Clinical trials: Executive Function Disorders
Preterm
Preschool Outcomes of a Previous RCT - ReDiMOM (NCT04540575)
This study will evaluate neurodevelopmental, health, and economic outcomes in preschool children born very preterm that participated in a randomized trial of an economic intervention designed to increase breastmilk feedings while…
- Trial name
- NCT07702357
- Testing
- This is a an observational prospective cohort study of a previous interventional trial (NCT04540575)
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- Rush University Medical Center
Autism Spectrum Disorder
Occupational Therapy Intervention in Children Diagnosed With Early and Late Autism Spectrum Disorder
Occupational Therapy Intervention in Children Diagnosed with Early and Late Autism Spectrum Disorder
- Trial name
- NCT07740863
- Testing
- Occupational Therapy Intervention
- Volunteers
- 30 people
- Sponsor
- SEDANUR GÜRLEK
Parkinson Disease
Neocortical Microarchitecture of Executive Function
This study is being done to the determine the ability and utility of using the Neuropixels probes in the human brain. A Neuropixels probe will be inserted into and removed from the brain of awake human patients who are undergoing…
- Trial name
- NCT06778135
- Testing
- Temporary implatation of large-scale intracranial electrode., brain electrode
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Colorado, Denver
Cognitive Impairment, Estrogen Deficiency
Effects of Ovarian Hormone Suppression on Vascular and Cognitive Function
Complaints about memory and thinking are common in women as they go through menopause. The female hormone estrogen is important for both the health of both the brain and the blood vessels.
- Conditions
- Cognitive Impairment, Estrogen Deficiency, Menopause, Endothelial Dysfunction
- Trial name
- NCT03112226
- Testing
- GnRHant + E2
- Where
- 2 sites in United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
ADHD
Metacognitive ADHD Telehealth Intervention for Work-performance Enhancement (Work-MATE)
Adults with Attention-deficit hyperactivity disorder (ADHD) experience poor occupational performance at work compare to adults without ADHD, manifested at tendencies toward unemployment, job instability, work accidents, and…
- Trial name
- NCT05270226
- Testing
- The Metacognitive ADHD Telehealth intervention for Work-performance Enhancement (Work-MATE)
- Where
- Israel
- Volunteers
- 46 people
- Sponsor
- Sara Rosenblum
Mild Cognitive Impairment
BestBrain Evaluation of Cognitive Memory & Executive-Function
This study is intended 1. To quantify the effects of the iRemember personalized EEG-NFB therapy on working memory and executive functions in subjects with MCI by calculating the percentage of change in the Neurotrax tests…
- Trial name
- BECOME (NCT03954340)
- Testing
- iRemember Neurofeedback (NFB)
- Where
- Israel
- Volunteers
- 140 people
- Sponsor
- BestBrain Ltd.
HIV, Aging
The Targeted Neurocognitive Training (TNT) Study
People with HIV (PWH) often suffer from cognitive impairments known as HIV-Associated Neurocognitive Disorder (HAND). Cognitive impairments in PWH are not fully captured by traditional neurocognitive assessment; thus, we must…
- Conditions
- HIV, Aging, Cognitive Function Abnormal, Cognitive Training
- Trial name
- TNT (NCT05773430)
- Testing
- Targeted Neurocognitive Training
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Bipolar Disorder
The Effect of Intranasal Insulin on Neurocognitive Function in Euthymic Patients With Bipolar Disorder
It is hypothesized that the intranasal administration of insulin will enhance hippocampal-dependent neurocognitive performance in euthymic patients with bipolar I or II disorder.
- Trial name
- NCT00314314
- Testing
- Intranasal Insulin, Diluent
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University Health Network, Toronto
Mild Cognitive Impairment, Walking
Impact of a Multicomponent Exercise Program on Cognitive and Functional Outcomes in Patients With Mild Cognitive Impairment
The goal of this randomised clinical trial is to investigate the effectiveness of an innovative therapeutic exercise program emphasizing in dual-task exercises in people with amnestic Mild Cognitive Impairment.
- Conditions
- Mild Cognitive Impairment, Walking, Balance, Cognition
- Trial name
- MExeProMCI (NCT07334392)
- Testing
- Innovative therapeutic exercise program, Therapeutic exercise program, Flyer
- Where
- Greece
- Volunteers
- 45 people
- Sponsor
- University of Patras
Insulin Growth Factor I Deficiency, IGF1 Deficiency
Effect of a HIIT Program on Quality of Life, Executive Functions, and IGF-1 Response in Sedentary Young University Women
Sedentary lifestyle, understood as an activity that requires minimal body movement (Tremblay et al., 2017), is one of the main factors responsible for chronic diseases in Young adults.
