Clinical trials: Epidural; Anesthesia
Inguinal Hernia, Circumcision
Analgesia in Children Using Caudal Epidural Ropivacaine
Caudal epidural analgesia (caudal block)is used in standard pediatric anesthesia practice. It has been shown to be effective in managing postoperative pain in children undergoing abdominal and infraumbilical surgery (Tobias et al…
- Trial name
- NCT01494272
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Breastfeeding
Evaluation of Breastfeeding Success and Self-Efficacy in Mothers Giving Birth Via Vaginal Delivery or Cesarean Section
This cross-sectional observational study was conducted to compare breastfeeding success and breastfeeding self-efficacy levels of mothers who gave birth via vaginal delivery (spontaneous or via epidural analgesia) or cesarean…
- Trial name
- NCT05106634
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
General Anesthesia
Effect of Thoracic Epidural Analgesia on Intravenous Closed-Loop Anesthesia
The association of general anesthesia and of thoracic epidural anesthesia is used in thoracic surgery with a demonstrated benefit on the risk of postoperative respiratory complications.
- Trial name
- Drone-APDT (NCT00627081)
- Testing
- remifentanil
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hopital Foch
Epidural; Anesthesia, Catheter Complications
Nylon Versus Polyurethane Epidural Catheters In Patients Undergoing Major Orthopedic Surgery
Objectives: To compare the safety and efficacy of nylon (polyamide) epidural catheter versus polyurethane epidural catheter in patients undergoing major orthopedic surgery under continuous epidural anesthesia.
- Conditions
- Epidural; Anesthesia, Catheter Complications, Catheter Blockage, Catheter Dysfunction
- Trial name
- NCT05168943
- Testing
- Nylon (Polyamide) Epidural Catheter, Polyurethane Epidural Catheter
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Damanhour Teaching Hospital
Labor
Cesarean Rate in Parturients Without Neuraxial Analgesia
Currently, it is certain that neuraxial analgesia in early stage of labor and delivery dose not increase the risk of Cesarean section.
- Trial name
- CRINA (NCT01157325)
- Testing
- Neuraxial analgesia, Non-neuraxial analgesia
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Nanjing Medical University
Free Tissue Flaps
Effect of Epidural Anesthesia on Blood Flow in Arterial Anastomosis of Free Flap
Comparing the changes of arterial anastomotic blood flow between general anesthesia alone and general anesthesia with epidural anesthesia in patients who undergoing free flap transposition using Duplex ultrasound.
- Trial name
- NCT03330808
- Testing
- Epidural anesthesia
- Where
- South Korea
- Volunteers
- 52 people
- Sponsor
- Asan Medical Center
Pain Management, Pain, Postoperative
Preperitoneal Analgesia Versus Epidural Analgesia After Open Pancreaticoduodenectomy
This is a prospective randomized open-label noninferiority trial that compares thoracic epidural analgesia and continuous preperitoneal analgesia after open pancreaticoduodenectomy.
- Trial name
- Pain (NCT04375826)
- Testing
- Epidural patient controlled analgesia, Preperitoneal analgesia and IV-PCA
- Where
- South Korea
- Volunteers
- 146 people
- Sponsor
- Seoul National University Hospital
Anesthesia, Obstetric
Dural Puncture Epidural Technique During Cesarean Section
DPE technique was performed by creating a perforation in the dura mater using a pencil point spinal needle (25-27G) through the shaft of an epidural needle.
- Trial name
- NCT06184425
- Testing
- Dural Puncture Epidural technique using pencil-point 25G Whitacre needle, Dural Puncture Epidural technique using pencil-point 27G Whitacre needle
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Reham Ali Abdelhaleem Abdelrahman
Pregnancy, Epidural Analgesia, Obstetric
Intelligence and Neurodevelopmental Outcome After Prenatal Exposure to Labour Epidural Analgesia: a Sibling Matched Clinical Ambidirectional Cohort Study
In Belgium, labour epidural analgesia (LEA) has been used for decades in the vast majority of vaginal deliveries (up to 83% of deliveries).
- Trial name
- NCT07014956
- Testing
- Labour epidural analgesia
- Where
- Belgium
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Epidural Block in Axial Spondyloarthritis
Ultrasound Guided Epidural Block in Axial SPA
Study Design: A randomized, prospective, pilot, controlled trial. Setting: Rheumatology and rehabilitation department Minia University and Sohag University Objectives: To evaluate the effectiveness of caudal epidural injections…
- Trial name
- NCT04143165
- Testing
- Epidural block with lidocaine and triamcinilone
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Sohag University
Shivering, Labor
Investigating the Effect of Acupressure on Shivering During a Cesarean Delivery in Women Who Were Previously Laboring With an Epidural
Shivering during a cesarean section can be quite uncomfortable for the patient as well as make it difficult for the anesthesiologist to obtain vital signs.
