Clinical trials: Ethanol
HIV, Alcohol Use Disorder
Alcohol Research in HIV: Relapse Prevention
3-arm type 1 pilot implementation-efficacy trial for people with alcohol use disorders to examine the preliminary effectiveness and feasibility of an adapted 2-session, computerized and person delivered relapse prevention…
- Trial name
- ARCH-RPA (NCT05163301)
- Testing
- Relapse Prevention Intervention
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Johns Hopkins University
Underage Alcohol Use, Smoking, Non-Tobacco Products
Culturally Enhancing a Motivational Interviewing Intervention For Latinx Adolescents
The purpose of this study is to compare two versions of an intervention focused on teaching 10-14-year-old Latina/o adolescent's skills that will decrease the likelihood that they will use tobacco, alcohol, and other drugs.
- Trial name
- NCT03947177
- Testing
- GMIT, GMIT+
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Violence, Alcohol Abuse
Tailored Teen Alcohol and Violence Prevention in the Emergency Room (ER)
This study is designed to address both alcohol misuse and violence among adolescents ages 14-18 seeking care in an urban emergency department (ED).
- Trial name
- NCT00251212
- Testing
- Adapted Motivational Interviewing & Skills Training
- Volunteers
- 3,694 people
- Sponsor
- University of Michigan
Acute on Chronic Liver Failure, Alcoholic Hepatitis
CytoSorb® in Patients With Acute on Chronic Liver Failure
The objective of this study is to assess the safety and performance of the CytoSorb® therapy in patients with Acute on Chronic Liver Failure (ACLF) grade ≥ 2 due to a severe alcohol induced hepatitis (Maddrey DF > 32) and a…
- Trial name
- HepOnFire (NCT05131230)
- Testing
- CytoSorb® treatment
- Where
- 2 sites in Germany
- Sponsor
- CytoSorbents Europe GmbH
Cancer Remission
Study of Health-risk Behaviours (Tobacco, Alcohol or Drug Consumption ; Nutrition ; Sedentary Lifestyle ; Sexual Practices) Among Cancer Survivors
Cancer is now becoming a chronic condition though it was, until a short time ago, a fatal illness. Thus, according to the French national cancer institute, nearly 4 million French people have been diagnosed with cancer in their…
- Trial name
- PREVAC (NCT06215365)
- Testing
- Adult cancer survivors who have completed their heavy treatments
- Where
- France
- Volunteers
- 46 people
- Sponsor
- Hospices Civils de Lyon
Alcoholism
N-acetylcysteine in Alcohol Dependence
The present study is designed to find out if N-acetylcysteine works in reducing alcohol drinking and craving.
- Trial name
- NCT00568087
- Testing
- N-acetylcysteine
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Alcohol Dependence
The Self Match Study: A Study of Informed Choice in the Treatment of Addiction
The purpose of this study is to determine whether patient self-matching (as compared with treatment as usual by expert matching) improves quality of life, retention, and outcome for patients being treated for alcohol problems.
- Trial name
- NCT03278821
- Testing
- Self Match, Expert Match
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Kjeld Andersen
Methanol Poisoning
Methanol Poisoning
This study addresses methyl alcohol intoxications with profound acidosis requiring intensive care treatment. The goal is to contribute both to the improvement of diagnosis and follow-up processes and to the development of…
- Trial name
- NCT06931587
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Kartal City Hospital
Lysosomal Acid Lipase Deficiency, Wolman Disease
Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of Sebelipase Alfa in Children With Growth Failure Due to Lysosomal Acid Lipase Deficiency
This was an open-label, repeat-dose, intra-participant dose-escalation study of SBC-102 (sebelipase alfa) in children with growth failure due to lysosomal acid lipase (LAL) Deficiency.
- Trial name
- NCT01371825
- Testing
- Sebelipase alfa (SBC-102)
- Where
- 7 sites in United States, Egypt and 3 more
- Volunteers
- 9 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Head and Neck Cancer, Lung Cancer
Alcohol and Tobacco Consumption in Patients With Head and Neck or Lung Cancer
This is an multicenter study for preventive and therapeutic strategies for patients with head and neck cancer
- Trial name
- ALTAK (NCT01647425)
- Testing
- physician assessment
- Where
- 3 sites in France
- Volunteers
- 385 people
- Sponsor
- Centre Oscar Lambret
Alcohol Use
The Less is More Study
In this project, the investigators will implement innovations to extend use of Contingency Management (CM) to facilitate alcohol use reduction among people living with HIV (PLWH).