- Conditions
- Insulin Growth Factor I Deficiency, IGF1 Deficiency, Executive Function Disorder
- Trial name
- NCT05642169
- Testing
- HIIT, HIIT+PA, CON
- Where
- Spain
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Seville
Multiple Sclerosis
Combined Effects of Balance and Cognitive Training in Patients With Multiple Sclerosis
Multiple sclerosis is a potentially disabling disease of the brain and spinal cord involving the central nervous system. Multiple Sclerosis can cause balance and cognitive impairment in patients, affecting overall quality of…
- Trial name
- NCT06845722
- Testing
- Balance training, Cognitive Rehabilitation:
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Congenital Heart Disease, Executive Dysfunction
Learning by Heart: The Effectiveness of an EF Training Program for Pre-schoolers With Critical CHD
Advances in prenatal and neonatal care have improved outcomes in children with critical congenital heart disease (CCHD). With the increase in survival, neurocognitive problems such as executive functioning (EF) impairments have…
- Conditions
- Congenital Heart Disease, Executive Dysfunction, Attention Disorder
- Trial name
- LbH (NCT06267430)
- Testing
- Kleuter Extra training program
- Where
- 3 sites in Netherlands
- Volunteers
- 103 people
- Sponsor
- Erasmus Medical Center
Phenylketonuria
A Phase 3 Substudy to Evaluate Executive Function in Adults With PKU Who Are Participating in the Phase 3 Study, 165-302
A Phase 3 substudy to evaluate executive function in adults with phenylketonuria who are participating in the phase 3 Study, 165-302. Approximately 100 subjects, aged ≥ 18 to ≤ 70 years old, with PKU will be enrolled.
- Trial name
- PRISM303 (NCT02468570)
- Testing
- Administration of CANTAB and Subject Global Assessment
- Where
- 4 sites in United States
- Volunteers
- 9 people
- Sponsor
- BioMarin Pharmaceutical
Attention Deficit Hyperactivity Disorder Symptoms
Development of a Mobile App for an Executive Functioning Intervention for Adolescents
This study develops an initial prototype of a mobile tool that will support clinician-directed behavioral/organizational skills treatment for adolescents with Attention Deficit Hyperactivity Disorder (ADHD) with input guided from…
- Trial name
- NCT04018794
- Testing
- Behavioral/organizational skills intervention augmented with digital health application
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, San Francisco
Iron-deficiency, Iron Deficiency Anemia
Iron Deficiency in Female State Fair Attendees
This study aims to examine iron deficiency symptoms and biochemical iron status based on hemoglobin, hematocrit, ferritin, and total iron binding capacity in menstruating females.
- Conditions
- Iron-deficiency, Iron Deficiency Anemia, Iron Deficiency (Without Anemia)
- Trial name
- NCT03228173
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Behavioral and Emotional Disorder With Onset in Childhood
Emotional Dysregulation and Other Psychopathological Dimensions in Clinical Preschoolers
The purpose of the study is to investigate the emotional-behavioral dysregulation and its possible correlation with the main demographic and psychopathological variables in a sample of preschool children with internalizing and…
- Trial name
- NCT07805668
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS Fondazione Stella Maris
Myasthenia Gravis
Cognitive Functioning in People With Myasthenia Graivs: Impact on Daily Life Activities, Work, Disability and Quality of Life
MYCOG primarily aims to estimate the prevalence of cognitive difficulties in patients with MG treated at Besta Institute. Secondary aims include: a) assess the degree to which cognitive difficulties are associated to work…
- Trial name
- MYCOG (NCT06718855)
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Autism Spectrum Disorder
Exercise Interventions for Children With Autism Spectrum Disorder
The purpose of this clinical trial is to find out whether exergame and aerobic exercise can improve sleep, movement skills, thinking abilities, and brain activity in children with autism spectrum disorder (ASD).
- Trial name
- NCT07789457
- Testing
- Exergaming, Aerobic exercise, Conventional physical therapy
- Where
- Taiwan
- Volunteers
- 105 people
- Sponsor
- National Taiwan University Hospital
Healthy Adult Participants
The Effects of Multiple Object Tracking And Mental Imagery On Tennis Performance
The goal of this clinical trial was to evaluate whether multiple object tracking and mental imagery training affect tennis performance, executive functions, anxiety, and psychophysiological variables in university students…
- Trial name
- MOT-MI (NCT07794228)
- Testing
- Multiple Object Tracking Training, Mental Imagery Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Halic University
Metastatic Brain Tumor, Cerebral Metastases
Impact of Cognitive Rehab and Physical Activity on Cognition in Patients With Metastatic Brain Tumors Undergoing RT
To determine the feasibility of processes and instruments with an overarching purpose to guide the design of a larger study. To determine the feasibility of individuals with metastatic brain tumor(s) to engage in physical…
- Trial name
- NCT03096431
- Testing
- Physical Activity, Cognitive rehabilitation
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Virginia Commonwealth University