Clinical trials: Ethnic Group
Colorectal Cancer
Community Collaboration to Advance Racial/Ethnic Equity in CRC Screening
The goal of this pragmatic randomized clinical trial is to compare two colorectal (CRC) screening outreach approaches (FIT and Cologuard) in community health centers (CHC) in patients overdue for CRC screening.
- Trial name
- CARES (NCT05714644)
- Testing
- FIT kit Screening Test, Cologuard Screening Test
- Where
- 3 sites in United States
- Volunteers
- 5,127 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Advanced/Metastatic Solid Tumors With KRAS p.G12C Mutation
AMG 510 Ethnic Sensitivity Study (CodeBreaK 105).
To evaluate safety, tolerability, PK, and preliminary efficacy of AMG 510 PO QD in subjects of Chinese descent with KRAS p.G12C-mutant advanced/metastatic solid tumors.
- Trial name
- NCT04380753
- Testing
- AMG 510
- Where
- 4 sites in Hong Kong, Taiwan
- Volunteers
- 12 people
- Sponsor
- Amgen
Smoking Cessation
Addressing Racial/Ethnic Tobacco Health Disparities Via Group Intervention
The purpose of this study is to test the effects of a group smoking cessation program. The study will also examine individual differences in response to the intervention program.
- Trial name
- NCT02511236
- Testing
- Group Cognitive Behavioral Therapy, General Health Education, Transdermal Nicotine Patch
- Where
- 2 sites in United States
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- University of Miami
Characteristics That Modify the Response to Cholecalciferol Treatment
Individualized Response to Vitamin D Treatment Study
The goal of this clinical trial is to determine individual-level genetic and metabolic characteristics that modify the response to cholecalciferol treatment.
- Trial name
- INVITE (NCT02925195)
- Testing
- Vitamin D3
- Where
- 5 sites in United States
- Volunteers
- 666 people
- Sponsor
- University of Washington
Healthy
PK Study of Xevinapant (Debio 1143) in Healthy East Asian Participants
The purpose of this study was to evaluate the pharmacokinetics (PK) of Xevinapant (Debio 1143) and its metabolite D-1143-MET1 as well as safety and tolerability of Xevinapant (Debio 1143) in healthy East Asian participants.
- Trial name
- NCT05519540
- Testing
- Xevinapant (Debio 1143)
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Hypertension in Pregnancy, Preeclampsia
Response to Anti-hypertensives in Pregnant and Postpartum Patients
In this study, the investigators will evaluate the blood pressure response to nifedipine and labetalol in pregnant and postpartum patients, who present with hypertensive disease in pregnancy with severe range blood pressure…
- Trial name
- NCT03506724
- Testing
- Nifedipine, Labetalol
- Where
- 2 sites in United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Alzheimer Disease
Alzheimer's PET Imaging in Racially/Ethnically Diverse Adults
The study employs tau positron emission tomography (PET) imaging in a well-characterized multi-racial/ethnic cohort to examine the extent to which tau pathology is associated with cognition, differences in tau pathology across…
- Trial name
- NCT03706261
- Testing
- 18F-MK-6240, 18F-Florbetaben
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Adam Brickman
Mental Health
Building Infrastructure for Community Capacity in Accelerating Integrated Care
Although the Affordable Care Act (ACA) expanded Medicaid eligibility, Medicaid expansions do not appear to have decreased the gap in mental health treatment between Whites and racial/ethnic or linguistic minorities.
- Trial name
- NCT04092777
- Testing
- Strong Minds, Enhanced Usual Care
- Where
- 2 sites in United States
- Volunteers
- 1,044 people
- Sponsor
- Massachusetts General Hospital
Healthy
Ethnic Differences in Response to Topical Capsaicin: A Psychophysical Study on Healthy Subjects
The purpose of this research is to study how people respond differently to capsaicin in different racial groups and the effect it has on your pain levels.
- Trial name
- NCT00655811
- Testing
- Capsaicin
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wake Forest University
No Specific Condition. Feasibility of Mobile App
Exploring the Experience of Using a Prayer Mobile App
The goal of this clinical trial is to explore the feasibility and preliminary effects of using Pray.com on spiritual well-being and mental health symptoms in racial/ethnic minority adults.
