Clinical trials: Exercise Induced Muscle Damage
Probiotics
The Effects of Probiotic Supplementation on Markers of Muscle Damage and Performance Following Exercise Induced Muscle Damage
To determine the effect of probiotic supplementation on the inflammatory response and subsequent performance following a muscle damaging exercise bout, a double-blind, randomized placebo controlled two-factor repeated measures…
- Trial name
- PRO001 (NCT02520583)
- Testing
- Lactic acid bacteria and bifidobacteria
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Texas Christian University
Muscle Damage, Muscle Soreness
The Effects of Restriction Pressure on Muscle Damage Responses to Blood Flow Restriction Exercise
Blood flow restriction (BFR) exercise involves the application of a constriction device to the limbs to restrict muscle blood flow during exercise.
- Conditions
- Muscle Damage, Muscle Soreness, Muscle Strength
- Trial name
- NCT05037942
- Testing
- Blood flow restriction at 40% limb occlusion pressure, Blood flow restriction at 80% limb occlusion pressure
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Healthy Volunteer
Evaluation of Astaxanthin Properties on Anti-fatigue
Ten young, healthy, physically active male college students were crossed over for AST or placebo supplements randomized into placebo or AST trials and orally consumed placebo or AST (28 mg/d) supplements for four days.
- Trial name
- NCT06593535
- Testing
- Astaxanthin (AST trial)
- Where
- Taiwan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Muscle Weakness, Muscle Damage
Acute Physiological Responses to Twice Daily Blood Flow Restriction Training
The Academic Department of Military Rehabilitation (ADMR) is currently conducting a pan-defence, randomised control trial (RCT) investigating the utility of twice daily blood flow restriction training in UK military personnel…
- Trial name
- NCT06334224
- Testing
- Low load resistance training with blood flow restriction, Low load resistance training
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Defence Medical Rehabilitation Centre, UK
Menstrual Cycle Phase
Menstrual Cycle and Exercise-induced Muscle Damage
The aim of the study is to investigate the effect of the different menstrual cycle phases on the recovery from exercise-induced muscle injury in eumenorrheic women.
- Trial name
- MC-EIMD (NCT07322874)
- Testing
- Exercise during follicular phase, Exercise during luteal phase
- Where
- Greece
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Chariklia K. Deli
Injury, Inflammation
Nutritional Supplement, Eccentric Exercise and Recovery
The objectives of this study are to assess the effectiveness of a nutritional supplement on muscle functional recovery following induced muscle damage from high intensity resistance exercise.
- Trial name
- NCT01444170
- Testing
- dicreatinol sulfate
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Florida
Muscular Injury
Turmeric and Exercise-Induced Muscle Damage and Oxinflammation
The purpose of this study is to measure the effect of using a turmeric-based supplement for 2-weeks on muscle damage and soreness that occur in the body after 90-minutes of exercise.
- Trial name
- NCT04765527
- Testing
- Turmeric Strength for Joint
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Exercise Induced Muscle Damage
The Effect of Curcumin Supplementation on Recovery From Exercise-induced Muscle Damage
Recent evidence suggests that curcumin supplementation may reduce muscle inflammation, oxidative markers, and muscle damage. The most favourable dosage to elicit these ergogenic effects are yet to be established; both 750mg \&…
- Trial name
- NCT05346211
- Testing
- Curcumin
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- St Mary's University College
Eccentric Hypertrophy, Muscle Damage
Comparing Two Eccentric Protocols on Muscle Damage
The purpose of this study will be to test whether a new way of weight training is more effective than typical weight training. The investigators expect that this new way will cause more exercise-induced muscle damage, which helps…
- Trial name
- NCT06992271
- Testing
- Fast Eccentric, Slow Eccentric
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- New York Institute of Technology
Aseptic Muscle Injury
Effects of Protein and NAC Co-ingestion on Skeletal Muscle Recovery
Previous evidence suggests that though N-acetylcysteine (NAC) supplementation following eccentric exercise-induced muscle damage disrupts the skeletal muscle's repair and remodelling process at 8 days of recovery, it attenuates…
- Trial name
- PRoNAC (NCT06367413)
- Testing
- NAC, NAC + Whey Protein
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Exercise Induced Muscle Damage
Indirect Biomarkers and Exercise Induced Muscle Damage
The purpose of this study is to investigate the magnitude of changes in biomarkers of exercise-induced muscle damage following an acute bout of eccentric exercise of the knee extensors performed on an isokinetic dynamometer.
