Clinical trials: Etiology
Shivering Caused by Spinal Anesthesia
COMPARISON OF INTRAVENOUS DEXMEDETOMEDINE AND TRAMADOL FOR POST OPERATIVE SHIVERING AFTER SPINAL ANESTHESIA FOR CAESAREAN SECTION
To compare the mean time of cessation of post-operative shivering after receiving intravenous dexmedetomidine versus tramadol in patients undergoing caesarean delivery under spinal anaesthesia.
- Trial name
- NCT07332572
- Testing
- Tramadol, Dexmedetomidine
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Liaquat National Hospital & Medical College
OHS, Hypercapnic Respiratory Failure
Cardiac and Respiratory Function With Non-invasive Ventilation
To assess patients with hypercapnic respiratory failure using echocardiography,cardiac output measurements and markers of neural respiratory drive (EMGpara) prior to, during and after non-invasive ventilation (NIV) initiation…
- Trial name
- CARE-NIV (NCT02699112)
- Testing
- Parasternal EMG (EMGpara) and Transthoracic Echocardiography
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Chronic Kidney Disease 5D, Secondary Hyperparathyroidism Due to Renal Causes
A Study on Prevention Strategies for CKD-SHPT and Related Complications Based on General Vitamin D Supplementation
1. Study content: This is a multicentre, double-blind, randomised controlled study to determine the optimal dose and duration of treatment for the correction of vitamin D insufficiency or deficiency in patients with CKD5d; to…
- Conditions
- Chronic Kidney Disease 5D, Secondary Hyperparathyroidism Due to Renal Causes, Vitamin D Deficiency
- Trial name
- NCT05549154
- Testing
- High-dose vitamin D2 softgels, low-dose vitamin D2 softgels
- Where
- China
- Volunteers
- 372 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Macular Edema Caused by Retinal Vein Occlusion
Dexamethasone-implant for the Treatment of RVO
To evaluate the efficacy and safety of a dexamethasone-implant alone or in combination with bevacizumab. 64 eyes are prospectively investigated.
- Trial name
- NCT01767545
- Testing
- Dexamethasone implant, Bevacizumab
- Where
- Germany
- Volunteers
- 64 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Short Stature, Growth Disorder
Genetic Causes of Growth Disorders
Background: Some growth disorders are caused by a change in genes. Genes are the instructions the body uses to function. Changes in genes often cause them not to work correctly.
- Conditions
- Short Stature, Growth Disorder, Syndromic Growth Disorder, Tall Stature
- Trial name
- NCT02311322
- Where
- United States
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
HIV Infections, Cytopenias
The Safety and Effectiveness of r-HuEPO in Patients With AIDS and Anemia Caused by AIDS and Treatment With AZT
To determine the safety and efficacy of erythropoietin administered subcutaneously to AIDS patients with anemia secondary to their disease and/or concomitant zidovudine (AZT) therapy.
- Trial name
- NCT00002302
- Testing
- Epoetin alfa
- Where
- 2 sites in United States
- Sponsor
- Ortho Pharmaceuticals
HPV in Testis Tissue
HPV as a Possible Cause of Azoospermia
Azoospermia is found in 5-20% of all men suffering from infertility, and in more than 20% azoospermia remains unexplained. The investigators suggest, that HPV may be an etiological factor in azoospermia and reduced sperm…
- Trial name
- NCT02329275
- Testing
- Testicular biopsy
- Where
- Denmark
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Hypercalcemia
Causes, Characteristics and Treatment of Hypercalcemia in the Emergency Room of a German Hospital
Patients with hypercalcemia were identified in the patient population of a German emergency department during a 11 year time period and studied regarding reproducibility of elevated calcium values, causes of hypercalcemia…
- Trial name
- NCT06467877
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University of Cologne
Coronary Artery Disease
ABSORB II Randomized Controlled Trial
Prospective, randomized (2:1), active control, single blinded, parallel two-arm, multi-center clinical investigation using Abbott Vascular ABSORB Everolimus Eluting Bioresorbable Vascular Scaffold System (ABSORB BVS); compared to…
- Trial name
- ABSORB II (NCT01425281)
- Testing
- Abbott Vascular XIENCE Everolimus Eluting Coronary Stent System, Abbott Vascular ABSORB Everolimus Eluting Bioresorbable Vascular Scaffold System
- Where
- Belgium
- Volunteers
- 501 people
- Sponsor
- Abbott Medical Devices
X-Linked Retinitis Pigmentosa
Clinical Evaluation of Patients With X-linked Retinitis Pigmentosa (XLRP)
The purpose of this study is to evaluate subjects with X-linked retinitis pigmentosa caused by RPGR-ORF15 mutations in a clinical setting to fully characterize their condition, measure testing variability, and estimate rates of…
- Trial name
- NCT03314207
- Where
- 3 sites in United States
- Volunteers
- 14 people
- Sponsor
- Beacon Therapeutics
Renal Failure, Nutrition Disorders
Etiology, Epidemiology and Prognostics of Acute Kidney Injury (AKI)
To investigate the etiology, epidemiology and prognostic factors of acute kidney injury. To find out risk factors that relate with the prognosis of acute kidney injury,focusing on inflammation, oxidative stress and nutritional…
- Trial name
- NCT00953992
- Where
- China
- Volunteers
- 651 people
- Sponsor
- Huashan Hospital
Nocturnal Enuresis, Nocturnal Enuresis in Children
Causes and Types of Nocturnal Enuresis in Children
Nocturnal enuresis, commonly known as bedwetting, is a frequent condition that affects many children and can have a significant impact on their self-esteem, social life, and family stress.
