Clinical trials: Executive Function Disorders
Virtual Reality, Coordination Impairment
Effects of Immersive Virtual Reality Traning on an Eye-hand Coordination and Time Reaction
Virtual reality (VR) is a three-dimensional image, which is created by means of computer programs. In most educational communities VR has been used as an opportunity to support many students.
- Trial name
- NCT04662983
- Testing
- VR-training
- Where
- Poland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- The Opole University of Technology
Obesity
Genetic Influences Between Cognitive Function and BMI
In this study the investigators will interrogate an existing data set to examine whether genetic variants contribute to an inverse association between weight status and cognitive function.
- Trial name
- NCT03116334
- Where
- United States
- Volunteers
- 869 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Attention-deficit/Hyperactivity Disorder
Executive Functioning and Mindfulness in Adults With Attention Deficit/Hyperactivity Disorder Imaging
The main purpose of this study is to evaluate changes in brain functioning using an MRI machine following mindfulness meditation training.
- Trial name
- EFMImaging (NCT01629914)
- Testing
- Mindfulness Meditation
- Volunteers
- healthy volunteers welcome
- Sponsor
- Duke University
Autism Spectrum Disorder
rTMS for Executive Function Deficits in Autism Spectrum Disorder
In this study, the investigators will be examining the effects of repetitive transcranial magnetic stimulation (rTMS) on executive function deficits in individuals with autism spectrum disorder.
- Trial name
- NCT02311751
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Schizophrenia
Transcranial Direct Current Stimulation Influences on Cognitive Inhibition in Schizophrenia
A deficit in cognitive suppression is a trait of patients with schizophrenia. Cognitive suppression is the ability to control or suppress irrelevant responses and to adopt relevant responses instead.
- Trial name
- NCT01971073
- Testing
- transcranial direct current stimulation
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bar-Ilan University, Israel
Cognition, Affect (Mental Function)
ETASCAN Project: ETAS Project 2
This study aims to investigate the chronic effects of ETAS® on cognitive, affective and neural outcomes in healthy adults aged 60-80 years with mild to moderate subjective cognitive complaints.
- Conditions
- Cognition, Affect (Mental Function), Sleep, MRI
- Trial name
- ETASCAN (NCT07550140)
- Testing
- ETAS®
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Reading
Learning Disorders, Executive Dysfunction
Application of a Training Program for Executive Functions in a Sample of Egyptian Children With Learning Disorder
In recent years, significant progress has been made on ways to improve Executive Functions (EF) skills for school readiness involving direct EF training and classroom educational programs.
- Trial name
- NCT05476133
- Testing
- Executive functions training-elementary and Promoting executive function in in the classroom
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alexandria University
ADHD, Child, Only
A Randomized Controlled Study of MEFP for Preschool Children With ADHD
The goal of this study is to provide a new, early treatment approach for preschoolers with ADHD, which could facilitate the EF developing well to achieve better outcome.
- Trial name
- NCT03515135
- Testing
- Metacognitive Executive Function Training
- Where
- China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Weight Loss, Wait-List Control
Neurotrophic Indicators of Cognition, Executive Skills, Plasticity, and Adverse Childhood Experiences Study
Adverse childhood experiences (ACEs) are repeatedly shown to predict negative biopsychosocial health outcomes, including obesity.
- Trial name
- NICE SPACES (NCT04076722)
- Testing
- Stress reactivity stimuli
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University
Substance Dependence, Executive Function Disorder
Brain Mechanism and Intervention of Executive-control Dysfunction Among Substance Dependents
The investigators assume that tACS could improve amphetamine and alcohol dependent patients' executive-control function by adjusting the synchronization patterns and enhancing the functional connectivity of the prefrontal-ventral…
- Conditions
- Substance Dependence, Executive Function Disorder, Transcranial Alternating Current Stimulation
- Trial name
- NCT05312359
- Testing
- Transcranial alternating current stimulation-true stimulus
- Where
- China
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Attention Deficit Hyperactivity Disorder
Disturbed Structural Connectivity of Frontostriatal and Frontoparietal Networks in Adults With ADHD
Attention deficit/hyperactivity disorder (ADHD) is a common, impairing, childhood onset neuropsychiatric disorder with executive dysfunctions. The ADHD symptoms and executive deficits may last to adulthood.
