Clinical trials: Exercise Metabolism, open to volunteers
Physical Activity, Childhood Obesity
The LEADS Trial (Linking Exericise for Advancing Daily Stress Management)
Chronic stressors have wide-reaching harmful effects on the physical, social, and psychological well-being of many African American (AA) families.
- Trial name
- LEADS (NCT07176234)
- Testing
- Treatment, Health Education
- Where
- 2 sites in United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Postpartum Urinary Incontinence, Postpartum Depression (PPD)
Prenatal Exercise Including Perineal Massage and Maternal-Neonatal Outcomes
The study is divided into three phases: Phase 1: Baseline survey to obtain an overall understanding of the current situation of voluntary participation in prenatal perineal massage.
- Conditions
- Postpartum Urinary Incontinence, Postpartum Depression (PPD), Neonatal Complications, Gestational Diabetes
- Trial name
- PEPM-RCT (NCT07314502)
- Testing
- Supervised prenatal exercise including antenatal perineal massage
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- South China Normal University
Exercise
Sex Differences in Cold-Induced Changes in Maximal Fat Oxidation
The purpose of this research study is to determine if the cold-induced change in fat burning during exercise is different between females and males.
- Trial name
- NCT07297823
- Testing
- Cold temperature, Room Temperature
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Overweight and Obesity
Home-Based Exercise for Adults Living With Overweight and Obesity
The study aims to implement a 12-week home-based exercise programme utilising an online intervention delivery platform. The focus will be on increasing exercise behaviour within the participant's home setting using aerobic…
- Trial name
- WEIGH (NCT05807386)
- Testing
- Home-based exercise programme
- Volunteers
- 30 people
- Sponsor
- Coventry University
Insomnia, Cardiorespiratory Fitness
Insomnia´s Impact on DNA Stability, Cardio-metabolic Health and Lifestyle Behaviors
Insomnia is a highly prevalent sleep disorder worldwide, with an increasing incidence in athletes, older adults, university students, and individuals with metabolic syndrome.
- Conditions
- Insomnia, Cardiorespiratory Fitness, Metabolic Disease
- Trial name
- INSIGHTS (NCT06869486)
- Testing
- Exercise, Bioelectrical Impedance, Micronucleus Assay
- Where
- Mexico
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Poly Cystic Ovary Syndrome, Overweight , Obesity
Physical Activity and Cardiometabolic Health in Women With or Without Polycystic Ovary Syndrome (SCOPAP)
The primary objective of this study is to investigate the effects of a multidisciplinary intervention, including a targeted adapted physical activity program, on lipid oxidation during a walking exercise in women with overweight…
- Trial name
- SCOPAP (NCT07659392)
- Testing
- Physical activity
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
Obesity (BMI>30), Metabolically Healthy Obesity
Plasma Taurine in Older Women With Obesity: Impact of Metabolic Phenotype and Combined Exercise
Population aging has been accompanied by a rise in obesity and other chronic diseases, increasing cardiovascular risk particularly among women, who exhibit a higher prevalence in older age groups compared to men.
- Conditions
- Obesity (BMI>30), Metabolically Healthy Obesity, Metabolically Unhealty Obese
- Trial name
- non applicable (NCT07711899)
- Testing
- Physical Training of 16 weeks
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Depression - Major Depressive Disorder, Overweight (BMI > 25)
Fasting, Exercise, and Diet to Activate Autophagy in Depression
Depression is a common mental health condition that affects millions of people worldwide and is a leading cause of disability. Although current treatments can be effective, many patients do not fully recover or experience…
- Trial name
- AutoFast (NCT07664540)
- Testing
- Performance test
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Friedreich's Ataxia
Cardiac Output and Fatigue in Friedreich's Ataxia
This is a clinical trial examining to impact of aerobic training plus omaveloxolone in FRDA. Thirty individuals with FRDA will be recruited; 20 individuals will be on omaveloxolone treatment whereas the other ten individuals will…
- Trial name
- NCT07444333
- Testing
- Aerobic Exercise
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Scott Barbuto
Nutritional Status, Nutrient Deficiency
Challenges in Achieving Adequate Dietary Status of Women
The aim of the study is to investigate the dietary habits of women of reproductive age (20-49 years). We aim to obtain epidemiological data on the intake and adequacy of key macronutrients and micronutrients, as well as to…
- Conditions
- Nutritional Status, Nutrient Deficiency, Micronutrient Deficiency, Vitamin D Deficiency
- Trial name
- NutriFem (NCT06745817)
- Testing
- Assessement of nutritional status, Dermis density and thickness, Skin elasticity
- Where
- 3 sites in Slovenia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition, Slovenia (Nutris)
Diabete Type 2, Aerobic Exercise
Type 2 Diabetes Mellitus and Downhill Aerobic Exercise Training
The purpose of this study is to compare the effects of an 8-week supervised downhill walking training program, prescribed based on the 6-minute walk test, on functional capacity, peripheral muscle strength, and cardiovascular…
- Conditions
- Diabete Type 2, Aerobic Exercise, Walking
- Trial name
- NCT07693296
- Testing
- Downhill Aerobic Walking Training, Level Aerobic Walking Training, Home exercise session
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Acibadem University
Overweight and Obese Adults, High Intensity Interval Exercise (HIIE)
Acute Effects of Isoenergetic HIIE vs. MICE on Key Parameters of Fat Mass Loss in Young Females With Overweight or Obesity
Overweight and obesity, particularly increased total and/or abdominal fat mass (FM), are strongly linked to the development of cardiovascular diseases.