- Conditions
- Nocturnal Enuresis, Nocturnal Enuresis in Children, Primary Nocturnal Enuresis, Secondary Nocturnal Enuresis
- Trial name
- NCT07508111
- Volunteers
- 80 people
- Sponsor
- Assiut University
Nephrogenic Fibrosing Dermopathy, Nephrogenic Systemic Fibrosis
Plasmapheresis for Nephrogenic Fibrosing Dermopathy (NFD)/Nephrogenic Systemic Fibrosis (NSF)
The purpose of this study is to evaluate the pathophysiology of nephrogenic fibrosing dermopathy (NFD)/nephrogenic systemic fibrosis (NSF).
- Trial name
- NFD (NCT01078987)
- Testing
- Plasmapheresis
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Acute Respiratory Distress Syndrome
Safety and Preliminary Clinical Activity of Itolizumab in ARDS
To evaluate the safety, tolerability, PK, PD, and clinical activity of Itolizumab in subjects with acute respiratory distress syndrome (ARDS) caused by Infectious Pneumonia.
- Trial name
- NCT05978544
- Testing
- Itolizumab
- Volunteers
- 38 people
- Sponsor
- Biotech Pharmaceutical Co., Ltd.
Non-small Cell Lung Cancer
the Prevention of Bone Marrow Suppression Caused by Chemotherapy in Advanced NSCLC With Trilaciclib
This study is a single arm, exploratory clinical study aimed at evaluating the efficacy and safety of tralazili before chemotherapy in patients with NSCLC.After pathological diagnosis of non-small cell lung cancer(NSCLC), 40…
- Trial name
- NCT06370416
- Testing
- Trilaciclib
- Where
- China
- Volunteers
- 41 people
- Sponsor
- Henan Cancer Hospital
Hepatitis C, Chronic, Disease Progression
Prospective Observational Study of Disease Progression in Chronic Hepatitis C
The purpose of this study is to determine the progression of chronic hepatitis C patients infected by paid plasma donation,and explore the possible pathogenic mechanisms of disease progression in chronic hepatitis C.
- Conditions
- Hepatitis C, Chronic, Disease Progression, Liver Cirrhosis
- Trial name
- NCT02011932
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Beijing YouAn Hospital
Heart Failure and Reduced Ejection Fraction, NYHA Class III Heart Failure
Propensity-Matched Study of Cardiac Contractility Modulation Therapy in Heart Failure
The purpose of this prospective, multi-center, propensity-matched coverage with evidence development (CED) study is to assess the impact of cardiac contractility modulation (CCM) on mortality and heart failure hospitalizations in…
- Trial name
- BRIGHTEN-HF (NCT07209098)
- Testing
- Cardiac Contractility Modulation (CCM)
- Where
- United States
- Volunteers
- 4,200 people
- Sponsor
- Impulse Dynamics
Cerebellar Atrophy, Etiology
Development, Application, and Mechanistic Investigation of a Novel Minimally-Invasive Bidirectional Epidural Cerebellar Stimulation Technique for Cerebellar Cognitive Affective Syndrome
Building on previous findings regarding microglial immune function and the immunosuppressive effects of glucocorticoids, this project centers on the cerebellum's role in cognitive science.
- Conditions
- Cerebellar Atrophy, Etiology, Physiopathology
- Trial name
- NCT07166432
- Testing
- observational diagnostic model development
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University First Hospital
Acute Myeloid Leukemia
Functional Role of RUNX1 Mutations in the Etiology of Acute Myeloid Leukemia (AML)
The purpose of this study is to elucidate the role of RUNX1 in Acute Myeloid Leukemia (AML), in particular, the transcriptional regulation of genes by mutated forms of this protein.
- Trial name
- NCT01329471
- Where
- Israel
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Pediatric Epilepsies
Natural History and Prognosis of Pediatric Epilepsies With Different Etiology
Epilepsy is one of the most common neurological diseases in Italy, affecting about 500,000 people. Pediatric age represents one of the most affected groups with a consequent significant impact on the quality of life of the…
- Trial name
- NCT07588971
- Where
- Italy
- Volunteers
- 2,300 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.