Clinical trials: Excision Margin
Customized Healing Abutment Bone Grafts Connective Tissue Graft Immediate Implant Placement
Midfacial Gingival Margin Changes Following Immediate Implants.
Dimensional changes, including the loss of labial soft tissues and midfacial gingival recession, seem to be inevitable following immediate placement.
- Trial name
- NCT05975515
- Testing
- Connective tissue graft /Bone graft/ Customized HA
- Where
- Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cairo University
Removal of Fibrosynovial Tissue, Non-removal of Fibrosynovial Tissue
Incidence of Patellar Crepitus in Removal and Non-removal of Fibrosynovial Tissue at Superior Pole of Patella
The purpose of this study is to compare the incidence of patellar crepitus complication and the clinical outcome between remove and not remove fibrosynovial tissue at the border of the superior pole of the patellar in posterior…
- Conditions
- Removal of Fibrosynovial Tissue, Non-removal of Fibrosynovial Tissue, Patellar Non-resurfacing
- Trial name
- NCT04429997
- Testing
- Removal of fibrosynovial tissue, Non-removal of fibrosynovial tissue
- Where
- Thailand
- Volunteers
- 138 people
- Sponsor
- Navamindradhiraj University
Pancreatic Cancer
Impact of Margin-accentuation IRE in Pancreatic Cancer
Pancreatic cancer is the fourth leading cause of cancer deaths overall and second after colon and rectum cancer among gastrointestinal cancers in Western countries.
- Trial name
- IRE Marg (NCT02952859)
- Testing
- Irreversible electroporation
- Where
- Switzerland
- Volunteers
- 26 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Blepharoptosis, Age-Related Macular Degeneration
Blepharoptosis After Repeated Intravitreal Anti-VEGF Injections: A Prospective Study
Intravitreal anti-VEGF injections are a mainstay of treatment for retinal diseases such as neovascular age-related macular degeneration, diabetic macular edema and retinal vein occlusion, and usually require repeated…
- Conditions
- Blepharoptosis, Age-Related Macular Degeneration, Diabetic Macular Edema
- Trial name
- NCT07821450
- Testing
- Repeated intravitreal anti-VEGF injection with eyelid speculum
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Abdulkadir Küçük
Rectal Cancer
Preoperative Prediction Model of Pathological Outcomes (Mesorectum Quality and Positive Circumferential Resection Margin) in Patients With Mid-low Rectal Cancer
Elaboration of a preoperative prediction model of the quality of the mesorectum and the involvement of the circumferential margin in patients with mid-low rectal cancer who undergo laparoscopic anterior rectal resection.
- Trial name
- PREMARE (NCT03107650)
- Testing
- Transanal total mesorectal excision of rectal cancer
- Where
- Spain
- Volunteers
- 323 people
- Sponsor
- Pere Planellas Giné
Adenocarcinoma of the Esophagogastric Junction
Intraoperative Margin Techniques for Esophagogastric Junction Adenocarcinoma: A Controlled Study
The goal of this clinical trial is to learn if the EndoScell Scanner (ES) imaging system can accurately assess tumor-free surgical margins during surgery for adenocarcinoma of the esophagogastric junction (AEG), compared with…
- Trial name
- NCT07095699
- Testing
- EndoSCell System
- Volunteers
- 314 people
- Sponsor
- Fudan University
Crohn's Disease, Recurrence
Crohn's Extent of Resection Trial
The trial will investigate if removing an additional length of small bowel will result in lower risk of recurrence at the surgical join (anastomosis), thereby decreasing the need for further surgery in the future.
- Trial name
- CERT (NCT01876264)
- Testing
- Extended resection, Conventional resection
- Where
- United Kingdom
- Sponsor
- Oxford University Hospitals NHS Trust
Brain Tumors With Ill-defined Margins
Intra-operative Use of Indigo Carmine Dye for the Delineation of Ill Defined Tumor Borders Using Stereotactic Injection
The purpose of this study is to investigate whether stereotactic indigo carmine injection can safely increase the extent of tumor resection.
- Trial name
- NCT01767415
- Testing
- Indigo carmine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Weill Medical College of Cornell University
Adenocarcinoma of the Pancreas
SBRT for Close or Positive Margins After Resection of Pancreatic Adenocarcinoma
The current study seeks to further investigate the impact of Stereotactic Body Radiation Therapy following pancreatic resection with a close or positive margin.
- Trial name
- NCT01357525
- Testing
- Stereotactic Body Radiation Therapy (SBRT)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- David A. Clump, MD, PhD
Dental Plaque
Train New Examiners Via Modified Gingival Margin Plaque
The purpose of this study is to train new examiners while testing two commercial products using our standard one-day brushing study regimen by measuring gingival margin plaque index.
- Trial name
- NCT00758563
- Testing
- Fluoride, Triclosan/Fluoride
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Bladder Cancer Stage I
Can Second Resection for pT1 Bladder Cancer be Avoided After Initial En-Bloc Resection With Negative Safety Margins
The goal of this [ Can second resection for pT1 bladder carcinoma be safely avoided after initial En-Bloc Resection with negative vertical and horizontal safety margins ? is to assess the impact of avoiding re TUR on Recurrence…
- Trial name
- NCT05969964
- Testing
- Avoid second resection after initial complete resection
- Where
- Egypt
- Volunteers
- 370 people
- Sponsor
- Mansoura University
Breast Neoplasm Female, Breast Cancer
Fluorescence Imaging of Carcinoma During Breast Conserving Surgery
Breast conserving surgery (BCS) is performed on patients with breast cancer to resect and completely remove the cancer while conserving as much of the surrounding healthy tissue as possible.
- Trial name
- NCT04815083
- Testing
- Aminolevulinic Acid Hydrochloride, Eagle V1.2 Imaging System
- Where
- 7 sites in United States
- Volunteers
- 57 people
- Sponsor
- SBI ALApharma Canada, Inc.
Colo-rectal Cancer
Safety & Efficacy of a Novel Asymmetrical Linear Stapler (NALS) for Securing Distal Resection Margin in Laparoscopic Rectal Cancer Surgery: Pilot Study
Through the use of a novel asymmetrical linear stapler (NALS, Meditulip co. Ltd.), we aim to prove that true distal margins greater than 1cm may be harvested more readily and easily compared to the conventional staplers.
- Trial name
- NCT06709170
- Testing
- Novel asymmetrical linear stapler, Signia™
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Transverse Colon Cancer
Resection Margin of Transverse Colon Cancer With Extracorporeal Versus Intracorporeal Anastomosis
The approach of anastomosis in laparoscopic resection of transverse colon cancer (TCC) has rarely been discussed. This study aims to compare the resection margin of TCC with extracorporeal anastomosis (ECA) versus intracorporeal…
- Trial name
- NCT05061199
- Testing
- approach of anastomosis
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Shanghai Minimally Invasive Surgery Center
Healthy Volunteers, Dynamic Stability Margin
Normative Dynamic & Magnetic Spine
This study aims to describe normal spinal musculoskeletal patterns in healthy adolescents and young adults by using static and dynamic measures.
- Conditions
- Healthy Volunteers, Dynamic Stability Margin, Gait, Paraspinal Muscles
- Trial name
- NDMS (NCT03125434)
- Testing
- EOS full-spine, MRI, gait analysis
- Where
- France
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Breast Neoplasms
The Breast Surgery EnLight and LightPath Imaging System Study
This study will correlate the resection margin status of the breast cancer tumour (WLE specimen), cavity shavings (if any) and breast cavity, and the metastatic status of axillary lymph nodes as determined by EnLight, LightPath…
- Trial name
- NCT02151071
- Testing
- EnLight, LightPath
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Lightpoint Medical Limited
Oropharyngeal Cancer
TraceIT Tissue Marker to Mark the Primary Resection Bed Margins of Oropharyngeal Cancers
The purpose of this research study is to look at how using an injectable marker called TraceIT can help with the radiation treatment planning process.
- Trial name
- NCT03713021
- Testing
- TraceIT Tissue Marker
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Washington University School of Medicine
Gastric Cancer
Extended Resection After Positive Intraoperative Pathology in Gastric Cancer Surgery
Of 737 consecutive patients undergoing (sub)total gastrectomy for gastric or GEJ adenocarcinoma, 679 cases with curative intent surgery between 05/1996 and 03/2019 were included.
- Trial name
- NCT05663450
- Volunteers
- 679 people
- Sponsor
- University Hospital of Cologne
Colon Cancer
The Value of MRI in Assessing the Status of Retroperitoneal Resection Margin in Colon Cancer
The goal of this clinical trial is to explore the value of colon MRI in assessing the status of retroperitoneal resection margin (RPRM) for advanced colon cancer.
- Trial name
- NCT05859581
- Testing
- Beyond complete mesocolic excision surgery
- Where
- China
- Volunteers
- 29 people
- Sponsor
- Peking University Cancer Hospital & Institute
Adenoma Colon Polyp
Evaluating Adenoma Recurrence After Endoscopic Mucosal Resection With Margin Marking or Post Treatment With Snare Tip Soft Coagulation
Non-inferiority trial comparing the recurrence rate of adenomas in non-pedunculated colonic lesions following endoscopic mucosal resection with margin marking (EMR-MM) and endoscopic mucosal resection with thermal margin ablation…
- Trial name
- ERADICATE (NCT06476145)
- Where
- United States
- Volunteers
- 342 people
- Sponsor
- AdventHealth