- Trial name
- NCT02232464
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cognitive Impairment, Executive Dysfunction
Vascular Mechanisms for the Effects of Loss of Ovarian Hormone Function on Cognition in Women
Complaints about memory and thinking are common in women as they go through menopause and estrogen levels fall. The ovarian hormone estrogen is important for supporting normal cognitive function, and changes in brain activity and…
- Conditions
- Cognitive Impairment, Executive Dysfunction, Endothelial Dysfunction, Cardiovascular Disease
- Trial name
- NCT02122198
- Testing
- Leuprolide acetate, Estradiol, Medroxyprogesterone
- Where
- 2 sites in United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Parkinson's Disease
Galantamine Executive Function in Parkinson's Disease
The aim of the study is to determine whether galantamine stabilizes or improves thinking abilities in individuals with Parkinson's disease.
- Trial name
- NCT00211588
- Testing
- galantamine
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Memorial Hospital of Rhode Island
Alzheimer's Disease, Vascular Neurocognitive Disorder
Validation Study of the ExéSem Battery Designed to Differentiate the Contribution of Executive Functions in Semantic Disorders
This protocol describes a study aimed at evaluating the psychometric properties of the ExéSem battery, developed to differentiate semantic deficits from executive semantic impairments in patients with post-lesional or…
- Conditions
- Alzheimer's Disease, Vascular Neurocognitive Disorder, Progressive Primary Aphasia Semantic Variant, People Without Neurocognitive Disorder
- Trial name
- ExéSemVal (NCT07573046)
- Testing
- ExéSem cognitive battery
- Where
- France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Cognitive Change
Executive Function Training for Children and Adolescents
The goal of this clinical trial is to evaluate how different approaches to executive function (like adding game-like features, varying the number of tasks, and providing coaching) can enhance executive function outcomes in…
- Trial name
- NCT07147894
- Testing
- Nongamified N-back training, Gamified N-back training, Multiple Domain Training
- Where
- United States
- Volunteers
- 780 people, healthy volunteers welcome
- Sponsor
- Northeastern University
Alzheimer's Disease
Pathological and Non-pathological Aging, Physical Activity, Genotype and Cognition
Alzheimer's disease (AD) is an irreversible, progressive brain disease. It is the most common form of dementia and the major cause of functional dependence in the elderly.
- Trial name
- VIAGECO (NCT02520232)
- Testing
- Combination of aerobic and strength exercises, Stretching and balance exercise program
- Where
- 2 sites in France
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Traumatic Brain Injury, Major Depressive Disorder
Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations
In the current study, the investigators aim to understand the role of transcranial direct current stimulation (tDCS) in improving executive function across neuropsychiatric populations known to have deficits in this cognitive…
- Conditions
- Traumatic Brain Injury, Major Depressive Disorder, Bipolar Disorder, Schizophrenia
- Trial name
- NCT04296604
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Neurodevelopmental Disorders, Child Behavior
Neurodevelopmental Outcome After Prenatal Anesthesia
In 2016, the US Food and Drug Administration raised concerns about the potential negative effects of anesthesia exposure on neurodevelopment in children during pregnancy or before the age of three.
- Trial name
- NCT06052878
- Testing
- Parental telephone interview with standardized parental questionnaire from the "Behaviour Rating Inventory of Executive Function" (BRIEF), Parental questionnaire about their child's cognitive functioning in their daily life and medical history.
- Where
- France
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Stress Prevention, Cortisol
Pet Partners for Promotion of Academic Life Skills
The current study utilized a randomized controlled trial, conducted in a real-life setting, to determine whether, how, under which conditions, and for whom, infusing various levels of human-animal interaction (HAI) in a 4-week…
- Conditions
- Stress Prevention, Cortisol, Anxiety Disorders and Symptoms, Depression Disorders and Symptoms
- Trial name
- Pet PALS (NCT03530943)
- Testing
- Animal Assisted Activities, Academic Stress Management tools
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Washington State University
Spinal Cord Injury
Body Temperature in Persons With Tetraplegia When Exposed to Heat
The deleterious effects of hyperthermia are well appreciated in able-bodied persons. However, the consequences of impaired regulation of normal body temperature on cognitive performance of persons with tetraplegia is not known.
- Trial name
- NCT01890915
- Testing
- Heat Exposure
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center