Clinical trials: Executive Functions
Executive Function
Brain Games to Improve Executive Function in São Paulo, Brazil
A growing body of research has highlighted the critical importance of children's self-regulation and executive function skills for their school performance as well as for their later life outcomes.
- Trial name
- NCT03491488
- Testing
- Brain Games
- Where
- Brazil
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Executive Function (Cognition)
Examining Executive Functions in Medical Students Across Different Types of Study Breaks
This study aims to expand on previous findings and compare the effects of an active break (ten minutes of walking or upper body movement), a digital break (ten minutes of phone use), and no break on memory and attention in…
- Trial name
- NCT06710678
- Testing
- Physical Activity Study Break, Social Media Study Break
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- New York Institute of Technology
Cognitive Change, Metabolic Syndrome, Protection Against
Nutritional Intervention for Sustaining Health (NURISH) Trial
The goal of this clinical trial is to learn if increasing adherence to a Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet pattern improves brain and heart health relative to a healthy control diet in…
- Conditions
- Cognitive Change, Metabolic Syndrome, Protection Against, Diet, Healthy
- Trial name
- NCT06437860
- Testing
- MIND Diet, Control Diet
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Healthy, Cognitive Function 1, Social
Active Gains in Brain Using Exercise During Aging
AGUEDA (Active Gains in brain using Exercise During Aging) is a randomized controlled trial designed to examine the effects of a 24-week resistance exercise program on brain health in cognitively normal adults between 65-80 years…
- Trial name
- AGUEDA (NCT05186090)
- Testing
- 24-week resistance exercise program
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Sedentary Behavior, Light Intensity Physical Activity
The Effect of Different Ways of Sitting on Cognitive Performance and Muscle Activity
Academic educations concurs with a lot of sitting. Studies have shown that prolonged sitting not only has disruptive effects on physical health, but also influence mental health and cognition negatively.
- Trial name
- NCT04716582
- Testing
- Sitting interrupted by light physical activity, Sitting with cognitive task, uninterrupted sitting
- Where
- Netherlands
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Age Related Cognitive Decline, Alzheimer's Disease
n-3 PUFA for Vascular Cognitive Aging
Brain scans can help identify changes that appear to increase risk for cognitive decline and dementia. Some of these brain changes are thought to reflect actual damage to the small blood vessels that support normal brain…
- Conditions
- Age Related Cognitive Decline, Alzheimer's Disease, Vascular Dementia, Endothelial Dysfunction
- Trial name
- NCT01953705
- Testing
- Omega 3 PUFA
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Mental Health
Implications of Myelin in Executive Control in Adolescence and Early Adulthood
The Myelex study is a fundamental research study that aims to better understand how the brain functions and develops. The objective of this study is to better understand the role of myelin, a sheath that surrounds nerve fibers…
- Trial name
- MYELEX (NCT06868966)
- Where
- France
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Executive Function
Modulation of Cognitive Control Signals in Prefrontal Cortex by Rhythmic Transcranial Magnetic Stimulation
Purpose: In this study, the investigators will provide causal evidence for the role of alpha and theta oscillations in cognitive control.
- Trial name
- NCT03828734
- Testing
- Theta TMS, Alpha TMS, Arrhythmic TMS
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Executive Dysfunction, Occupational Problems
Investigation of the Relationship Between Executive Functions and Occupational Performance of Children With Duchenne Muscular Dystrophy
The effects of Duchenne muscular dystrophy and its treatments on executive functions and occupational performance are under-mentioned in the literature.
- Conditions
- Executive Dysfunction, Occupational Problems, Duchenne Muscular Dystrophy
- Trial name
- NCT06868784
- Testing
- Evaluations
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Lokman Hekim University
Healthy, Healthy Adult Participants
Muévete conCiencia: Exercise and Mind-Body Program for University Students
The goal of this clinical trial is to evaluate whether different physical exercise and mind-body interventions can improve executive functions and reduce stress in first-year university students.
- Trial name
- NCT07443904
- Testing
- Motor-Cognitive Dual-Task Exercise (DT), Tai Chi Mind-Body Exercise (TC), Cognitive Stimulation (CS)
- Where
- Chile
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Universidad San Sebastián
Preschool Child, Executive Function (Cognition)
Do Motor Synchrony Games Improve Self Regulation?
The goal of this study is to determine if progressively more challenging playground games (motor synchrony games) improve executive function in preschool-aged children.
