Clinical trials: Error, Refractive
Myopia
Efficacy and Safety of 1% Atropine "5+3" Regimen in Children and Adolescents Controlling Myopia
Studies have shown that atropine eye drops are effective in controlling myopia in children and adolescents. 1% atropine ophthalmic drug has obvious curative effect for controlling myopia, but its side effects such as photophobia…
- Trial name
- NCT05448989
- Testing
- 1% atropine 5+3
- Where
- China
- Volunteers
- 192 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia; Astigmatism
Dispensing Evaluation of Investigational Contact Lenses
Non-randomized, single-masked, 2-visit, bilateral wear, single-arm dispensing study to evaluate the visual acuity, rotational performance, lens fit, stability and subjective characteristics of a senofilcon-based JJVCI…
- Trial name
- NCT02625220
- Testing
- Prototype toric lens senofilcon A
- Where
- 12 sites in United States
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Soft Contact Lenses, Myopia
DAILIES TOTAL1 Versus ACUVUE TruEye - Effects on the Biology of the Ocular Surface and Lid Margin
This is a prospective, single center, randomized, bilateral crossover, dispensing clinical trial to evaluate the effects of the water gradient lens, DAILIES TOTAL1, on the biology of corneal epithelium over two months of daily…
- Trial name
- TruEyeTotal1 (NCT02347631)
- Testing
- Soft Contact Lens - Daily Disposable Alcon Dailies Total 1 and ACUVUE TruEye, Soft Contact Lens - Acuvue TruEye and Alcon DAILIES TOTAL 1.
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Refractive Error
Evaluation of Deposits on Contact Lenses Worn Daily Wear
The purpose of this study was to measure front surface deposits on contact lenses when worn for ten hours.
- Trial name
- NCT00725153
- Testing
- Balafilcon A contact lenses (PureVision), Etafilcon A contact lenses (Acuvue2)
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Alcon Research
Astigmatism
Evaluating and Improving Functional Driving Vision of Patients With Astigmatism: Phase 3
It is a common clinical practice to leave small amounts of astigmatism uncorrected in contact lens wearers. Therefore, some drivers who have astigmatism and wear contact lenses may experience blur while driving.
- Trial name
- NCT02950545
- Testing
- Spherical Lenses, Toric Lenses
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Myopia
Efficacy of Repeated Low-level Red-light Therapy in Myopia Control
Low-level red-light technology provides a new and innovative myopia control approach. This strategy enables relatively high energies of light to be delivered at much shorter durations of exposure to induce the myopia control…
- Trial name
- NCT05606237
- Testing
- Low-level Red Light Therapy Device
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Presbyopia
Clinical Performance of a Phakic Intraocular Lens (IOL)
This study will evaluate the clinical performance of a phakic intraocular lens (IOL) for the improvement of Uncorrected Near Visual Acuity (UCNVA) in subjects who require between +1.00 and +2.50 Reading Add.
- Trial name
- NCT03499821
- Testing
- EDOF ICL
- Where
- 6 sites in Belgium, Spain
- Volunteers
- 41 people
- Sponsor
- Staar Surgical Company
Myopia, Choroidal Neovascularization
Efficacy and Safety of Intravitreal Bevacizumab in the Treatment of Choroidal Neovascular Membranes Associated to High Myopia
The purpose of this study is to determine the efficacy and safety of intravitreal injections of bevacizumab in High Myopia´s choroidal neovascularization versus the standard treatment of Photodynamic therapy.
- Trial name
- NCT00967850
- Testing
- Intravitreal Injection, Photodynamic Therapy (Visudyne)
- Where
- 7 sites in Spain
- Volunteers
- 56 people
- Sponsor
- Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA
Myopia
the Effect of Low-Concentration Atropine Combined With Auricular Acupoint Stimulation in Myopia Control
To compare the effect of myopia control between patients treated with low-concentration atropine eye drops combined with auricular acupoint stimulation and those treated with atropine alone.