- Conditions
- Shivering, Labor, Cesarean Delivery
- Trial name
- NCT03497507
- Testing
- Acupressure bracelet
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Asepsis, Analgesia, Epidural
Chlorhexidine Versus Povidone-Iodine for Prevention of Epidural Needle Contamination in the Parturient
Infection after epidural catheter placement is fortunately rare. When it does happen, the affected person can become seriously ill.
- Conditions
- Asepsis, Analgesia, Epidural, Anesthesia, Epidural
- Trial name
- NCT00223002
- Testing
- Chlorhexidine
- Where
- Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Bilateral Rectus Sheath Block, Thoracic Epidural Analgesia
Bilateral RSB vs TEA Epidural Analgesia for Postoperative Pain Control After Open Gastrectomy: A Randomized Controlled Trial
Patients indicated for elective open gastrectomy were screened, enrolled, and randomised between October 2021 and September 2023.
- Trial name
- NCT07634731
- Testing
- Bilateral Rectus Sheath Block and Thoracic Epidural Analgesia for Postoperative Pain Control After Open Gastrectomy.
- Where
- Latvia
- Volunteers
- 60 people
- Sponsor
- Igors Ivanovs
Pregnancy, Pain
Safety of Epidural Fentanyl and Adrenalin During Childbirth
Investigation of pharmacokinetic effects of combining fentanyl and adrenalin in the epidural solution given to women in childbirth
- Trial name
- NCT00685672
- Testing
- adrenalin
- Where
- 2 sites in Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Hypotension
Pilot Study: Paravertebral Analgesia vs Epidural Analgesia After Thoracotomy
Paravertebral analgesia is non-inferior to epidural analgesia for pain control and superior to epidural analgesia in terms of the main complication of hypotension.
- Trial name
- ParaEpi (NCT01700491)
- Testing
- Epidural Catheter 0.2% ropivacaine, Paravertebral Catheter 0.4% ropivacaine
- Where
- 2 sites in Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Anesthesia, Local
Epidural Catheter Location by Epidural Pressure Waveform
The aim of this preliminary study was to evaluate the new CompuFlo instrument which allows pulsatile waveform recordings.
- Trial name
- NCT04205773
- Testing
- CompuFlo
- Where
- 2 sites in Italy
- Volunteers
- 30 people
- Sponsor
- European e-Learning School in Obstetric Anesthesia
Analgesia
Epidural Anesthesia /Analgesia Versus PCA for Laparoscopic Complex Ventral Hernia Repair: A Randomized Controlled Trial
We plan to demonstrate the superiority of epidural anaesthesia/analgesia in repairs of large ventral hernias as compared with a conventional narcotic analgesia regimen. We hypothesize that: 1.
- Trial name
- NCT00529074
- Testing
- Epidural Catheter for Analgesia
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Spinal and Epidural Anaesthesia-Induced Headache During Pregnancy
Establishment of a Predictive Model for Post-dural Puncture Headache
The goal of this clinical trial is to establish a predictive model for post-dural puncture headache. The main questions it aims to answer are: Changes in intracranial pressure after spinal puncture (or lumbar puncture).
- Trial name
- NCT06800859
- Testing
- Supplement fluids
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Yilin Zhao
Morbidity, Mortality
Outcome of Patients After Total Knee Replacement: A Comparison of Femoral Nerve Block and Epidural Anesthesia
Total knee replacement is very common in Germany. After surgery patients have severe pain in the knee; initiation of the physiotherapy, however, is important in the first three days after surgery.
- Conditions
- Morbidity, Mortality, Complications, Function
- Trial name
- NCT01631799
- Testing
- Femoral catheter, Epidural catheter
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University of Rostock
Pain, Obesity
Effect of Body Mass Index on the Dose of Intrathecal Hyperbaric Bupivacaine for Elective Cesarean Section
Combined spinal - epidural (CSE) anesthesia is a well established technique used for elective Cesarean section. As its name suggests, it combines two anesthesia techniques - spinal and epidural.
- Trial name
- NCT00403663
- Testing
- bupivacaine 0.75% with fentanyl and morphine
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital