Clinical trials: Executive Function Disorders
Schizophrenia, Schizoaffective Disorder
Targeting Cerebellum to Treat Psychosis: a Transcranial Magnetic Stimulation (TMS) Study
The goal of this study is to use transcranial magnetic stimulation (TMS) to investigate the impact of modulating cerebellar activity on time perception, executive function, and mood and psychotic symptoms in psychosis patients…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder I
- Trial name
- NCT02642029
- Testing
- Excitatory TMS, Inhibitory TMS
- Where
- 2 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Cognitive Impairment, Mild
Board Games Among Mild Cognitive Impairment Patients Experience (GAME Project)
Nowadays, on geriatric centres, cognitive decline used to be prevented by pen and paper exercises (Calero García \& Navarro Gonzalez, 2006). However, as Lampit et al.
- Trial name
- GAME-Project (NCT04835909)
- Testing
- Modern board and card games group, Paper and pencil tasks group
- Where
- 2 sites in Spain
- Volunteers
- 112 people
- Sponsor
- Brain In Game scientific-technical service
Delirium, Impaired Cognition
Simultaneous Recumbent Cycling and Cognitive Training
Intensive care units (ICU) provide life-saving care for nearly five million people annually. Up to 80% of patients receiving care in an ICU experience at least one episode of delirium.
- Trial name
- NCT04556227
- Testing
- Simultaneous Cycle/Cognitive Training
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Missouri, Kansas City
Executive Dysfunction, Cognitive Deficits
Cognitive Rehabilitation in Patients With Spina Bifida
This study will examine the effects of a theoretically grounded and manualized cognitive rehabilitation program on patients with Spina Bifida (SB).
- Conditions
- Executive Dysfunction, Cognitive Deficits, Spina Bifida
- Trial name
- NCT01302314
- Testing
- Goal management training (GMT)
- Where
- Norway
- Volunteers
- 38 people
- Sponsor
- Jan Stubberud
Neurologic Disorders, Schizophrenia
Characterization of High-Level Cognitive Impairments in Patients With Neuropsychiatric Disorders
Neuropsychiatric disorders are extremely common, severe, and disabling conditions. In the field of psychiatry, they notably include schizophrenia, mood disorders (depressive and bipolar disorders), autism spectrum or…
- Conditions
- Neurologic Disorders, Schizophrenia, Bipolar Disorder (BD), Depressive Disorder
- Trial name
- COGPSY (NCT07295652)
- Testing
- Cognitive assessment, Brain MRI (optional), Electroencephalography (optional)
- Where
- 3 sites in France
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Anomia, Post-stroke Aphasia
Executive Training and Anomia Therapy in Chronic Post-stroke Aphasia
Aphasia is a devastating acquired language impairment mainly caused by stroke, in which anomia is a quintessential clinical feature.
- Trial name
- ETAT PSA (NCT05101408)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Montpellier
Dyslexia, Executive Dysfunction
The Effects of Play and Competition-Based Cognitive Therapy
Purpose: The aim of this study was to investigate the effects of play and competition-based cognitive therapy (PCB-CT) on executive function and occupational routines in children with dyslexia.
- Trial name
- NCT03906097
- Testing
- Play and Competition-Based Cognitive Therapy
- Volunteers
- 64 people
- Sponsor
- Hacettepe University
COVID-19, Sars-CoV-2 Infection
Cognitive, Emotional and Behavioural Impairments in Patients After Sars-Cov2 Infection
Recent studies suggest cognitive, emotional and behavioural impairments occur in patients after SARS-CoV-2 infection. Problems with memory, attention, information processing and executive functions are particularly prevalent in…
- Trial name
- NCT05143320
- Where
- Italy
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Ospedale Generale Di Zona Moriggia-Pelascini
Traumatic Brain Injury
To Compare the Effect of Receiving the Technology-based Training Along With the Conventional Therapy to the Conventional Therapy Alone on Executive Functions Among People With Traumatic Brain Injury With Mild to Moderate Cognitive Deficit
The goal of this clinical trial is to compare the effect of receiving the technology-based training along with the conventional therapy to the conventional therapy alone on executive functions among people with traumatic brain…
- Trial name
- NCT06080269
- Testing
- technology based intervention along with conventional therapy, conventional therapy alone
- Where
- Qatar
- Volunteers
- 60 people
- Sponsor
- Hamad Medical Corporation
Mild Cognitive Impairment
Making Memory Better for Seniors With Mild Cognitive Impairment
The purpose of this study is to investigate the feasibility and effectiveness of a cognitive training group in individuals with Mild Cognitive Impairment, using a new paradigm that will optimize ecological validity by (1)…
- Trial name
- NCT01532739
- Testing
- Cognitive training
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Nova Scotia Health Authority
Attention Deficit Hyperactivity Disorder (ADHD), ADHD
Effects of Phosphatidylserine and DHA on Cognitive Performance in Children With ADHD
This study aimed to evaluate the effects of different phosphatidylserine (PS) formulations, with or without docosahexaenoic acid (DHA), on cognitive performance in children diagnosed with attention-deficit/hyperactivity disorder…
- Trial name
- PS-DHA-ADHD (NCT07521449)
- Testing
- Phosphatidylserine-Omega3, DHA Omega-3
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Çağlar Charles Daniel Jaicks
Alcohol Use Disorder
Social Cognition and Executive Functions in Alcohol Use Disorders - Transverse Study
Over the past few years, researchers and clinicians have stressed the major role of executive and social cognition impairments in the development and the maintenance of Alcohol Use Disorders (AUD).
