Clinical trials: Erythritol
Periodontitis
Air Polishing as an Adjunct in Non-surgical Periodontal Therapy
Periodontal disease is an infection that causes inflammation and destruction of the tooth supporting structures, and if untreated, will eventually lead to tooth loss.
- Trial name
- NCT04178291
- Testing
- Ultrasonic scaler and Gracey currettes, Air polishing with erythritol powder
- Where
- Malaysia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Peri-implant Mucositis
Treatment of Peri-implant Mucositis and Supportive Peri-implant Therapy
The investigators are evaluating the therapeutic outcomes of two cleaning instruments on treating peri-implant mucositis. Peri-implant mucositis is inflammation around an implant that is limited to only the gum tissue and is…
- Trial name
- NCT06137846
- Testing
- Air-Polish, Ultrasonic
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Healthy Volunteers, Erythritol
SUVY VerSus SAccharose (SUVISA)
Sugar substitutes are increasingly used to reduce sugar intake. SÜVY is a food ingredient combining erythritol and polydextrose.
- Trial name
- SUVISA (NCT07901491)
- Testing
- SÜVY, Sucrose
- Where
- France
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Minerais SAS
Periodontal Pocket
The Use of Erythritol Powder and Metronidazole Gel for the Non-surgical Treatment of Periodontitis
Aim of the present study is evaluate the use of erythritol powder with/without the adjunct of local metronidazole in the treatment of periodontal pockets.
- Trial name
- NCT02023840
- Testing
- metronidazole gel, ultrasonics, erythritol
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Proed, Torino, Italy
Physiological Satiation Mechanisms
Acute Effects of the Two Alternative Sweeteners D-allulose and Erythritol on Metabolism
The aim of this project is to investigate the effect of intragastric (ig) D-allulose on metabolic parameters in general and to investigate the effect of sweet taste receptor blockade on GI hormone responses, glycemic control…
- Trial name
- NCT04027283
- Testing
- Erythritol, Erythritol + lactisole, D-allulose
- Where
- Switzerland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Obesity
Effect of the Natural Sweeteners Erythritol and Xylitol on Gut Microbiota and Glucose Metabolism in Obese Volunteers
Sugar alcohols such as xylitol and erythritol are increasingly popular as sugar substitutes in the food industry and are also recommended to diabetic patients.
- Trial name
- NCT02824614
- Testing
- E967-Xylitol, E968-Erythritol
- Where
- 3 sites in Norway, Russia and 1 more
- Volunteers
- 64 people
- Sponsor
- University Hospital, Basel, Switzerland
Periodontitis
Compare Air Polishing With Ultrasonic During Maintenance
Periodontal disease is a chronic multifactorial inflammatory disease that affects the soft and hard supporting tissues of the teeth.
- Trial name
- NCT04169945
- Testing
- Ultrasonic instrumentation, Air polishing with erythritol powder
- Where
- Malaysia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Periodontitis
Clinical Effects and Metagenomic Analysis of Using an Air Polishing Device With Erythritol Powder Compared to Scaling and Root Planing in Periodontal Maintenance Therapy.
Periodontitis is a chronic, multifactorial disease primarily driven by the accumulation of bacterial deposits. Treatment involves the mechanical removal of the biofilm, traditionally performed by scaling and root planing (SRP).
- Trial name
- NCT07344805
- Testing
- AIRFLOW® Prophylaxis Master, Cavitron® ultrasonic scaler
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Cardenal Herrera University
Dental Caries, Dental Plaque
Effect of Xylitol- Versus Erythritol-Sweetened Mints on Plaque ATP-Bioluminescence Readings
This study will assess the effectiveness of erythritol and xylitol in suppressing biofilm activity, using both within-subject and between-group comparisons.
- Trial name
- NCT07902323
- Testing
- Xylitol, Erythritol
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Obesity
Efficacy of D-allulose on Weight and Fat Loss and Insulin Resistance in Non-diabetic Obese Subjects
Prospective, randomized, double-blind, controlled-trial 30 subjects in each groups Group - I consume pure D-allulose 5 g 3 times a day before meal to right after meal (with any liquid) and Group - II control group with…
- Trial name
- NCT02988999
- Testing
- D-allulose, erythritol
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Periodontal Diseases
Efficacy of Subgingival Erythritol Air Polishing in Treatment of Periodontal Pockets
Periodontitis is an inflammation associated with destruction of the periodontium that ultimately, if not treated, leads to tooth loss.
