Clinical trials: Exercise Capacity, open to volunteers
Post COVID-19 Syndrome, Functional Inspiratory Muscle Training
Effectiveness of Functional Respiratory Muscle Training in Post-COVID-19 Syndrome
This study aims to investigate the effects of core stabilization exercises and functional inspiratory muscle training (IMT) on various physiological and psychological parameters in individuals with post-COVID-19 syndrome.
- Conditions
- Post COVID-19 Syndrome, Functional Inspiratory Muscle Training, Core Stabilization
- Trial name
- NCT07051954
- Testing
- Core Stabilization, Functional Inspiratory Muscle Training (IMT)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hacettepe University
Chronic Obstructive Pulmonary Disease (COPD), Muscle Oxygenation
Analysis of Muscle Oxygen Saturation and Functional Variables During Physical Capacity Assessments in Patients With COPD
This experimental pre-post intervention study aims to evaluate the effect of a respiratory physiotherapy and combined strength and cardiovascular training program on muscle oxygen saturation and functional capacity in patients…
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Muscle Oxygenation, Exercise, Respiratory Physiotherapy
- Trial name
- NCT06968273
- Testing
- Combined respiratory physiotherapy and cardiovascular-strength training program
- Where
- Portugal
- Volunteers
- 15 people
- Sponsor
- University of Extremadura
Aging
Sedentary or Exercised : Neuromuscular and Immunometabolic Observations and Retrospection
The distinction between healthy and pathological ageing has given rise to the vitality capacity concept. Underlying the physiological aspect of ageing, vitality capacity is reflected in the neuromuscular function, metabolism, and…
- Trial name
- SENIOR (NCT06692543)
- Testing
- Active population, Inactive population
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
HFrEF - Heart Failure With Reduced Ejection Fraction
Impact of Barostimulation on Hemodynamics in Adults With Heart Failure
This study evaluates the effects of the implantation and adjustment of the CVRx Barostim device in adult patients with heart failure with reduced ejection fraction who are receiving maximally tolerated doses of guideline directed…
- Trial name
- BREATHE-HF (NCT07335510)
- Testing
- Baroreflex Activation Therapy
- Where
- 7 sites in United States
- Volunteers
- 58 people
- Sponsor
- Columbia University
Sleep Disturbance, Aging
Sleep Quality in Assisted-Living Residents
Assisted living residents who have sleep disturbances are at great risk of developing cognitive impairments. The identification of factors that increase sleep problems in this population is the first step towards improving sleep…
- Trial name
- NCT04400617
- Testing
- Cross-sectional assessments to examine the relationship among sleep quality, functional/physical capacity, and cognitive performance.
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- University of Calgary
Morbid Obesity, Bariatric Surgery
Exercise to Fight Obesity
This clinical trial aims to determinate whether a structured exercise program, supported by telerehabilitation, can help individuals with severe obesity who are going to undergo bariatric surgery.
- Conditions
- Morbid Obesity, Bariatric Surgery, Telerehabilitation
- Trial name
- ExFO (NCT06934681)
- Testing
- Usual Care Group, Controlled exercise with telerehabilitation
- Where
- 2 sites in Spain
- Volunteers
- 72 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Heart Failure
Low Intensity Physical Activity in Congestive Heart Failure Patients Among Different BMI
This study examined the effects of low-intensity physical activity on functional capacity, quality of life, and psychological well-being in congestive heart failure patients with varying BMI.
- Trial name
- NCT07062900
- Testing
- Low-Intensity Physical Activity, usual care
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Type 2 Diabetes Mellitus (T2DM)
Long-Term Benefits of Eccentric Cycling Exercise in Patients With Type 2 Diabetes Mellitus
The goal of this interventional study is to evaluate the long-term benefits of eccentric (ECC) cycling exercise on physiological responses, exercise capacity, and quality of life (QoL) in patients with type 2 diabetes mellitus…
- Trial name
- NCT07109102
- Testing
- Moderate-intensity eccentric cycling, High-intensity eccentric cycling, Moderate-intensity concentric cycling
- Where
- Malaysia
- Volunteers
- 30 people
- Sponsor
- Universiti Sains Malaysia
Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease
Assessment of Lung Function (Lufu) at Sea Level LA vs. High Altitude HA in Patients With Pulmonary Arterial Hypertension PAH
To study the effect of a re-ascent to high altitude (Quito Ecuador: 2850m) after a one-week stay at sea level (after prior descent from 2850m) on lung function and pulmonary resistance/reactance in patients with pulmonary…
- Conditions
- Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease, High Altitude Effects, High Altitude
- Trial name
- NCT07804576
- Testing
- Re-ascent from sea level to 2850m
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Silvia Ulrich Somaini
Pulmonary Arterial Hypertension
Spironolactone for Pulmonary Arterial Hypertension
Background: High blood pressure in the lungs, known as pulmonary arterial hypertension (PAH), is a rare disorder. In spite of recent advances in treatment, the death rate remains unacceptably high.
- Trial name
- NCT01712620
- Testing
- Spironolactone
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Healthy, Healthy Adult
Sleep-Assessment in Patients Between High Altitude HA vs. Sea Level LA in Healthy Individuals H
To study the effect of relocation from high altitude (Quito Ecuador: 2850m) to sea level on sleeping parameters by polygraphy in healthy individuals, who live permanently >2600m.
- Conditions
- Healthy, Healthy Adult, High Altitude Effects, High Altitude
- Trial name
- NCT07801950
- Testing
- Descent from 2850m to sea level and re-ascent back to 2850m
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Silvia Ulrich Somaini
Lower Limb Lymphedema, Unilateral Leg Edema
Effects of Hydrotherapy on Unilateral Lower Extremity Lymphedema
Lymphedema is a chronic condition that negatively affects patients' quality of life and lower extremity functions, causing swelling and a feeling of heaviness in the extremity, as well as posing an economic burden.
- Trial name
- NCT06839885
- Testing
- Interventional group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Heart Failure With Reduced Ejection Fraction, Heart Failure With Preserved Ejection Fraction
Exercise Capacity Improvement by Conduction System Pacing in heArt Failure patieNts Without Compelling CRT inDication
This randomized controlled trial aims to investigate the impact of conduction system pacing in comparison to right ventricular apical pacing on exercise capacity, as measured by peak oxygen uptake (VO2peak), in heart failure…
- Conditions
- Heart Failure With Reduced Ejection Fraction, Heart Failure With Preserved Ejection Fraction, Heart Conduction Disorder
- Trial name
- ESCPAND (NCT06278844)
- Testing
- Conduction system pacing, Right ventricular apical pacing
- Where
- Belgium
- Volunteers
- 75 people
- Sponsor
- University Hospital, Antwerp
Aging
Healthy Aging Through Optimized Exercise
here is enormous variation in how individuals respond to exercise and understanding the factors that drive this variation will guide individualized exercise prescriptions to improve or maintain health into older age.
- Trial name
- HELIOS (NCT07093216)
- Testing
- Exercise
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Healty Male Volunteers, Athlete
The Effect of Respiratory Muscle Warm-up on Pulmonary Diffusion Capacity in Athletes
Several studies suggest that inspiratory muscle warm-up (IMW) could potentially affect exercise performance; however, its mechanistic basis is still unclear.
- Trial name
- NCT06736236
- Testing
- Inspiratory muscle warm-up, General warm-up (Control)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Emre Karaduman
Interstitial Lung Diseases (ILD), Exercise Capacity
Validity and Reliability of 6-minute Pegboard and Ring Test in Patients With Interstitial Lung Disease
Interstitial lung diseases (ILD) are a heterogeneous group of chronic respiratory diseases that cause significant mortality and morbidity worldwide, characterized by diffuse inflammation in the lung parenchyma and vascular…
- Conditions
- Interstitial Lung Diseases (ILD), Exercise Capacity, Upper Extremity
- Trial name
- NCT06948916
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Gazi University
Myocardial Infarction (MI), Cardiac Rehabilitation
Eccentric Exercise Rehabilitation After Myocardial Infarction
This clinical trial will evaluate a two-week eccentric exercise program conducted as part of comprehensive cardiac rehabilitation in patients after a heart attack (myocardial infarction).
- Trial name
- ECCENTRIC-MI (NCT07729410)
- Testing
- Standard Inpatient Cardiac Rehabilitation, Eccentric Cycling Exercise
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Gdansk
Single-ventricle, Stenosis
Transcatheter Fontan Stenting: Impact on Hepatic Stiffness and Exercise Capacity
The goal of this observational study is to assess the clinical impact following Fontan stent placement for extracardiac Fontan conduit (EFC) stenosis in patients with single-ventricle Fontan-palliated patients ages 12-21 years…
- Trial name
- NCT07073612
- Testing
- Cardiopulmonary Exercise Testing (CPET), Shear Wave Elastography Scan
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's Hospital Los Angeles
Stroke, Post-stroke Depression
Physical Capacity Building for Chronic Stroke
Cardiac rehabilitation is the standard-of-care treatment option for patients with cardiovascular disease and has been shown to improve many aspects critical to patient recovery.
- Trial name
- NCT07039305
- Testing
- Physical capacity training for chronic stroke - building aerobic capacity and muscle strength
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Medical University of South Carolina
Lipedema
Validity and Reliability of the Turkish Duke Activity Status Index in Women With Lipedema
This study aims to evaluate the validity and reliability of the Turkish version of the Duke Activity Status Index (DASI) in women with lipedema.
- Trial name
- DASI-LIP (NCT07803913)
- Testing
- Duke Activity Status Index (DASI)
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Istanbul University - Cerrahpasa