Clinical trials: Exercise Adaptations
Healthy, Healthy Participants
Acute Effects of Structured Exercise and Static Stretching on Vascular Function, Neuromuscular Performance, and Metabolic Regulation in Adults
This experimental study investigates the acute cardiovascular and vascular responses to a single session of resistance training, with and without additional static stretching, compared with a resting control condition.
- Conditions
- Healthy, Healthy Participants, Healthy Subjects (HS), Resistance Training Adaptation
- Trial name
- NCT07364149
- Testing
- Resistance Training, Resistance training + Static Stretching
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Postural Control
Effects of an Adapted Physical Activity on the Postural Control of Residents in Nursing Home.
This study measures the effects of an Adapted Physical Activity on postural control of residents in nursing home. Half of participants will follow a program training 3 times a week during 8 weeks, while the other half will…
- Trial name
- NCT03759977
- Testing
- Adapted Physical Activity
- Where
- Switzerland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Exercise Training, Physical Activity
Histamine H1/H2 Receptors and Training Adaptations
Exercise training is beneficial for both health and performance. Histamine has been shown to be involved in the acute exercise response.
- Trial name
- NCT04450134
- Testing
- Lactose, Fexofenadine Hydrochloride, Famotidine
- Where
- Belgium
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University Ghent
Physical Activity
Does Dapagliflozin Augment The Favorable Adaptation To Endurance Exercise Training?
Exercise is frequently prescribed as a favorable lifestyle intervention to prevent/reverse type 2 diabetes. It is also prescribed in addition to concurrent pharmacological treatment, such as metformin.
- Trial name
- NCT02371187
- Testing
- Dapagliflozin
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Christopher Bell
Cardiovascular Diseases
Impact of Statin Therapy on Adaptations to Aerobic Exercise
The purpose of this study is to determine how different doses of a statin affect muscle health and exercise.
- Trial name
- NCT03360916
- Testing
- Lipitor 20Mg Tablet, Lipitor 80Mg Tablet, Exercise Program
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Physical Inactivity
State Mindfulness Scale for Physical Activity: Validity and Reliability
The American College of Sports Medicine (ACSM) states that physical activity is very important for healthy adults as it provides many health and psychological benefits.
- Trial name
- NCT05994222
- Testing
- Assessment Group
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Istinye University
Developmental Coordination Disorder
Effects of Acute Exercise on Motor Learning and Brain Activity in Children With DCD
The aim of this study is to investigate the impact of an acute intense physical exercise bout on the learning ability of children with typical motor development (TD) and children with developmental coordination disorder (DCD).
- Trial name
- ExLeBrainDCD (NCT05936372)
- Testing
- Acute intense aerobic exercise
- Where
- 3 sites in Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Institut Nacional d'Educacio Fisica de Catalunya
Core Muscle Weakness, Postural Control Deficit
"CORE Training for Musculoskeletal Health: A Study on Adaptive Exercise Protocols"
This study aims to evaluate the effects of an adaptive core training protocol that integrates core stability, core strength, and high-intensity core power exercises on muscle activation, hypertrophy, balance, and quality of life.
- Conditions
- Core Muscle Weakness, Postural Control Deficit, Trunk Stability Impairment, Functional Performance Limitation
- Trial name
- RCT-EMG-US-QoL (NCT07025395)
- Testing
- - Core Training Protocol, Control Group Core Routine
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ioannis Tsartsapakis
Exercise Training
Exercise-Induced Metabolic Compensation; a Physiological Adaptive Response to Exercise Training
The primary aim of this proposal is to identify changes in the volume of highly metabolic organs (liver, kidneys, and brain) that occur as a physiological adaptation to exercise training and lower the resting energy expenditure.
- Trial name
- NCT04460040
- Testing
- Exercise training
- Where
- Israel
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Schizophrenia, Physical Activity
A Controlled Study With Remote Web-based Adapted Physical Activity (e-APA) in Psychotic Disorders
In this study, an APA program by web (e-APA) will be offered to two groups of participants (21 patients and 21 healthy volunteers (HV)) in remote video (use of the SAPATIC (Santé Activités Physiques Adaptées utilisant les…
- Conditions
- Schizophrenia, Physical Activity, Schizo Affective Disorder
- Trial name
- PEPSYV@SI (NCT03261817)
- Testing
- Physical activity (APA), Health Education program (HE)
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Aging
Efficacy of Pre-sleep or Post-exercise Protein During 12 Weeks of Resistance Exercise Training
The goal of this clinical trial is to compare the effects of protein consumption before sleep or immediately after exercise during 12 weeks of resistance exercise training in older adults.
