three-arm, non-randomized quasi-experimental study aims to evaluate integrated intrapartum supportive care combined with different pushing strategies among women at 37-42 weeks of gestation who receive low-dose…
- Conditions
- Labor, Obstetric, Epidural Analgesia, Obstetric, Labor Duration
- Trial name
- NCT07663500
- Testing
- Integrated Care with Immediate Pushing, Integrated Care with Spontaneous Pushing Group, Standard Routine Care
- Where
- Taiwan
- Volunteers
- 159 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Epidural Anesthesia
Real-time Ultrasound Guided Labor Epidural Placement
Specific Aim: The purpose of this study is to determine if labor epidural placement using real-time (concurrent) ultrasound guided placement is superior to the conventional "standard" epidural technique without the use of…
- Trial name
- NCT00811304
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Liver Neoplasms, Hepatic Resection
Erector Spinae Plane Block Versus Thoracic Epidural Analgesia for Open Liver Resection
Background: Open liver resection is associated with severe postoperative pain. While thoracic epidural analgesia (TEA) is considered the gold standard for pain control, its clinical application is often limited by postoperative…
- Conditions
- Liver Neoplasms, Hepatic Resection, Liver Cancer
- Trial name
- NCT07642336
- Testing
- Continuous Erector Spinae Plane block, Thoracic Epidural Analgesia (TEA)
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Nguyen Toan Thang
Gastric Cancer
Comparative Study on the Effects of Epidural Dexmedetomidine on Heart Rate Variability During General Anesthesia in Patients Undergoing Gastrectomy
The use of epidural dexmedetomidine decreases the anaesthetic requirements and improved postoperative pain. Dexmedetomidine is a potent and highly selective a2-adrenoceptor agonist and has sympatholytic effect.
- Trial name
- NCT01857141
- Testing
- preemptive dexmedetomidine epidural bolus injection(1.5 mcg/kg), normal saline
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Yonsei University
Incidence, Unilateral
Is There a Relation Between Unilateral Epidural Block and Repeated Epidural Anesthesia?
epidural block is today the most common method of pain relief during labor. With increased use of epidural analgesia, many women are found in the second or third pregnancy and require repeated epidural analgesia.
- Conditions
- Incidence, Unilateral, Epidural Block
- Trial name
- NCT03806673
- Testing
- marcaine
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pregnancy, Breech Presentation
The Effect of Combined Spinal-Epidural Analgesia on the Success of External Cephalic Version (ECV) for Breech Position
We aim to answer the clinical question: Does combined spinal-epidural analgesia improve the success rate of external cephalic version? We hypothesize that neuraxial analgesia (spinal or epidural analgesia) during version for…
- Trial name
- Version (NCT00565383)
- Testing
- Combined spinal-epidural analgesia, Intravenous fentanyl (50mcg)
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Northwestern University
Labor Pain
Intermittent Automated Devices for Labor Analgesia in Emilia Romagna
The study aims to determine whether the use of automated intermittent devices for labor analgesia could prevent the increase of instrumental deliveries, with same analgesia.
- Trial name
- PA-RER (NCT02710877)
- Testing
- Programmed Intermittent bolus, Manual epidural bolus, Levobupivacaine
- Where
- 3 sites in Italy
- Volunteers
- 671 people
- Sponsor
- University of Modena and Reggio Emilia
Urinary Retention
Early Post-operative Removal of Urethral Catheter in Patients Undergoing Colorectal Surgery With Epidural Analgesia
Patients undergoing colon or rectal surgery will usually have a urinary catheter (silicone tube) placed in the bladder at the time of operating to monitor kidney function during surgery and in the post-surgery period.
- Trial name
- NCT01508767
- Testing
- Removal of urethral catheter
- Where
- Ireland
- Volunteers
- 41 people
- Sponsor
- University College Hospital Galway
Hypovolemia, Surgery
Volume Deficit Prior to Surgery
It is the purpose of the researchers to identify the variation in intravascular deficits which can have relevance in high risk patients for minor and medium sized surgery.
- Trial name
- NCT00380107
- Where
- Denmark
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Postoperative Pain
Clonidine and Morphine in Caudal Anesthesia
Hypothesis: The combined use of Clonidine and Morphine in caudal anesthesia provides better postoperative analgesia than either drug alone after urogenital pediatric surgery.
- Trial name
- NCT00672347
- Testing
- Clonidine, Morphine, Bupivacaine plus clonidine and morphine
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Federal University of Minas Gerais
Epidural/Anesthesia
Gravity Flow Technique to Validate Proper Location of Epidural Needle Tip on Obese Parturients
Pregnant women, with a Body Mass Index (BMI) greater than 30 kg/m2, who receive epidural analgesia/anesthesia for childbirth will have epidural catheter placement per our standard procedure, which includes using the gravity flow…
- Trial name
- NCT03437889
- Testing
- Cold Stimulus (Ice)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Asepsis, Analgesia, Epidural
Chlorhexidine Versus Povidone-Iodine for Prevention of Epidural Needle Contamination in the Parturient
Infection after epidural catheter placement is fortunately rare. When it does happen, the affected person can become seriously ill.
- Conditions
- Asepsis, Analgesia, Epidural, Anesthesia, Epidural
- Trial name
- NCT00223002
- Testing
- Chlorhexidine
- Where
- Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Pain
Influence of Epidural Analgesia in Elective Laparoscopic Colorectal Resections
Epidural anaesthesia in open surgery is a effective method for analgesia and has a positive effect on postoperative resolution of ileus. In laparoscopic surgery, the role of epidural surgery is not established.
- Trial name
- NCT00512395
- Testing
- epidural analgesia (Duracain/Fentanyl/Naropin)
- Where
- Switzerland
- Volunteers
- 75 people
- Sponsor
- University Hospital, Basel, Switzerland