- Trial name
- MSG (NCT06647693)
- Testing
- Motor Synchrony Games (MSG)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Executive Function
Causal Role of Frontostriatal Circuitry in Goal-directed Behavior
The purpose of this clinical trial is to investigate the causal role that frontostriatal circuitry plays in goal-directed behavior. The participants will perform a reward-based decision-making task.
- Trial name
- NANCY (NCT05593965)
- Testing
- Delta-beta TMS, Theta-gamma TMS, Arrhythmic TMS
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Executive Function, Motor Activity
Performance Enhancement and Non-Invasive Brain Stimulation
A promising form of enhancing brain function non-invasively involves stimulating the brain using weak magnetic or electric currents.
- Conditions
- Executive Function, Motor Activity, Brain Stimulation
- Trial name
- NCT02498574
- Testing
- Transcranial Direct Current Stimulation, Working Memory Training
- Where
- 2 sites in Canada
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Bruyère Health Research Institute.
Autism Spectrum Disorders, Mood Disorders
Multidimensional Measurement of Psychopharmacological Treatment Response
The study examines actigraphic, observational, psychometric and associated repeated measurements obtained prior to and during psychopharmacological treatment.
- Conditions
- Autism Spectrum Disorders, Mood Disorders, Sleep Disorders, Attention Deficit Disorders
- Trial name
- NCT01184235
- Testing
- Pharmacological Intervention
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Child Psychopharmacology Institute
Overweight, Obesity
Mini-trampoline Intervention vs. Nordic Walking: Balance, Fitness and Neuropsychological Effects
The effects of mini-trampoline training on balance, cardiorespiratory fitness, strength and neuropsychological parameters in an overweight or obese population are unknown.
- Trial name
- TraWaFit (NCT02596152)
- Testing
- mini-trampoline, Nordic Walking
- Where
- Switzerland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Arno Schmidt-Trucksäss
MCI, Subjective Cognitive Decline
Senior Driving Simulation Training for Subjective Cognitive Decline and Mild Cognitive Impairment
This study aims to establish the Senior Driving Simulation Training (SDST) for Subjective Cognitive Decline (SCD) and Mild Cognitive Impairment (MCI), and explore the effectiveness of Senior Driving Simulation Training (SDST) on…
- Conditions
- MCI, Subjective Cognitive Decline, Healthy Aging
- Trial name
- SDST (NCT05380284)
- Testing
- Senior Driving Simulation Training, Waiting list control
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Schizophrenia, Schizoaffective Disorder
Effect of Varenicline on Cognitive Function in Cigarette Smokers With Schizophrenia
Smokers with schizophrenia have more difficulties quitting smoking than smokers without a mental disorder. Varenicline (Champix) is a new stop smoking medication with a unique mechanism of action.
- Trial name
- NCT01093365
- Testing
- Varenicline
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Mood, Cognitive Performance
The Effects of A Proprietary Spearmint Extract on Cognitive Performance
This study was designed to evaluate the chronic effects of a proprietary spearmint extract over 90 days of supplementation on aspects of cognitive performance (cognitive function and active reaction time), subjective mood, and…
- Conditions
- Mood, Cognitive Performance, Sleep
- Trial name
- NCT02518165
- Testing
- Proprietary spearmint extract
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Kemin Foods LC
Multitasking Behavior and Neural Representations Associated With Multitasking Ability, Healthy Volunteers
Cognitive Control & the Functional Organization of the Frontal Cortex
The goal of this basic experimental clinical trial is to understand the effect of multitasking practice on the structure of neural representations of tasks in the human lateral prefrontal cortex and control brain regions.
- Conditions
- Multitasking Behavior and Neural Representations Associated With Multitasking Ability, Healthy Volunteers, Executive Function
- Trial name
- NCT06436209
- Testing
- Multitask Practice Intervention (MPI), Single-task Practice Intervention (SPI)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brown University
Attention, Cognitive Training
Xbox-Based Exergames Versus Structured Home-Based Cognitive Training for Attention and Executive Functions in Healthy Adults
Background: Exergames are increasingly used to support cognition in older adults; however, evidence comparing exergames with non-computerized cognitive training in healthy adults remains limited.
- Conditions
- Attention, Cognitive Training, Executive Functions (EF), Xbox-based Exergames
- Trial name
- NCT07809412
- Testing
- Xbox-based exergames intervention, Structured home-based cognitive training
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medipol University