- Trial name
- NCT02055378
- Testing
- Atropine, auricular acupoint stimulation
- Where
- Taiwan
- Volunteers
- 73 people
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Refractive Error, Myopia
Silicone Hydrogel Contact Lens Clinical and Comfort Benefits With a Multi-Purpose Disinfecting Solution
The purpose of this study was to compare lens comfort on Day 30 for Air Optix® lenses cared for with OPTI-FREE® PureMoist® (OFPM) Multi Purpose Disinfecting Solution (MPDS) compared to Acuvue® Oasys® lenses cared for with…
- Conditions
- Refractive Error, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT01809197
- Testing
- Lotrafilcon B contact lenses, Senofilcon A contact lenses, OPTI-FREE PureMoist Multi-Purpose Disinfecting Solution (MPDS)
- Volunteers
- 387 people
- Sponsor
- Alcon Research
Myopia
Pilot Study of Neurovision to Improve Vision and Slow Myopia Progression in Children With Myopia
This is a pilot study to assess the effectiveness of Neurovision treatment in the improvement of vision in children being under-corrected and to assess the effectiveness of Neurovision treatment in slowing down myopia progression…
- Trial name
- NCT00348218
- Testing
- NeuroVision
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Singapore National Eye Centre
Astigmatism, Myopia
Visual Outcomes for Toric Efficacy Study
This is a crossover study of two types of contact lenses (toric orthokeratology and soft multifocals). Primary aims are to quantify correction of astigmatism, subjective and objective visual performance, aberrometry, peripheral…
- Trial name
- VOTE (NCT03728218)
- Testing
- Contact lenses (Orthokeratology), Contact lenses (Soft Multifocal)
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Houston
Myopia
Myopia Control With the Multi-segment Lens
The purpose of this study is to determine if the Multiple-Segment (MS) spectacle lens can slow myopia progression in Hong Kong schoolchildren. MS lens is also called Defocus Incorporated Multiple Segments (DIMS) spectacle lens
- Trial name
- NCT02206217
- Testing
- Multiple-Segment spectacle lens
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Cataract, Myopia
Evaluation of Visual Acuity in Myopic Cataract Patients Using Trifocal Intraocular Lens
The PanOptix trifocal IOL is a new trifocal intraocular lens which is proved to provide good range of vision for distance, intermediate and near and good visual quality in cataract patients with normal axial length.
- Conditions
- Cataract, Myopia, Intraocular Lens
- Trial name
- NCT04927117
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Aier School of Ophthalmology, Central South University
Myopia
Efficacy of Chinese Ocular Exercise on Visual Acuity and Ocular Accommodation in Myopic Teenager
To assess whether Chinese ocular exercise is effective in altering distant and near visual acuity, ocular accommodation and visual symptoms in myopic teenager, and thus might have the possibility of slowing myopia progression in…
- Trial name
- NCT01756287
- Testing
- Chinese ocular exercise
- Where
- China
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Myopia
Visual Outcomes and Contrast Sensitivity After Myopic LASIK
Evaluate visual outcomes and contrast sensitivity for subjects undergoing bilateral myopic LASIK procedure using the 200 kHz WaveLight® FS200 Femtosecond Laser and the WaveLight® Allegretto Wave® Eye-Q Laser.
- Trial name
- NCT01746589
- Testing
- bilateral myopic LASIK
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Daniel S. Durrie, MD
Myopia
WaveLight® EX500 Excimer Laser System for the Correction of Myopia Using InnovEyes™ in Conjunction With InnovEyes™ Sightmap
The purpose of this study is to evaluate the safety and effectiveness of the WaveLight EX500 excimer laser system for the correction of myopia with and without astigmatism using InnovEyes in conjunction with InnovEyes sightmap.
- Trial name
- NCT04219891
- Testing
- WaveLight EX500 excimer laser system with InnovEyes sightmap, LASIK, InnovEyes sightmap
- Where
- 9 sites in United States
- Volunteers
- 272 people
- Sponsor
- Alcon Research
Myopia
Performance of DAILIES TOTAL1 Daily Disposable Contact Lenses in Habitual Soft Lens Wearers Who Report Substantial Digital Device Use
The purpose of this study is to evaluate the performance of DAILIES TOTAL1 daily disposable contact lenses with regards to subjective symptoms (comfort, dryness, vision) in lens wearers who use identify themselves as substantial…
- Trial name
- FOX (NCT06308666)
- Testing
- Delefilcon A contact lenses
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Aphakia, Presbyopia
Clareon PanOptix Pro vs. Clareon PanOptix - Study A
The purpose of this study is to evaluate the safety and effectiveness of Clareon™ PanOptix™ Pro Trifocal Intraocular Lens (IOL) compared to Clareon™ PanOptix™ Trifocal IOL.
- Trial name
- NCT06400745
- Testing
- CPO Pro IOL, CPO IOL, Cataract surgery
- Where
- 8 sites in United States
- Volunteers
- 87 people
- Sponsor
- Alcon Research
Refractive Errors
Changes in Angle Kappa and Corneal Back Elevations After Laser in Situ Keratomileusis in Myopic Astigmatism
Refractive errors and corneal astigmatism are associated with changes in angle kappa and corneal back elevation at the thinnest point in Pentacam.
- Trial name
- NCT06166212
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
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