- Trial name
- NCT05153811
- Testing
- Counseling, mHealth
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of Florida
Alcohol Use Disorder
In Hospital IM Naltrexone: A Pilot Study
This is a study in-hospital administration of injectable naltrexone vs. oral naltrexone. This is a pilot study to assess provider's and patient's acceptability to be randomized to oral vs.
- Trial name
- IM-NTX (NCT05087771)
- Testing
- injectable naltrexone, oral naltrexone
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Alcohol Use Disorder
Clinical Trial of Rybelsus (Semaglutide) Among Adults With Alcohol Use Disorder (AUD)
This study is a randomized controlled trial of oral semaglutide among treatment-seeking individuals with AUD. The investigators will randomly assign 50 participants to receive semaglutide (titrated to 7 milligrams (mg) per day)…
- Trial name
- NCT05892432
- Testing
- Semaglutide 3 MG [Rybelsus], Semaglutide 7 MG [Rybelsus]
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Colorado, Denver
Alcohol Use Disorder, Alcohol Dependence
Altering Memories That Increase Risk of Relapse in Alcohol Use Disorders
The purpose of this study is to examine the effects of rapamycin (sirolimus) versus a placebo, an inactive substance, on responses to alcohol cues in individuals with alcohol use disorder.
- Trial name
- NCT03732248
- Testing
- Rapamycin
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Alcoholism
Dietary Fiber Intake in Alcohol-dependent Patients
The alcohol problem affects 7.5% of the population in Europe and represents a major public health problem. Alcoholism is also a major cause of undernutrition.
- Trial name
- NCT03803709
- Testing
- inulin
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Université Catholique de Louvain
Alcohol Use Disorder
A First in Human Study of CMND-100 in Healthy and Alcohol Use Disorder (AUD) Subjects
The primary objective of this study is to find the tolerable dose and characterize the safety and pharmacokinetics/ pharmacodynamics (PK/PD) of single and repeated dose of CMND-100 in Healthy Volunteers (HV) and Subjects with…
- Trial name
- NCT05913752
- Testing
- CMND-100
- Where
- 4 sites in United States, Israel
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Clearmind Medicine Inc.
Domestic Violence, Substance Abuse
Treatment of Intimate Partner Violence and Substance Abuse in a Forensic Setting
Intimate partner violence is a significant societal problem. However, treatment of IPV perpetrators is far from effective, which may be partly due to the fact that the role of substance abuse is not taken into account.
- Trial name
- NCT00847548
- Testing
- substance abuse/domestic violence treatment, CBT addressing partner violence
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- VU University of Amsterdam
Alcoholism, Alcohol Dependence
Drug Treatment for Depressed Alcoholics (Naltrexone/Fluoxetine)
This study will examine the effects of combing naltrexone and fluoxetine (Prozac) versus fluoxetine and placebo in alcoholics with co-occurring major depression.
- Conditions
- Alcoholism, Alcohol Dependence, Depression
- Trial name
- NCT00006204
- Testing
- naltrexone (Revia), fluoxetine (Prozac)
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Emotional Regulation, Alcohol Drinking in College
Just-in-Time Coping Prompts for Reactive Digital Behavior in College Students
This study looks at the moments when college students feel a strong emotional swing, and how those moments relate to reacting online when upset, drinking alcohol, and eating in response to emotions.
- Conditions
- Emotional Regulation, Alcohol Drinking in College, Emotional Eating, Aggression
- Trial name
- REACT (NCT07789314)
- Testing
- Momentary coping prompt, Active control message
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Florida
Bipolar Disorder, Alcohol Abuse/Dependence
Quetiapine in Patients With Bipolar and Alcohol Abuse/Dependence
The abuse of alcohol is especially common in people with bipolar disorder. However, very little is known about the pharmacotherapy of people with both bipolar disorder and alcohol abuse/dependence.
- Trial name
- NCT00223249
- Testing
- Quetiapine
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- University of Texas Southwestern Medical Center
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