Clinical trials: Esophageal Lesion
Barretts Esophagus With Low Grade Dysplasia, Dysplasia
Acetic Acid for the Detection of Esophageal Neoplasms
Barrett's esophagus is a complication of chronic gastroesophageal reflux disease that occurs in up to 10% to 15% of patients with this pathology.
- Conditions
- Barretts Esophagus With Low Grade Dysplasia, Dysplasia, Intestinal Metaplasia
- Trial name
- NCT04054713
- Testing
- Acetic acid chromoendoscopy, Seattle protocol
- Where
- Mexico
- Volunteers
- 76 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Cirrhosis
Study of Two Fasting Procedures Before Gastroscopy: 6 Hours Versus 2 Hours for Clear Fluids
Upper gastrointestinal endoscopy is the key examination for screening for precancerous and cancerous lesions of the esophagus and stomach.
- Trial name
- GASTROPREP (NCT03706846)
- Testing
- fasting
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Esophagus Injury, Atrial Fibrillation
Prevalence and Predictors of Esophageal Thermal Lesions in High-power-Short-duration Ablation of Atrial Fibrillation
Patients with documented atrial fibrillation who were referred to our clinic for catheter ablation will undergo standard HPSD ablation and subsequent esophagoscopy.
- Trial name
- VISUAL-AF (NCT05709756)
- Where
- 2 sites in Germany
- Volunteers
- 263 people
- Sponsor
- Helios Health Institute GmbH
Esophageal Cancer, Squamous Cell
Diagnostic Accuracy of Endocytoscopy for Superficial Esophageal Neoplasia
In recent years, endocytoscopy (EC) has undergone rapid development as an advanced endoscopic technique. Characterized by real-time histological imaging and detection capabilities, EC enables visualization of living cells in the…
- Trial name
- NCT06984055
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Changhai Hospital
Benign Esophageal Lesions
Use of Metal Stents on Benign Esophageal Lesions
The evaluation of using metal stents as medically indicated for the treatment of benign esophageal lesions.
- Trial name
- NCT01238913
- Testing
- Endoscopy
- Sponsor
- University of Florida
Esophageal Neoplasms, Gastric Neoplasm
Prevalence of Sub-epithelial Lesions Among Patients Undergoing EGDs in Egypt
Subepithelial lesions (SEL) are incidentally observed in the stomach of about 0.3% of middle-aged men and women; half of these are neoplastic.
- Conditions
- Esophageal Neoplasms, Gastric Neoplasm, Duodenal Neoplasms
- Trial name
- NCT04622098
- Testing
- Endoscopic ultrasound
- Where
- Egypt
- Volunteers
- 2,000 people
- Sponsor
- Kafrelsheikh University
Mild Dysplasia of Esophagus, Moderate Dysplasia of Esophagus
Performance of White Light, NBI and Iodine Staining Endoscopy in the Diagnosis of Esophageal Lesions
The investigators aim to evaluate the performance of Narrow Band Imaging (NBI) endoscopy in Esophageal Squamous Cell Carcinoma (ESCC) screening, as compared to the currently used White Light Endoscopy (WLE) and Lugol's Iodine…
- Conditions
- Mild Dysplasia of Esophagus, Moderate Dysplasia of Esophagus, Severe Dysplasia of Esophagus, Carcinoma in Situ of Esophagus
- Trial name
- NCT04170257
- Testing
- Endoscopic examination using white light, NBI and iodine staining
- Where
- 5 sites in China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Peking University Cancer Hospital & Institute
Esophageal Cancer, Radiotherapy
Short Course Radiation Therapy in Palliative Treatment of Esophageal Cancer
Aim of the study is to assess efficacy of a short course radiation treatment in patients with symptomatic esophageal malignant lesions
- Conditions
- Esophageal Cancer, Radiotherapy, Palliative Care
- Trial name
- NCT03804203
- Testing
- standard treatment, short course treatment
- Where
- Italy
- Volunteers
- 98 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Esophageal Stricture, Endoscopic Submucosal Dissection
Local Triamcinolone Injection Combined With Fibrin Glue Spray in Preventing Esophageal Stricture After Big-range Endoscopic Submucosal Dissection for Esophageal Early Cancer
Endoscopic submucosal dissection (ESD) is the main treatment for esophageal early cancer. But post-ESD stricture has a serious impact on quality of life.When the lesion range reaches up to 3/4 circumferential mucosal defect or…
- Conditions
- Esophageal Stricture, Endoscopic Submucosal Dissection, Early Esophageal Cancer or Precancerous Lesions Treated With Endoscopic Resection
- Trial name
- NCT06840561
- Testing
- Local triamcinolone injection combined with fibrin glue spray
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Sun Yat-Sen University Cancer Center
Stroke
Coughing in Infratentorial Brain Lesion Patients
To record diaphragm excursion in infratentorial brain lesions patients with dysphagia during coughing and compare them to those with supratentorial brain lesion patients with dysphasia and those with no dysphagia at a university…
- Trial name
- NCT02081040
- Testing
- Not applicable (observational study with no active intervention)
- Where
- South Korea
- Volunteers
- 42 people
- Sponsor
- The Catholic University of Korea
Cardiac Arrhythmias, Atrial Fibrillation
Randomized Study on the Effect of Oesophageal Temperature on the Incidence of Esophageal Lesions After AF Ablation
It's a randomized pilot study to evaluate the incidence of esophageal thermal injury after left atrial ablation for the treatment of atrial fibrillation according to three different strategies of esophageal temperature…
- Conditions
- Cardiac Arrhythmias, Atrial Fibrillation, Esophageal Ulcer
- Trial name
- NCT03645070
- Testing
- multipolar and self expandable thermometer, Single probe thermometer
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital
Atrial Fibrillation
Evaluation of the CIRCA Monitoring System in Prevention of Esophageal Lesions Following RFCA
The purpose of this study is to determine if the use of Circa™ temperature monitoring system during ablation procedures will reduce the risk of esophageal lesions or damage.
