Clinical trials: Exercise Metabolism
Exercise Metabolism
Glucose-fructose Ratio Pilot
The aim of this pilot study is to estimate the effect size of changing the glucose-fructose ratio from 1:0.5 to 1:1 on exogenous carbohydrate oxidation rates during exercise, which can be used to power a future definitive study.
- Trial name
- NCT07360249
- Testing
- Glucose and fructose (one-to-one), Glucose and fructose (two-to-one)
- Where
- United Kingdom
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Bath
Hormonal Response, Mineral Metabolism
Effects of Chronic Exercise on Hormonal and Mineral Biomarkers in Male University Students
The purpose of this study is to investigate the effects of a high-intensity interval training (HIIT) program on hormonal and mineral biomarkers and aerobic fitness in male university students.
- Conditions
- Hormonal Response, Mineral Metabolism, Exercise Training
- Trial name
- NCT07893613
- Testing
- High-intensity interval training program
- Where
- Tunisia
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- High Institute of Sports and Physical Education of Kef
Cardiovascular Diseases, Natriuretic Peptides
GENESIS: Genotype Guided - Natriuretic Peptides - Cardiometabolic Health Study
Natriuretic Peptides (NP) are hormones produced by the heart, and they have a wide range of favorable metabolic benefits. Lower levels of these hormones are associated with an increased likelihood of the development of diabetes…
- Conditions
- Cardiovascular Diseases, Natriuretic Peptides, Cardiometabolic Diseases, Energy Expenditure
- Trial name
- NCT05216042
- Testing
- Study diet, Exercise capacity VO2 max determination, Exercise Challenge
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Cardiovascular Risk Markers, Postprandial Metabolism
Exercise Intensity and Postprandial Effects of Breaking Sedentary Behavior in Overweight Adults
The purpose of this study is twofold: (1) to determine whether breaking up prolonged sitting with aerobic or sprint cycling breaks reduces postprandial blood glucose, insulin, CRP, and blood pressure, which are established risk…
- Conditions
- Cardiovascular Risk Markers, Postprandial Metabolism, Exercise Physiology, Substrate Oxidation
- Trial name
- NCT07229963
- Testing
- Aerobic Exercise Intervention, Sprint Exercise Intervention, Sedentary Behaviour Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Cardiorespiratory Fitness, Substrate Metabolism During Exercise
VO2max and Substrate Crossover Point
This study aims to investigate the relationship between maximal oxygen uptake (VO2max) and the substrate crossover point during incremental exercise.
- Conditions
- Cardiorespiratory Fitness, Substrate Metabolism During Exercise, Metabolic Flexibility, Maximal Oxygen Uptake
- Trial name
- VO2MAX-CROSS (NCT07799662)
- Testing
- Incremental Graded Exercise Test (Bruce Protocol)
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Celil Kaçoğlu
Hydration Status, Substrate Metabolism During Exercise
The Effect of Hydration Status on Substrate Oxidation at Rest and During Light and Moderate Exercise
Metabolic flexibility is the ability to properly switch between fat and carbohydrate stores to use for energy under different conditions (rest, feeding, exercise).
- Trial name
- NCT07298863
- Testing
- Part 1 - Exercise Trial, Part 1 - Experimental Trial, Part 2 - Oral Glucose Tolerance Test
- Where
- 2 sites in United States, Canada
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Exercise Metabolism
Exogenous Carbohydrate Oxidation During High Intensity Exercise
The aim of the current project is to assess exogenous glucose oxidation rates during exercise at moderate and high intensity.
- Trial name
- Glucose ox (NCT07646665)
- Testing
- glucose
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Bath
Substrate Metabolism, Healthy Participants
Effects of Food Intake Sequence on Substrate Utilisation and Endurance Performance
The goal of this clinical trial is to understand how consuming a pre-exercise meal in different food intake sequences affects substrate utilisation and endurance exercise performance in healthy trained athletes.
- Conditions
- Substrate Metabolism, Healthy Participants, Endurance Exercise
- Trial name
- NCT07503990
- Testing
- Carbohydrate-last meal pattern, Carbohydrate-first meal pattern
- Where
- Portugal
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Energy Metabolism, Exercise
Energy Cost and Metabolic Intensity of Pilates Exercises in Older Adults
Pilates is one of the most popular forms of exercise among older adults worldwide. However, no study has measured how many calories a Pilates session burns or how hard the body works during it in people aged 60 and over.
- Conditions
- Energy Metabolism, Exercise, Aging
- Trial name
- NCT07621523
- Testing
- Mat Pilates, Equipment-Based Pilates, Treadmill Walking
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual do Norte do Parana
Fat Metabolism, Caffeine
Caffeine Strategies and Fat Oxidation
The goal of this clinical trial is to learn if different forms of caffeine ingestion can influence fat oxidation during submaximal cycling exercise.