- Trial name
- NCT05626673
- Testing
- Prayer app
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Biola University
Healthy
Visualizing Dermal Micropores With OCT
The study to be performed will allow visualization of skin micropores following microneedle treatment in healthy subjects in differing racial/ethnic backgrounds.
- Trial name
- NCT04867733
- Testing
- Micropatch (microneedle patch)
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Type 2 Diabetes Mellitus
Insulin Glargine at Bedtime or in AM Versus NPH
To compare the efficacy and safety of once-nightly insulin glargine versus a single morning injection of glargine or once-nightly NPH insulin in ethnic minority type 2 diabetic patients inadequately controlled on combination oral…
- Trial name
- NCT00686712
- Testing
- 1- Insulin glargine QHS, 2 - Insulin glargine QAM, 3 - NPH insulin QHS
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Charles Drew University of Medicine and Science
Depression in Old Age
PEERS Plus mHealth Enhanced Peer Support
The goal of this intervention study is to design and learn whether peer support that is delivered through video chats and texts can decrease depression among older adults.
- Trial name
- Peers plus (NCT05611996)
- Testing
- Peers plus
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Massachusetts General Hospital
Type 2 Diabetes Mellitus
Insulin Glargine Versus Twice-Daily NPH
To compare the efficacy and safety of once-nightly insulin glargine versus twice-daily NPH insulin in ethnic minority type 2 diabetic patients inadequately treated with once-nightly NPH insulin alone.
- Trial name
- NCT00687453
- Testing
- Insulin glargine at bedtime instead of NPH, NPH twice-daily
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Charles Drew University of Medicine and Science
Anxiety, COVID-19 Pandemic
SMILE: Clinical Trial to Evaluate Mindfulness as Intervention for Racial and Ethnic Populations During COVID-19
The goal of this clinical trial is to evaluate the SMILE app, a Digital Health Platform (DHP), that will deliver a mindfulness intervention, designed to mitigate COVID-19 related stress.
- Trial name
- SMILE (NCT06242080)
- Testing
- Mindfulness
- Where
- United States
- Volunteers
- 398 people
- Sponsor
- University of North Carolina, Chapel Hill
Tissue and Organ Procurement, Alcohol Abstinence
Intervention to Motivate Teens to be a Designated Organ Donor on Driver's License
This study will test the effectiveness of a multimedia campaign to educate ethnic minority teens about the choice to become a designated organ donor on their first driver's license.
- Trial name
- Idecide (NCT00810901)
- Testing
- Organ Donor, Alcohol Prevention
- Where
- United States
- Volunteers
- 429 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Healthy Volunteers From Racial/Ethnic Minority Populations
EXPLORER PET/CT: Evaluation of Healthy Individuals From Racial/Ethnic Minority Populations
The objective of this pilot study is to collect preliminary data using total body scans on a new, first of its kind, FDA 510k-cleared positron emission tomography/computed tomography (PET/CT) scanner, called EXPLORER.
- Trial name
- NCT04812080
- Testing
- EXPLORER PET/CT
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Smoking Cessation, Smoking Tobacco
Proactive Tobacco Treatment for Veterans
Tobacco use is the leading cause of premature death in the United States and disproportionately affects Veterans and certain racial/ethnic minority groups.
- Trial name
- NCT00608426
- Testing
- Proactive Outreach with choice of telephone or in-person smoking cessation services
- Where
- 5 sites in United States
- Volunteers
- 6,400 people
- Sponsor
- US Department of Veterans Affairs
Obesity
Peer-Led Healthy Lifestyle Program in Supportive Housing
This goal of this randomized controlled effectiveness trial is to compare the effectiveness of a peer-led health lifestyle intervention (Peer GLB) versus usual care services in supportive housing agencies in New York City and…
- Trial name
- NCT02175641
- Testing
- Peer-Led Group Lifestyle Balance, Usual Care Services
- Where
- United States
- Volunteers
- 314 people
- Sponsor
- Washington University School of Medicine
Healthy
Racial/Ethnic Differences in Microneedle Response
The study to be performed will define the rate of skin barrier recovery following microneedle treatment of the skin in healthy subjects of differing racial/ethnic backgrounds.
- Trial name
- NCT03332628
- Testing
- Microneedle patch
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Iowa