Clinical trials: Epidural/Anesthesia
Pre-Eclampsia, Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Electroencephalographic Effects of Spinal Anaesthesia During Caesarean Delivery in Preeclampsia
Neuraxial anesthesia has been associated with delayed brainstem conduction and decreasing afferent sensory transmission, thereby modifying reticulo-thalamo-cortical mechanisms regulating arousal.
- Trial name
- NCT03917342
- Testing
- EEG measure
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Anesthesia, Spinal, Sedation, Conscious
Paradoxical Excitement Response During Sedation Between Dexmedetomidine and Propofol in Hazardous Alcohol Drinker
1. Adequate sedation with classical sedative agents, propofol 2. Sedation with propofol may induce paradoxical excitement response in heavy alcohol drinkers 3.
- Conditions
- Anesthesia, Spinal, Sedation, Conscious, Dexmedetomidine, Alcohol Drinking
- Trial name
- DEX (NCT02197403)
- Testing
- Dexmedetomidine, Propofol
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- Chonnam National University Hospital
Analgesia, Patient-Controlled, Epidural Analgesia
Intrathecal Morphine Analgesia vs. Continuous Epidural Analgesia vs. Systemic Analgesia in Colorectal Surgery.
The purpose of this study is to determine which postoperative analgesia is optimal after colorectal surgery. The investigators will compare intrathecal morphine, continuous epidural analgesia and standard systemic analgesia.
- Conditions
- Analgesia, Patient-Controlled, Epidural Analgesia, Anesthesia; Spinal, Morphine
- Trial name
- KOLORIT (NCT03007121)
- Testing
- Morphine intrathecal, Bupivacaine + Sufentanil epidural, Morphine intravenous
- Where
- Czechia
- Volunteers
- 75 people
- Sponsor
- Charles University, Czech Republic
Epidural Anesthesia, Shivering
The Effect of Oral Pregabalin on Epidural-induced Shivering and Epidural Characteristics
Background: The previous reports tried to reduce shivering and improve neuroaxial anesthesia characteristics by the systemic use of different drugs.
- Trial name
- NCT03721432
- Testing
- Pregabalin 150mg
- Where
- Egypt
- Volunteers
- 77 people
- Sponsor
- Beni-Suef University
Anesthesia, Epidural
Programmed Intermittent Epidural Bolus Versus Continuous Epidural Infusion for Third Trimester Medical Termination of Pregnancy Analgesia : a Randomized Study. (PCEA-IMG)
Background : Recently, delivery of local anaesthetics via Programmed Intermittent Epidural Bolus (PIEB) has been shown to improve labour epidural analgesia compared to delivery via Continuous Epidural Infusion (CEI).
- Trial name
- PCEA-IMG (NCT02563821)
- Testing
- Patient Controlled Epidural Analgesia for third trimester termination of preganancy analgesia, Levobupivacaine, sufentanil
- Where
- France
- Volunteers
- 37 people
- Sponsor
- University Hospital, Limoges
Spinal Anesthesia, Epidural; Anesthesia
Bupivacaine With Epidural Volume Extension
In this study the investigator will address the efficacy of using low dose bupivacaine spinal anesthesia (SA) in combination with epidural volume extension (EVE) for patients undergoing short obstetric procedures.
- Trial name
- NCT03110003
- Testing
- 10 mg Bupivacaine, 5 mg Bupivacaine
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Anesthesia, Epidural, Opioid
Effect of Epidural Opioid Administered in the First A Period on the Progress of Labour
Epidural anesthesia is used to relieve labour pain which helps reduce labour stress, increase comfort and improve cooperation with medical personnel.
- Conditions
- Anesthesia, Epidural, Opioid, Labor Pain
- Trial name
- NCT03344042
- Testing
- Fentanyl, Sufentanil
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- Medical University of Warsaw
Anesthesia; Adverse Effect, Spinal and Epidural
Comparative Study Between Bilateral and Unilateral Spinal Anaesthesia
The purpose of this study is to compare unilateral spinal anesthesia using hyperbaric Prilocaine with "classical bilateral spinal anesthesia" using plain Prilocaine according to block characteristics and quality of micturition…
- Trial name
- NCT01877356
- Testing
- bilateral spinal anesthesia, unilateral spinal anesthesia
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- University Hospital, Antwerp
Analgesia Disorder, Anesthetic Complication Epidural
Effectiveness of Epidural Anesthesia for Thoracic and Abdominal Surgery
This study aims to evaluate the effectiveness of the epidural analgesia in patients having elective thoracic and abdominal surgery under general anesthesia combined with epidural analgesia in Siriraj Hospital.
- Conditions
- Analgesia Disorder, Anesthetic Complication Epidural, Adverse Reaction to Epidural Anesthesia
- Trial name
- NCT02315261
- Testing
- Elective Thoracic and Abdominal Surgery Patients
- Where
- Thailand
- Volunteers
- 364 people
- Sponsor
- Siriraj Hospital
Anesthesia, Epidural, Pregnancy
Study PIEB vs PIEB: the Dose is it Variable According to the Patients
the main objective of this study is to compare the effectiveness of three groups of epidurals with three different programmed intermittent epidural bolus (PIEB)settings.
- Trial name
- DOPABIEB (NCT03690271)
- Where
- France
- Volunteers
- 170 people
- Sponsor
- Rennes University Hospital
Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Correlation Between VCL, AC and Spread of Intrathecal Hyperbaric Bupivacaine in the Term Parturient
Currently there is no guideline to decide on the most appropriate dose of spinal anaesthesia. This study is planned to find out factors that influence the effect of spinal anaesthesia in pregnant mother going for Caesarean…
- Trial name
- NCT03606525
- Testing
- subarachnoid block
- Where
- Malaysia
- Volunteers
- 130 people
- Sponsor
- University of Malaya
Anesthesia, Obstetrical, Analgesia, Epidural
Epidural Analgesia During Labour
Randomized single blind trial based on comparing the way the local anesthetic is dosificated during labour. The pain control is evaluated and compared with both dosage techniques (PCEA vs PIEB)using levobupivacaine and fentanyl.
- Trial name
- PIEBvsPCEA (NCT03133091)
- Testing
- PIEB: Patient Intermittent Epidural Boluses, PCEA: Patient Controlled Epidural Analgesia
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hospital del Rio Hortega
Fetus or Neonate Affected by Maternal Epidural Anesthesia During Labor and Delivery
Pulse Pressure and Post-epidural Fetal Heart Rate Changes
Epidural anesthesia, the most common method of pain control in labor, can contribute to alterations in maternal blood pressure and/or fetal heart rate changes.
- Trial name
- NCT02565485
- Testing
- Lactated Ringer's
- Where
- United States
- Volunteers
- 276 people
- Sponsor
- MetroHealth Medical Center
Anesthesia, Epidural, Analgesia, Epidural
"Compuflo®" in Epidural Space Identification
Recently a computerized injection pump has been programmed with its own mathematical algorithm to measure on a digital display the pressure trend in the form of a continuous curve and it has been connected to an acoustic device…
- Trial name
- NCT03503656
- Testing
- epidural catheter placement
- Volunteers
- 140 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Leg Elevation for Prevention of Post Spinal Hypotension in Cesarean Section
Prospective trial including full term parturients scheduled for a cesarean section under spinal anesthesia. patients are being randomly assigned into 2 groups: LE group: will be positioned in 15° left tilt with leg elevation with…
- Trial name
- NCT03488277
- Testing
- leg elevation
- Where
- Tunisia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mongi Slim Hospital
Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Effect of EPD on the Lumbar Acoustic Window at Term Pregnancy
The purpose of this study is to assess whether application of an epidural positioning device to a parturient seated for neuraxial anaesthesia increase the size of the paramedian target area for neuraxial needle insertion.
- Trial name
- NCT02711150
- Testing
- PLL Length Measured through US
- Volunteers
- 30 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Epidural Anesthesia
Efficacy and Safety of Electric Stimulation-guided Epidural Anesthesia for Cesarean Section
Forty pregnant women (36 to 41 weeks gestation) will randomly allocate to two groups. Groups will be defined based on the method used to identify the epidural space for epidural anesthesia: the loss of resistance group (n=20) and…
- Trial name
- NCT03443466
- Testing
- Epidural electrical stimulation (EES), Loss of resistance (LOR)
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Korea University Guro Hospital
Anesthesia; Adverse Effect, Spinal and Epidural, Anaesthetic Complication Neurological
Neurotoxicity of Spinal Anesthesia With Ropivacaine and Bupivacaine
Consenting patients, scheduled for orthopaedic surgery under spinal anesthesia will be randomly assigned (1:1) to receive ropivacaine or bupivacaine as a single shot before the start of surgery, followed by bolus doses of the…
- Trial name
- BuRoNe (NCT03293472)
- Testing
- Ropivacaine, Bupivacaine
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- University of Rzeszow
Anesthesia, Spinal, Anesthesia, Epidural
Alcohol 70% Versus Chlorhexidine 0.5% in the Spinal Anesthesia Skin Antissepsis
Context: The neuraxial blocks, spinal anesthesia and epidural anesthesia are among the most frequently performed procedures worldwide, and despite the advancements of medical equipment, remain dependent on experience and practice…
- Conditions
- Anesthesia, Spinal, Anesthesia, Epidural, Antisepsis
- Trial name
- NCT02833376
- Testing
- alcohol antisepsis, chlorhexidine antisepsis
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Universidade do Vale do Sapucai
Anesthesia; Adverse Effect, Spinal and Epidural, Hypotension
Ephedrine vs. Nor Epinephrine Infusion in Preventing Hypotension After Spinal Anesthesia for Cesarean Section
The purpose of the study is to determine if norepinephrine is more effective as a continuous intravenous (IV) infusion compared to continuous IV ephedrine associated with crystalloid loading for maintaining blood pressure during…
- Conditions
- Anesthesia; Adverse Effect, Spinal and Epidural, Hypotension, Complications; Cesarean Section
- Trial name
- NCT02477501
- Testing
- Norepinephrine, Ephedrine
- Where
- Tunisia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar