Clinical trials: Esophagogastroduodenoscopy
Barrett Esophagus, Esophageal Adenocarcinoma
Efficacy of EsoGuard Assay on Esophageal Surface Cells Collected With EsoCheck vs EGD for the Diagnosis of BE or EAC
The study will assess the performance of the combined system, i.e., the use of the EsoGuard assay (lab developed test) on cells collected using the EsoCheck (501k cleared device) to detect Barrett's Esophagus (BE), with or…
- Conditions
- Barrett Esophagus, Esophageal Adenocarcinoma, Barretts Esophagus With Dysplasia, Barrett's Esophagus Without Dysplasia
- Trial name
- ESOGUARDBE2 (NCT04295811)
- Testing
- EsoGuard (lab assay), Esophagogastroduodenoscopy
- Where
- 35 sites in United States, Netherlands
- Volunteers
- 784 people, healthy volunteers welcome
- Sponsor
- Lucid Diagnostics, Inc.
Endoscopy, Gastrointestinal, Artificial Intelligence
Evaluation of the Clinical Effectiveness of Upper Gastrointestinal Endoscopy Reporting System
The objective of this study is to assess the effectiveness of an AI-based reporting system for upper gastrointestinal endoscopy.
- Trial name
- NCT05851885
- Testing
- AI-based reporting system
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Renmin Hospital of Wuhan University
Anesthesia, Anxiety
Media Use, Anxiety, Sedation, and Recovery in Children Having Upper GI Endoscopy
This observational study will investigate whether problematic digital media use is associated with anxiety in children undergoing a planned upper gastrointestinal endoscopy, a camera examination of the upper digestive tract.
- Trial name
- PMU-ASR-ENDO (NCT07916168)
- Testing
- Problematic Media Use
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Gastric Cancer (GC), Gastric Adenocarcinoma
Costs of Opportunistic Upper Gastrointestinal Endoscopy and the Economic Burden of Gastric Cancer Management
Data will be extracted from routinely collected hospital databases.
- Trial name
- EconROGCAS (NCT07522320)
- Where
- Portugal
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Unidade Local De Saúde Do Norte Alentejano
Anemia, Colon Polyps
Same Day Bidirectional Endoscopies - Does the Sequence of Procedures or Choice of Insufflator Matter?
Upper endoscopies (Esophagogastroduodenoscopies-EGDs) as well as a lower endoscopies (Colonoscopies) are routinely performed by gastroenterologists to assess the lining of patients' upper and lower gastrointestinal tracts using a…
- Trial name
- NCT02635217
- Testing
- Carbon dioxide insufflation, room air insufflation, EGD (Esophagogastroduodenoscopy) before Colonoscopy
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Queen's University
Healthy
Remimazolam Versus Midaszolam for Sedation in Diagnostic Upper Gastrointestinal Endoscopy
The goal of this clinical trial is to compare the efficacy of remimazolam with midazolam in patients undergoing gastrointestinal endoscopy.
- Trial name
- NCT05836545
- Testing
- Remimazolam, Midazolam
- Where
- South Korea
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Premalignant Conditions, Malignant Lesions
To Evaluate the Best Metric for Inspection Time During a Diagnostic and/or Surveillance Upper Gastrointestinal Endoscopy (Age ≥ 18 Years, Informed Consent), Between Total Inspection Time Versus Withdrawal Time, for the Identification of Malignant Lesions
Gastric cancer is the fifth cause of cancer-related mortality worldwide. Gastric carcinogenesis involves the progression from premalignant conditions such as atrophic gastritis and intestinal metaplasia to premalignant lesions…
- Conditions
- Premalignant Conditions, Malignant Lesions, Gastric, Esophageal
- Trial name
- NCT06696209
- Testing
- Analysis of the withdrawal time of the Upper Gastrointestinal Endoscopy, Analysis of the total time of the Upper Gastrointestinal Endoscopy, Upper gastrointestinal endoscopy: Common Practices
- Where
- Portugal
- Volunteers
- 1,290 people, healthy volunteers welcome
- Sponsor
- Portuguese Oncology Institute, Coimbra
Patient Satisfaction, Patient Acceptance of Health Care
VRDD in Upper Gastrointestinal Endoscopy
The demand for gastrointestinal (GI) endoscopy is rising year by year and improving the patient's experience of having the procedure has become an important aim.
- Trial name
- NCT06636292
- Testing
- Virtual Reality Distraction and Disassociation (VRDD) Stage 1, Virtual Reality Distraction and Disassociation (VRDD) Stage 1&2
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- South Tyneside and Sunderland NHS Foundation Trust
Dysphagia, Respiratory Complications
Trial- Dysphagia From ETT or GI Endoscopy
The purpose of this study is to conduct a randomized clinical trial to compare the incidence of dysphagia in patients receiving general anesthesia with and without an endotracheal tube for Upper gastrointestinal endoscopy.
- Trial name
- NCT02460055
- Testing
- endotracheal tube, propofol, Fentanyl
- Volunteers
- healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Healthy Individual
CDSS-assisted UGI Endoscopy vs. Routine Screening Endoscopy
This study aimed to find the CDSS-assisted upper GI endoscopy has clinical benefit compared to conventional routine screening upper GI endoscopy. Investigators will conduct a pilot randomized controlled study.
- Trial name
- NCT05452473
- Testing
- CDSS-assisted upper GI endoscopy, no intervention
- Where
- South Korea
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Chuncheon Sacred Heart Hospital
Barrett Esophagus
Does Laparoscopic Sleeve Gastrectomy Lead to Barrett's Esophagus, 5-year Esophagogastroduodenoscopy Findings: A Retrospective Cohort Study
Introduction Laparoscopic Sleeve Gastrectomy (LSG) is one of the most prevalent approaches to tackle obesity and its co-morbidities.
- Trial name
- NCT04587310
- Testing
- Laparoscopic Sleeve Gastrectomy
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Eliana Al Haddad
Esophagogastroduodenoscopy
Topical Pharyngeal Anesthesia in Sedated Esophagogastroduodenoscopy
At recent, the number of patients who underwent sedated esophagogastroduodenoscopy has been on the increase. For such patients, whether topical pharyngeal anesthesia is needed remains to be controversial.
- Trial name
- NCT03070379
- Testing
- Topical lidocaine pharyngeal anesthesia
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Upper Gastrointestinal Symptoms
Effect of AI Monitoring Blind Spots of EGD on the Inspection Time and Lesion Dection Rate
The goal of this clinic trial is to learn about the effect of AI monitoring blind spots on the inspection time to EGD. Patients are randomly assigned to undergo an EGD with or without the assistance of AI.
- Trial name
- NCT05832411
- Testing
- Endoangle
- Volunteers
- 1,672 people, healthy volunteers welcome
- Sponsor
- Renmin Hospital of Wuhan University
Undergoing Esophagogastroduodenoscopy (EGD)
High Resolution Optical Imaging of the Esophagus Using the NvisionVLE™ Imaging System
This is a single center, single arm, open label observational trial of patients undergoing EGD. The primary objective of this clinical trial is to evaluate the ability of physicians to position the NvisionVLE Optical Probe to…
- Trial name
- NCT02031900
- Testing
- NvisionVLE Imaging System: NvisionVLE Imaging Console, NvisionVLE Optical Probe and Inflation Accessory Kit
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- NinePoint Medical
Fasting
Recommended Clear Fluid Intake Volume at 2 Hours Prior to Esophagogastroduodenoscopy for Adult Patients
Research in developing patient fasting guidelines was developed years ago. On a physiological basis, patients with a longer fasting time may have less residual gastric content and lower risk of pulmonary aspiration.
- Trial name
- NCT04501393
- Testing
- Clear liquid intake
- Where
- Thailand
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Children, Only, Pulmonary Aspiration
Ultrasound for Prediction of Empty Stomach in Infants
Background and Aim: Pulmonary aspiration of gastric content is a serious perioperative complication. What is known about the pediatric patient's fasting time is usually based on parental history alone, but in some situation there…
- Conditions
- Children, Only, Pulmonary Aspiration, Anesthesia, Fasting
- Trial name
- NCT05637918
- Testing
- Group 1 (Patients who recorded as Grade 0), Group 2 ( Patients who recorded as Grade 1)
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Anesthesia Morbidity
HIFLO ENDO-High Flow Nasal Cannula in GI Endoscopy
Millions of patients undergo upper GI endoscopy in the United States each year. A large number of these patients have anesthesia to assist with their comfort during the procedure.
- Trial name
- NCT03028688
- Testing
- High flow nasal cannula oxygen
- Where
- United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Esophagogastroduodenoscopy, Colonoscopy
Residual Gastric Volume in Same Day Versus Split Dose and Evening Before Bowel Preparation
The purpose of this study is to determine residual gastric volume and residual gastric pH in patients undergoing combined EGD and colonoscopy comparing the standard single dose prep with the split dose bowel preparation and same…
- Trial name
- NCT02264249
- Testing
- Esophagogastroduodenoscopy and colonoscopy split dose prep, Esophagogastroduodenoscopy and colonoscopy Evening before colonoscopy prep, Esophagogastroduodenoscopy and colonoscopy Same day prep colonoscopy preparation
- Where
- United States
- Volunteers
- 449 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Virtual Reality, Augmented Reality
Virtual Reality to Reduce Pre-Operative Anxiety
This study aims to test the effectiveness of virtual reality (VR) as a non-pharmaceutical intervention to reduce pain and anxiety in children undergoing various procedures in the Ambulatory Surgery Center (ASC) at CHLA, as…
- Conditions
- Virtual Reality, Augmented Reality, IV Stick, Mask Induction
- Trial name
- NCT04268914
- Testing
- Oculus Go VR, Mira Prism VR
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Anesthesia
Intranasal Dexmedetomidine Versus Intranasal Midazolam as a Premedication in Pediatrics Undergoing Upper GI Endoscopy
compare the effectiveness of intranasal dexmedetomidine and midazolam as a premedication in sedation of preschool children in GI endoscopy
- Trial name
- NCT06181682
- Testing
- Dexmedetomidine, Midazolam
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ain Shams University