- Trial name
- NCT05922475
- Testing
- Protein
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Florida State University
Obesity & Overweight, Childhood Obesity
Combined Inspiratory Muscle Training and Functional High-Intensity Interval Training in Boys With Obesity
Childhood obesity is associated with reduced cardiorespiratory fitness, impaired exercise tolerance, and altered respiratory mechanics.
- Trial name
- IMT and HIIT (NCT07810361)
- Testing
- Inspiratory Muscle Training, Functional High-Intensity Interval Training
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Intermittent Claudication, Peripheral Arterial Disease
Effect of Exercise on Patients With Claudication Undergoing Surgery
Title: How does exercise improve the calf muscle in patients with poor blood supply to their leg? Purpose of the project: Patients with peripheral arterial disease have a poor blood supply to their lower leg.
- Trial name
- NCT01980602
- Testing
- Supervised Exercise program
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Hull
Healthy Children
Adapted Frenkle Exercises Versus Dynamic Balance Training in School Going Children
A randomized clinical trial will be conducted at Realm Educational School. Children aged 6-12 years will be randomly assigned to either the AFE or DBT group using convenient sampling.
- Trial name
- DBT (NCT07619807)
- Testing
- Adapted Frenkle Exercises, Dynamic Balance Training
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Pregnant Women
Adapted Physical Activity to Promote Quality of Life, Well-being and Physical Activity Levels in Pregnant Women (WELL-DONE!Study)
The aim of the WELL-DONE! Study is to co-design, using different professional figures (midwives, psychologists, master's degree in motor science) but also taking into consideration the pregnant women's point of view, an…
- Trial name
- WELL-DONE! (NCT04735146)
- Testing
- Adapted physical activity
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- First Cycle Degree in Midwifery in collaboration with the Department of Biomedical and Neuromotor Sc
Hypertension, Elevated Blood Pressure
Blood Pressure Following Isometric Exercise in Inactive Adults
This study investigates how isometric exercise training (IET) affects blood pressure in physically inactive adults. Isometric exercise involves sustained muscle contractions without movement-for example, pushing against a fixed…
- Conditions
- Hypertension, Elevated Blood Pressure, Sedentary Lifestlye
- Trial name
- BELIEF-BP (NCT06937164)
- Testing
- Isometric Exercise Training (IET), Expectation-Enhancing Informational Framing
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Canterbury Christ Church University
Obesity
Progressive Metabolic Adaptations to Low Intensity Exercise Training and Weight Loss
the investigators first aim is to determine the effect of low intensity exercise (without weight loss) on insulin sensitivity, muscle lipid metabolism, and factors regulating these processes in skeletal muscle after 1 day, 2 wks…
- Trial name
- NCT01452074
- Testing
- Exercise Training, Weight Loss with continued Exercise Training
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Neurodegenerative Diseases, Leukodystrophy
Home Exercise for Individuals With Neurodegenerative Disease
The primary goal of this study is to address the need for targeted therapeutic interventions for impairments that impact walking in related neurodegenerative diseases.
- Conditions
- Neurodegenerative Diseases, Leukodystrophy, Ataxia, LBSL
- Trial name
- NCT05443906
- Testing
- Home exercise
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Aging, Physical Activity
Heterogeneity of Vascular Adaptations to Exercise With Aging in Women and Men
The goal of the proposed study is to understand the reasons for the variability in aerobic exercise (AE) training benefits on the vasculature in middle-age and older (MA/O) adults, including differences between men and women.
- Conditions
- Aging, Physical Activity, Vascular Health
- Trial name
- ELEVATE (NCT06912984)
- Testing
- Aerobic Exercise Training
- Where
- United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Healthy
Cognitive Effects of Life Kinetik-Adapted Physical Activity Cards
The purpose of this study is to investigate the effects of physical activity cards integrated with Life Kinetik exercises on attention, short-term memory, cognitive flexibility, and problem-solving skills in middle school…
- Trial name
- NCT07335848
- Testing
- Life Kinetik Adapted Physical Activity Cards Training, Physical activity cards training
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Enes Sucular