Clinical trials: Ethanol Intoxication
Driving Impaired, Alcohol Intoxication
Effects of Cannabis/Alcohol on Driving Performance and Field Sobriety Tests
The overarching aim of this study is to examine the impact of acute cannabis and alcohol administration on driving performance, as well as identify methods for detecting driving under the influence of these substances.
- Conditions
- Driving Impaired, Alcohol Intoxication, Driving Under the Influence, Cannabis Intoxication
- Trial name
- NCT05273658
- Testing
- Cannabis, Alcohol
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Diego
Alcoholic Intoxication, Alcoholism
Screening Evaluation for Studies of the National Institute on Alcohol Abuse and Alcoholism (NIAAA)
This protocol has three purposes: (1) to evaluate subjects for inclusion or exclusion from other NIAAA protocols; (2) to provide a common set of descriptive information that will be available on all NIAAA research subjects; (3)…
- Conditions
- Alcoholic Intoxication, Alcoholism, Healthy
- Trial name
- NCT00001673
- Where
- United States
- Volunteers
- 2,220 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Psychological Stress, Alcohol Intoxication
Stress-motivated Alcohol Use as a Value-based Decision-making Process
The goal of this experimental study is to improve our understanding of the effects of stress on the decision to consume (more) alcohol in regular drinkers.
- Trial name
- NCT06264791
- Testing
- Stress, Alcohol
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Washington
Ethanol Intoxication
Study of Safety and Efficiency of the Drug Reamberin® in the Intensive Care of Patients With Acute Ethanol Intoxication
Acute ethanol intoxication is the most frequent pathologic condition developing in subjects using alcohol. The severity of disorders in acute alcohol intoxication is determined, first of all, by the quantity of consumed alcohol…
- Trial name
- NCT05715723
- Testing
- Reamberin
- Where
- 18 sites in Russia
- Volunteers
- 296 people
- Sponsor
- POLYSAN Scientific & Technological Pharmaceutical Company
Alcohol Intoxication, Sexual Violence
Promoting Prosocial Bystander Behavior in Intoxicated Men: Evaluation of RealConsent2.0
Sexual violence (SV) is a significant public health problem particularly among 18-24 year old populations. A major risk factor for SV is alcohol use, which via its negative impact on cognitive abilities and decision-making acts…
- Conditions
- Alcohol Intoxication, Sexual Violence, Helping Behavior
- Trial name
- NCT04912492
- Testing
- RealConsent1.0, RealConsent2.0, Stress Management
- Where
- 2 sites in United States
- Volunteers
- 667 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Alcohol Intoxication, Intimate Partner Violence (IPV)
Alcohol and Sexual Communication Among Couples in the Laboratory
Intimate Partner Sexual Violence (IPSV) is a significant and understudied public health problem among couples, yet little is known about factors that contribute to IPSV perpetration.
- Conditions
- Alcohol Intoxication, Intimate Partner Violence (IPV), Communication
- Trial name
- NCT06865872
- Testing
- Direct Communication, Indirect Communication, Alcohol (Ethanol)
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Alcohol Drinking, Alcohol Intoxication
Towards a Wearable Alcohol Biosensor: Examining the Accuracy of BAC Estimates From New-Generation Transdermal Technology Using Large-Scale Human Testing and Machine Learning Algorithms
The study will employ a combined laboratory-ambulatory design. Participants will engage in ambulatory assessment over the course of 14 days, wearing biosensors assessing transdermal alcohol concentration (TAC) and providing…
- Trial name
- NCT05692830
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Alcohol Use Disorder
A Dose-Escalation Study to Determine the Maximum Tolerated Dose of Arbaclofen Placarbil in Subjects With Alcohol Use Disorder
This study will determine the maximum tolerated dose (MTD) of arbaclofen placarbil (AP) in the treatment of subjects with Alcohol Use Disorder (AUD). For every two subjects receiving AP, one subject will receive placebo.
- Trial name
- NCT02511886
- Testing
- Arbaclofen Placarbil
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Indivior Inc.
HIV, Acquired Immunodeficiency Syndrome
Primary Care-Based Interventions to Reduce Alcohol Use Among HIV Patients
This randomized clinical trial uses a health plan's electronic medical record (EMR) alcohol screen; and examines innovative behavioral interventions, and their cost effectiveness, for hazardous drinking within a large HIV primary…
- Conditions
- HIV, Acquired Immunodeficiency Syndrome, Alcoholism, Alcoholic Intoxication
- Trial name
- NCT01671501
- Testing
- Motivational Interviewing, Email Feedback, Usual Care
- Where
- United States
- Volunteers
- 614 people
- Sponsor
- University of California, San Francisco
Stress, Physiological, Ethanol Intoxication
Internalized Stress in Relation to Alcohol Consumption
The proposed study uses an experimental design to establish causal support for the role of internalized stress, pertaining to uncertainty with regard to one's sexual orientation, in contributing to heavy drinking behavior.
- Conditions
- Stress, Physiological, Ethanol Intoxication, Distress, Emotional
- Trial name
- NCT06091189
- Testing
- Relevant Trier Social Stressor Test (TSST), Ethanol, Irrelevant Trier Social Stressor Test (TSST)
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Ethanol Intoxication
A Clinical Trial to Evaluate the Safety and Efficacy of ADX-629 in in Subjects With Elevated Ethanol Levels
A Double-Blind Trial to Assess the Interaction Between ADX-629 and Ethanol While Exploring the Safety, Tolerability, and Activity of ADX-629 in Subjects With Elevated Ethanol Levels
- Trial name
- NCT05487404
- Testing
- ADX-629
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Aldeyra Therapeutics, Inc.
Alcoholic Intoxication, Automobile Accident
Responsible Marijuana Sales Practices to Reduce the Risk of Selling to Intoxicated Customers
The new recreational marijuana markets are contributing to polysubstance-impaired driving and other harms, especially when marijuana is used in combination with alcohol, by selling marijuana to obviously-intoxicated customers.
- Conditions
- Alcoholic Intoxication, Automobile Accident, Cannabis
- Trial name
- NCT06235632
- Testing
- Policy and Training Intervention, Usual and Customary Policy and Training (UC-PT) (Control) Condition
- Where
- United States
- Volunteers
- 229 people
- Sponsor
- Klein Buendel, Inc.
Driving Under the Influence, Marijuana Intoxication
Cannabis Impairment Detection Application (CIDA)
Subjects will participate in a 4-visit study protocol in which they will be asked to complete a set of computerized tasks and a 45-minute simulated drive in a driving simulator.
- Conditions
- Driving Under the Influence, Marijuana Intoxication, Alcohol Intoxication
- Trial name
- CIDA (NCT04230460)
- Testing
- Cannabis (High% THC) (Inhaled), Cannabis (Very High% THC) (Inhaled), Alcohol (oral)
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Advanced Brain Monitoring, Inc.
Alcoholic Intoxication
WayToServe Español: Online Responsible Beverage Service Training for Spanish-Speaking Servers
Responsible Beverage Service Training (RBS) has been shown to be effective and recent research by this research team has shown that online RBS training (WayToServe®) was more effective, particularly over time, than usual and…
- Trial name
- WTS-E (NCT03001024)
- Testing
- Implementation of WayToServe Español, Usual and Customary RBS Training
- Where
- 2 sites in United States
- Volunteers
- 79 people
- Sponsor
- Klein Buendel, Inc.
Acute Alcohol Intoxication
Assessing the Safety and Efficacy of FSD-F2R6-A-CP in Volunteers in an Induced State of Alcohol Intoxication
This will be a (2 visit) double-blind, randomized, placebo crossover design clinical study to assess the potential benefits of FSD-F2R6-A-CP versus a placebo by assessing its impact on side effect profiles as well as cognitive…
- Trial name
- METAL-2 (NCT06505239)
- Testing
- FSD-F2R6-A-CP
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Quantum Biopharma
Alcohol Use Disorder, Blood Alcohol Content
Self-estimates and Objective Blood Alcohol Concentration in Emergency Department
Many patients presenting in Emergency Department (ED) present alcohol acute intoxication. Some previous studies in general population found that young people under- or over-estimated of blood alcohol concentration (BAC).
- Trial name
- SEOBACED (NCT03998397)
- Testing
- blood alcohol concentration withdrawal
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Abdominal Injuries, Alcohol Intoxication
Alcohol, Psychoactive Drugs, Analgesics and Evaluation in Penetrating Abdominal Trauma
This prospective observational study aims to evaluate whether alcohol consumption, psychoactive drug use, or prior administration of analgesics affects the clinical evaluation and surgical decision-making process in patients with…
- Conditions
- Abdominal Injuries, Alcohol Intoxication, Substance-related Disorders, Penetrating Abdominal Trauma
- Trial name
- DIRECT (NCT07330349)
- Testing
- Alcohol consumption, Psychoactive substance use, Analgesic administration
- Where
- 2 sites in Colombia
- Volunteers
- 363 people
- Sponsor
- Fundacion Clinica Valle del Lili
Ethanol Intoxication
N-acetylcysteine Reduces Acetaldehyde Levels in Binge Alcohol Drinking
Alcohol hangover (veisalgia) is a fairly common phenomenon. The pathogenesis of veisalgia is not understood and treatment has not yet been established.
- Trial name
- NCT05911282
- Testing
- N Acetylcysteine, Lemon juice
- Where
- Slovenia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Ride Sharing, Alcohol Drinking
The Rise of Ride Sharing Companies and Trends in Impaired Driving Accidents
This will be a retrospective study with data collected from the trauma registry. We plan to complete the data collection and analysis by 12/31/2020. Data on ride sharing will be obtained from the Uber and Lyft websites.
- Conditions
- Ride Sharing, Alcohol Drinking, Alcohol Intoxication, Drug Use
- Trial name
- NCT04564599
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Methodist Health System
Drink Too Much, Drinking, Binge
Group-based Intervention for Club Patrons
The purpose of this study is to develop and test a group-based strategy for encouraging groups of young adults who are engaged in party behaviors at nightclubs to intervene with each other to reduce harms associated with overuse…
- Conditions
- Drink Too Much, Drinking, Binge, Drunk, Drug Use
- Trial name
- NCT03652688
- Testing
- Nightlife Safety Plans (NSP), Fire Safety
- Where
- 2 sites in United States
- Volunteers
- 959 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation