Clinical trials: Etiology
Anemia
Etiology of Anemia
This study looks at the causes of anemia in adults of all ages who are referred by their primary care physician.
- Trial name
- NCT00302939
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- National Institute on Aging (NIA)
Healthy
Quantitative Evaluation of Skin Shrinkage Caused by a Non-invasive Tightening Device
This study is being done to measure the amount of skin shrinkage caused by a non-invasive skin tightening device.
- Trial name
- NCT00894244
- Testing
- Radiofrequency device
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Complication of Anesthesia
Incidence and Etiology of Complications Associated With Peripheral Nerves Blocks
Procedures performed under regional anesthesia, especially peripheral nerve blocks (PNB) have increased markedly in recent decades. However, like any technical procedure, these techniques carry an implicit risk of complications.
- Trial name
- CARE (NCT05682300)
- Testing
- peripheral nerve block
- Where
- Spain
- Volunteers
- 1,390 people
- Sponsor
- Hospital del Rio Hortega
Out-Of-Hospital Cardiac Arrest, Pediatric Disorder
Etiology, Incidence and Survival of Pediatric Out-of-hospital Cardiac Arrests: a Four-year Danish Analysis
Background: OHCA is a rare condition for children and young adults. Overall incidence rates are reported as 3.3-5.97 per 100.000 inhabitants.
- Conditions
- Out-Of-Hospital Cardiac Arrest, Pediatric Disorder, Cardiopulmonary Arrest
- Trial name
- Child-OHCA (NCT04275856)
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Emergency Medical Services, Capital Region, Denmark
Ischemic Stroke at a Young Age
The Norwegian Stroke in the Young Study II
NOR-SYS II is designed for finding the cause of acute ischemic stroke lesions in Young adults, age 15 to 49 years. Risk factors, arterial wall changes by intima-media thickness and plaques and consequences of stroke are examined…
- Trial name
- NOR-SYSII (NCT02762396)
- Where
- Norway
- Volunteers
- 130 people
- Sponsor
- Haukeland University Hospital
Pulpitis, Acute Pain
Effect of Low Power Laser in Tooth Pain Modulation Caused by Irreversible Inflammation
Anxiety, pain and discomfort are common stressful situations that occur during the dentistry practice, especially in the urgency endodontic practice.
- Trial name
- NCT02169102
- Testing
- No additional Intervention (control), Laser 1 (at 0,16 Joules/point of irradiation), Laser 2 (1,6 Joules/point of irradiation)
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Nausea, Vomiting
Diphenhydramine, Lorazepam, and Dexamethasone in Treating Nausea and Vomiting Caused By Chemotherapy
RATIONALE: Diphenhydramine, lorazepam, and dexamethasone may help lessen or prevent nausea and vomiting in patients treated with chemotherapy.
- Conditions
- Nausea, Vomiting, Unspecified Childhood Solid Tumor, Protocol Specific
- Trial name
- NCT00429702
- Testing
- Decadron®, Benadryl®, Ativan®
- Where
- 7 sites in United States, Puerto Rico
- Volunteers
- 7 people
- Sponsor
- University of South Florida
Necrotizing Enterocolitis, Necrotizing Enterocolitis of Newborn
Infant Formula Feeding and Necrotizing Enterocolitis in Newborns
Necrotizing enterocolitis (NEC) is the most common life-threatening gastrointestinal emergency of prematurity, associated with a significant morbidity and mortality.
- Conditions
- Necrotizing Enterocolitis, Necrotizing Enterocolitis of Newborn, Sepsis Newborn, Cows Milk Allergy
- Trial name
- NCT05121753
- Testing
- Survey investigating Infant formula feeding in newborns
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Neuroganics LLC
Nausea and Vomiting, Chemotherapy-Induced
A Study of the Drug Casopitant for the Prevention of Nausea Caused By Cisplatin-Based Highly Emetogenic Chemotherapy
This is a Phase III trial designed to demonstrate that casopitant when added to dexamethasone and ondansetron is more effective in the prevention of vomiting then dexamethasone and ondansetron alone, in patients who receive a…
- Trial name
- NCT00431236
- Testing
- Oral Casopitant (GW679769), IV Casopitant (GW679769), IV ondansetron hydrochloride
- Where
- 80 sites in Argentina, Belgium and 20 more
- Volunteers
- 810 people
- Sponsor
- GlaxoSmithKline
Phlebitis
Peripheral Venous Catheter Trial: 3 Day Versus No Routine Change
The purpose of this study is to investigate the effects of extending the dwell time of peripheral intravenous cannulas on clinical outcomes and cost.