- Trial name
- COMEFIT (NCT06868862)
- Testing
- Exercise
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques
Insulin Resistance, Obesity
Exercise Training on Brain Insulin Responsiveness
The overarching goal of the current study is to investigate the effect of one acute bout of exercise on the brain insulin responsiveness in a cross-over study design.
- Trial name
- acEx (NCT06039787)
- Testing
- single bout of moderate intensity continuous training (MICT), single bout of High Intensity Interval Training (HIIT), waiting control
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
M-health, Metabolic Syndrome
Exercise-Targeted Smart Lifestyle Management
To investigate the effects of simple dietary management and diet combined with exercise capacity-targeted intelligent lifestyle management on improving metabolic indicators in patients with overweight/obesity and metabolic…
- Conditions
- M-health, Metabolic Syndrome, Lifestyle Alteration, Lifestyle (Sedentary Behavior and Physical Activity)
- Trial name
- NCT07535333
- Testing
- Dietary Prescription, Personalized Exercise Prescription, Metabolic Syndrome Prevention and Education
- Volunteers
- 435 people
- Sponsor
- China National Center for Cardiovascular Diseases
Obesity
Tailoring Mobile Health Technology to Reduce Obesity and Improve Cardiovascular Health in Resource-Limited Neighborhood Environments
Background Obesity and physical inactivity contribute substantially to cardiovascular disease risk, diabetes, hypertension, and dyslipidemia.
- Trial name
- NCT03288207
- Testing
- AMRA(r) Researcher Image reconstruction software, MRI: radiofrequency coils (Device Manufacturer: Siemens Medical Solutions USA, Inc.), MRI: Research pulse sequences (Device Manufacturer: NIH)
- Where
- United States
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Obesity
LEAN Mass Preservation With Resistance Exercise and Protein During Semaglutide/Tirzepatide Therapy
The aim of the current study is to determine whether resistance exercise and/or protein intake can preserve lean mass and improve physical function in patients with obesity initiating semaglutide/tirzepatide therapy.
- Trial name
- LEAN-PREP (NCT06885736)
- Testing
- Resistance exercise, Protein Intake
- Where
- Kuwait
- Volunteers
- 232 people
- Sponsor
- Dasman Diabetes Institute
Physical Activities
Changes in Energy Expenditure in Response to Physical Activity in Healthy Adults
This study investigates how short, high-intensity body-weight exercises affect energy use in healthy young adults. The focus is on resting metabolic rate (RMR), total energy expenditure (TEE) and excess post-exercise oxygen…
- Trial name
- VITAL (NCT07529132)
- Testing
- physical activity
- Where
- Poland
- Volunteers
- 20 people
- Sponsor
- Medical University of Bialystok
Cancer, Advanced Solid Tumors, Malnutrition
A Nutrition and Exercise Program With Olanzapine Compared to Olanzapine Alone: A Trial in Patients With Advanced Tumors
Cancer patients have a higher risk of malnutrition because of their illness and treatments. This can lead to weight loss, weak muscles, less effective cancer therapy, or stronger side effects.
- Trial name
- SwissNutriAct2 (NCT07722806)
- Testing
- Standardized nutritional program, standardized exercize program, Whey protein supplement with added leucine and β-hydroxy-β-methylbutyrate (HMB)
- Where
- Switzerland
- Volunteers
- 130 people
- Sponsor
- Kantonsspital Winterthur KSW
Metabolic Syndrome, Prediabetes
Effects of Postprandial Walking and Resistance Snacking on Glucose Responses in Adults With Metabolic Syndrome
This study will examine whether light physical activity after meals can improve 24-hour glucose responses in adults with metabolic syndrome and prediabetes.
- Trial name
- BITE (NCT07620886)
- Testing
- Postprandial walking, Brief resistance exercise snacks
- Volunteers
- 25 people
- Sponsor
- Seoul National University
Obesity
Respiratory and Exercise Responses by Body Roundness Index in Obesity
This observational study aims to evaluate respiratory performance and exercise responses according to Body Roundness Index (BRI) in individuals with obesity.
- Trial name
- NCT07595822
- Testing
- Observational
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Biruni University