- Trial name
- NCT07503860
- Testing
- Eccentric Exercise
- Where
- Greece
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Vassilis Paschalis
Recovery
Influence of Specific Collagen Peptides on Recovery After Exercise Induced Muscle Damage
The present study aims at investigating the potential influence of specific collagen peptides on recovery after exercise induced muscle damage with focus on long-term effects.
- Trial name
- NCT05220371
- Testing
- Collagen, Concurrent training
- Where
- Austria
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Cardiovascular Diseases, HMG COA Reductase Inhibitor Adverse Reaction
Exercise-induced Muscle Damage in Statin Users
Rationale: Combining statin treatment and physical activity is very effective for the prevention of cardiovascular diseases. Statins are well-tolerated by most patients, but may cause statin-associated muscle symptoms (SAMS) and…
- Conditions
- Cardiovascular Diseases, HMG COA Reductase Inhibitor Adverse Reaction, Muscle Damage
- Trial name
- NCT05011643
- Testing
- Moderate-intensity exercise
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Sarcopenia
Protein Intake and Exercise-induced Muscle Damage
The goal of this clinical trial is to test the effect of different protein-enhancement strategies versus carbohydrate control on exercise-induced muscle damage in physically active older adults.
- Trial name
- PROMO (NCT06235476)
- Testing
- whey protein supplement, mixed plant-based protein supplement, e-health application
- Where
- Netherlands
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Exercise-Induced Muscle Damage, Delayed Onset Muscle Soreness (DOMS)
Curcumin Versus Ibuprofen for Exercise-Induced Muscle Damage in Physically Active Women
xercise-induced muscle damage (EIMD) is a common consequence of unaccustomed or high-intensity exercise and is characterized by muscle soreness, impaired physical performance, inflammation, oxidative stress, and increased…
- Conditions
- Exercise-Induced Muscle Damage, Delayed Onset Muscle Soreness (DOMS), Sports Recovery, Exercise-Induced Oxidative Stress
- Trial name
- CURACTIVE (NCT07785986)
- Testing
- Curcumin, Ibuprofen
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Valladolid
Pain, Acute
Effects of Vibration Foam Rolling After Muscle Damage
Purpose: To compare the effects between non-vibration foam rolling (NVFR) and vibration foam rolling (VFR) on visual analogic scale (VAS), pressure pain threshold (PPT), oxygen saturation (SmO2), counter-movement jump (CMJ), and…
- Trial name
- NCT03662152
- Testing
- Foam roller, Vibration foam roller
- Where
- Spain
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Daniel Muñoz-Garcia
Exercise-induced Myocardial Damage, Right Ventricular Diastolic Dysfunction
Effects of Exogenous Ketones on Acute Changes and Recovery of the Heart Muscle After Intense Exercise.
It is well known that scar tissue on the heart muscle can cause (life-threatening) arrhythmias. However, the exact cause of this scar tissue is not entirely clear.
- Trial name
- NCT06715748
- Testing
- Ketone Monoester (KE)
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Jessa Hospital
Cold-water Immersion, Protein-carbohydrates Supplementation
Effects on CK, RPE, VAS Scale and Physical Performance of Three Recovery Methods in Elite Basketball Players
The aim of this study was to compare the effects of cold water intermittent ion (CWI), carbohydrate and protein supplementation (SUPPL), and active recovery (ACT) on creatine kinase (CK), perceptual and performance markers of…
- Conditions
- Cold-water Immersion, Protein-carbohydrates Supplementation, Active Recovery, Placebo
- Trial name
- NCT05805540
- Testing
- Cold-water immersion, Protein-carbohydrates supplementation, Active recovery
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Cadiz
Exercise-induced Muscle Damage, Movement Disorders
Neurodynamic Mobilization and Foam Rolling
The purpose of this study was to assess the acute effects of a single NM treatment session on DOMS and to compare them with those of one foam roller (FR) session.
- Conditions
- Exercise-induced Muscle Damage, Movement Disorders, Nerve Pain
- Trial name
- NCT03160937
- Testing
- Manual therapy
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Centro Universitario La Salle
Focus on Omega 3 Index on Recovery
Long-Term Omega-3 and Omega-3 Index >8%: Effects on Physiological Recovery
The Omega-3 Index measures how much of the Omega-3 fats EPA and DHA are built into red blood cell membranes. These fats are essential for health, but the body cannot make enough of them, so they must come from foods like oily…
- Trial name
- IMPROVE-8 (NCT07439601)
- Testing
- Oil Supplementation
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- St. Mary's University, Twickenham