- Trial name
- NCT00103636
- Testing
- Extending peripheral intravenous (IV) cannula dwell times
- Where
- Australia
- Volunteers
- 200 people
- Sponsor
- Royal Brisbane and Women's Hospital
Schizophrenia
Aripiprazole Once-monthly Versus Daily Oral Atypical Antipsychotic Treatment in Patients With Recent-onset Schizophrenia
This is an observational, non-interventional study that will include two cohorts of patients with schizophrenia who initiated maintenance treatment during a schizophrenia-related hospitalisation or during the immediate three…
- Trial name
- NCT03130465
- Where
- 67 sites in France, Germany and 2 more
- Volunteers
- 636 people
- Sponsor
- Otsuka Pharmaceutical Europe Ltd
Periodontal Disease
Towards a Viral Etiology of Periodontal Disease in Relation to Radiotherapy Treatment of Head and Neck Cancers
The treatment of otolaryngology (OLR) cancer is based on surgery, radiation, sometimes used in combination with chemotherapy. Patients treated with radiotherapy have multiple oral diseases: mucositis, hyposalivation, tissue…
- Trial name
- NCT02180932
- Testing
- periodontal pocket samples
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Peripheral Sensory Neuropathy of Different Etiologies
A Prospective Clinical Trial to Evaluate the Efficacy and Safety of Neurotropic B-Vitamins in Clinically Diagnosed Peripheral Sensory Polyneuropathy of Different Etiologies.
This study is designed to investigate the efficacy of the Test Product in subjects with clinically diagnosed peripheral sensory polyneuropathy of different etiologies compared to placebo.
- Trial name
- NCT05619328
- Testing
- Vitamin B combination tablet
- Where
- Mexico
- Volunteers
- 323 people
- Sponsor
- Procter and Gamble
Anemia, Iron Deficiency, Hyperphosphatemia
Ferric Citrate for the Prevention of Renal Failure in Adults With Advanced Chronic Kidney Disease
A 9-month randomized, double-blind, placebo-controlled study to compare the effect of fixed dose ferric citrate versus placebo in patients with advanced chronic kidney disease (eGFR ≤20 ml/min/1.73m2) on the composite endpoint of…
- Conditions
- Anemia, Iron Deficiency, Hyperphosphatemia, Renal Insufficiency, Chronic, Renal Anemia
- Trial name
- FRONTIER (NCT05085275)
- Testing
- Ferric Citrate 1 GM Oral Tablet [AURYXIA]
- Where
- 23 sites in United States
- Volunteers
- 289 people
- Sponsor
- USRC Kidney Research
Osteoarthritis, Hip Osteoarthritis
MRgFUS in the Treatment of Hand and Hip Osteoarthritic Pain
This project aims at performing a pilot study to provide data on safety and potential efficacy of Magnetic Resonance guided Focused Ultrasound Surgery (MRgFUS) in the treatment of pain caused by trapeziometacarpal osteoarthritis…
- Conditions
- Osteoarthritis, Hip Osteoarthritis, Hand Osteoarthritis
- Trial name
- NCT03467165
- Testing
- MRgFUS treatment
- Where
- Italy
- Volunteers
- 14 people
- Sponsor
- Istituto Ortopedico Rizzoli
Inflammatory Bowel Diseases
Multi-center Clinical Study of Cord Blood Stem Cell Transplantation for IBD Caused by IL-10R Gene Deficiency
Very early onset inflammatory bowel disease (VEO-IBD) is a special subtype of children's inflammatory bowel disease (IBD). VEO-IBD is mostly caused by single-gene defects and can be cured by allo-hematopoietic stem cell…
- Trial name
- NCT04170192
- Testing
- Cord Blood Stem Cell Transplantation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Children's Hospital of Fudan University
Neuropathic Pain, Neuroma
Neuromas as the Cause of Pain
Neuromas are frequent after trauma and surgery, including amputation and can be identified by high-resolution ultrasound. The role of neuromas as the cause of neuropathic pain is uncertain.
- Trial name
- NCT02930551
- Testing
- Lidocaine, Isotonic Saline
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Danish Pain Research Center
Jugular Vein Anomaly (Disorder), Diagnostic Self Evaluation
Evaluation Criteria, Diagnostic Criteria, Surgical Indications, and Establishment of Surgical Standards for "Cerebral Tinnitus Syndrome" Caused by Internal Jugular Vein Stenosis.
"Cerebral Tinnitus," also known as "cranial tinnitus," refers to the patient-reported perception of intracranial sounds. It often presents as "Cerebral Tinnitus Syndrome," which includes symptoms such as tinnitus with hearing…
- Conditions
- Jugular Vein Anomaly (Disorder), Diagnostic Self Evaluation, Nerosurgery, Assessment, Self
- Trial name
- NCT07560280
- Testing
- Atlas Transverse Process Mastoidectomy with Lysis and Perfusion
- Where
- China
- Volunteers
- 369 people, healthy volunteers welcome
- Sponsor
- Beijing Shijitan Hospital, Capital Medical University
Ureteropelvic Junction Obstruction
Functional Outcome After Minimally Invasive Pyeloplasty for Adult Patients With UPJO
an intervention study on adult patients with uretero-pelvic junction obstruction (UPJO) due to crossing vessels would be managed either through classic dismembered pyeloplasty or vascular hitch.
- Trial name
- NCT05895422
- Testing
- pyeloplasty
- Where
- Egypt
- Volunteers
- 17 people
- Sponsor
- Cairo University
Type 2 Diabetes, Vascular Diseases
Phenotyping Individuals With Neo-diagnosed Type 2 Diabetes at Risk for All-cause Mortality
Prevalence of type 2 diabetes (T2D) is increasing worldwide over the last two decades; in these patients the rate of all-cause and cardiovascular (CV) mortality is several folds higher than in the general population, configuring…
- Conditions
- Type 2 Diabetes, Vascular Diseases, Cardiac Disease
- Trial name
- NCT04453605
- Testing
- standard treatments
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University of Pisa
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