- Trial name
- NCT05798871
- Testing
- Subgingival erythritol air polishing, Conventional root planing
- Where
- Iraq
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Dental Caries
Effect of Erythritol and Xylitol on Dental Caries Prevention in Children
This study aims at demonstrating the effect of erythritol and xylitol lozenges on preventing the new caries lesions and the possible remineralization effect of both polyols on incipient caries lesions.
- Trial name
- NCT01062633
- Testing
- A, erythritol, xylitol, C, sorbitol
- Where
- Estonia
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Tartu
Peri-Implantitis and Peri-implant Mucositis
Non Surgical Treatment of Periimplantitis
20 consecutive adult implant patients, presenting the signs of peri-implant mucositis (probing depth ≥4 mm combined with bleeding and/or pus on probing) or initial peri-implantitis (probing depth ≥4 mm, bleeding and suppuration…
- Trial name
- NCT02023853
- Testing
- ultrasonic, erythritol, metronidazole gel
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Proed, Torino, Italy
Periodontitis, Adult, Periodontitis, Aggressive
Efficacy of Sub-gingival Air-polishing With Erythritol in the Treatment of Periodontitis
The first step in the management of periodontal disease involves the non-surgical removal of the soft and hard bacterial deposits at all supra- and sub-gingival sites, especially into deep pockets, which can be carried on with…
- Trial name
- GBT2017 (NCT04264624)
- Testing
- Perioflow and Erythritol powder and ultrasonic debridement, Airflow and Erythritol powder and ultrasonic debridement
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Peri-Implantitis
Non Surgical Protocol for Treatment of Peri-implantitis
Peri-implantitis is an important disease entity as a result of its high prevalence and the lack of a standard mode of therapy. Non-surgical therapy of peri-implant disease, especially when bone loss is not high, appears to be…
- Trial name
- NCT03451981
- Testing
- mechanical instrumentation, Er:YAG laser, Air Powder
- Where
- Italy
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Periodontal Diseases
Impact of Full Mouth Erythritol Powder Air Polishing on Systemic Inflammatory Response
Periodontitis (PD) is an inflammatory condition that affects 20%-50% of the total global population, with severe disease occurring in 9.8% of individuals.
- Trial name
- NCT05812391
- Testing
- test, conventional
- Where
- Iraq
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Type 2 Diabetes Mellitus
Dose-Dependent Effects of Erythritol on Endothelial Function in Type 2 Diabetes Mellitus
This study is an open-label pilot designed to examine the dose-dependent effects of erythritol, a zero calorie sweetener, on endothelial function. Twenty-four subjects with type 2 diabetes mellitus will make three study visits.
- Trial name
- NCT01908348
- Testing
- Erythritol
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Boston University
Black Stain, Black Plaque
Air Polishers With Erythritol in the Treatment of Dental Black Stain of Bacterial Origin
Black stains on the teeth, caused by the accumulation of chromogenic microorganisms that produce iron compounds, are more common in the pediatric population and have a negative impact on dental aesthetics and patients'…
- Trial name
- NCT06720168
- Testing
- Erythritol air polisher, Dental prophylaxis with ultrasonic treatment
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Cardenal Herrera University
Cardiovascular Risk Factor
Consumption of Oral Artificial Sweeteners on Platelet Aggregation and Polyol Excretion
The principal goal for the study is to examine whether ingestion of a beverage containing artificial sweeteners alters in vitro platelet aggregation.
- Trial name
- COSETTE (NCT04731363)
- Testing
- xylitol, 30g, erythritol, 30g, xylitol, 5g
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Peri-implant Mucositis
Erythritol Air Polishing in Mucositis Treatment
This study aimed to evaluate the effectiveness of air polishing systems compared to the exclusive use of oral hygiene instruction in the treatment of peri-implant mucositis
- Trial name
- NCT06455306
- Testing
- Air-polishing with erythritol at different time points, Single Air-polishing with erythritol
- Where
- Portugal
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Coimbra