- Conditions
- Fat Metabolism, Caffeine, Cycling, Exercise
- Trial name
- NCT07402902
- Testing
- Caffeine (Guinama Anhydrous Powder), Caffeine (Nescafé Classic Coffee), Caffeine (Kafewake Gum)
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Inflammation, Aging
Aging, Lifestyle and Inflammation in Veterans Exercising
Over half of adults in this country are overweight. This increases risk for heart and blood pressure problems, cancer, stroke and arthritis.
- Conditions
- Inflammation, Aging, Metabolism, Exercise
- Trial name
- ALIVE (NCT00667030)
- Testing
- Weight loss and aerobic exercise training
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Exercise Metabolism
The Effect of Acute Ketone Monoester Supplementation on Glucose Oxidation During Exercise
The purpose of this study is to examine the effect of exogenous ketone body supplementation on carbohydrate metabolism during exercise.
- Trial name
- KETONE (NCT06746805)
- Testing
- CHO+KETONE
- Where
- Netherlands
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Fat Metabolism, Sport Nutrition
The Effects of Acute Chicory Coffee Consumption on Exercise Performance and Metabolism
The goal of this clinical trial is to evaluate the acute effects of chicory coffee on metabolism and exercise performance in healthy, moderately active male participants aged 18-25.
- Conditions
- Fat Metabolism, Sport Nutrition, Exercise Metabolism, Inflammation
- Trial name
- NCT07094191
- Testing
- Chicory Coffee (Caffeine-free, polyphenol-rich beverage from roasted chicory root), arabica coffee, no beverage control
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Fatma Özsel Özcan
Exercise, Metabolism
Ketone Esters and Metabolism During Recovery from Endurance Exercise
Infusion of beta-hydroxybutyrate can suppress endogenous glucose production, which may result in increased net liver glycogen storage.
- Trial name
- NCT06846840
- Testing
- Ketone ester
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Bath
Oxidative Stress, Healthy
A Randomized, Double-Blind Study to Assess the Effect of a Postbiotic on Oxidative Stress and Exercise Performance
This is a prospective, randomized, placebo controlled, double-blind study to assess the effects of a postbiotic blend on exercise induced oxidative stress markers and exercise performance in healthy adult.
- Conditions
- Oxidative Stress, Healthy, Exercise-induced Muscle Damage, Exercise-induced Muscle Soreness
- Trial name
- PBE (NCT06795425)
- Testing
- Postbiotic Active Lifestyle Blend
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Exercise Metabolism
Body Weight and Carb Metabolism
Whilst theoretically, body size should influence the capacity for intestinal carbohydrate absorption and thus exogenous oxidation rates during exercise, there is currently little empirical evidence to support this hypothesis.
- Trial name
- NCT05330481
- Testing
- Moderate-intensity (relative) exercise with glucose ingestion, Moderate-intensity (absolute) exercise with glucose ingestion
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Bath
Lipid Metabolism, Substrate Metabolism
Body Composition and Lipid Metabolism at Rest and During Exercise: A Cross-Sectional Analysis.
The ability to upregulate fat oxidation at appropriate times such as during fasting, low to moderate intensity exercise and after a high fat meal, is popularly advocated.
- Conditions
- Lipid Metabolism, Substrate Metabolism, Exercise
- Trial name
- NCT03029364
- Testing
- Study Protocol
- Where
- United Kingdom
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of Bath
Sedentary Behavior, Lipid Metabolism Disorder
Preventing Exercise Resistance With Sedentary Interruptions
The goal of this randomised cross-over trial is to learn about the interaction between sedentary behaviour throughout the day and the metabolic effect of an exercise bout on that same day in office workers with an increased risk…
- Conditions
- Sedentary Behavior, Lipid Metabolism Disorder, Exercise
- Trial name
- PERSI (NCT06277713)
- Testing
- Standing interruptions, Exercise bout, Sedentary
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Aerobic Exercise, Acute Exercise
Diurnal Variation of Exercise on Metabolic Health
The main objective of this project is to study the diurnal variation of the effect of exercise on glycemic metabolism and fat oxidation in humans.
- Conditions
- Aerobic Exercise, Acute Exercise, Circadian Rhythm Sleep-Wake Disorders, Unspecified Type, Glucose Metabolism
- Trial name
- DIVA (NCT05369715)
- Testing
- Exercise
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Hypoxia, Cryostimulation
Evaluation of the Response to Hypoxia at Rest and During Exercise in a Healthy Subject After a Cryostimulation Exposure
Many information is available regarding human adaptations to cold or hypoxia. Adaptations to these environments and physical exercise constitute responses to physiological stress aimed at amplifying the organism's reactions and…
- Conditions
- Hypoxia, Cryostimulation, Metabolism, Autonomic Nervous System
- Trial name
- CRYOX (NCT06174480)
- Testing
- Cryostimulation
- Where
- 2 sites in France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital