Clinical trials: Epidural/Anesthesia
Vaginal Laceration During Delivery
The PAIN (Pelvic Area Injection for Numbness) Study
Postpartum pain can interfere with patient's ability to care for themselves, and their newborn, and untreated pain is associated with risk of greater opioid use, postpartum depression, and development of persistent pain.
- Trial name
- PAIN (NCT05972681)
- Testing
- Bupivacaine, Epinephrine
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Pain Syndrome, Dizziness
Postoperative Analgesia Between Paravertebral Block and Epidural Block in Esophageal Surgery
Prevention of postoperative pain is essential for the recovery of esophageal surgery. Epidural analgesia is a traditional and standard perioperative pain management for these patients.
- Conditions
- Pain Syndrome, Dizziness, Vomiting, Itching
- Trial name
- NCT06704698
- Testing
- Liposomal bupivacaine, Bupivacaine Hydrochloride
- Where
- China
- Volunteers
- 132 people
- Sponsor
- Zhejiang Cancer Hospital
Postoperative Urinary Retention, Urinary Tract Infections
Comparative Study Between Retained and Non-retained Urinary Catheter in Total Knee Arthorplasty With Epidural Anesthesia
The purpose of this study is to compare the prevalence of postoperative urinary retention between retained and non-retained urinary catheter in total knee arthorplasty with epidural anesthesia
- Conditions
- Postoperative Urinary Retention, Urinary Tract Infections, Epidural Anesthesia
- Trial name
- NCT03341819
- Testing
- Total knee arthroplasty, Urinary Catheterization
- Where
- Thailand
- Volunteers
- 242 people
- Sponsor
- Navamindradhiraj University
Liver Disease, Pain
Comparison Between Epidural and Bilateral Paravertebral Blocks in Liver Resection
This prospective, randomized study is intended to assess the efficacy and safety of bilateral continuous paravertebral blocks compared to continuous epidural block for open liver resection.
- Trial name
- NCT01407666
- Testing
- paravertebral blocks
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Pittsburgh
Low Back Pain, Radiating Pain
Effect of Nitrous Oxide in Treating Neuropathic Pain: A Study in Chronic Low Back Pain Patients
Epidural injection will be completed under fluoroscopy and all patients will receive 1-4 mg of Midazolam for relaxation before procedure and, if needed, 50-100 mcg of Fentanyl intravenous (IV).
- Trial name
- NCT01172600
- Testing
- Entonox, Oxygen
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- The Cleveland Clinic
Fracture; Rib, Multiple
Erector Spinae Plane Block Versus Thoracic Epidural Analgesia in Patients With Multiple Fracture Ribs
To assess the analgesic and respiratory effect of continuous Erector Spinae Plane block versus Thoracic Epidural in patients with multiple fracture ribs.
- Trial name
- NCT03853330
- Testing
- Ultrasound, Bupivacaine HCl Inj 0.25%, Bupivacaine Hydrochloride, 0.125%-0.9% Injectable Solution
- Where
- Egypt
- Volunteers
- 108 people
- Sponsor
- Assiut University
Epidural Analgesia After Major Open Abdominal Surgery
Evaluation of the Performance of Epidural Analgesia After Major Abdominal Surgery
Epidural analgesia is widely used for the treatment of acute postoperative pain, and currently represents the gold standard after open major abdominal surgery.
- Trial name
- PAPCAM (NCT04912557)
- Testing
- postoperative pain assess
- Where
- France
- Volunteers
- 69 people
- Sponsor
- University Hospital, Toulouse
Lower Extremities Fracture
Comparison Between Dexamethasone and Morphine as an Adjuvant to Bupivacaine for Post-operative Analgesia
The study aimed to compare the effectivity of dexamethasone 8 mg and morphine 2 mg as an adjuvant to epidural bupivacaine 0,125% 12,5mg for post-operative analgesia in lower extremities.
- Trial name
- NCT03051022
- Testing
- Dexamethasone 8 mg, Morphine 2 mg
- Where
- Indonesia
- Volunteers
- 64 people
- Sponsor
- Universitas Indonesia
Labor Pain
Epidural Labor Analgesia and Infant Neurobehavior
Infant neurobehavior alteration is predictor of later intelligence development. Many factors would influence or are associated with infant neurobehavior, of which exist or appear during perinatal period.
- Trial name
- ELAIN (NCT00987441)
- Testing
- Ropivacaine and sufentanil
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Nanjing Medical University
Anesthesia, Spinal, Sedation, Conscious
Paradoxical Excitement Response During Sedation Between Dexmedetomidine and Propofol in Hazardous Alcohol Drinker
1. Adequate sedation with classical sedative agents, propofol 2. Sedation with propofol may induce paradoxical excitement response in heavy alcohol drinkers 3.
- Conditions
- Anesthesia, Spinal, Sedation, Conscious, Dexmedetomidine, Alcohol Drinking
- Trial name
- DEX (NCT02197403)
- Testing
- Dexmedetomidine, Propofol
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- Chonnam National University Hospital
Pectus Excavatum, Funnel Chest
Intercostal Nerve Cryoablation Versus Epidural Analgesia for Nuss Repair of Pectus Excavatum
Primary objective of the current study is to determine the impact of intercostal nerve cryoablation on postoperative length of hospital stay compared to standard pain management of young pectus excavatum patients (12-24 years)…
- Trial name
- ICE (NCT05731973)
- Testing
- Intercostal nerve cryoablation, Thoracic epidural analgesia (continuous infusion with sufentanyl (1 µg/ml) and bupivacaine (1.25 mg/ml)), Intercostal nerve block (single shot bupivacaine (1.25 mg/ml))
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Zuyderland Medisch Centrum
Ultrasonographic Evaluation of Epidural Depth in Infants
Evaluation of Skin-to-Epidural Distance at Different Vertebral Levels by Ultrasonography in Infants: A Prospective Observational Study
The goal of this observational study is to learn about the distance between the skin and the epidural space in infants younger than 12 months.
- Trial name
- NCT07847762
- Testing
- Ultrasonographic Assessment of Skin-to-Epidural Distance, Epidural Catheter Placement for Clinical Indications
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul University - Cerrahpasa
Labor Pain, Maternal Hypotension
Lower Limb Compression Prevents Hypotension After Epidural in Labor
The goal of this study is to determine whether the use of sequential compression devices (lower limb compression) can reduce the rate of maternal hypotension after epidural, and therefore reduce the incidence of fetal heart…
- Trial name
- NCT04750486
- Testing
- Sequential compression devices
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Pain
Preoperative Gabapentin for Acute and Chronic Post-thoracotomy Analgesia
One dose of either gabapentin or placebo will be given to patients prior to thoracotomy. Patients will also receive an epidural infusion, intravenous patient-controlled analgesia with fentanyl, oral acetaminophen and intravenous…
- Trial name
- NCT00588159
- Testing
- Gabapentin, Diphenhydramine
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Michelle Kinney
Obesity, Pregnancy
A Trial of the Use of Ultrasound to Aid the Insertion of Combined Spinal Epidural Anaesthesia
The study will establish whether the use of ultrasound scanning with a purpose built probe will aid the insertion of the needles for epidural and spinal anaesthesia for obese women undergoing elective caesarean section The study…
- Trial name
- NCT00166699
- Testing
- ultrasound
- Where
- 5 sites in United Kingdom
- Volunteers
- 42 people
- Sponsor
- NHS Greater Glasgow and Clyde
Labor Pain
Does Having a Spouse Present During Epidural Analgesia Affect Stress Levels in the Parturient and Her Spouse?
It is unclear the effect of a spouse's presence on the partureint's and the spouse's stress level during the performance of epidural analgesia during labor.
- Trial name
- NCT00763126
- Testing
- stress level
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Rabin Medical Center
Surgical Anesthesia, Cesarean Section
Comparison of Chloroprocaine vs Lidocaine for Epidural Anesthesia in Cesarean Delivery
Regional anesthesia is commonly used for elective and emergency cesarean delivery. It provides numerous safety advantages when compared to general anesthesia for both the mother and fetus1.
- Trial name
- NCT03414359
- Testing
- 2% Lidocaine, 3% Chloroprocaine
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Pain, Anesthesia
Drug Concentration and Volume on Adequate Labor Analgesia With PIEB
Neuraxial labor analgesia is performed by the administration of a local anesthetic/opioid mixture in the epidural space. The delivery method is a combination of continuous infusion, provider-administered boluses and…
- Conditions
- Pain, Anesthesia, Labor Pain
- Trial name
- CADD2 (NCT03553576)
- Testing
- Low volume bolus, High volume bolus
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Northwestern University
Bladder Cancer
The Impact of Intrathecal Morphine Versus Continuous Epidural Analgesia on Return of Bowel Function in Patients Undergoing Laparoscopic Ileal Conduit
This study aims to compare the effects of intrathecal morphine (ITM) and continuous epidural analgesia (CEA) on bowel function recovery after Bricker surgery.This study was a prospective, randomized controlled trial that included…
- Trial name
- NCT06688643
- Testing
- ITM group, EA group
- Where
- China
- Volunteers
- 58 people
- Sponsor
- Xiaguang Duan
Colorectal Neoplasms
General Anesthesia Combined With Epidural Anesthesia Mitigates the Surgical Stress-related Immunosuppression in Patients With Colorectal Cancer
The purpose of this study is to prove whether general anesthesia combined with epidural anesthesia could better maintain body balance of Th1/Th2 and Treg/Th17 compared with general anesthesia, so as to reduce the surgical…
- Trial name
- NCT01978717
- Testing
- epidural anesthesia, general anesthesia
- Where
- China
- Volunteers
- 53 people
- Sponsor
- Changhong Miao