- Trial name
- CIRCA-EGD (NCT02467166)
- Testing
- Circa™ Probe
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Diego
Bladder Cancer, Cervical Cancer
Varenicline or Nicotine Patch and Nicotine Gum in Helping Smokers in a Methadone Treatment Program Stop Smoking
RATIONALE: Varenicline, the nicotine patch, and nicotine gum help people stop smoking. It is not yet known whether varenicline is more effective than the nicotine patch given together with nicotine gum in helping smokers quit…
- Conditions
- Bladder Cancer, Cervical Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT00790569
- Testing
- nicotine, varenicline
- Where
- United States
- Volunteers
- 315 people
- Sponsor
- Butler Hospital
Temperature Monitoring, Intraoperative
Clinical Accuracy Validation of the Moni-Patc Temperature Monitoring Patch During Surgery (Compared With Esophageal and Bladder Temperature)
Moni-Patc Temperature Monitoring Patch System, a non-invasive, continuous temperature monitoring device designed to estimate core body temperature by applying a Sensor to the neck.This clinical accuracy validation study aims to…
- Trial name
- Moni-Patch OR (NCT07397065)
- Testing
- Moni-Patc Temperature Monitoring Patch System
- Volunteers
- 30 people
- Sponsor
- Murata Vios, Inc.
Esophageal Varices
Study of Capsule Endoscopy to Determine the Accuracy for Detection of Esophageal Varices
Esophageal capsule endoscopy is sedation-less alternative to upper endoscopy for evaluating esophageal lesions and potentially other upper gastrointestinal lesions.
- Trial name
- NCT01079416
- Testing
- Capsule endoscopy, Esophagogastroduodenoscopy
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of California, Los Angeles
Esophageal Subepithelial Lesions
EUS-CNB Versus EUS-SINK for Diagnosis of Upper Gastrointestinal (UGI) Subepithelial Tumors
This is a single-blinded randomized control trial trying to compare the effectiveness of diagnosis between two techniques employed in tissue sampling for subepithelial tumors (SETs) of the gastrointestinal tract.
- Trial name
- NCT02282111
- Testing
- 22-gauge Procore needle (ProCore, Cook Medical Inc., Winston-Salem, NC), conventional needle-knife sphincterotome (Microknife XL; Boston Scientific Inc, Natick, Mass)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Johns Hopkins University
Lung Neoplasms, Esophageal Lesion
Near-Infrared Perfusion During Minimally Invasive Thoracic Surgery Download
This will be a prospective, (NSR), single-center feasibility study of the Olympus VE2 NIR Imaging System to assess perfusion using NIR during minimally invasive esophagectomy and pulmonary segmentectomy.
- Trial name
- NCT05346380
- Testing
- Olympus VE2 NIR Imaging System, Indocyanine green
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Eosinophilic Esophagitis
Value of Patch Testing in Direct Diet Therapy for Eosinophilic Esophagitis
This study is being done to see if allergy patch testing (APT) can help predict effective dietary therapy in patients with eosinophilic esophagitis.
- Trial name
- EoE (NCT02227836)
- Testing
- Allergy Patch Testing
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Mayo Clinic
Early Gastric Cancer
Screening for Early Gastric Cancer in Shaanxi Province
This study collect the relevant data of local residents over 20 years old in 11 regions of Shaanxi Province, The basic information of the subjects was collected by filling in the questionnaire, and serum helicobacter pylori…
- Trial name
- NCT05291728
- Where
- China
- Volunteers
- 12,500,000 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
GERD (Gastroesophageal Reflux Disease), Throat Disorders
Comparing Two Different Methods of Ablation of Inlet Patches (APC vs RFA)
The goal of this prospective study is to compare 2 different treatment options for the ablation of inlet patches in patients with esophageal symptoms.
- Trial name
- NCT07252180
- Testing
- Argon plasma coagulation (APC), RFA
- Where
- Israel
- Volunteers
- 72 people
- Sponsor
- Assaf-Harofeh Medical Center