- Trial name
- COSEFEX-T (NCT04647422)
- Testing
- Analysis of executive functioning and of social cognition processes
- Where
- France
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Autism, Autism Spectrum Disorder
Improving Academic and Social Functioning in Middle-Schoolers With Autism
The goal of this study is to test how well two group interventions work for middle-school children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT06705907
- Testing
- Achieving Independence and Mastery in School (AIMS), Building Essential Social Skills for Teens (BESST)
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Childhood Cancer, Cancer-related Problem/Condition
Effect of Cognitively Challenging Physical Activity on Executive Functions in Pediatric Cancer Patients
When it comes to exercise and sport for children and adolescents with cancer, there is often still the opinion that physical activity has a negative effect on the weakened body suffering from cancer.
- Conditions
- Childhood Cancer, Cancer-related Problem/Condition, Cognitive Side Effects of Cancer Therapy, Physical Activity
- Trial name
- KiKli Fit (NCT06839794)
- Testing
- Cognitively challenging physical activity for paediatric cancer patients, Physical activity recommendations
- Where
- Switzerland
- Volunteers
- 70 people
- Sponsor
- University of Bern
Primary Brain Tumor, Neurocognition
Executive and Socio-cognitive Functions in Survivors of Primary Brain Tumor: Impact on Patients' Quality of Life
Significant advances in primary malignant brain tumors (PBT) treatment have led to dramatically improved survival, both in children and adults.
- Conditions
- Primary Brain Tumor, Neurocognition, Quality of Life
- Trial name
- NEUROCOG-QOL (NCT02693405)
- Testing
- Executive functions, social cognition, quality of life
- Where
- France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
School Readiness, Developmental Delays
Early Intervention Foster Care: A Prevention Trial
The Early Intervention Foster Care [EIFC] project is an efficacy trial of the Oregon Social Learning Center Multidimensional Treatment Foster Care Program, a preventive intervention that targets 3 commonly co-occurring variables…
- Trial name
- EIFC (NCT00701194)
- Testing
- Early Intervention Foster Care (EIFC)
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- Oregon Social Learning Center
Cognitive Impairments, RRSO
LDX for the Treatment of Cognitive Functioning Issues in Women Post-Oophorectomy
This is a double-blind, placebo-controlled, study testing whether LDX improves cognitive function and EF in 20 postmenopausal women who report onset of cognitive difficulties after oophorectomy (with or without subsequent…
- Trial name
- LDX (NCT01986777)
- Testing
- lisdexamfetamine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Overweight and Obesity
Train Your Brain - Executive Function
The purpose of this research is to test if playing games designed to improve an individual's executive function can change their views about the types of foods they eat.
- Trial name
- NCT05938894
- Testing
- online games with various food images, online games with images of flowers and songbirds
- Where
- United States
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Healthy Volunteer
Effects of Interrupting Sedentary Behavior on Metabolic and Cognitive Outcomes in Children
Background: Some studies in adults have found that insulin and glucose blood levels are lower when a long period of sitting is broken up with walking, compared to sitting without breaks.
- Trial name
- NCT01888939
- Testing
- Walking on a Treadmill, Sedendary Activities Only
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cognition, Mood
Genistein, Equol, Cognitive Function and Mood: Twelve-week. (GECFAMc)
Isoflavones (ISF) are naturally occurring compounds that can provide protective benefits for certain domains of cognitive function.
- Trial name
- GECFAMc (NCT07742501)
- Testing
- Equol, Genistein, Maltodextrin
- Where
- United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Reading