Clinical trials: Erythropoietin
Myocardial Ischemic Reperfusion Injury
Erythropoietin Effect on Ischemic_ Reperfusion Injury in Coronary Artery Bypass Graft Surgery
The aim of this trail is to assess the safety and therapeutic effects of single EPO intervention in different times during coronary surgery in changes of inflammatory response.
- Trial name
- NCT02984111
- Testing
- normal saline, erythropoietin
- Where
- Iran
- Volunteers
- 97 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Chronic Renal Failure
A Study Comparing the Effects of Epoetin Hospira and Epogen/Epoetin Alfa (Amgen) When Administered IV in Patients With Chronic Renal Failure Requiring Hemodialysis and Receiving Epoetin Maintenance Treatment
This study assessed the comparability of the pharmacokinetics (PK) of epoetin following intravenous administration of Hospira Epoetin and Epogen/Epoetin Alfa (Amgen) in patients with chronic renal failure receiving hemodialysis…
- Trial name
- NCT01170078
- Testing
- Epoetin Hospira, Epogen
- Where
- 20 sites in United States
- Volunteers
- 107 people
- Sponsor
- Hospira, now a wholly owned subsidiary of Pfizer
Feeding Intolerance, Necrotizing Enterocolitis
Enteral Granulocyte Colony Stimulating Factor and Erythropoietin Early in Life Increases Feeding Tolerance in Preterm Infants: A Randomized Controlled Trial
With preterm birth, the ingestion of amniotic fluid containing enterocyte trophic factors ceases abruptly. This likely predisposes them to villous atrophy feeding intolerance and necrotizing enterocolitis(NEC) once feedings are…
- Trial name
- NCT01441427
- Testing
- recombinant human G-CSF, and rhEPO, rh G-CSF, rh EPO
- Volunteers
- 93 people
- Sponsor
- Ain Shams University
Type 1 Diabetes, Hypoglycemia
Treatment With Erythropoietin and Cognition During Hypoglycaemia
The purpose of the trial is to determine if erythropoietin (EPO) can enhance cognitive function during hypoglycaemia in patients with type 1 diabetes. Patients with type 1 diabetes will receive one injection of EPO.
- Trial name
- NCT00615368
- Testing
- Epoetin alfa
- Where
- Denmark
- Volunteers
- 11 people
- Sponsor
- Hillerod Hospital, Denmark
Spinal Cord Injury
Evaluation of Tolerability and Efficacy of Erythropoietin (EPO) Treatment in Spinal Shock: Comparative Study Versus Methylprednisolone (MP)
The purpose of this study is to evaluate the tolerability and efficacy of erythropoietin (EPO) treatment in spinal shock in comparison with the methylprednisolone treatment (MP).
- Trial name
- NCT00561067
- Testing
- Erythropoietin, Methylprednisolone
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Niguarda Hospital
Cardiac Complications, Signs and Symptoms
Evaluation of the Effects of L-Carnitine Injection in Patients Undergoing Hemodialysis
This is a study designed to test the hypothesis that treatment with L-carnitine will improve the quality of life and some specific symptoms and signs in patients with renal failure submitted to hemodialysis.
- Conditions
- Cardiac Complications, Signs and Symptoms, Muscle Weakness, Anemia
- Trial name
- NCT00173706
- Testing
- L-Carnitine Injection
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Healthy
To Investigate the Pharmacokinetics of EPORON® and EPREX® After Subcutaneous Administration in Healthy Male Volunteers
This Phase I study is to compare pharmacokinetics, safety and pharmacodynamics of EPORON and EPREX after single subcutaneous administration.
- Trial name
- NCT02580006
- Testing
- EPORON, EPREX
- Where
- South Korea
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Dong-A ST Co., Ltd.
Anemia, Neoplasms
An Observational Study of NeoRecormon (Epoetin Beta) in Cancer Patients With Anemia (FAST)
This observational study will evaluate the clinical benefit of NeoRecormon (epoetin beta) in daily routine practice in cancer patients with anemia.
- Trial name
- NCT01168349
- Testing
- epoetin beta [NeoRecormon]
- Where
- France
- Volunteers
- 1,060 people
- Sponsor
- Hoffmann-La Roche
Transplantation, Kidney
The Effect of Erythropoietin Usage in Renal Function After Kidney Transplantation, in Early Phase, in Contrast to Placebo Group
The study hypothesis is that erythropoietin usage after kidney transplantation, in early phase, can improve the outcome for patients and their graft increasing patient and graft survival.
- Trial name
- NCT00617474
- Testing
- Erythropoietin
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Labbafinejhad Hospital
Anemia, Leukemia
Darbepoetin Alfa Compared With Epoetin Alfa in Treating Anemia in Patients Receiving Chemotherapy for Cancer
RATIONALE: Darbepoetin alfa and epoetin alfa may stimulate red blood cell production and treat anemia in patients who are receiving chemotherapy.
- Conditions
- Anemia, Leukemia, Lymphoma, Lymphoproliferative Disorder
- Trial name
- NCT00070382
- Testing
- darbepoetin alfa, epoetin alfa
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Anemia
Safety and Efficacy of Sustained Erythropoietin Therapy
The purposes of this study are to assess safety, efficacy, and subject satisfaction of EPODURE Biopump (an autologous dermal biopump capable of sustained secretion of therapeutic EPO in the body, using a small tissue explant from…
- Trial name
- NCT00542568
- Testing
- EPODURE (dermal Biopump for erythropoietin)
- Where
- 2 sites in Israel
- Volunteers
- 19 people
- Sponsor
- Medgenics Medical Israel Ltd.
Vitamin C, Oral Administration
Oral Vitamin C Administration on Erythropoietin Dosing Requirement in End-Stage Renal Disease Patients on Regular Hemodialysis
The study aimed to evaluate the safety and efficacy of oral vitamin C administration on erythropoietin dosing requirement in end-stage renal disease patients on regular hemodialysis.
- Conditions
- Vitamin C, Oral Administration, Erythropoietin, End-Stage Renal Disease
- Trial name
- NCT07076108
- Testing
- Normal regimen of treatment of anemia, Vitamin C
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Anemia in Myelodysplastic Syndromes
Treatment of the Anemia of Myelodysplastic Syndromes by the Association of Epoetin Beta and All Trans Retinoic Acid
The purpose of this study is To evaluate the efficacy of association of Erythropoetin (Neorecormon) and ATRA in patients with low risk myelodysplastic syndromes To evaluate the tolerance of this treatment
- Trial name
- NCT00437450
- Testing
- Epoetin/Atra
- Where
- 24 sites in France
- Volunteers
- 99 people
- Sponsor
- Groupe Francophone des Myelodysplasies
Fatigue, Unspecified Adult Solid Tumor, Protocol Specific
Epoetin Alfa in Treating Fatigue in Patients With Advanced Solid Tumors Who Are Not Receiving Chemotherapy
RATIONALE: Epoetin alfa may help improve energy levels and quality of life in patients who have advanced solid tumors. PURPOSE: Randomized clinical trial to study the effectiveness of epoetin alfa in treating fatigue in patients…
- Trial name
- NCT00052221
- Testing
- Epoetin alfa
- Sponsor
- M.D. Anderson Cancer Center
Hypogonadism
Testosterone Replacement in Renal Failure
The purpose of this trial is to evaluate the effect of testosterone replacement in men with renal failure (on dialysis) who also have low testosterone.
- Trial name
- NCT02712944
- Testing
- Testosterone, Saline
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Texas Tech University Health Sciences Center
Anaemia
Anemia Studies in Chronic Kidney Disease (CKD): Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat in Non-Dialysis Subjects Evaluating Hemoglobin (Hgb) and Quality of Life (ASCEND-NHQ)
The purpose of this multi-center study in non-dialysis participants with anemia associated with CKD is to evaluate safety, efficacy and quality of life of daprodustat compared to placebo.
- Trial name
- NCT03409107
- Testing
- Daprodustat (GSK1278863), Iron therapy
- Where
- 168 sites in United States, Argentina and 12 more
- Volunteers
- 614 people
- Sponsor
- GlaxoSmithKline
Erythropoiesis Stimulating Agent Pharmacodynamics
ESAs, Reticulocyte Dynamic and Hemoglobin Variability
Background: In a simulation based on a pharmacokinetic model we demonstrated that increasing the erythropoiesis stimulating agents (ESAs) half-life or shortening their administration interval decreases hemoglobin variability.
- Trial name
- NCT01666301
- Testing
- comparison between darbepoetin alfa and C.E.R.A. and different administration intervals
- Where
- Switzerland
- Volunteers
- 31 people
- Sponsor
- Ospedale Regionale di Locarno
Preterm Infants
Randomized Study of Weekly Erythropoietin Dosing in Preterm Infants
Preterm infants are a risk for multiple transfusions, and the administration of human recombinant erythropoietin (Epo) has been shown to decrease transfusion requirements.
- Trial name
- NCT01235923
- Testing
- three times weekly Epo, weekly Epo
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of New Mexico
Healthy
PK, PD, Safety and Immunogenicity Study of Erythropoietin of Incepta Pharmaceuticals Ltd With Eprex (Janssen-Cilag).
Erythropoietin is a glycoprotein which stimulates red blood cell production. It is produced in the kidney and stimulates the division and differentiation of committed erythroid progenitors in the bone marrow.
- Trial name
- NCT07025681
- Testing
- Erythropoietin alfa
- Where
- Bangladesh
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Incepta Pharmaceuticals Ltd
Anemia, Leukemia
Epoetin Alfa in Treating Anemia in Patients With Solid Tumors
RATIONALE: Epoetin alfa may stimulate red blood cell production and treat anemia in patients with solid tumors. It is not yet known whether epoetin alfa given once a week is more effective than epoetin alfa given once every 3…
- Conditions
- Anemia, Leukemia, Lymphoma, Lymphoproliferative Disorder
- Trial name
- NCT00058331
- Testing
- epoetin alfa
- Where
- 18 sites in United States
- Volunteers
- 365 people
- Sponsor
- Alliance for Clinical Trials in Oncology